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The map label for this gene is yitG [H]

Identifier: 52785908

GI number: 52785908

Start: 2106424

End: 2107668

Strand: Reverse

Name: yitG [H]

Synonym: BLi02158

Alternate gene names: 52785908

Gene position: 2107668-2106424 (Counterclockwise)

Preceding gene: 52785909

Following gene: 52785907

Centisome position: 49.91

GC content: 47.95

Gene sequence:

>1245_bases
ATGGCAGAAAAACAAAACTCTGGCATGACGGTTGTTGCTATCGGGTCGATCCCGTTGATTATGACGTTGGGAAATTCGAT
GCTGATTCCGATTTTGCCGAAAATGAAATCCGAACTCAATTTATCGCAATTTCAAGTCAGCCTTGTCATTACAGTGTTTT
CGATCACTGCAGCGCTCTTTATTCCGCTGCTCGGTTATTTGGCCGACCGCTTCTCACGGAAAGTGGTGATTATTCCGTGC
CTGTTCCTTTATGGGGCAGGGGGGATTCTTGCAGGGTTTGCATCGACGACCTTTGCGAATGCCTTCCCATGGGTGCTGTT
CGGGAGAGGACTGCAAGGGCTCGGGGCAGCCGGTACAGCGCCGATCGCAATGGCGCTGACAGGAGACCTTTTTAAAGGGG
CCGACGAAAGCCGGGTGCTCGGTCTTGTTGAAGCCTCGAACGGCTTCGGAAAAGTGCTGTCTCCTATTTTAGGATCATTG
ATTGCATTAATCGCTTGGTTTTGGGTGTTCTTTGCATTTCCGGCTTTTTGTATTGCGCCGATCATTTTGACTTGGATTTT
TATTAAAGAAAAAGACAAGAAAAAAGATCCGCCGCCTCTTGGAAAATATGTAAAAGGGCTGACAAGCGTTTTTAAACATG
AGGGCAGATGGCTTTTCACCGCATATCTCGCAGGAGCCGTCTGTTTGTTTACTCTGTTTGGCATCCTCTTTTACTTATCC
GATGTTTTGGAAAAAGAATATCATACAGACGGCGTAAAAAAAGGGCTGATTTTGGCGATCCCTCTGCTTGTGATGTGTAC
AACATCATATATTACGGGCAGCAAAATCGGACAAAATCAGCGGCTGATGAAAAAGATGATGGTCATCGGACTCGCTCTGA
TTACGGTTTCCTACGGCACACTGTCTTTTTTCTCCGCGCTCATTCCTTTTATTTCGATCCTTGTCATCAGCAGCATCGGC
ACAGGCTTTGTTCTGCCATGTGTCAACAGCTTCATAACCGGGGCTGTCGGAAAAGAGAGGCGCGGCTTTGTGACATCTCT
GTACGGTTCGGTCAGATTTTTAGGAGTCGCCATCGGACCGCCGATTTTCGGGAGACTGATGGAATGGTCGAAACTCGGCA
TGTTTATGTCCATAGCGGGCCTGACGTTGATTGTCGGTGTACTTGTGCTGACCATGATTCACGTCAAAAAGGAAGACACG
ACAAAAAAAGGGGACAAGGGGCTGCAGCCGGCTGACGCAAGATAG

Upstream 100 bases:

>100_bases
AAAAACGGCCGGAAACGAAGCTCAGCTGATGACGGATGCAACCCGAGCAGTTAACTCCAATTTTATAGTTCATTATGAAT
AAGGAAGGATGTACAAACTT

Downstream 100 bases:

>100_bases
GAGGAAAGGAAAAAACATGCGCATAGAAAAGGTTGACACATTTCCGCTGTTCCACAAGCTTTCCTCCCCTTACGGCGATG
CGAACGGATTGAAAAGCTAC

Product: YitG

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MAEKQNSGMTVVAIGSIPLIMTLGNSMLIPILPKMKSELNLSQFQVSLVITVFSITAALFIPLLGYLADRFSRKVVIIPC
LFLYGAGGILAGFASTTFANAFPWVLFGRGLQGLGAAGTAPIAMALTGDLFKGADESRVLGLVEASNGFGKVLSPILGSL
IALIAWFWVFFAFPAFCIAPIILTWIFIKEKDKKKDPPPLGKYVKGLTSVFKHEGRWLFTAYLAGAVCLFTLFGILFYLS
DVLEKEYHTDGVKKGLILAIPLLVMCTTSYITGSKIGQNQRLMKKMMVIGLALITVSYGTLSFFSALIPFISILVISSIG
TGFVLPCVNSFITGAVGKERRGFVTSLYGSVRFLGVAIGPPIFGRLMEWSKLGMFMSIAGLTLIVGVLVLTMIHVKKEDT
TKKGDKGLQPADAR

Sequences:

>Translated_414_residues
MAEKQNSGMTVVAIGSIPLIMTLGNSMLIPILPKMKSELNLSQFQVSLVITVFSITAALFIPLLGYLADRFSRKVVIIPC
LFLYGAGGILAGFASTTFANAFPWVLFGRGLQGLGAAGTAPIAMALTGDLFKGADESRVLGLVEASNGFGKVLSPILGSL
IALIAWFWVFFAFPAFCIAPIILTWIFIKEKDKKKDPPPLGKYVKGLTSVFKHEGRWLFTAYLAGAVCLFTLFGILFYLS
DVLEKEYHTDGVKKGLILAIPLLVMCTTSYITGSKIGQNQRLMKKMMVIGLALITVSYGTLSFFSALIPFISILVISSIG
TGFVLPCVNSFITGAVGKERRGFVTSLYGSVRFLGVAIGPPIFGRLMEWSKLGMFMSIAGLTLIVGVLVLTMIHVKKEDT
TKKGDKGLQPADAR
>Mature_413_residues
AEKQNSGMTVVAIGSIPLIMTLGNSMLIPILPKMKSELNLSQFQVSLVITVFSITAALFIPLLGYLADRFSRKVVIIPCL
FLYGAGGILAGFASTTFANAFPWVLFGRGLQGLGAAGTAPIAMALTGDLFKGADESRVLGLVEASNGFGKVLSPILGSLI
ALIAWFWVFFAFPAFCIAPIILTWIFIKEKDKKKDPPPLGKYVKGLTSVFKHEGRWLFTAYLAGAVCLFTLFGILFYLSD
VLEKEYHTDGVKKGLILAIPLLVMCTTSYITGSKIGQNQRLMKKMMVIGLALITVSYGTLSFFSALIPFISILVISSIGT
GFVLPCVNSFITGAVGKERRGFVTSLYGSVRFLGVAIGPPIFGRLMEWSKLGMFMSIAGLTLIVGVLVLTMIHVKKEDTT
KKGDKGLQPADAR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI1790146, Length=174, Percent_Identity=30.4597701149425, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI193209775, Length=174, Percent_Identity=28.1609195402299, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001958 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44640; Mature: 44509

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKQNSGMTVVAIGSIPLIMTLGNSMLIPILPKMKSELNLSQFQVSLVITVFSITAALF
CCCCCCCCEEEEEECCCCEEECCCCCCEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHH
IPLLGYLADRFSRKVVIIPCLFLYGAGGILAGFASTTFANAFPWVLFGRGLQGLGAAGTA
HHHHHHHHHHHCCCEEEEHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCC
PIAMALTGDLFKGADESRVLGLVEASNGFGKVLSPILGSLIALIAWFWVFFAFPAFCIAP
CCHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IILTWIFIKEKDKKKDPPPLGKYVKGLTSVFKHEGRWLFTAYLAGAVCLFTLFGILFYLS
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHH
DVLEKEYHTDGVKKGLILAIPLLVMCTTSYITGSKIGQNQRLMKKMMVIGLALITVSYGT
HHHHHHHHCCHHHCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LSFFSALIPFISILVISSIGTGFVLPCVNSFITGAVGKERRGFVTSLYGSVRFLGVAIGP
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCC
PIFGRLMEWSKLGMFMSIAGLTLIVGVLVLTMIHVKKEDTTKKGDKGLQPADAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AEKQNSGMTVVAIGSIPLIMTLGNSMLIPILPKMKSELNLSQFQVSLVITVFSITAALF
CCCCCCCEEEEEECCCCEEECCCCCCEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHH
IPLLGYLADRFSRKVVIIPCLFLYGAGGILAGFASTTFANAFPWVLFGRGLQGLGAAGTA
HHHHHHHHHHHCCCEEEEHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCC
PIAMALTGDLFKGADESRVLGLVEASNGFGKVLSPILGSLIALIAWFWVFFAFPAFCIAP
CCHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IILTWIFIKEKDKKKDPPPLGKYVKGLTSVFKHEGRWLFTAYLAGAVCLFTLFGILFYLS
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHH
DVLEKEYHTDGVKKGLILAIPLLVMCTTSYITGSKIGQNQRLMKKMMVIGLALITVSYGT
HHHHHHHHCCHHHCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LSFFSALIPFISILVISSIGTGFVLPCVNSFITGAVGKERRGFVTSLYGSVRFLGVAIGP
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCC
PIFGRLMEWSKLGMFMSIAGLTLIVGVLVLTMIHVKKEDTTKKGDKGLQPADAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]