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The map label for this gene is yitF [H]

Identifier: 52785907

GI number: 52785907

Start: 2105301

End: 2106407

Strand: Reverse

Name: yitF [H]

Synonym: BLi02157

Alternate gene names: 52785907

Gene position: 2106407-2105301 (Counterclockwise)

Preceding gene: 52785908

Following gene: 52785906

Centisome position: 49.88

GC content: 51.04

Gene sequence:

>1107_bases
ATGCGCATAGAAAAGGTTGACACATTTCCGCTGTTCCACAAGCTTTCCTCCCCTTACGGCGATGCGAACGGATTGAAAAG
CTACAGAACAAGCTATCTGATTCGGATTACGACAGCTTCAGGTCTGACAGGATGGGGAGAATGCGCGGATTGGCTGCCTG
CTTTGGATGCAGGCTTTAAAAAACGGATCATTCCTTATTTAATTGGAAAAGAAGCGAGCAATCGAACGGAGCTGATCACT
GTCATCAAAAAATGGCATCAGCGGGCCGCCTCTGCTGTAAGCATGGCTTTAACGGACATCACGGCGAAAAAAGCAGGCCT
TTCGGTATGCGAATTATGGGGAGGAAAACTGCGGGAGCAGATCCCGGTATATGCGTCATTCCAATCGTATTCAGACAGGC
CGGATTGGAGCCGCCATTCCCTCCGGCTTATCGAAAAGGCAGTTCGGGCCGGATTTAAGGCAGTCAAGCTGAAAGCGGGA
GGCAAGATGTTTTCAGAAGACTTGGCACATATTCAGGCCTTCCAGGAGATGACAGGGCAAAGCACCGGACTGATCCTCGA
TGCAAACCAGAGTTATGATCAGGCCGCCGCGCGCAAGTGGGAAACGTGGTTTTCCGGCTGGCAAAACGTGCTTTGGTTTG
AAGAGCCCATGCCGTTTGACGACCTAGCTGAATACCGGATGCTGCGCTCAGCGCTTTCTGTTCCGGTTGCCGGAGGAGAA
AACGTAAAAGGCGCAAAGCCGTTTTTGCCGATTTTTCTGGAGAACGCAGTCGATATTGCCCAGCCCGATGTTATGCACTG
TGAGGGCACGGACGAATTTCAAACCGTTCTGAAGCTCGCCAGGCATTTCGGAAAAAGGGTCTCTCCCCACAGCTATGACG
GCGGACTTTCAAGAATATACGCCGCTTTCGGACAAGCCTGTTTACCGCATTGGACCAAAATGGACGGAGAAGATATCGAA
CCGCTTGAATGGGATGCGATGGAGAATCCGTTCGCACAAATCGTGCCCGTCAGCATAAAAGACGGCTGCATTCAAGTCCC
CGACAAAATCGAAATTGATACAGAGCTCGTAGAAGCGTATGTGTGGGATGGCTCGTCTTACATCTGA

Upstream 100 bases:

>100_bases
CTTGTGCTGACCATGATTCACGTCAAAAAGGAAGACACGACAAAAAAAGGGGACAAGGGGCTGCAGCCGGCTGACGCAAG
ATAGGAGGAAAGGAAAAAAC

Downstream 100 bases:

>100_bases
TCAGCGTCCACCCCGAAAAAATGTGATATTTTTCATTTCCCCTTACATATAGTAGGAAAGAGGACAAGTTACTTTAAAGG
GGATTATATCCGTATGGGAA

Product: YitF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MRIEKVDTFPLFHKLSSPYGDANGLKSYRTSYLIRITTASGLTGWGECADWLPALDAGFKKRIIPYLIGKEASNRTELIT
VIKKWHQRAASAVSMALTDITAKKAGLSVCELWGGKLREQIPVYASFQSYSDRPDWSRHSLRLIEKAVRAGFKAVKLKAG
GKMFSEDLAHIQAFQEMTGQSTGLILDANQSYDQAAARKWETWFSGWQNVLWFEEPMPFDDLAEYRMLRSALSVPVAGGE
NVKGAKPFLPIFLENAVDIAQPDVMHCEGTDEFQTVLKLARHFGKRVSPHSYDGGLSRIYAAFGQACLPHWTKMDGEDIE
PLEWDAMENPFAQIVPVSIKDGCIQVPDKIEIDTELVEAYVWDGSSYI

Sequences:

>Translated_368_residues
MRIEKVDTFPLFHKLSSPYGDANGLKSYRTSYLIRITTASGLTGWGECADWLPALDAGFKKRIIPYLIGKEASNRTELIT
VIKKWHQRAASAVSMALTDITAKKAGLSVCELWGGKLREQIPVYASFQSYSDRPDWSRHSLRLIEKAVRAGFKAVKLKAG
GKMFSEDLAHIQAFQEMTGQSTGLILDANQSYDQAAARKWETWFSGWQNVLWFEEPMPFDDLAEYRMLRSALSVPVAGGE
NVKGAKPFLPIFLENAVDIAQPDVMHCEGTDEFQTVLKLARHFGKRVSPHSYDGGLSRIYAAFGQACLPHWTKMDGEDIE
PLEWDAMENPFAQIVPVSIKDGCIQVPDKIEIDTELVEAYVWDGSSYI
>Mature_368_residues
MRIEKVDTFPLFHKLSSPYGDANGLKSYRTSYLIRITTASGLTGWGECADWLPALDAGFKKRIIPYLIGKEASNRTELIT
VIKKWHQRAASAVSMALTDITAKKAGLSVCELWGGKLREQIPVYASFQSYSDRPDWSRHSLRLIEKAVRAGFKAVKLKAG
GKMFSEDLAHIQAFQEMTGQSTGLILDANQSYDQAAARKWETWFSGWQNVLWFEEPMPFDDLAEYRMLRSALSVPVAGGE
NVKGAKPFLPIFLENAVDIAQPDVMHCEGTDEFQTVLKLARHFGKRVSPHSYDGGLSRIYAAFGQACLPHWTKMDGEDIE
PLEWDAMENPFAQIVPVSIKDGCIQVPDKIEIDTELVEAYVWDGSSYI

Specific function: Unknown

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family [H]

Homologues:

Organism=Homo sapiens, GI42544119, Length=212, Percent_Identity=25.4716981132075, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI186972148, Length=212, Percent_Identity=25.4716981132075, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI226510960, Length=208, Percent_Identity=28.8461538461538, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015654
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: NA

Molecular weight: Translated: 41251; Mature: 41251

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIEKVDTFPLFHKLSSPYGDANGLKSYRTSYLIRITTASGLTGWGECADWLPALDAGFK
CCCCCCCCHHHHHHHCCCCCCCCHHHHHCCEEEEEEEECCCCCCHHHHHHHHHHHHCCHH
KRIIPYLIGKEASNRTELITVIKKWHQRAASAVSMALTDITAKKAGLSVCELWGGKLREQ
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCHHHHHC
IPVYASFQSYSDRPDWSRHSLRLIEKAVRAGFKAVKLKAGGKMFSEDLAHIQAFQEMTGQ
CCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCC
STGLILDANQSYDQAAARKWETWFSGWQNVLWFEEPMPFDDLAEYRMLRSALSVPVAGGE
CCCEEEECCCCHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCC
NVKGAKPFLPIFLENAVDIAQPDVMHCEGTDEFQTVLKLARHFGKRVSPHSYDGGLSRIY
CCCCCCCCHHHHHHCCHHHCCCCCEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
AAFGQACLPHWTKMDGEDIEPLEWDAMENPFAQIVPVSIKDGCIQVPDKIEIDTELVEAY
HHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCHHEEEEEECCCCEECCCCCCHHHHHHHHH
VWDGSSYI
HCCCCCCC
>Mature Secondary Structure
MRIEKVDTFPLFHKLSSPYGDANGLKSYRTSYLIRITTASGLTGWGECADWLPALDAGFK
CCCCCCCCHHHHHHHCCCCCCCCHHHHHCCEEEEEEEECCCCCCHHHHHHHHHHHHCCHH
KRIIPYLIGKEASNRTELITVIKKWHQRAASAVSMALTDITAKKAGLSVCELWGGKLREQ
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCHHHHHC
IPVYASFQSYSDRPDWSRHSLRLIEKAVRAGFKAVKLKAGGKMFSEDLAHIQAFQEMTGQ
CCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCC
STGLILDANQSYDQAAARKWETWFSGWQNVLWFEEPMPFDDLAEYRMLRSALSVPVAGGE
CCCEEEECCCCHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCC
NVKGAKPFLPIFLENAVDIAQPDVMHCEGTDEFQTVLKLARHFGKRVSPHSYDGGLSRIY
CCCCCCCCHHHHHHCCHHHCCCCCEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
AAFGQACLPHWTKMDGEDIEPLEWDAMENPFAQIVPVSIKDGCIQVPDKIEIDTELVEAY
HHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCHHEEEEEECCCCEECCCCCCHHHHHHHHH
VWDGSSYI
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353932; 9384377 [H]