BacMap

Definition	Bacillus licheniformis ATCC 14580, complete genome.
Accession	NC_006322
Length	4,222,645

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The map label for this gene is fadB [H]

Identifier: 52785856

GI number: 52785856

Start: 2045143

End: 2045928

Strand: Reverse

Name: fadB [H]

Synonym: BLi02103

Alternate gene names: 52785856

Gene position: 2045928-2045143 (Counterclockwise)

Preceding gene: 52785857

Following gene: 52785855

Centisome position: 48.45

GC content: 50.76

Gene sequence:

>786_bases
TTGAACTTGAAATATGCCACACTTAAAACAGAACATGGCATCACAACCGTGACGTTGAACAATCCGCCGGCAAATACACT
TTCTTCTTCCTGTATCGCCGAATTGCGCTCTCTTTTTCGGGAATTGGCCCGCGACGAGGAGACAAAAGCAATCATCATTA
CTGGAGAAGGCCGCTTTTTTGTGGCGGGAGCGGATATAAAAGAATTCGTTTCAAAACTTGGGGACCAAAAACAAGGATTG
GCGCTCGCACAAGGGGGCCAGGCGCTCTGCGATGAAATCGAAGCTTCCAAAAAACCCGTCATTGCGGCGATAAACGGACC
GGCTCTTGGCGGAGGCCTGGAACTCGCGATGAGCTGCCACTTCAGAATCGTATCAGACGATGCAACAGTCGGTCTTCCCG
AATTAAAGCTCGGCTTGATTCCTGCATTTGGTGGTACACAGCGGCTTCGCAACATAACGGACACAGCGACAGCACTCGAC
CTTATCCTGACGGGCCGATCGCTTTCAGCTCAAGAGGCGGTAGAGCTGAAAATTGCACAGATGGCTGTAAAGGGAGAGGA
ACTGATGAAGACGGCAGCTGCTGTCGCGTCGTCTTTTATCGAAGGAAAAAGCATGACCAGCGTGAGGCGCGCCGTCGAAT
GTGTCGTACAGGGCGCCAGCGAAAGCATGGAACAAGCACTGGAGAGGGAGCGAAACAGATTCGCCGAGCTGTTTGTCACT
TCAGATGCCAAAGAAGGAATTCACGCATTTGTCGAAAAGCGCAAACCAAACTTTCATCATTCATAA

Upstream 100 bases:

>100_bases
ACCGAACGCTGGTTCTAATCCTTAACATAAGGCTCCCTCTCATGCACAACTGATTTTTTTTCAGAGGGGCCTTTTTTATT
TAATCAGGGAGGGATCAATA

Downstream 100 bases:

>100_bases
AAGGAGTGGATCAAGATGTCCGATGACGTGCTGTTTTCCGTCAATCAAAACGGCGCCGCAGCGATTGTTCTGAATCGCCC
GAAAGCGCTCAACTCACTCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MNLKYATLKTEHGITTVTLNNPPANTLSSSCIAELRSLFRELARDEETKAIIITGEGRFFVAGADIKEFVSKLGDQKQGL
ALAQGGQALCDEIEASKKPVIAAINGPALGGGLELAMSCHFRIVSDDATVGLPELKLGLIPAFGGTQRLRNITDTATALD
LILTGRSLSAQEAVELKIAQMAVKGEELMKTAAAVASSFIEGKSMTSVRRAVECVVQGASESMEQALERERNRFAELFVT
SDAKEGIHAFVEKRKPNFHHS

Sequences:

>Translated_261_residues
MNLKYATLKTEHGITTVTLNNPPANTLSSSCIAELRSLFRELARDEETKAIIITGEGRFFVAGADIKEFVSKLGDQKQGL
ALAQGGQALCDEIEASKKPVIAAINGPALGGGLELAMSCHFRIVSDDATVGLPELKLGLIPAFGGTQRLRNITDTATALD
LILTGRSLSAQEAVELKIAQMAVKGEELMKTAAAVASSFIEGKSMTSVRRAVECVVQGASESMEQALERERNRFAELFVT
SDAKEGIHAFVEKRKPNFHHS
>Mature_261_residues
MNLKYATLKTEHGITTVTLNNPPANTLSSSCIAELRSLFRELARDEETKAIIITGEGRFFVAGADIKEFVSKLGDQKQGL
ALAQGGQALCDEIEASKKPVIAAINGPALGGGLELAMSCHFRIVSDDATVGLPELKLGLIPAFGGTQRLRNITDTATALD
LILTGRSLSAQEAVELKIAQMAVKGEELMKTAAAVASSFIEGKSMTSVRRAVECVVQGASESMEQALERERNRFAELFVT
SDAKEGIHAFVEKRKPNFHHS

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI68989263, Length=281, Percent_Identity=33.4519572953737, Blast_Score=134, Evalue=9e-32,
Organism=Homo sapiens, GI194097323, Length=245, Percent_Identity=36.734693877551, Blast_Score=130, Evalue=8e-31,
Organism=Homo sapiens, GI20127408, Length=175, Percent_Identity=37.7142857142857, Blast_Score=114, Evalue=8e-26,
Organism=Homo sapiens, GI31542718, Length=253, Percent_Identity=29.2490118577075, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI157694516, Length=234, Percent_Identity=26.9230769230769, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI70995211, Length=266, Percent_Identity=26.3157894736842, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI213417737, Length=234, Percent_Identity=26.9230769230769, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI261878539, Length=182, Percent_Identity=33.5164835164835, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI4502327, Length=264, Percent_Identity=32.5757575757576, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI150378541, Length=254, Percent_Identity=28.3464566929134, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI37594471, Length=177, Percent_Identity=30.5084745762712, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI157694520, Length=201, Percent_Identity=25.8706467661692, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI37594469, Length=177, Percent_Identity=30.5084745762712, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI62530384, Length=191, Percent_Identity=27.2251308900524, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI221307494, Length=170, Percent_Identity=27.0588235294118, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI221136756, Length=263, Percent_Identity=23.574144486692, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI221136753, Length=263, Percent_Identity=23.574144486692, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI116235487, Length=170, Percent_Identity=27.6470588235294, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4757968, Length=259, Percent_Identity=23.1660231660232, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI49355787, Length=259, Percent_Identity=23.1660231660232, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787659, Length=254, Percent_Identity=33.0708661417323, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI221142681, Length=251, Percent_Identity=34.2629482071713, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1788682, Length=188, Percent_Identity=38.2978723404255, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1790281, Length=202, Percent_Identity=31.1881188118812, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787660, Length=261, Percent_Identity=30.2681992337165, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87082183, Length=262, Percent_Identity=26.7175572519084, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788597, Length=252, Percent_Identity=23.4126984126984, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17554946, Length=259, Percent_Identity=36.2934362934363, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI25145438, Length=252, Percent_Identity=33.7301587301587, Blast_Score=135, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17558304, Length=175, Percent_Identity=38.8571428571429, Blast_Score=120, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI25144276, Length=155, Percent_Identity=41.9354838709677, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17508953, Length=155, Percent_Identity=41.9354838709677, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17508951, Length=155, Percent_Identity=41.9354838709677, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17540714, Length=229, Percent_Identity=32.7510917030568, Blast_Score=111, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17540306, Length=251, Percent_Identity=26.6932270916335, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17560910, Length=240, Percent_Identity=30.8333333333333, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17536985, Length=260, Percent_Identity=25, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17534483, Length=275, Percent_Identity=24, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI25141363, Length=171, Percent_Identity=26.9005847953216, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320241, Length=189, Percent_Identity=26.4550264550265, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI20129971, Length=267, Percent_Identity=36.7041198501873, Blast_Score=154, Evalue=8e-38,
Organism=Drosophila melanogaster, GI24653477, Length=267, Percent_Identity=36.7041198501873, Blast_Score=154, Evalue=8e-38,
Organism=Drosophila melanogaster, GI24653139, Length=264, Percent_Identity=32.1969696969697, Blast_Score=118, Evalue=5e-27,
Organism=Drosophila melanogaster, GI19921000, Length=218, Percent_Identity=36.697247706422, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24583077, Length=218, Percent_Identity=36.697247706422, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24583079, Length=218, Percent_Identity=36.697247706422, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI19922422, Length=256, Percent_Identity=25.78125, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI21357171, Length=264, Percent_Identity=26.8939393939394, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19921018, Length=188, Percent_Identity=28.1914893617021, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19920382, Length=255, Percent_Identity=23.921568627451, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583165, Length=188, Percent_Identity=28.1914893617021, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24650670, Length=176, Percent_Identity=27.8409090909091, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24654903, Length=238, Percent_Identity=24.7899159663866, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 27986; Mature: 27986

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKYATLKTEHGITTVTLNNPPANTLSSSCIAELRSLFRELARDEETKAIIITGEGRFF
CCCEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEE
VAGADIKEFVSKLGDQKQGLALAQGGQALCDEIEASKKPVIAAINGPALGGGLELAMSCH
EECCCHHHHHHHHCCCCCCCEECCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHEEEEEE
FRIVSDDATVGLPELKLGLIPAFGGTQRLRNITDTATALDLILTGRSLSAQEAVELKIAQ
EEEEECCCCCCCCCHHEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
MAVKGEELMKTAAAVASSFIEGKSMTSVRRAVECVVQGASESMEQALERERNRFAELFVT
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHEEE
SDAKEGIHAFVEKRKPNFHHS
CCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNLKYATLKTEHGITTVTLNNPPANTLSSSCIAELRSLFRELARDEETKAIIITGEGRFF
CCCEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCEEE
VAGADIKEFVSKLGDQKQGLALAQGGQALCDEIEASKKPVIAAINGPALGGGLELAMSCH
EECCCHHHHHHHHCCCCCCCEECCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHEEEEEE
FRIVSDDATVGLPELKLGLIPAFGGTQRLRNITDTATALDLILTGRSLSAQEAVELKIAQ
EEEEECCCCCCCCCHHEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
MAVKGEELMKTAAAVASSFIEGKSMTSVRRAVECVVQGASESMEQALERERNRFAELFVT
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHEEE
SDAKEGIHAFVEKRKPNFHHS
CCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]