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The map label for this gene is pbpE [H]

Identifier: 52785705

GI number: 52785705

Start: 1907381

End: 1908397

Strand: Reverse

Name: pbpE [H]

Synonym: BLi01947

Alternate gene names: 52785705

Gene position: 1908397-1907381 (Counterclockwise)

Preceding gene: 52785708

Following gene: 52785704

Centisome position: 45.19

GC content: 41.99

Gene sequence:

>1017_bases
TTGGTATATACAGCGGAACATCTTGATGATTATTTAATGGAACAAGCATCCAACAATCATTTTCACGGCAGCATTTTGCT
GGCAGATTCAAACGGTATACTGTTATCGAAAGGATACGGTTATGCCAATTGTAAGGACAAGGTGAAGAATGAACCGTCTA
CACGCTACCAAATTGCCTCACTGACAAAGCAATTCACAGCTATAGCGGTCATGCAGCTGCAAGAAAAGGGGCTGCTTCGT
ACAGATGACCCGGTACAAAACTATTTAGAAGGCTATCCGAACGGCGACAGCATTACCATCAAACATTTATTAAGCCATAC
GTCCGGAATTCCTGATTTTCTAGAGGAAGAATTGCTCGATATTGAGCTGGAGCGCGCACCGTTGGACCAATTTATCAGAC
GTTTTATTGACAAGCCGCTTGAATTTCGGCCGGGACAAAGGTTCAATTACAGTAATTCAGGATACATACTGCTTACAAAA
ATCATTGAAACGATCACAAATGAAGCTTATGGAGACGTTATTCAACAATTGATCTTTGACCCTTTAGGCATGAAAAACTC
CGGTTTTTTCTCTTCTCCGGAAGATATTTCGCCTACAGTCGGATATTTATGCCTGAATCGTGAAATGATCAAAGCGCCTA
TCGTATACGGCTACGGGGAAAGCGGGCTGTATTCAACCGTTGAAGACTTGTACTTATGGGACAGGGCGCTTTACACCGAG
AAGCTTGTCTCAAAAGATGCTTTGAAAGAAGCCCTTTACAGCCGCGTCAAAAAGCAGGCTTTTGCAGCCGAAGGCCCTTC
TCCGGCGCTCATTCAAAACAATTCGATCGGATACGGATGGTTTATTAATCATCAAAATAAGTATAAAATATGGCATGATG
GAGAAATCCACGGTTTTATCAGCTCAATTAACCGATACATGGATGAGAAAAAAGTGCTGATTATGCTCAGCAATTGCAAC
CTCTCAAAAACTGACGAGATTTTGGCACACTTAGAAGAAGCTTTATTGCAAATGTAG

Upstream 100 bases:

>100_bases
TATAATGTTATTTTGGTCGCGCTTCCTGCTTCATTTCCTTTCAAAACTATCGTTTATTGTTTTCTTCTTATCATAATTAG
ATATGAAAGGACTGTTGTTA

Downstream 100 bases:

>100_bases
AAGCTAAAGACAAAGAAAGGCAGCGGGAGCGGTATGATCAGAAAACTATTCACTATCATCATCATGGCAAGTATCATCGC
GGTCGGATTCGTCTGCAAAG

Product: hypothetical protein

Products: NA

Alternate protein names: PBP 4*; PBP 4A; Penicillin-binding protein E [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MVYTAEHLDDYLMEQASNNHFHGSILLADSNGILLSKGYGYANCKDKVKNEPSTRYQIASLTKQFTAIAVMQLQEKGLLR
TDDPVQNYLEGYPNGDSITIKHLLSHTSGIPDFLEEELLDIELERAPLDQFIRRFIDKPLEFRPGQRFNYSNSGYILLTK
IIETITNEAYGDVIQQLIFDPLGMKNSGFFSSPEDISPTVGYLCLNREMIKAPIVYGYGESGLYSTVEDLYLWDRALYTE
KLVSKDALKEALYSRVKKQAFAAEGPSPALIQNNSIGYGWFINHQNKYKIWHDGEIHGFISSINRYMDEKKVLIMLSNCN
LSKTDEILAHLEEALLQM

Sequences:

>Translated_338_residues
MVYTAEHLDDYLMEQASNNHFHGSILLADSNGILLSKGYGYANCKDKVKNEPSTRYQIASLTKQFTAIAVMQLQEKGLLR
TDDPVQNYLEGYPNGDSITIKHLLSHTSGIPDFLEEELLDIELERAPLDQFIRRFIDKPLEFRPGQRFNYSNSGYILLTK
IIETITNEAYGDVIQQLIFDPLGMKNSGFFSSPEDISPTVGYLCLNREMIKAPIVYGYGESGLYSTVEDLYLWDRALYTE
KLVSKDALKEALYSRVKKQAFAAEGPSPALIQNNSIGYGWFINHQNKYKIWHDGEIHGFISSINRYMDEKKVLIMLSNCN
LSKTDEILAHLEEALLQM
>Mature_338_residues
MVYTAEHLDDYLMEQASNNHFHGSILLADSNGILLSKGYGYANCKDKVKNEPSTRYQIASLTKQFTAIAVMQLQEKGLLR
TDDPVQNYLEGYPNGDSITIKHLLSHTSGIPDFLEEELLDIELERAPLDQFIRRFIDKPLEFRPGQRFNYSNSGYILLTK
IIETITNEAYGDVIQQLIFDPLGMKNSGFFSSPEDISPTVGYLCLNREMIKAPIVYGYGESGLYSTVEDLYLWDRALYTE
KLVSKDALKEALYSRVKKQAFAAEGPSPALIQNNSIGYGWFINHQNKYKIWHDGEIHGFISSINRYMDEKKVLIMLSNCN
LSKTDEILAHLEEALLQM

Specific function: Probably involved in peptidoglycan modification during cortex synthesis [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-lactamase family [H]

Homologues:

Organism=Escherichia coli, GI87082101, Length=201, Percent_Identity=26.865671641791, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786574, Length=314, Percent_Identity=22.6114649681529, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17550934, Length=321, Percent_Identity=26.4797507788162, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115533026, Length=344, Percent_Identity=25.2906976744186, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466
- InterPro:   IPR021860 [H]

Pfam domain/function: PF00144 Beta-lactamase; PF11954 DUF3471 [H]

EC number: NA

Molecular weight: Translated: 38494; Mature: 38494

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVYTAEHLDDYLMEQASNNHFHGSILLADSNGILLSKGYGYANCKDKVKNEPSTRYQIAS
CCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEECCCCCCCCHHHHCCCCCHHHHHHH
LTKQFTAIAVMQLQEKGLLRTDDPVQNYLEGYPNGDSITIKHLLSHTSGIPDFLEEELLD
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHC
IELERAPLDQFIRRFIDKPLEFRPGQRFNYSNSGYILLTKIIETITNEAYGDVIQQLIFD
CCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCHHHHHHHHHHHHC
PLGMKNSGFFSSPEDISPTVGYLCLNREMIKAPIVYGYGESGLYSTVEDLYLWDRALYTE
CCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHH
KLVSKDALKEALYSRVKKQAFAAEGPSPALIQNNSIGYGWFINHQNKYKIWHDGEIHGFI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEEEEECCCCEEEEECCHHHHHH
SSINRYMDEKKVLIMLSNCNLSKTDEILAHLEEALLQM
HHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVYTAEHLDDYLMEQASNNHFHGSILLADSNGILLSKGYGYANCKDKVKNEPSTRYQIAS
CCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEECCCCCCCCHHHHCCCCCHHHHHHH
LTKQFTAIAVMQLQEKGLLRTDDPVQNYLEGYPNGDSITIKHLLSHTSGIPDFLEEELLD
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHC
IELERAPLDQFIRRFIDKPLEFRPGQRFNYSNSGYILLTKIIETITNEAYGDVIQQLIFD
CCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCHHHHHHHHHHHHC
PLGMKNSGFFSSPEDISPTVGYLCLNREMIKAPIVYGYGESGLYSTVEDLYLWDRALYTE
CCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHH
KLVSKDALKEALYSRVKKQAFAAEGPSPALIQNNSIGYGWFINHQNKYKIWHDGEIHGFI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEEEEECCCCEEEEECCHHHHHH
SSINRYMDEKKVLIMLSNCNLSKTDEILAHLEEALLQM
HHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8491712; 9384377 [H]