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The map label for this gene is yhxB [H]

Identifier: 52784769

GI number: 52784769

Start: 1000886

End: 1002634

Strand: Direct

Name: yhxB [H]

Synonym: BLi00997

Alternate gene names: 52784769

Gene position: 1000886-1002634 (Clockwise)

Preceding gene: 52784768

Following gene: 52784770

Centisome position: 23.7

GC content: 49.63

Gene sequence:

>1749_bases
ATGAGCTGGAGAACGAGCTATGAACGCTGGAGAAACAAAGAAAACTTAGATTCCGAATTAAAAGCGCTTCTTTTGGAAGC
GGAAGGAAATGAAAAAGAACTAGAGGATTGCTTTTATAAAAAACTTGAGTTTGGTACAGCCGGTATGCGCGGTGAGATCG
GACCGGGCCCGAACCGCATGAACGTTTATACGGTTCGCAAAGCATCGGCGGGCCTTGCCGCATACATAGGAGCGAACGGC
GGCGAAGCAAAAAAGCGCGGCGTTGTGATCGCGTACGATTCCCGCCACAAATCGCCTGAATTTGCAATGGAAGCTGCTAA
GACGCTCGCAGAAAACGGCGTTCAAACGTACGTGTTTGACGAACTGCGCCCGACACCTGAACTTTCCTTTGCGGTAAGAG
AACTGAATGCGTTTGCAGGTATTGTCATCACGGCGAGCCATAACCCGCCTGAATACAACGGCTATAAAGTGTACGGAGAG
GACGGCGCGCAGCTTCCGCCTGCTGATGCCGACAAACTCACCGGCTATGTCAATGCGATAGAAAACGAACTGGAAATCGA
AGCCGGAGATGAAGCTGCTTTAACCGAAAAAGGGCTGATTAAAATAATCGGCGAGGAAATCGATCAAGCGTATCTCGATA
AACTGACATCGATTTCTGTCAACCCTGATCTGGCAAAGGAGACCGAAGTCAAAGTCATCTTCACCCCGCTTCACGGCACG
GCAAACAAGTCTGTCAGACGGGGCCTGAAAGCTCTCGGGTATGAACATGTCACAGTCGTCCCCGAACAGGAGCTCCCTGA
CCCTGACTTTTCGACCGTATCTTCTCCGAATCCGGAAGAGCACGCCGCTTTTGAATATGCGATCAGACTAGGAGAAGAAA
ATGGAGCCGACATTCTGATCGGAACCGATCCAGACGCAGACCGGCTCGGCGTCGCTGTAAAGGATCAAGAAGGCCGCTAC
GTAGTGCTGACAGGAAATCAAACCGGCGCGCTGCTCCTGCATTATCTGCTGTCGCAAAAACAGCAGAAAGGCATGCTGCC
TGATAACGGCGTCGTTCTGAAAACGATTGTGACGAGCGAAATGGGGCGCGACATCGCCGCTTCTTTCGGACTGGACACGA
TCGACACGCTGACCGGCTTTAAATTCATCGGAGAAAAAATCAAACAATTTGAAGCATCGGGCGAATATGCTTTCCAATTC
GGTTATGAGGAAAGCTACGGCTACTTGATCGGCGACTTCGCAAGGGACAAGGATGCCGTCCAGGCCGCACTGCTTGCCGT
TGAAGTATGCGCCTTCTATAAAAAGCAGGGAAAATCGCTTTATGACGGGCTCCTCGAATTGTATAAATCGTTCGGCTTCT
ATAGAGAAGGCTTGAAGTCCCTGACCTTAAAAGGAAAAGAGGGAGCGGAGCAAATCGCAGCCATCCTCAGCACATTCAGA
GAACAGCCGCCTCTTTCCATCGCCGGAAAAGATGTCGTATCCGCCGAAGACTATTTGACAGGGAAGCGGACGCTGCTAAA
GGAAAACAAAAGGGAAACGATCGACCTTCCGAAATCCAATGTTTTGAAATATTTCCTTGAAGACGGCTCATGGTTCTGCC
TCCGTCCATCAGGAACAGAGCCTAAAGTGAAATTTTATTTCGCGGTCAAAGGCCGAACCAATGAAGAAAGCGAAGCGCTT
CTCAATCAATTGACAGACGAAGTGATGAAAAAAATCGACGATATTGTAAAAGCGACCTCAAATTCGTAA

Upstream 100 bases:

>100_bases
CATTTTTTTCATTTGGCATGCTAAATTTGGACAAAGCGGCGGTTTGTCGATATGATAAAAGAAAAGCTGCAATTACTTAG
CTAGAACATTGGAGGTAATC

Downstream 100 bases:

>100_bases
TCGCTGAAAACCCGCCTTTAAATGGCGGGTTTTTTTATTGTGAAGAGACGATGAATGATGTAATATATATTTAACATTAG
GTCATATATAAATTGCATAT

Product: YhxB

Products: NA

Alternate protein names: PGM; Alpha-phosphoglucomutase; Glucose phosphomutase [H]

Number of amino acids: Translated: 582; Mature: 581

Protein sequence:

>582_residues
MSWRTSYERWRNKENLDSELKALLLEAEGNEKELEDCFYKKLEFGTAGMRGEIGPGPNRMNVYTVRKASAGLAAYIGANG
GEAKKRGVVIAYDSRHKSPEFAMEAAKTLAENGVQTYVFDELRPTPELSFAVRELNAFAGIVITASHNPPEYNGYKVYGE
DGAQLPPADADKLTGYVNAIENELEIEAGDEAALTEKGLIKIIGEEIDQAYLDKLTSISVNPDLAKETEVKVIFTPLHGT
ANKSVRRGLKALGYEHVTVVPEQELPDPDFSTVSSPNPEEHAAFEYAIRLGEENGADILIGTDPDADRLGVAVKDQEGRY
VVLTGNQTGALLLHYLLSQKQQKGMLPDNGVVLKTIVTSEMGRDIAASFGLDTIDTLTGFKFIGEKIKQFEASGEYAFQF
GYEESYGYLIGDFARDKDAVQAALLAVEVCAFYKKQGKSLYDGLLELYKSFGFYREGLKSLTLKGKEGAEQIAAILSTFR
EQPPLSIAGKDVVSAEDYLTGKRTLLKENKRETIDLPKSNVLKYFLEDGSWFCLRPSGTEPKVKFYFAVKGRTNEESEAL
LNQLTDEVMKKIDDIVKATSNS

Sequences:

>Translated_582_residues
MSWRTSYERWRNKENLDSELKALLLEAEGNEKELEDCFYKKLEFGTAGMRGEIGPGPNRMNVYTVRKASAGLAAYIGANG
GEAKKRGVVIAYDSRHKSPEFAMEAAKTLAENGVQTYVFDELRPTPELSFAVRELNAFAGIVITASHNPPEYNGYKVYGE
DGAQLPPADADKLTGYVNAIENELEIEAGDEAALTEKGLIKIIGEEIDQAYLDKLTSISVNPDLAKETEVKVIFTPLHGT
ANKSVRRGLKALGYEHVTVVPEQELPDPDFSTVSSPNPEEHAAFEYAIRLGEENGADILIGTDPDADRLGVAVKDQEGRY
VVLTGNQTGALLLHYLLSQKQQKGMLPDNGVVLKTIVTSEMGRDIAASFGLDTIDTLTGFKFIGEKIKQFEASGEYAFQF
GYEESYGYLIGDFARDKDAVQAALLAVEVCAFYKKQGKSLYDGLLELYKSFGFYREGLKSLTLKGKEGAEQIAAILSTFR
EQPPLSIAGKDVVSAEDYLTGKRTLLKENKRETIDLPKSNVLKYFLEDGSWFCLRPSGTEPKVKFYFAVKGRTNEESEAL
LNQLTDEVMKKIDDIVKATSNS
>Mature_581_residues
SWRTSYERWRNKENLDSELKALLLEAEGNEKELEDCFYKKLEFGTAGMRGEIGPGPNRMNVYTVRKASAGLAAYIGANGG
EAKKRGVVIAYDSRHKSPEFAMEAAKTLAENGVQTYVFDELRPTPELSFAVRELNAFAGIVITASHNPPEYNGYKVYGED
GAQLPPADADKLTGYVNAIENELEIEAGDEAALTEKGLIKIIGEEIDQAYLDKLTSISVNPDLAKETEVKVIFTPLHGTA
NKSVRRGLKALGYEHVTVVPEQELPDPDFSTVSSPNPEEHAAFEYAIRLGEENGADILIGTDPDADRLGVAVKDQEGRYV
VLTGNQTGALLLHYLLSQKQQKGMLPDNGVVLKTIVTSEMGRDIAASFGLDTIDTLTGFKFIGEKIKQFEASGEYAFQFG
YEESYGYLIGDFARDKDAVQAALLAVEVCAFYKKQGKSLYDGLLELYKSFGFYREGLKSLTLKGKEGAEQIAAILSTFRE
QPPLSIAGKDVVSAEDYLTGKRTLLKENKRETIDLPKSNVLKYFLEDGSWFCLRPSGTEPKVKFYFAVKGRTNEESEALL
NQLTDEVMKKIDDIVKATSNS

Specific function: Catalyzes the interconversion between glucose-6- phosphate and alpha-glucose-1-phosphate. This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI63055049, Length=556, Percent_Identity=33.9928057553957, Blast_Score=300, Evalue=2e-81,
Organism=Homo sapiens, GI31377548, Length=588, Percent_Identity=32.1428571428571, Blast_Score=273, Evalue=5e-73,
Organism=Escherichia coli, GI1786904, Length=562, Percent_Identity=25.9786476868327, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1788361, Length=377, Percent_Identity=27.0557029177719, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789566, Length=404, Percent_Identity=26.2376237623762, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71993870, Length=574, Percent_Identity=31.7073170731707, Blast_Score=254, Evalue=1e-67,
Organism=Caenorhabditis elegans, GI71993878, Length=312, Percent_Identity=32.0512820512821, Blast_Score=151, Evalue=7e-37,
Organism=Saccharomyces cerevisiae, GI6323934, Length=596, Percent_Identity=31.8791946308725, Blast_Score=233, Evalue=5e-62,
Organism=Drosophila melanogaster, GI20129809, Length=556, Percent_Identity=30.7553956834532, Blast_Score=253, Evalue=2e-67,
Organism=Drosophila melanogaster, GI24651977, Length=459, Percent_Identity=32.0261437908497, Blast_Score=231, Evalue=1e-60,
Organism=Drosophila melanogaster, GI24653722, Length=591, Percent_Identity=27.2419627749577, Blast_Score=205, Evalue=7e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 64212; Mature: 64081

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWRTSYERWRNKENLDSELKALLLEAEGNEKELEDCFYKKLEFGTAGMRGEIGPGPNRM
CCCCCCHHHHCCCCCHHHHHHHEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
NVYTVRKASAGLAAYIGANGGEAKKRGVVIAYDSRHKSPEFAMEAAKTLAENGVQTYVFD
EEEEEEECCCCEEEEEECCCCCHHHCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEC
ELRPTPELSFAVRELNAFAGIVITASHNPPEYNGYKVYGEDGAQLPPADADKLTGYVNAI
CCCCCCCHHHHHHHHHHHEEEEEEECCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHH
ENELEIEAGDEAALTEKGLIKIIGEEIDQAYLDKLTSISVNPDLAKETEVKVIFTPLHGT
CCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEEEEECCCCC
ANKSVRRGLKALGYEHVTVVPEQELPDPDFSTVSSPNPEEHAAFEYAIRLGEENGADILI
CCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHEEECCCCCCEEEE
GTDPDADRLGVAVKDQEGRYVVLTGNQTGALLLHYLLSQKQQKGMLPDNGVVLKTIVTSE
ECCCCHHHCCEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHH
MGRDIAASFGLDTIDTLTGFKFIGEKIKQFEASGEYAFQFGYEESYGYLIGDFARDKDAV
HCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEECHHCCHHHH
QAALLAVEVCAFYKKQGKSLYDGLLELYKSFGFYREGLKSLTLKGKEGAEQIAAILSTFR
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHH
EQPPLSIAGKDVVSAEDYLTGKRTLLKENKRETIDLPKSNVLKYFLEDGSWFCLRPSGTE
CCCCCCCCCCCCCCHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCC
PKVKFYFAVKGRTNEESEALLNQLTDEVMKKIDDIVKATSNS
CCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SWRTSYERWRNKENLDSELKALLLEAEGNEKELEDCFYKKLEFGTAGMRGEIGPGPNRM
CCCCCHHHHCCCCCHHHHHHHEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCE
NVYTVRKASAGLAAYIGANGGEAKKRGVVIAYDSRHKSPEFAMEAAKTLAENGVQTYVFD
EEEEEEECCCCEEEEEECCCCCHHHCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEC
ELRPTPELSFAVRELNAFAGIVITASHNPPEYNGYKVYGEDGAQLPPADADKLTGYVNAI
CCCCCCCHHHHHHHHHHHEEEEEEECCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHH
ENELEIEAGDEAALTEKGLIKIIGEEIDQAYLDKLTSISVNPDLAKETEVKVIFTPLHGT
CCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCEEEEEECCCCC
ANKSVRRGLKALGYEHVTVVPEQELPDPDFSTVSSPNPEEHAAFEYAIRLGEENGADILI
CCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHEEECCCCCCEEEE
GTDPDADRLGVAVKDQEGRYVVLTGNQTGALLLHYLLSQKQQKGMLPDNGVVLKTIVTSE
ECCCCHHHCCEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHH
MGRDIAASFGLDTIDTLTGFKFIGEKIKQFEASGEYAFQFGYEESYGYLIGDFARDKDAV
HCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEECHHCCHHHH
QAALLAVEVCAFYKKQGKSLYDGLLELYKSFGFYREGLKSLTLKGKEGAEQIAAILSTFR
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHH
EQPPLSIAGKDVVSAEDYLTGKRTLLKENKRETIDLPKSNVLKYFLEDGSWFCLRPSGTE
CCCCCCCCCCCCCCHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCC
PKVKFYFAVKGRTNEESEALLNQLTDEVMKKIDDIVKATSNS
CCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 2127799 [H]