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The map label for this gene is glpD [H]

Identifier: 52784768

GI number: 52784768

Start: 999034

End: 1000701

Strand: Direct

Name: glpD [H]

Synonym: BLi00996

Alternate gene names: 52784768

Gene position: 999034-1000701 (Clockwise)

Preceding gene: 52784767

Following gene: 52784769

Centisome position: 23.66

GC content: 50.3

Gene sequence:

>1668_bases
ATGGAATCATTATTTTCAAGCCGTAAACGGGACGACATTTTACAGAATATGACAAAGCAGAAGTATGACGTGTTTATTAT
CGGCGGAGGTATTACTGGGGCAGGGACGGCATTGGATGCCGCATCGCGCGGAATGAAAACGGCGCTTTGCGAAATGCAGG
ACTTTGCAGCCGGAACGTCAAGCCGTTCCACGAAACTTGTACACGGCGGGCTTCGCTATTTAAAGCAATTTGAAGTGAAA
ATGGTAGCCGAGGTCGGCAAAGAGCGGGCGATCGTCTATGAAAACGGGCCGCACGTTACAACGCCCGAATGGATGCTGCT
TCCGATGCATAAGGGAGGGACTTTCGGCAAATTCAGCACTTCAATCGGACTGAGGGTGTACGACTTTTTGGCAGGCGTCA
AAAAAGCTGAGCGGAGGAGCATGCTGACTGCCGAAGAAACGCTTCAAAAAGAGCCGCTCGTGAAAAAGAACGGCCTGAAG
GGCGGCGGCTATTATGTCGAATACCGGACGGATGATGCCAGATTGACGATCGAAGTCATGAAAGAAGCCGTTAAATTCGG
AGCCGAGGCCGTCAATTATGCAAAAGTAAGCGATTTTATATATGAAAACGGCAAGGTCACCGGCGTGGTCATTGAAGACG
TCTTCACGAAAAAAACGTACCGCGTCTACGCGAAAAAAATTGTCAATGCCGCGGGGCCGTGGGTCGACCGTCTGCGGGAA
AAAGACCATTCAAAAGAAGGCAAACACCTTCAGCATACAAAAGGCGTGCATCTTGTTTTTGATCAATCGGTCTTTCCTTT
AAAACAAGCCGTTTATTTTGATACGCCTGACGGCCGCATGGTGTTCGCCATTCCGAGAGACGGAAAGGCATATGTCGGCA
CAACAGACACCGTCTACAACGAGAATTTGGAACACCCTCGAATGACGACAGCAGACAGGGATTATGTCATCAATGCAATC
AACTATATGTTCCCTGAACTTGGAATCAAAGCCGAAGATGTCGAATCAAGCTGGGCTGGCCTCAGACCGCTGATTCATGA
AGAAGGAAAAGACCCGTCCGAGATTTCCCGAAAAGATGAGATCTGGACTTCTGAATCCGGACTGATCACGATCGCCGGCG
GAAAGCTGACAGGCTACAGAAAAATGGCTGAGCATATCGTCGATCTTGTCAGAGACCGATTAAAAGAAGAGGGCGACAGA
GACTTCGGGCCTTGCAGAACAAAAACGATGCCGATTTCAGGCGGCCATATCGGCGGCTCCAAAAATCTGGAGGCTTTTAT
TCAAGCGAAAGCAGCCGAAGGGATTGAGGCCGGACTGTCCGAAGAGACGGCCAAACAAATCGCCGCACGATACGGTTCGA
ACGCAGACCGCCTGTTTGATCGTATTCCATCGCTGAAAGATGAAGCAGCAAAACGCCGCATCCCTGTCCATGTACTAGCA
GAAATGGATTACGGGATCGAGGAAGAAATGGCAGCCGTCCCGGCAGACTTCTTCGTCCGCAGAACCGGTGCGCTGTTCTT
TGACATCAATTGGGTCCGCACTTACAAAGAGAGCCTTACGGACTACATGAGCGAGAAGCTGAACTGGGATGGCGAAACGA
AGGCCCGGCATGTCAAGGCATTGGAAGGACTACTACACGATGCTGTTGTCCCGCTGGAAAGCAAATGA

Upstream 100 bases:

>100_bases
GAAGAGGAGAGACCGCAGACACCAAAGCAGTATCAGCGCTTTGGATGTTTGTGGTCTCTTTTTCTATTTTTTACCGTGAC
AACAAGGGAGGACATGAAAC

Downstream 100 bases:

>100_bases
TTTATTAGGTCAAATAACCTTGGTGAATTTTCGTTAATAATCAATCGAATGGCCCGGCGTGAGGCTGTCTTGAACAGGCA
GCCTCATTTTTTTCATTTGG

Product: GlpD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 555; Mature: 555

Protein sequence:

>555_residues
MESLFSSRKRDDILQNMTKQKYDVFIIGGGITGAGTALDAASRGMKTALCEMQDFAAGTSSRSTKLVHGGLRYLKQFEVK
MVAEVGKERAIVYENGPHVTTPEWMLLPMHKGGTFGKFSTSIGLRVYDFLAGVKKAERRSMLTAEETLQKEPLVKKNGLK
GGGYYVEYRTDDARLTIEVMKEAVKFGAEAVNYAKVSDFIYENGKVTGVVIEDVFTKKTYRVYAKKIVNAAGPWVDRLRE
KDHSKEGKHLQHTKGVHLVFDQSVFPLKQAVYFDTPDGRMVFAIPRDGKAYVGTTDTVYNENLEHPRMTTADRDYVINAI
NYMFPELGIKAEDVESSWAGLRPLIHEEGKDPSEISRKDEIWTSESGLITIAGGKLTGYRKMAEHIVDLVRDRLKEEGDR
DFGPCRTKTMPISGGHIGGSKNLEAFIQAKAAEGIEAGLSEETAKQIAARYGSNADRLFDRIPSLKDEAAKRRIPVHVLA
EMDYGIEEEMAAVPADFFVRRTGALFFDINWVRTYKESLTDYMSEKLNWDGETKARHVKALEGLLHDAVVPLESK

Sequences:

>Translated_555_residues
MESLFSSRKRDDILQNMTKQKYDVFIIGGGITGAGTALDAASRGMKTALCEMQDFAAGTSSRSTKLVHGGLRYLKQFEVK
MVAEVGKERAIVYENGPHVTTPEWMLLPMHKGGTFGKFSTSIGLRVYDFLAGVKKAERRSMLTAEETLQKEPLVKKNGLK
GGGYYVEYRTDDARLTIEVMKEAVKFGAEAVNYAKVSDFIYENGKVTGVVIEDVFTKKTYRVYAKKIVNAAGPWVDRLRE
KDHSKEGKHLQHTKGVHLVFDQSVFPLKQAVYFDTPDGRMVFAIPRDGKAYVGTTDTVYNENLEHPRMTTADRDYVINAI
NYMFPELGIKAEDVESSWAGLRPLIHEEGKDPSEISRKDEIWTSESGLITIAGGKLTGYRKMAEHIVDLVRDRLKEEGDR
DFGPCRTKTMPISGGHIGGSKNLEAFIQAKAAEGIEAGLSEETAKQIAARYGSNADRLFDRIPSLKDEAAKRRIPVHVLA
EMDYGIEEEMAAVPADFFVRRTGALFFDINWVRTYKESLTDYMSEKLNWDGETKARHVKALEGLLHDAVVPLESK
>Mature_555_residues
MESLFSSRKRDDILQNMTKQKYDVFIIGGGITGAGTALDAASRGMKTALCEMQDFAAGTSSRSTKLVHGGLRYLKQFEVK
MVAEVGKERAIVYENGPHVTTPEWMLLPMHKGGTFGKFSTSIGLRVYDFLAGVKKAERRSMLTAEETLQKEPLVKKNGLK
GGGYYVEYRTDDARLTIEVMKEAVKFGAEAVNYAKVSDFIYENGKVTGVVIEDVFTKKTYRVYAKKIVNAAGPWVDRLRE
KDHSKEGKHLQHTKGVHLVFDQSVFPLKQAVYFDTPDGRMVFAIPRDGKAYVGTTDTVYNENLEHPRMTTADRDYVINAI
NYMFPELGIKAEDVESSWAGLRPLIHEEGKDPSEISRKDEIWTSESGLITIAGGKLTGYRKMAEHIVDLVRDRLKEEGDR
DFGPCRTKTMPISGGHIGGSKNLEAFIQAKAAEGIEAGLSEETAKQIAARYGSNADRLFDRIPSLKDEAAKRRIPVHVLA
EMDYGIEEEMAAVPADFFVRRTGALFFDINWVRTYKESLTDYMSEKLNWDGETKARHVKALEGLLHDAVVPLESK

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=558, Percent_Identity=32.7956989247312, Blast_Score=276, Evalue=4e-74,
Organism=Homo sapiens, GI285002231, Length=558, Percent_Identity=32.7956989247312, Blast_Score=276, Evalue=4e-74,
Organism=Escherichia coli, GI2367226, Length=500, Percent_Identity=29.6, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI1788574, Length=407, Percent_Identity=26.044226044226, Blast_Score=86, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI115534726, Length=542, Percent_Identity=32.2878228782288, Blast_Score=245, Evalue=4e-65,
Organism=Caenorhabditis elegans, GI17509253, Length=555, Percent_Identity=31.7117117117117, Blast_Score=240, Evalue=1e-63,
Organism=Saccharomyces cerevisiae, GI6322036, Length=588, Percent_Identity=30.952380952381, Blast_Score=236, Evalue=1e-62,
Organism=Drosophila melanogaster, GI161077125, Length=558, Percent_Identity=33.1541218637993, Blast_Score=259, Evalue=3e-69,
Organism=Drosophila melanogaster, GI24653942, Length=558, Percent_Identity=33.1541218637993, Blast_Score=259, Evalue=3e-69,
Organism=Drosophila melanogaster, GI24653944, Length=558, Percent_Identity=33.1541218637993, Blast_Score=259, Evalue=3e-69,
Organism=Drosophila melanogaster, GI20130025, Length=558, Percent_Identity=33.1541218637993, Blast_Score=259, Evalue=3e-69,
Organism=Drosophila melanogaster, GI24586295, Length=559, Percent_Identity=27.1914132379249, Blast_Score=191, Evalue=9e-49,
Organism=Drosophila melanogaster, GI19921278, Length=572, Percent_Identity=27.2727272727273, Blast_Score=168, Evalue=8e-42,
Organism=Drosophila melanogaster, GI45550977, Length=417, Percent_Identity=24.7002398081535, Blast_Score=103, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 62083; Mature: 62083

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESLFSSRKRDDILQNMTKQKYDVFIIGGGITGAGTALDAASRGMKTALCEMQDFAAGTS
CCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCC
SRSTKLVHGGLRYLKQFEVKMVAEVGKERAIVYENGPHVTTPEWMLLPMHKGGTFGKFST
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCEEHH
SIGLRVYDFLAGVKKAERRSMLTAEETLQKEPLVKKNGLKGGGYYVEYRTDDARLTIEVM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCEEEEEECCCCEEHHHHH
KEAVKFGAEAVNYAKVSDFIYENGKVTGVVIEDVFTKKTYRVYAKKIVNAAGPWVDRLRE
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
KDHSKEGKHLQHTKGVHLVFDQSVFPLKQAVYFDTPDGRMVFAIPRDGKAYVGTTDTVYN
HCCCCCCCCHHHCCCEEEEECCCCCCHHHEEEEECCCCEEEEEECCCCCEEECCCHHHCC
ENLEHPRMTTADRDYVINAINYMFPELGIKAEDVESSWAGLRPLIHEEGKDPSEISRKDE
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHCCHHHHHCCCCHHHHHHHHC
IWTSESGLITIAGGKLTGYRKMAEHIVDLVRDRLKEEGDRDFGPCRTKTMPISGGHIGGS
CEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCC
KNLEAFIQAKAAEGIEAGLSEETAKQIAARYGSNADRLFDRIPSLKDEAAKRRIPVHVLA
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHCCCCEEEEE
EMDYGIEEEMAAVPADFFVRRTGALFFDINWVRTYKESLTDYMSEKLNWDGETKARHVKA
ECCCCHHHHHHHCCHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LEGLLHDAVVPLESK
HHHHHHHCCCCCCCC
>Mature Secondary Structure
MESLFSSRKRDDILQNMTKQKYDVFIIGGGITGAGTALDAASRGMKTALCEMQDFAAGTS
CCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCC
SRSTKLVHGGLRYLKQFEVKMVAEVGKERAIVYENGPHVTTPEWMLLPMHKGGTFGKFST
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCEEHH
SIGLRVYDFLAGVKKAERRSMLTAEETLQKEPLVKKNGLKGGGYYVEYRTDDARLTIEVM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCEEEEEECCCCEEHHHHH
KEAVKFGAEAVNYAKVSDFIYENGKVTGVVIEDVFTKKTYRVYAKKIVNAAGPWVDRLRE
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
KDHSKEGKHLQHTKGVHLVFDQSVFPLKQAVYFDTPDGRMVFAIPRDGKAYVGTTDTVYN
HCCCCCCCCHHHCCCEEEEECCCCCCHHHEEEEECCCCEEEEEECCCCCEEECCCHHHCC
ENLEHPRMTTADRDYVINAINYMFPELGIKAEDVESSWAGLRPLIHEEGKDPSEISRKDE
CCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHCCHHHHHCCCCHHHHHHHHC
IWTSESGLITIAGGKLTGYRKMAEHIVDLVRDRLKEEGDRDFGPCRTKTMPISGGHIGGS
CEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCC
KNLEAFIQAKAAEGIEAGLSEETAKQIAARYGSNADRLFDRIPSLKDEAAKRRIPVHVLA
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHCCCCEEEEE
EMDYGIEEEMAAVPADFFVRRTGALFFDINWVRTYKESLTDYMSEKLNWDGETKARHVKA
ECCCCHHHHHHHCCHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LEGLLHDAVVPLESK
HHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2127799; 9579061; 9384377; 1809833 [H]