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The map label for this gene is dppA [H]

Identifier: 52784692

GI number: 52784692

Start: 911538

End: 913136

Strand: Direct

Name: dppA [H]

Synonym: BLi00894

Alternate gene names: 52784692

Gene position: 911538-913136 (Clockwise)

Preceding gene: 52784691

Following gene: 52784693

Centisome position: 21.59

GC content: 46.84

Gene sequence:

>1599_bases
ATGAAAAAGAAAAGCTGGCTGATCTGTTTGGGAATGATTCTGTCTGTTTCCGCTTTTTTAATGGGATGCTCCGGTAACGA
AAGCGGAAAGAACGACGGAGGGACGAACGGCGGAAAAGATACGCTGATCATCGGCAGAGGAGGTGATTCGACATCGCTTG
ATCCGATCACAACGACAGAAGGCGAAGCGTTTAAAGTGACGATCAATATGTTTGAGACCTTGCTGAATTACGGGGAACAA
GACACAACGCTGAAGGAAGGCCTCGCGGTGAAATGGGACGCTTCAGATGACGGTTTGACCTACACATTGGAGCTGAGAAA
AGGCGTGAAATTCCATGATGGAACGGATTTTAATGCAGAAGCCGTCAAATACAATTTTGAGCGGTGGATGAACGGGGATG
AAGAAAAATTTCCTTACTACGGCATGTTCGGAGGCTATAAGAAAGATGAGGGGCACGTCATCAAAGACATAAAAGTTCTC
GACGACCATAAGATTCAGTTCATTTTAAAACGCCCGCAAGCGCCGTTTTTAAAGAACCTTGCCATGACTTCTTTCGGGAT
TGCAAGTCCTGCCGCCATTGAAAAATACGGCGAAAAATTCAGGGAGCACCCCGTCGGCACTGGCCCTTACAAATTTGTCG
AATGGAAGCCGAACGACCGGATCGTCCTTGAGAAAAATGAAGACTATTGGGATCAAGGCAAACCGAAATTGCAGAAGATC
ATTTTCAGAGCCATTCCTGAAAACTCAGCCCGCTTAAATGCATTGAAGACGGGCGAAATCGACCTAATGGATGGCGTCAA
TCCGTCTGATATCGAAAGCATCAAAGCAGACGCCAATCTGAAAATATTTGAAAGGCCTTCAATGAACGTCGGGTATCTCG
GAATGACAACGACGAGAAAGCCATTTGACAATAAGCTGGTCCGCCAGGCGCTGAACCATGCTGTCGATAAACAGGCGATT
ATCGACTCCTTCTACGGAGGTCTCGCTGAATCTGCAAAAAACCCGCTTCCTCCGTCGCTCGAAGGGTACAACGACCAGGT
TAAGGAATATCCGTATGATTTAAAAAAGGCAAAAGAACTCTTAAAAGAAGCCGGCTACCCGGACGGGTTTAAAATGAAGC
TTTGGGCAATGCCGGTACCGCGGCCGTATATGCCGGACGGTATGAAAATAGCCGAAGTGATTCAATCAAGCTTTGAAAAA
ATCGGAGTCAAAGCGGAAATCGTCACTTACGACTGGGCGACGTACTTGGATAAGGTGAGCAAAGGGGAAGCTGATGCGTT
TTTAATGGGCTGGACCGGCGACAACGGAGATCCGGACAACTTCATTTATACGCTGCTTGATAAAGATAATATCGGCGGTA
ACAACTATACGTACTTCAGCAATGATGAGCTTCATGACATCTTAATCGAGGCGCAGTCAGACCCTGATCAAAAGAAAAGA
AATAAACTGTATCAAGATGCGCAGGAGCTCCTCCATGAAGAATCGCCTTGGGTTCCGCTTGTCCATTCCACGCCGATTTT
GGCCGGTTCAAAAGATATCGACGGATATGTTCCGCACCCGACAGGGAGTGAAGTATTGTCCGGCGTAGAGTTTAAATAG

Upstream 100 bases:

>100_bases
TGAAGCGGGCGGACGTCTGCCTTGAAGCGGAGCCGCTTCTTGAAGAGACTGCGGACGGGCATTATGCTGCATGCCATTTT
ACCAATAAGGAGGCTGTACG

Downstream 100 bases:

>100_bases
GTGGTGACAGCCATTGCTTGCGTACTGTTTAAAACGGACGGCCATGCTGATCCCCGTTCTCATCGGCATGACATTGGTCG
TTTTTTCGATCATCCGCTTT

Product: hypothetical protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 532; Mature: 532

Protein sequence:

>532_residues
MKKKSWLICLGMILSVSAFLMGCSGNESGKNDGGTNGGKDTLIIGRGGDSTSLDPITTTEGEAFKVTINMFETLLNYGEQ
DTTLKEGLAVKWDASDDGLTYTLELRKGVKFHDGTDFNAEAVKYNFERWMNGDEEKFPYYGMFGGYKKDEGHVIKDIKVL
DDHKIQFILKRPQAPFLKNLAMTSFGIASPAAIEKYGEKFREHPVGTGPYKFVEWKPNDRIVLEKNEDYWDQGKPKLQKI
IFRAIPENSARLNALKTGEIDLMDGVNPSDIESIKADANLKIFERPSMNVGYLGMTTTRKPFDNKLVRQALNHAVDKQAI
IDSFYGGLAESAKNPLPPSLEGYNDQVKEYPYDLKKAKELLKEAGYPDGFKMKLWAMPVPRPYMPDGMKIAEVIQSSFEK
IGVKAEIVTYDWATYLDKVSKGEADAFLMGWTGDNGDPDNFIYTLLDKDNIGGNNYTYFSNDELHDILIEAQSDPDQKKR
NKLYQDAQELLHEESPWVPLVHSTPILAGSKDIDGYVPHPTGSEVLSGVEFK

Sequences:

>Translated_532_residues
MKKKSWLICLGMILSVSAFLMGCSGNESGKNDGGTNGGKDTLIIGRGGDSTSLDPITTTEGEAFKVTINMFETLLNYGEQ
DTTLKEGLAVKWDASDDGLTYTLELRKGVKFHDGTDFNAEAVKYNFERWMNGDEEKFPYYGMFGGYKKDEGHVIKDIKVL
DDHKIQFILKRPQAPFLKNLAMTSFGIASPAAIEKYGEKFREHPVGTGPYKFVEWKPNDRIVLEKNEDYWDQGKPKLQKI
IFRAIPENSARLNALKTGEIDLMDGVNPSDIESIKADANLKIFERPSMNVGYLGMTTTRKPFDNKLVRQALNHAVDKQAI
IDSFYGGLAESAKNPLPPSLEGYNDQVKEYPYDLKKAKELLKEAGYPDGFKMKLWAMPVPRPYMPDGMKIAEVIQSSFEK
IGVKAEIVTYDWATYLDKVSKGEADAFLMGWTGDNGDPDNFIYTLLDKDNIGGNNYTYFSNDELHDILIEAQSDPDQKKR
NKLYQDAQELLHEESPWVPLVHSTPILAGSKDIDGYVPHPTGSEVLSGVEFK
>Mature_532_residues
MKKKSWLICLGMILSVSAFLMGCSGNESGKNDGGTNGGKDTLIIGRGGDSTSLDPITTTEGEAFKVTINMFETLLNYGEQ
DTTLKEGLAVKWDASDDGLTYTLELRKGVKFHDGTDFNAEAVKYNFERWMNGDEEKFPYYGMFGGYKKDEGHVIKDIKVL
DDHKIQFILKRPQAPFLKNLAMTSFGIASPAAIEKYGEKFREHPVGTGPYKFVEWKPNDRIVLEKNEDYWDQGKPKLQKI
IFRAIPENSARLNALKTGEIDLMDGVNPSDIESIKADANLKIFERPSMNVGYLGMTTTRKPFDNKLVRQALNHAVDKQAI
IDSFYGGLAESAKNPLPPSLEGYNDQVKEYPYDLKKAKELLKEAGYPDGFKMKLWAMPVPRPYMPDGMKIAEVIQSSFEK
IGVKAEIVTYDWATYLDKVSKGEADAFLMGWTGDNGDPDNFIYTLLDKDNIGGNNYTYFSNDELHDILIEAQSDPDQKKR
NKLYQDAQELLHEESPWVPLVHSTPILAGSKDIDGYVPHPTGSEVLSGVEFK

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=548, Percent_Identity=38.5036496350365, Blast_Score=368, Evalue=1e-103,
Organism=Escherichia coli, GI1787052, Length=520, Percent_Identity=32.1153846153846, Blast_Score=283, Evalue=2e-77,
Organism=Escherichia coli, GI1787762, Length=509, Percent_Identity=28.6836935166994, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1787551, Length=503, Percent_Identity=29.6222664015905, Blast_Score=215, Evalue=7e-57,
Organism=Escherichia coli, GI1787495, Length=516, Percent_Identity=26.937984496124, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI1789887, Length=509, Percent_Identity=27.5049115913556, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI87081878, Length=521, Percent_Identity=24.7600767754319, Blast_Score=148, Evalue=8e-37,
Organism=Escherichia coli, GI1789397, Length=493, Percent_Identity=24.5436105476673, Blast_Score=136, Evalue=4e-33,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 59654; Mature: 59654

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKSWLICLGMILSVSAFLMGCSGNESGKNDGGTNGGKDTLIIGRGGDSTSLDPITTTE
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEECCC
GEAFKVTINMFETLLNYGEQDTTLKEGLAVKWDASDDGLTYTLELRKGVKFHDGTDFNAE
CCEEEEEHHHHHHHHHCCCCCCHHHCCCEEEECCCCCCEEEEEEECCCCEECCCCCCCHH
AVKYNFERWMNGDEEKFPYYGMFGGYKKDEGHVIKDIKVLDDHKIQFILKRPQAPFLKNL
HHEEEHHHHCCCCCCCCCEEECCCCCCCCCCCEEEEEEEECCCEEEEEEECCCCHHHHHH
AMTSFGIASPAAIEKYGEKFREHPVGTGPYKFVEWKPNDRIVLEKNEDYWDQGKPKLQKI
HHHHCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCHHHHHH
IFRAIPENSARLNALKTGEIDLMDGVNPSDIESIKADANLKIFERPSMNVGYLGMTTTRK
HHHHCCCCCCEEEEEECCCEEEECCCCHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCC
PFDNKLVRQALNHAVDKQAIIDSFYGGLAESAKNPLPPSLEGYNDQVKEYPYDLKKAKEL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCHHHHHHH
LKEAGYPDGFKMKLWAMPVPRPYMPDGMKIAEVIQSSFEKIGVKAEIVTYDWATYLDKVS
HHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHC
KGEADAFLMGWTGDNGDPDNFIYTLLDKDNIGGNNYTYFSNDELHDILIEAQSDPDQKKR
CCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCEEEECCCCCEEEEEECCCCCCHHHH
NKLYQDAQELLHEESPWVPLVHSTPILAGSKDIDGYVPHPTGSEVLSGVEFK
HHHHHHHHHHHHCCCCCEEEEECCCEECCCCCCCCCCCCCCHHHHHCCCCCC
>Mature Secondary Structure
MKKKSWLICLGMILSVSAFLMGCSGNESGKNDGGTNGGKDTLIIGRGGDSTSLDPITTTE
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEECCC
GEAFKVTINMFETLLNYGEQDTTLKEGLAVKWDASDDGLTYTLELRKGVKFHDGTDFNAE
CCEEEEEHHHHHHHHHCCCCCCHHHCCCEEEECCCCCCEEEEEEECCCCEECCCCCCCHH
AVKYNFERWMNGDEEKFPYYGMFGGYKKDEGHVIKDIKVLDDHKIQFILKRPQAPFLKNL
HHEEEHHHHCCCCCCCCCEEECCCCCCCCCCCEEEEEEEECCCEEEEEEECCCCHHHHHH
AMTSFGIASPAAIEKYGEKFREHPVGTGPYKFVEWKPNDRIVLEKNEDYWDQGKPKLQKI
HHHHCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCHHHHHH
IFRAIPENSARLNALKTGEIDLMDGVNPSDIESIKADANLKIFERPSMNVGYLGMTTTRK
HHHHCCCCCCEEEEEECCCEEEECCCCHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCC
PFDNKLVRQALNHAVDKQAIIDSFYGGLAESAKNPLPPSLEGYNDQVKEYPYDLKKAKEL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCCCCHHHHHHH
LKEAGYPDGFKMKLWAMPVPRPYMPDGMKIAEVIQSSFEKIGVKAEIVTYDWATYLDKVS
HHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHC
KGEADAFLMGWTGDNGDPDNFIYTLLDKDNIGGNNYTYFSNDELHDILIEAQSDPDQKKR
CCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCEEEECCCCCEEEEEECCCCCCHHHH
NKLYQDAQELLHEESPWVPLVHSTPILAGSKDIDGYVPHPTGSEVLSGVEFK
HHHHHHHHHHHHCCCCCEEEEECCCEECCCCCCCCCCCCCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]