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The map label for this gene is acoR [H]

Identifier: 52784651

GI number: 52784651

Start: 872246

End: 874081

Strand: Direct

Name: acoR [H]

Synonym: BLi00853

Alternate gene names: 52784651

Gene position: 872246-874081 (Clockwise)

Preceding gene: 52784650

Following gene: 52784653

Centisome position: 20.66

GC content: 50.22

Gene sequence:

>1836_bases
ATGAATCCGACGCCCTGCTATTTAAATACGTGGAAACGCTTTGTTCAGGAAGGGCTTCTTGATCAGGCCCGCTTGAACAA
AAGAGTCATGGAATCATGGTACCGCTGCAAAAATCGAAATGTCAATCCGTATTTAGATAAAGGACAGTCAATTTTAAAAA
AGGATTTATTCGACGCTCAAAAAAAGAAACACTCGTTATTCCTCGATATCGCCCTGCCTTATCTACACAATATCAGCCGT
GAATTAAAAGAGTCGGAAATGATGGCGCTCCTGATCGATGCCGACGGGTACGTATTAAGCTTGGCCGGCTGCCGGAGGAC
GCTTGAAGAGGCGAAAAAAATCAATTTTGTCGAGGGCGTGCGCTGGACGGAAACAGAAGTCGGCACGAACGCCATCGGAA
CCGCACTTGAAATCGGCGAAGCTGTCACCATTCACGGGACCGAGCATTTTTCGGTCGCTTCCCACCATTGGAGCTGTTCT
GCTGCACCGATTCGCGATGAAGACGGCACCGTTATGGGTTTAATCGATATTTCCTGCCTCACGGATAGAAGGCATCCCTT
TATGCTTGGGATGGCTGCCACTGCCGCACACGCCATCGAACGCGAGATCAGCGCACATACGAAAAAAAACGAAGCCGAGC
TCATCAGCCATTGTCTTGAAAAAATCGATTCGGATCAGCCGTTTATCGTCTGCAATGAAAAAGACAAAATCGTAGCCGCG
AGCAGACCGGTGCGGGAACGTTTTTCCGACTGGAGGAGAATGGATGTCAATGATCTGTATGAGCGCGGGTTTGCCGGGGG
GCACAAGCAGACAATTTTCTCCGCCAAAGACGGGAGGCCCCTCGGTAAGTCGATTGCACTGGCTGAAGTGTCCCGCAATA
AAACAGCTCCATCACTCGTATCCCGTTTCATCTATCCGGGTGAAACAGGAACAAGCCGGGCGTTTCAGCAGGCGCTTCAC
CACATGAGGCTTGCGGCTAAGACGGATGCGAATGTATACATATGGGGGGAAACAGGCTCCGGAAAGGAACTTGCCGCGAG
GGCCATTCATCAGGCGAGCGCACGGAGAAACGGCCCTTTTATCGCCGTCAACTGCGGCGCCATTCCTGAAAGCTTGATGG
AGAGCGAATTGTTCGGCTATGCCGAAGGCGCATTTACAGGAGCAAAGCGCCGCGGTTCAAAAGGGAAGTTTGAACAGGCT
CACCGCGGTACGATTTTTCTCGATGAAATCGGTGAGATCCCTTATCAGATGCAAGTGGCGCTCTTAAGGATCATCGAAGA
GCGGAAGGTCACTCCGATCGGCGGAACCCGTGAAGTTCCCCTCGACATCAGAATCATCACAGCAACACACCGTGATCTGA
AAGACCTTCTCCAAAAAGGAAAGATACGTGAAGATCTGTATTACCGCCTTCATGTTTACCCCGTAAAAATACCGCCGCTC
AGAGAGCGCAAAGAGGACATACCTGATTTGTTCCGCCACTATCAACAACAACACGAGTGGAAGGCCGAGTTTCCGCCGAA
TTTTTTCAAGCGGCTTCAGGAATATCATTGGCCTGGTAACATCCGTGAGCTCTTTAATACATTTGAAAGGCTCAGGGTTT
TATTTCCGGAAGGCGGACTGATCGATCCGTCCCAATACAGCGCGGTGCTGGACGGACTCGATTGGAACAGCGGCGCACCT
TCTGAAGAAGACCGGCTCACATTCAGAGAACGTGTTCAAAAACAAACGATGATGGAAGCTTTGCAAAAAACGAAAGGAAA
TGTGTCCGAAGCGGCCAAGCTGGCCGGAATTCCAAGAAGCACATTTTACAAGCGGCTTCGAAAATATAACCTTTAG

Upstream 100 bases:

>100_bases
AAGGGAGAACTTCGCACAGCGTGAGAGTGCGGAGTTTTTTTTATCGATATTGAAAGCGCTTTTATAATATAATGAGGAAA
AAGCATGAGGAGAGGATGGA

Downstream 100 bases:

>100_bases
CCTCTCGGCGCCCAAAGCATGACGCTGACGCCGGCTAAACAGATCACAGCCCCGGCCCAATCATAGAGGTCGGGGGTTTT
TTTGTCGACCAGCCACCCCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 611; Mature: 611

Protein sequence:

>611_residues
MNPTPCYLNTWKRFVQEGLLDQARLNKRVMESWYRCKNRNVNPYLDKGQSILKKDLFDAQKKKHSLFLDIALPYLHNISR
ELKESEMMALLIDADGYVLSLAGCRRTLEEAKKINFVEGVRWTETEVGTNAIGTALEIGEAVTIHGTEHFSVASHHWSCS
AAPIRDEDGTVMGLIDISCLTDRRHPFMLGMAATAAHAIEREISAHTKKNEAELISHCLEKIDSDQPFIVCNEKDKIVAA
SRPVRERFSDWRRMDVNDLYERGFAGGHKQTIFSAKDGRPLGKSIALAEVSRNKTAPSLVSRFIYPGETGTSRAFQQALH
HMRLAAKTDANVYIWGETGSGKELAARAIHQASARRNGPFIAVNCGAIPESLMESELFGYAEGAFTGAKRRGSKGKFEQA
HRGTIFLDEIGEIPYQMQVALLRIIEERKVTPIGGTREVPLDIRIITATHRDLKDLLQKGKIREDLYYRLHVYPVKIPPL
RERKEDIPDLFRHYQQQHEWKAEFPPNFFKRLQEYHWPGNIRELFNTFERLRVLFPEGGLIDPSQYSAVLDGLDWNSGAP
SEEDRLTFRERVQKQTMMEALQKTKGNVSEAAKLAGIPRSTFYKRLRKYNL

Sequences:

>Translated_611_residues
MNPTPCYLNTWKRFVQEGLLDQARLNKRVMESWYRCKNRNVNPYLDKGQSILKKDLFDAQKKKHSLFLDIALPYLHNISR
ELKESEMMALLIDADGYVLSLAGCRRTLEEAKKINFVEGVRWTETEVGTNAIGTALEIGEAVTIHGTEHFSVASHHWSCS
AAPIRDEDGTVMGLIDISCLTDRRHPFMLGMAATAAHAIEREISAHTKKNEAELISHCLEKIDSDQPFIVCNEKDKIVAA
SRPVRERFSDWRRMDVNDLYERGFAGGHKQTIFSAKDGRPLGKSIALAEVSRNKTAPSLVSRFIYPGETGTSRAFQQALH
HMRLAAKTDANVYIWGETGSGKELAARAIHQASARRNGPFIAVNCGAIPESLMESELFGYAEGAFTGAKRRGSKGKFEQA
HRGTIFLDEIGEIPYQMQVALLRIIEERKVTPIGGTREVPLDIRIITATHRDLKDLLQKGKIREDLYYRLHVYPVKIPPL
RERKEDIPDLFRHYQQQHEWKAEFPPNFFKRLQEYHWPGNIRELFNTFERLRVLFPEGGLIDPSQYSAVLDGLDWNSGAP
SEEDRLTFRERVQKQTMMEALQKTKGNVSEAAKLAGIPRSTFYKRLRKYNL
>Mature_611_residues
MNPTPCYLNTWKRFVQEGLLDQARLNKRVMESWYRCKNRNVNPYLDKGQSILKKDLFDAQKKKHSLFLDIALPYLHNISR
ELKESEMMALLIDADGYVLSLAGCRRTLEEAKKINFVEGVRWTETEVGTNAIGTALEIGEAVTIHGTEHFSVASHHWSCS
AAPIRDEDGTVMGLIDISCLTDRRHPFMLGMAATAAHAIEREISAHTKKNEAELISHCLEKIDSDQPFIVCNEKDKIVAA
SRPVRERFSDWRRMDVNDLYERGFAGGHKQTIFSAKDGRPLGKSIALAEVSRNKTAPSLVSRFIYPGETGTSRAFQQALH
HMRLAAKTDANVYIWGETGSGKELAARAIHQASARRNGPFIAVNCGAIPESLMESELFGYAEGAFTGAKRRGSKGKFEQA
HRGTIFLDEIGEIPYQMQVALLRIIEERKVTPIGGTREVPLDIRIITATHRDLKDLLQKGKIREDLYYRLHVYPVKIPPL
RERKEDIPDLFRHYQQQHEWKAEFPPNFFKRLQEYHWPGNIRELFNTFERLRVLFPEGGLIDPSQYSAVLDGLDWNSGAP
SEEDRLTFRERVQKQTMMEALQKTKGNVSEAAKLAGIPRSTFYKRLRKYNL

Specific function: Acts as a transcriptional activator of the acoABCL operon encoding the acetoin dehydrogenase complex [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788905, Length=298, Percent_Identity=45.3020134228188, Blast_Score=255, Evalue=5e-69,
Organism=Escherichia coli, GI1789233, Length=386, Percent_Identity=38.60103626943, Blast_Score=255, Evalue=6e-69,
Organism=Escherichia coli, GI1790437, Length=307, Percent_Identity=43.6482084690554, Blast_Score=245, Evalue=6e-66,
Organism=Escherichia coli, GI87082117, Length=316, Percent_Identity=40.5063291139241, Blast_Score=241, Evalue=1e-64,
Organism=Escherichia coli, GI1786524, Length=345, Percent_Identity=40.2898550724638, Blast_Score=238, Evalue=1e-63,
Organism=Escherichia coli, GI1788550, Length=296, Percent_Identity=44.2567567567568, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI1789087, Length=310, Percent_Identity=37.4193548387097, Blast_Score=212, Evalue=5e-56,
Organism=Escherichia coli, GI1790299, Length=329, Percent_Identity=37.6899696048632, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI87082152, Length=230, Percent_Identity=43.0434782608696, Blast_Score=194, Evalue=2e-50,
Organism=Escherichia coli, GI87081872, Length=319, Percent_Identity=36.6771159874608, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI1787583, Length=297, Percent_Identity=36.7003367003367, Blast_Score=174, Evalue=2e-44,
Organism=Escherichia coli, GI87081858, Length=305, Percent_Identity=32.7868852459016, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1789828, Length=315, Percent_Identity=31.4285714285714, Blast_Score=137, Evalue=2e-33,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 69655; Mature: 69655

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPTPCYLNTWKRFVQEGLLDQARLNKRVMESWYRCKNRNVNPYLDKGQSILKKDLFDAQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
KKKHSLFLDIALPYLHNISRELKESEMMALLIDADGYVLSLAGCRRTLEEAKKINFVEGV
HHHCCEEEEHHHHHHHHHHHHHHHHCEEEEEEECCCCEEEHHHHHHHHHHHHHCCHHHCC
RWTETEVGTNAIGTALEIGEAVTIHGTEHFSVASHHWSCSAAPIRDEDGTVMGLIDISCL
EECCHHCCCHHHHHHHHHCCEEEEECCCCEEECCCCCCCCCCCCCCCCCCEEEEEEEEEC
TDRRHPFMLGMAATAAHAIEREISAHTKKNEAELISHCLEKIDSDQPFIVCNEKDKIVAA
CCCCCCEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEECCCCCEEEC
SRPVRERFSDWRRMDVNDLYERGFAGGHKQTIFSAKDGRPLGKSIALAEVSRNKTAPSLV
CCCHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHCCCCCHHHH
SRFIYPGETGTSRAFQQALHHMRLAAKTDANVYIWGETGSGKELAARAIHQASARRNGPF
HHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCE
IAVNCGAIPESLMESELFGYAEGAFTGAKRRGSKGKFEQAHRGTIFLDEIGEIPYQMQVA
EEEECCCCCHHHHHHHHHCCCCCCCCCHHHCCCCCCCHHHCCCCEEEHHHCCCCHHHHHH
LLRIIEERKVTPIGGTREVPLDIRIITATHRDLKDLLQKGKIREDLYYRLHVYPVKIPPL
HHHHHHHCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHCCCCCCEEEEEEEEEECCCCH
RERKEDIPDLFRHYQQQHEWKAEFPPNFFKRLQEYHWPGNIRELFNTFERLRVLFPEGGL
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHEEECCCCCC
IDPSQYSAVLDGLDWNSGAPSEEDRLTFRERVQKQTMMEALQKTKGNVSEAAKLAGIPRS
CCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHH
TFYKRLRKYNL
HHHHHHHHCCC
>Mature Secondary Structure
MNPTPCYLNTWKRFVQEGLLDQARLNKRVMESWYRCKNRNVNPYLDKGQSILKKDLFDAQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
KKKHSLFLDIALPYLHNISRELKESEMMALLIDADGYVLSLAGCRRTLEEAKKINFVEGV
HHHCCEEEEHHHHHHHHHHHHHHHHCEEEEEEECCCCEEEHHHHHHHHHHHHHCCHHHCC
RWTETEVGTNAIGTALEIGEAVTIHGTEHFSVASHHWSCSAAPIRDEDGTVMGLIDISCL
EECCHHCCCHHHHHHHHHCCEEEEECCCCEEECCCCCCCCCCCCCCCCCCEEEEEEEEEC
TDRRHPFMLGMAATAAHAIEREISAHTKKNEAELISHCLEKIDSDQPFIVCNEKDKIVAA
CCCCCCEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEECCCCCEEEC
SRPVRERFSDWRRMDVNDLYERGFAGGHKQTIFSAKDGRPLGKSIALAEVSRNKTAPSLV
CCCHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHCCCCCHHHH
SRFIYPGETGTSRAFQQALHHMRLAAKTDANVYIWGETGSGKELAARAIHQASARRNGPF
HHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCE
IAVNCGAIPESLMESELFGYAEGAFTGAKRRGSKGKFEQAHRGTIFLDEIGEIPYQMQVA
EEEECCCCCHHHHHHHHHCCCCCCCCCHHHCCCCCCCHHHCCCCEEEHHHCCCCHHHHHH
LLRIIEERKVTPIGGTREVPLDIRIITATHRDLKDLLQKGKIREDLYYRLHVYPVKIPPL
HHHHHHHCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHCCCCCCEEEEEEEEEECCCCH
RERKEDIPDLFRHYQQQHEWKAEFPPNFFKRLQEYHWPGNIRELFNTFERLRVLFPEGGL
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHEEECCCCCC
IDPSQYSAVLDGLDWNSGAPSEEDRLTFRERVQKQTMMEALQKTKGNVSEAAKLAGIPRS
CCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHH
TFYKRLRKYNL
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377; 10368162 [H]