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The map label for this gene is lpxD [C]

Identifier: 52784598

GI number: 52784598

Start: 810452

End: 811144

Strand: Direct

Name: lpxD [C]

Synonym: BLi00799

Alternate gene names: 52784598

Gene position: 810452-811144 (Clockwise)

Preceding gene: 52784597

Following gene: 52784599

Centisome position: 19.19

GC content: 48.63

Gene sequence:

>693_bases
ATGATTCATGAAACTGCAAAGATCGGAAAGAACGTGGTATTGGGAGAGCATGCCGTTATTGAAGAAAATGTGGTCATCGG
GGACAACGTAACAATCGGTCATCATGCCATTATTAAAAAGGACACTCATATCGGCAGCGGGGTGAAAATCGGCGATTTGG
CCGTCCTTGGCAAAGCGGCTTCTTCAAATAAAAAAATGGCTCGCCAGCCGAAGCAGGCAGGAGCCCCTTTGCGGATAGAA
GATGATGCCATAGTTGGAGCAAGCGCTGTGATTTACCGAGACGTGCTGTTGGAACAAGGCGTCTTCGTGGGGGATATGGC
GAGCATTCGCGAAAATGTCGCGATCGGCAGAGAAAGCATTATAGGACGCAATGCGATGGTTGAAAACAATACCAGAATTG
GAAGTAAAGCAACAATTCAAACGGGCTGCTATATCACTGCTGATATGACGATTGAGGATGAAGTGTTTATCGGTCCCTGC
TGTTCCACGTCAAATGATAAATATATGGGAAAGGGAAACTACCCGTATCAAGGTCCAACTATTAAAAGAGGAGCGAAAAT
CGGGAATAACGCAACATTGCTGCCGGCGGTTGTCGTCGGGGAGGGGGCGGTCATTGGAGCGGGTGCCGTCATTACAAAAG
ATGTTCCCGCAGGCAAAACGGCTGTGGGCAATCCAGGCCGGTTGATGAAGTGA

Upstream 100 bases:

>100_bases
TCGCCTGACGGCGGCCGTGTTTTTTTATGAAGCCGTTTCTCATTACGTCCGCATTGAATATGCTACAGCAGGTGTAAATG
AGAAATGGAGGATGTAAGCA

Downstream 100 bases:

>100_bases
CGGTTTTTCATCTCAGCCGTGTTATATAACGTGTCTGCATAAAAAGAGAGATCATAGGATATAGTGCTTCAATGTCTTTT
AAAGATCATTGCAGGCGGAA

Product: hypothetical protein

Products: UDP-2,3-Bis(3-Hydroxytetradecanoyl)Glucosamine; [Acyl-Carrier Protein]. [C]

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MIHETAKIGKNVVLGEHAVIEENVVIGDNVTIGHHAIIKKDTHIGSGVKIGDLAVLGKAASSNKKMARQPKQAGAPLRIE
DDAIVGASAVIYRDVLLEQGVFVGDMASIRENVAIGRESIIGRNAMVENNTRIGSKATIQTGCYITADMTIEDEVFIGPC
CSTSNDKYMGKGNYPYQGPTIKRGAKIGNNATLLPAVVVGEGAVIGAGAVITKDVPAGKTAVGNPGRLMK

Sequences:

>Translated_230_residues
MIHETAKIGKNVVLGEHAVIEENVVIGDNVTIGHHAIIKKDTHIGSGVKIGDLAVLGKAASSNKKMARQPKQAGAPLRIE
DDAIVGASAVIYRDVLLEQGVFVGDMASIRENVAIGRESIIGRNAMVENNTRIGSKATIQTGCYITADMTIEDEVFIGPC
CSTSNDKYMGKGNYPYQGPTIKRGAKIGNNATLLPAVVVGEGAVIGAGAVITKDVPAGKTAVGNPGRLMK
>Mature_230_residues
MIHETAKIGKNVVLGEHAVIEENVVIGDNVTIGHHAIIKKDTHIGSGVKIGDLAVLGKAASSNKKMARQPKQAGAPLRIE
DDAIVGASAVIYRDVLLEQGVFVGDMASIRENVAIGRESIIGRNAMVENNTRIGSKATIQTGCYITADMTIEDEVFIGPC
CSTSNDKYMGKGNYPYQGPTIKRGAKIGNNATLLPAVVVGEGAVIGAGAVITKDVPAGKTAVGNPGRLMK

Specific function: Lipid A biosynthesis; third step. [C]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 24000; Mature: 24000

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHETAKIGKNVVLGEHAVIEENVVIGDNVTIGHHAIIKKDTHIGSGVKIGDLAVLGKAA
CCCCCHHCCCEEEECCCEEEECCEEECCCEEECCEEEEEECCCCCCCCEECCEEEEECCC
SSNKKMARQPKQAGAPLRIEDDAIVGASAVIYRDVLLEQGVFVGDMASIRENVAIGRESI
CCCCHHHHCHHHCCCCEEECCCCEECHHHHHHHHHHHHCCCEECCHHHHHHHHHCCHHHH
IGRNAMVENNTRIGSKATIQTGCYITADMTIEDEVFIGPCCSTSNDKYMGKGNYPYQGPT
CCCCEEEECCCCCCCCEEEEECEEEEECCEECCCEEEECCCCCCCCCEEECCCCCCCCCC
IKRGAKIGNNATLLPAVVVGEGAVIGAGAVITKDVPAGKTAVGNPGRLMK
CCCCCCCCCCCEEEEEEEECCCEEEECCEEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIHETAKIGKNVVLGEHAVIEENVVIGDNVTIGHHAIIKKDTHIGSGVKIGDLAVLGKAA
CCCCCHHCCCEEEECCCEEEECCEEECCCEEECCEEEEEECCCCCCCCEECCEEEEECCC
SSNKKMARQPKQAGAPLRIEDDAIVGASAVIYRDVLLEQGVFVGDMASIRENVAIGRESI
CCCCHHHHCHHHCCCCEEECCCCEECHHHHHHHHHHHHCCCEECCHHHHHHHHHCCHHHH
IGRNAMVENNTRIGSKATIQTGCYITADMTIEDEVFIGPCCSTSNDKYMGKGNYPYQGPT
CCCCEEEECCCCCCCCEEEEECEEEEECCEECCCEEEECCCCCCCCCEEECCCCCCCCCC
IKRGAKIGNNATLLPAVVVGEGAVIGAGAVITKDVPAGKTAVGNPGRLMK
CCCCCCCCCCCEEEEEEEECCCEEEECCEEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-3-O-(3-Hydroxytetradecanoyl)Glucosamine; (R)-3-Hydroxytetradecanoyl-[Acyl-Carrier Protein] [C]

Specific reaction: UDP-3-O-(3-Hydroxytetradecanoyl)Glucosamine + (R)-3-Hydroxytetradecanoyl-[Acyl-Carrier Protein] = UDP-2,3-Bis(3-Hydroxytetradecanoyl)Glucosamine + [Acyl-Carrier Protein]. [C]

General reaction: Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10708580 [H]