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The map label for this gene is treR [H]

Identifier: 52784597

GI number: 52784597

Start: 809629

End: 810345

Strand: Direct

Name: treR [H]

Synonym: BLi00798

Alternate gene names: 52784597

Gene position: 809629-810345 (Clockwise)

Preceding gene: 52784596

Following gene: 52784598

Centisome position: 19.17

GC content: 46.16

Gene sequence:

>717_bases
ATGAAGATCAACAAGTATATGATGATTTACAAACAAATCGCGGAACAAATCGATCAAAGCATACTGAATGCCGGAGATAT
CCTGCCGTCTGAAAACGACCTTGCCGAACAGCACGACACCTCGAGGGAAACCGTTCGGAAAGCGCTGAACGTGCTTGCTC
AGAACGGATATATTCAGAAGATTAAAGGGAAGGGGTCAGTCGTGCTGCACAGGGAGAAAATGCAGTTCCCGGTTTCCGGT
TTGGTCAGCTTTAAGGAGCTTTCAGAAACGCTCGGAAAAGAGACAAGCACGACGGTCCATGAGTTCGGCTTGACGCATCC
GGACGCATATATTCAAAAGCAGCTCCGCACTTCCGGAGATGAAGAGGTATGGCGGGTTGTCAGGTCGCGGAACATCAACG
GAGAGCGTATCATCCTGGATAAAGACTATTTTATCCGCAAACACGTGCCGCTTTTAACGAAAGAAATATGCGAGGACTCG
ATCTATCAATACCTTGAAGATGAATGCGGGCTCGTCATCAGCTATGCTCATAAGGAAATTGTAGTCGAGCCATGTACGGC
AGAGGATCAAGAGTATTTGGATCTGAACGGATACGAGCACATTGTGGTCGTGAAAAATTTCGTTTTTCTTGATGATACGA
CCTTGTTTCAATATACGGAAAGCAGACACCGCCTTGATAAATTCCGGTTTGTCGATTTTGCAAGAAGAGAAAAGTAG

Upstream 100 bases:

>100_bases
CGATCTTCCCGAGTCATTTAAACGCTTCACAGTGAAACCATATCAATCGATTGTTTATCATCTTGCCAAACCATGCTAAA
CTAAGCGTGGTGGTAAAAAA

Downstream 100 bases:

>100_bases
CACGGTTCGCCTGACGGCGGCCGTGTTTTTTTATGAAGCCGTTTCTCATTACGTCCGCATTGAATATGCTACAGCAGGTG
TAAATGAGAAATGGAGGATG

Product: TreR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MKINKYMMIYKQIAEQIDQSILNAGDILPSENDLAEQHDTSRETVRKALNVLAQNGYIQKIKGKGSVVLHREKMQFPVSG
LVSFKELSETLGKETSTTVHEFGLTHPDAYIQKQLRTSGDEEVWRVVRSRNINGERIILDKDYFIRKHVPLLTKEICEDS
IYQYLEDECGLVISYAHKEIVVEPCTAEDQEYLDLNGYEHIVVVKNFVFLDDTTLFQYTESRHRLDKFRFVDFARREK

Sequences:

>Translated_238_residues
MKINKYMMIYKQIAEQIDQSILNAGDILPSENDLAEQHDTSRETVRKALNVLAQNGYIQKIKGKGSVVLHREKMQFPVSG
LVSFKELSETLGKETSTTVHEFGLTHPDAYIQKQLRTSGDEEVWRVVRSRNINGERIILDKDYFIRKHVPLLTKEICEDS
IYQYLEDECGLVISYAHKEIVVEPCTAEDQEYLDLNGYEHIVVVKNFVFLDDTTLFQYTESRHRLDKFRFVDFARREK
>Mature_238_residues
MKINKYMMIYKQIAEQIDQSILNAGDILPSENDLAEQHDTSRETVRKALNVLAQNGYIQKIKGKGSVVLHREKMQFPVSG
LVSFKELSETLGKETSTTVHEFGLTHPDAYIQKQLRTSGDEEVWRVVRSRNINGERIILDKDYFIRKHVPLLTKEICEDS
IYQYLEDECGLVISYAHKEIVVEPCTAEDQEYLDLNGYEHIVVVKNFVFLDDTTLFQYTESRHRLDKFRFVDFARREK

Specific function: Repressor for the trehalose operon (treP and treA). Binds trehalose-6-phosphate, which probably acts as an inducer [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=233, Percent_Identity=28.3261802575107, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790118, Length=171, Percent_Identity=30.4093567251462, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790540, Length=232, Percent_Identity=21.551724137931, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082252, Length=205, Percent_Identity=23.4146341463415, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR012770
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27768; Mature: 27768

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKINKYMMIYKQIAEQIDQSILNAGDILPSENDLAEQHDTSRETVRKALNVLAQNGYIQK
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCEEE
IKGKGSVVLHREKMQFPVSGLVSFKELSETLGKETSTTVHEFGLTHPDAYIQKQLRTSGD
ECCCCCEEEEHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHCCCH
EEVWRVVRSRNINGERIILDKDYFIRKHVPLLTKEICEDSIYQYLEDECGLVISYAHKEI
HHHHHHHHHCCCCCCEEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCEE
VVEPCTAEDQEYLDLNGYEHIVVVKNFVFLDDTTLFQYTESRHRLDKFRFVDFARREK
EEECCCCCCCCEEECCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKINKYMMIYKQIAEQIDQSILNAGDILPSENDLAEQHDTSRETVRKALNVLAQNGYIQK
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCEEE
IKGKGSVVLHREKMQFPVSGLVSFKELSETLGKETSTTVHEFGLTHPDAYIQKQLRTSGD
ECCCCCEEEEHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHCCCH
EEVWRVVRSRNINGERIILDKDYFIRKHVPLLTKEICEDSIYQYLEDECGLVISYAHKEI
HHHHHHHHHCCCCCCEEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCEE
VVEPCTAEDQEYLDLNGYEHIVVVKNFVFLDDTTLFQYTESRHRLDKFRFVDFARREK
EEECCCCCCCCEEECCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8917076; 8969503; 9384377; 7651129; 8755887 [H]