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The map label for this gene is ycnD [H]

Identifier: 52784290

GI number: 52784290

Start: 473197

End: 473934

Strand: Reverse

Name: ycnD [H]

Synonym: BLi00470

Alternate gene names: 52784290

Gene position: 473934-473197 (Counterclockwise)

Preceding gene: 52784291

Following gene: 52784289

Centisome position: 11.22

GC content: 52.17

Gene sequence:

>738_bases
ATGAATGAAGTATTGAAAACATTGAAAGACCATAGATCAATCCGCAGCTATACAGATGAGCCCGTGAGCCCTGAACAGCT
GGACGACATTATTCAAGCCGTTCAAGCCGCGCCGAATTCCATTAACGGCCAGCAGGTCACCGTGATTACGGTTCAGGATG
AGGAACGGAAAAAGAAAATTGCCGAACTGGCCGGCGGACAGGTCTGGATCGAGCAGGCCCCTGTTTTCCTTTTGTTCTGC
GCGGACTTCAACCGTGCGAAAATCGCCCTTGAGAAAAACGGCGAAACGCTTGCGATCACAGACGGAATGGAATCCGTGCT
TGTCGGAGCTGTCGACGCAGGCATCGCCCTCGGGACGGCCACAGCAGCCGCTGAATCGATGGGACTTGGCACTGTGCCGA
TCGGCGCGGTCCGCGGCCGTGCAGAAGAGTTGATCAAACTGCTCAATATTCCTGAATACGTCTTCCCTGTCGCAGGACTT
GTCGTCGGCCATCCGGCGGACCGCTCCGCCAAAAAGCCGCGCCTCCCGGAACAAGCGGTAAGGCACAGCGAAACGTATCA
ACCGGATTTAAAACCGCTGATCGACGCGTACGATGAAGAAATATCCGAATACATGACAAAACGGACTAACGGACAGGAAA
CAAGAAACTGGTCTCAGGGCATATCCGCTTATTACAATAAAGTGTACTATCCTCACATCCGTGAAATGCTTGAGAAACAA
GGATTTAAACTCGAATAG

Upstream 100 bases:

>100_bases
GCATTTTCAAGCTTTCGTTCAAGCGGCGGGCGACCTTTTATCAGAACCCCTGAATGTGGTTAAAACGCACACAACGGATT
AAAGAAAGGATGAGTTTCTA

Downstream 100 bases:

>100_bases
ATGCTTTAGGCTATCGGTGATCGATAGCCTTTTTCCATGCGTTCCATTCCACATTTCGATGAGCATCGAAGGTCTTTACA
TTTACACTATGTAAAAAAGG

Product: YcnD

Products: NA

Alternate protein names: NAD(P)H-dependent FMN reductase; NAD(P)H-dependent nitroreductase; NAD(P)H-dependent oxidoreductase [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MNEVLKTLKDHRSIRSYTDEPVSPEQLDDIIQAVQAAPNSINGQQVTVITVQDEERKKKIAELAGGQVWIEQAPVFLLFC
ADFNRAKIALEKNGETLAITDGMESVLVGAVDAGIALGTATAAAESMGLGTVPIGAVRGRAEELIKLLNIPEYVFPVAGL
VVGHPADRSAKKPRLPEQAVRHSETYQPDLKPLIDAYDEEISEYMTKRTNGQETRNWSQGISAYYNKVYYPHIREMLEKQ
GFKLE

Sequences:

>Translated_245_residues
MNEVLKTLKDHRSIRSYTDEPVSPEQLDDIIQAVQAAPNSINGQQVTVITVQDEERKKKIAELAGGQVWIEQAPVFLLFC
ADFNRAKIALEKNGETLAITDGMESVLVGAVDAGIALGTATAAAESMGLGTVPIGAVRGRAEELIKLLNIPEYVFPVAGL
VVGHPADRSAKKPRLPEQAVRHSETYQPDLKPLIDAYDEEISEYMTKRTNGQETRNWSQGISAYYNKVYYPHIREMLEKQ
GFKLE
>Mature_245_residues
MNEVLKTLKDHRSIRSYTDEPVSPEQLDDIIQAVQAAPNSINGQQVTVITVQDEERKKKIAELAGGQVWIEQAPVFLLFC
ADFNRAKIALEKNGETLAITDGMESVLVGAVDAGIALGTATAAAESMGLGTVPIGAVRGRAEELIKLLNIPEYVFPVAGL
VVGHPADRSAKKPRLPEQAVRHSETYQPDLKPLIDAYDEEISEYMTKRTNGQETRNWSQGISAYYNKVYYPHIREMLEKQ
GFKLE

Specific function: Reduces FMNH(2) to FMN, with NADPH as reductant. It also reduces nitroaromatic compounds, quinones, chromates and azo dyes. It could supply the reduced form of FMN to luciferase-like protein and contribute to the degradation of aromatic compounds [H]

COG id: COG0778

COG function: function code C; Nitroreductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the flavin oxidoreductase frp family [H]

Homologues:

Organism=Escherichia coli, GI1787075, Length=242, Percent_Identity=37.603305785124, Blast_Score=158, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016446
- InterPro:   IPR000415 [H]

Pfam domain/function: PF00881 Nitroreductase [H]

EC number: =1.5.1.29 [H]

Molecular weight: Translated: 27095; Mature: 27095

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEVLKTLKDHRSIRSYTDEPVSPEQLDDIIQAVQAAPNSINGQQVTVITVQDEERKKKI
CHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHH
AELAGGQVWIEQAPVFLLFCADFNRAKIALEKNGETLAITDGMESVLVGAVDAGIALGTA
HHHCCCEEEEECCCEEEEEECCCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHH
TAAAESMGLGTVPIGAVRGRAEELIKLLNIPEYVFPVAGLVVGHPADRSAKKPRLPEQAV
HHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
RHSETYQPDLKPLIDAYDEEISEYMTKRTNGQETRNWSQGISAYYNKVYYPHIREMLEKQ
HCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHC
GFKLE
CCCCC
>Mature Secondary Structure
MNEVLKTLKDHRSIRSYTDEPVSPEQLDDIIQAVQAAPNSINGQQVTVITVQDEERKKKI
CHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHH
AELAGGQVWIEQAPVFLLFCADFNRAKIALEKNGETLAITDGMESVLVGAVDAGIALGTA
HHHCCCEEEEECCCEEEEEECCCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHH
TAAAESMGLGTVPIGAVRGRAEELIKLLNIPEYVFPVAGLVVGHPADRSAKKPRLPEQAV
HHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
RHSETYQPDLKPLIDAYDEEISEYMTKRTNGQETRNWSQGISAYYNKVYYPHIREMLEKQ
HCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHC
GFKLE
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]