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The map label for this gene is ytlI [H]

Identifier: 52784140

GI number: 52784140

Start: 289305

End: 290189

Strand: Reverse

Name: ytlI [H]

Synonym: BLi00317

Alternate gene names: 52784140

Gene position: 290189-289305 (Counterclockwise)

Preceding gene: 52784144

Following gene: 52784133

Centisome position: 6.87

GC content: 49.94

Gene sequence:

>885_bases
ATGGATTTCAAAACGTTAAAGACGTTTCATAAAATCGTGGCTTGCGGAAGCTTTAACCGCGCGGCTGAAGAACTGAATTA
TGCGCAGTCCACGGTCACAATGCAAATCAAAAAGCTCGAGGAAGACCTCGGCATTCGTTTGCTCGAGAGGGGGAAAACAT
TCCGTCTGACTGAAGCCGGCAGGCTTTTTTTTGAAGAAAGCAGACATATTGTCAAGGATATAGATCACCTTCAACATCAT
ATGGCCGACTTATTGCTTGGCGAAGGGGGAAATATCCGCCTTGGAGCGGTCGAACCGATCGCGAGCTGTGAATTGCCCCA
GATTTTGGGGAGATTTTTAGCGGATTATCCGAAGATCCGGGTTTCCGTTGATATCGCCAACTCGTCGGCATTGGGGGAAC
GGCTGGTTCAAGGAAGCCTGGATCTTGCCGTCTGTTCGACTCCGGCAATGGGAACAGATCTTTATTTTGAACCGCTTTAT
GCTGAAGAACTCGTAGTGCTGCTCCCTGAGGGACACCCCGCCGGAAACAATGAACGCATTCATCTGAAAGATATTAGGGA
GCACCGCCTGCTGATTACGGCCAACAATTGCACCTACCGGAAGAAAGTCGAAATCGCGTTTCAAGAGCTGCCGGGGAGCC
AAATGAACACGATGGAGATCGGAAGCATGACAGCTTTGAAAAACTATGTTGCCGCAGGACTCGGCGTTGCCCTGATTCCG
AAAAGCATCGTTTCCCCTCCTCCTCCCGGAACGATTGTCCGGTTTATCGACGATGACCCGATCAGCGTAACCTTCGGCAT
CCTTTGCAAAACCGCGGCGTTTCCGCTGAAACAGGCTGATGCAAAGCTGTACCAATATTTGAAACAGGAACTTGGAGAAC
CGTAA

Upstream 100 bases:

>100_bases
CCTCCTTTGTATTGTTTAATAGTGTATAACGGTTATATCATTTTGTATAATTGAATCATTTGAAGGTTTCATTCAATTTT
ATTGAACTTGAGGTGATGGG

Downstream 100 bases:

>100_bases
AAAACCTTCCCGGCCGATGCCGGAAGGTTTTTGATTATGAGAATGACGAGATATGGAAATGATGATCTGGTCTCAGAGGG
GGATGGTCACTTGTACCTGT

Product: YtlI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MDFKTLKTFHKIVACGSFNRAAEELNYAQSTVTMQIKKLEEDLGIRLLERGKTFRLTEAGRLFFEESRHIVKDIDHLQHH
MADLLLGEGGNIRLGAVEPIASCELPQILGRFLADYPKIRVSVDIANSSALGERLVQGSLDLAVCSTPAMGTDLYFEPLY
AEELVVLLPEGHPAGNNERIHLKDIREHRLLITANNCTYRKKVEIAFQELPGSQMNTMEIGSMTALKNYVAAGLGVALIP
KSIVSPPPPGTIVRFIDDDPISVTFGILCKTAAFPLKQADAKLYQYLKQELGEP

Sequences:

>Translated_294_residues
MDFKTLKTFHKIVACGSFNRAAEELNYAQSTVTMQIKKLEEDLGIRLLERGKTFRLTEAGRLFFEESRHIVKDIDHLQHH
MADLLLGEGGNIRLGAVEPIASCELPQILGRFLADYPKIRVSVDIANSSALGERLVQGSLDLAVCSTPAMGTDLYFEPLY
AEELVVLLPEGHPAGNNERIHLKDIREHRLLITANNCTYRKKVEIAFQELPGSQMNTMEIGSMTALKNYVAAGLGVALIP
KSIVSPPPPGTIVRFIDDDPISVTFGILCKTAAFPLKQADAKLYQYLKQELGEP
>Mature_294_residues
MDFKTLKTFHKIVACGSFNRAAEELNYAQSTVTMQIKKLEEDLGIRLLERGKTFRLTEAGRLFFEESRHIVKDIDHLQHH
MADLLLGEGGNIRLGAVEPIASCELPQILGRFLADYPKIRVSVDIANSSALGERLVQGSLDLAVCSTPAMGTDLYFEPLY
AEELVVLLPEGHPAGNNERIHLKDIREHRLLITANNCTYRKKVEIAFQELPGSQMNTMEIGSMTALKNYVAAGLGVALIP
KSIVSPPPPGTIVRFIDDDPISVTFGILCKTAAFPLKQADAKLYQYLKQELGEP

Specific function: Positively regulates the expression of ytmI operon in response to the availability of sulfur sources [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787806, Length=252, Percent_Identity=28.5714285714286, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1790399, Length=249, Percent_Identity=26.1044176706827, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI145693105, Length=274, Percent_Identity=24.4525547445255, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1787879, Length=247, Percent_Identity=26.7206477732794, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1788481, Length=246, Percent_Identity=24.390243902439, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI157672245, Length=249, Percent_Identity=23.6947791164659, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1790208, Length=256, Percent_Identity=28.515625, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788297, Length=246, Percent_Identity=27.2357723577236, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87082132, Length=249, Percent_Identity=26.9076305220884, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI2367136, Length=258, Percent_Identity=25.1937984496124, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789204, Length=293, Percent_Identity=23.5494880546075, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1788887, Length=244, Percent_Identity=26.2295081967213, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1787530, Length=236, Percent_Identity=22.0338983050847, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790262, Length=247, Percent_Identity=26.3157894736842, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788748, Length=251, Percent_Identity=24.7011952191235, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787601, Length=285, Percent_Identity=23.5087719298246, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1789506, Length=244, Percent_Identity=23.3606557377049, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789639, Length=122, Percent_Identity=27.8688524590164, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87081904, Length=212, Percent_Identity=26.8867924528302, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1786401, Length=156, Percent_Identity=28.2051282051282, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788296, Length=246, Percent_Identity=24.390243902439, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32560; Mature: 32560

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFKTLKTFHKIVACGSFNRAAEELNYAQSTVTMQIKKLEEDLGIRLLERGKTFRLTEAG
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCEEEEEHHH
RLFFEESRHIVKDIDHLQHHMADLLLGEGGNIRLGAVEPIASCELPQILGRFLADYPKIR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHCCCHHHHHHHHHCCCCEEE
VSVDIANSSALGERLVQGSLDLAVCSTPAMGTDLYFEPLYAEELVVLLPEGHPAGNNERI
EEEEECCCHHHHHHHHHCCCCEEEECCCCCCCCCEECCCCCCCEEEEEECCCCCCCCCEE
HLKDIREHRLLITANNCTYRKKVEIAFQELPGSQMNTMEIGSMTALKNYVAAGLGVALIP
EEEECCCCEEEEEECCCCEEHHHEEHHHHCCCCCCCEEEHHHHHHHHHHHHHCCCHHHCC
KSIVSPPPPGTIVRFIDDDPISVTFGILCKTAAFPLKQADAKLYQYLKQELGEP
HHHCCCCCCCCEEEEECCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDFKTLKTFHKIVACGSFNRAAEELNYAQSTVTMQIKKLEEDLGIRLLERGKTFRLTEAG
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCEEEEEHHH
RLFFEESRHIVKDIDHLQHHMADLLLGEGGNIRLGAVEPIASCELPQILGRFLADYPKIR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHCCCHHHHHHHHHCCCCEEE
VSVDIANSSALGERLVQGSLDLAVCSTPAMGTDLYFEPLYAEELVVLLPEGHPAGNNERI
EEEEECCCHHHHHHHHHCCCCEEEECCCCCCCCCEECCCCCCCEEEEEECCCCCCCCCEE
HLKDIREHRLLITANNCTYRKKVEIAFQELPGSQMNTMEIGSMTALKNYVAAGLGVALIP
EEEECCCCEEEEEECCCCEEHHHEEHHHHCCCCCCCEEEHHHHHHHHHHHHHCCCHHHCC
KSIVSPPPPGTIVRFIDDDPISVTFGILCKTAAFPLKQADAKLYQYLKQELGEP
HHHCCCCCCCCEEEEECCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]