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The map label for this gene is clpC [H]

Identifier: 52783942

GI number: 52783942

Start: 102347

End: 104779

Strand: Direct

Name: clpC [H]

Synonym: BLi00104

Alternate gene names: 52783942

Gene position: 102347-104779 (Clockwise)

Preceding gene: 52783941

Following gene: 52783943

Centisome position: 2.42

GC content: 48.13

Gene sequence:

>2433_bases
ATGATGTTTGGAAGATTCACAGAAAGAGCACAAAAAGTATTGGCGCTTGCTCAAGAAGAAGCTCTGCGTCTGGGCCATAA
TAACATTGGAACAGAACATATTCTCCTCGGCCTTGTCCGCGAGGGAGAAGGAATTGCTGCGAAAGCGCTGCAGGCGTTAG
GACTCAGCCCTGACAAGATTCAAAAAGAAGTTGAAAGCCTCATCGGCCGCGGACAAGAAATGTCACAATCGATCCATTAC
ACACCGAGAGCCAAGAAAGTGACCGAATTGGCGATGGATGAAGCGAGAAAGCTTGGCCACTCCTACGTTGGAACTGAACA
CATCCTCCTTGGCTTAATCCGCGAAGGGGAAGGTGTTGCGGCAAGGGTGCTGAATAATTTAGGCGTCAGCTTAAACAAAG
CGAGACAGCAAGTATTGCAGCTGTTGGGCAGCAATGAGAGCGGAGGCGCTGCTTCAGGCGCCAACAGTAGCGCCAACACA
CCAACTTTAGACAGTCTTGCCCGGGATCTCACGGCGATTGCAAAAGAAGACAGCCTTGATCCCGTGATCGGCAGAAGCAA
AGAAATTCAACGCGTGATTGAAGTGTTGAGCCGCAGAACGAAAAATAACCCTGTGTTAATCGGGGAGCCTGGTGTCGGTA
AGACTGCGATTGCCGAAGGCCTGGCCCAGCAGATCATCAATAACGAAGTACCGGAGATTTTACGCGACAAGCGCGTCATG
ACACTTGATATGGGAACGGTTGTCGCCGGCACGAAATATCGCGGTGAATTTGAAGACCGCCTGAAAAAAGTGATGGACGA
AATTCGTCAAGCGGGAAATATCATCCTCTTCATCGATGAGCTGCATACTCTCATCGGAGCCGGAGGAGCGGAAGGGGCCA
TCGATGCCTCCAATATCCTTAAACCGTCGCTGGCGCGCGGAGAGCTGCAATGCATCGGGGCGACAACCCTTGATGAATAC
CGCAAATACATTGAAAAAGATGCTGCACTAGAACGGCGTTTTCAGCCGATTCAGGTTGACCAGCCGTCTCCTGAAGAAAG
CATTCAAATATTGAAAGGGCTCAGAGACCGCTATGAAGCCCATCACCGCGTATCGATTACGGATGAAGCGATCGAAGCGG
CAGTAAAGCTGTCAGACCGCTACATTTCGGACCGTTTTCTGCCTGACAAGGCGATCGACTTAATCGATGAAGCCGGCTCA
AAGGTTAGACTGCGTTCATTCACAACGCCTCCTAACTTAAAAGAGCTTGAACAAAAGCTTGATGAGGTAAGGAAAGAAAA
AGATGCCGCTGTTCAAAGCCAGGAATTCGAAAAAGCAGCGTCTTTACGTGATACGGAGCAGCGCTTGCGTGAACAGGTCG
AAGAAACCAAGAAAACCTGGAAAGAAAAGCAAGGTCAAGAAAATTCCGAAGTGACCGTCGACGATATTGCAATGGTTGTA
TCAAGCTGGACCGGAGTGCCGGTTTCCAAAATTGCGCAGACCGAAACAGACAAATTGCTGAACATGGAGAGCATTCTTCA
TTCCCGCGTTATCGGCCAGGATGAGGCTGTCGTTGCAGTTGCAAAAGCAGTCAGACGCGCGCGTGCCGGCTTAAAAGATC
CAAAACGTCCTATCGGTTCGTTTATTTTCCTTGGCCCAACAGGCGTAGGGAAAACGGAGCTTGCCCGTGCACTTGCCGAG
TCCATTTTCGGCGATGAAGAAGCAATGATTCGCATCGATATGTCCGAGTACATGGAAAAACATTCAACATCAAGACTCGT
CGGTTCACCTCCTGGATATGTCGGCTATGATGAAGGCGGACAGCTCACTGAAAAAGTGAGAAGAAAACCGTATTCCGTCG
TCTTGCTTGATGAAATCGAGAAAGCTCACCCAGATGTCTTCAATATTTTGCTGCAGGTGCTTGAAGACGGCCGCCTGACT
GATTCAAAAGGGCGCACGGTTGACTTTAGGAATACGATTTTGATCATGACATCAAACGTCGGTGCGAGCGAACTGAGAAG
AAATAAATACGTCGGGTTTAATGTCCAGGATGAAACCCAGAATTATAAAGATATGAAAGACAAAGTCATGGGTGAACTAA
AACGCGCCTTTAGACCTGAATTTATCAACCGGATTGATGAGATCATCGTCTTCCACTCTTTGGAGAAAAAACATTTGAAA
GATATTGTATCCCTCATGTCAGACCAATTGACCAAGCGTCTGAAAGAACAGGATCTTTCAATTGAGCTGACTGAAGCGGC
TAAAGAAAAAATCGCCGATGAAGGCGTGGATCTCGAATACGGAGCGCGTCCTCTCAGAAGAGCAATCCAAAAACACGTGG
AAGACCGGCTGTCAGAAGAGCTCCTAAAAGGCCATATTCAAAAAGGCCAGCATATTGTTTTGGATGTAGAAGACGGAGAA
TTTGTCGTAAAAACCGAAGCTAAAACGAACTAA

Upstream 100 bases:

>100_bases
GAGCCTTAAGGCCAAACGAGAGGGACATCAGGCGGGCTGCTCTTATCAGGGAGCGCTTGAAATTAGAAAACAACGGCAAT
AGACAGGAGGATGAAACGAT

Downstream 100 bases:

>100_bases
TATAGAGACAAAAGAAAGAGGCATACGATGTTCATCAGTATGCCTCACTTTCTTATAAAGGGAGCGTTTTGAAAAATCAA
TGGCTAAAACAAAGACTAAA

Product: ClpC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 810; Mature: 810

Protein sequence:

>810_residues
MMFGRFTERAQKVLALAQEEALRLGHNNIGTEHILLGLVREGEGIAAKALQALGLSPDKIQKEVESLIGRGQEMSQSIHY
TPRAKKVTELAMDEARKLGHSYVGTEHILLGLIREGEGVAARVLNNLGVSLNKARQQVLQLLGSNESGGAASGANSSANT
PTLDSLARDLTAIAKEDSLDPVIGRSKEIQRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQQIINNEVPEILRDKRVM
TLDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNIILFIDELHTLIGAGGAEGAIDASNILKPSLARGELQCIGATTLDEY
RKYIEKDAALERRFQPIQVDQPSPEESIQILKGLRDRYEAHHRVSITDEAIEAAVKLSDRYISDRFLPDKAIDLIDEAGS
KVRLRSFTTPPNLKELEQKLDEVRKEKDAAVQSQEFEKAASLRDTEQRLREQVEETKKTWKEKQGQENSEVTVDDIAMVV
SSWTGVPVSKIAQTETDKLLNMESILHSRVIGQDEAVVAVAKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAE
SIFGDEEAMIRIDMSEYMEKHSTSRLVGSPPGYVGYDEGGQLTEKVRRKPYSVVLLDEIEKAHPDVFNILLQVLEDGRLT
DSKGRTVDFRNTILIMTSNVGASELRRNKYVGFNVQDETQNYKDMKDKVMGELKRAFRPEFINRIDEIIVFHSLEKKHLK
DIVSLMSDQLTKRLKEQDLSIELTEAAKEKIADEGVDLEYGARPLRRAIQKHVEDRLSEELLKGHIQKGQHIVLDVEDGE
FVVKTEAKTN

Sequences:

>Translated_810_residues
MMFGRFTERAQKVLALAQEEALRLGHNNIGTEHILLGLVREGEGIAAKALQALGLSPDKIQKEVESLIGRGQEMSQSIHY
TPRAKKVTELAMDEARKLGHSYVGTEHILLGLIREGEGVAARVLNNLGVSLNKARQQVLQLLGSNESGGAASGANSSANT
PTLDSLARDLTAIAKEDSLDPVIGRSKEIQRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQQIINNEVPEILRDKRVM
TLDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNIILFIDELHTLIGAGGAEGAIDASNILKPSLARGELQCIGATTLDEY
RKYIEKDAALERRFQPIQVDQPSPEESIQILKGLRDRYEAHHRVSITDEAIEAAVKLSDRYISDRFLPDKAIDLIDEAGS
KVRLRSFTTPPNLKELEQKLDEVRKEKDAAVQSQEFEKAASLRDTEQRLREQVEETKKTWKEKQGQENSEVTVDDIAMVV
SSWTGVPVSKIAQTETDKLLNMESILHSRVIGQDEAVVAVAKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAE
SIFGDEEAMIRIDMSEYMEKHSTSRLVGSPPGYVGYDEGGQLTEKVRRKPYSVVLLDEIEKAHPDVFNILLQVLEDGRLT
DSKGRTVDFRNTILIMTSNVGASELRRNKYVGFNVQDETQNYKDMKDKVMGELKRAFRPEFINRIDEIIVFHSLEKKHLK
DIVSLMSDQLTKRLKEQDLSIELTEAAKEKIADEGVDLEYGARPLRRAIQKHVEDRLSEELLKGHIQKGQHIVLDVEDGE
FVVKTEAKTN
>Mature_810_residues
MMFGRFTERAQKVLALAQEEALRLGHNNIGTEHILLGLVREGEGIAAKALQALGLSPDKIQKEVESLIGRGQEMSQSIHY
TPRAKKVTELAMDEARKLGHSYVGTEHILLGLIREGEGVAARVLNNLGVSLNKARQQVLQLLGSNESGGAASGANSSANT
PTLDSLARDLTAIAKEDSLDPVIGRSKEIQRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQQIINNEVPEILRDKRVM
TLDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNIILFIDELHTLIGAGGAEGAIDASNILKPSLARGELQCIGATTLDEY
RKYIEKDAALERRFQPIQVDQPSPEESIQILKGLRDRYEAHHRVSITDEAIEAAVKLSDRYISDRFLPDKAIDLIDEAGS
KVRLRSFTTPPNLKELEQKLDEVRKEKDAAVQSQEFEKAASLRDTEQRLREQVEETKKTWKEKQGQENSEVTVDDIAMVV
SSWTGVPVSKIAQTETDKLLNMESILHSRVIGQDEAVVAVAKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAE
SIFGDEEAMIRIDMSEYMEKHSTSRLVGSPPGYVGYDEGGQLTEKVRRKPYSVVLLDEIEKAHPDVFNILLQVLEDGRLT
DSKGRTVDFRNTILIMTSNVGASELRRNKYVGFNVQDETQNYKDMKDKVMGELKRAFRPEFINRIDEIIVFHSLEKKHLK
DIVSLMSDQLTKRLKEQDLSIELTEAAKEKIADEGVDLEYGARPLRRAIQKHVEDRLSEELLKGHIQKGQHIVLDVEDGE
FVVKTEAKTN

Specific function: Competence gene repressor; required for cell growth at high temperature. Negative regulator of comK expression. May interact with MecA to negatively regulate comK [H]

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=323, Percent_Identity=35.9133126934984, Blast_Score=206, Evalue=5e-53,
Organism=Escherichia coli, GI1788943, Length=870, Percent_Identity=47.5862068965517, Blast_Score=747, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=795, Percent_Identity=39.2452830188679, Blast_Score=545, Evalue=1e-156,
Organism=Saccharomyces cerevisiae, GI6320464, Length=712, Percent_Identity=47.6123595505618, Blast_Score=639, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=378, Percent_Identity=41.5343915343915, Blast_Score=291, Evalue=3e-79,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 90167; Mature: 90167

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS50151 UVR ; PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMFGRFTERAQKVLALAQEEALRLGHNNIGTEHILLGLVREGEGIAAKALQALGLSPDKI
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCHHHH
QKEVESLIGRGQEMSQSIHYTPRAKKVTELAMDEARKLGHSYVGTEHILLGLIREGEGVA
HHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHH
ARVLNNLGVSLNKARQQVLQLLGSNESGGAASGANSSANTPTLDSLARDLTAIAKEDSLD
HHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
PVIGRSKEIQRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQQIINNEVPEILRDKRVM
CCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHCCCEE
TLDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNIILFIDELHTLIGAGGAEGAIDASNIL
EEECCHHEECCCCCCCHHHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCCCCCHHHHC
KPSLARGELQCIGATTLDEYRKYIEKDAALERRFQPIQVDQPSPEESIQILKGLRDRYEA
CCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
HHRVSITDEAIEAAVKLSDRYISDRFLPDKAIDLIDEAGSKVRLRSFTTPPNLKELEQKL
HCCEECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHH
DEVRKEKDAAVQSQEFEKAASLRDTEQRLREQVEETKKTWKEKQGQENSEVTVDDIAMVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
SSWTGVPVSKIAQTETDKLLNMESILHSRVIGQDEAVVAVAKAVRRARAGLKDPKRPIGS
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
FIFLGPTGVGKTELARALAESIFGDEEAMIRIDMSEYMEKHSTSRLVGSPPGYVGYDEGG
EEEECCCCCCHHHHHHHHHHHHCCCCHHEEEECHHHHHHHHCCCCCCCCCCCCCCCCCCC
QLTEKVRRKPYSVVLLDEIEKAHPDVFNILLQVLEDGRLTDSKGRTVDFRNTILIMTSNV
HHHHHHHCCCCEEEEHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEECCEEEEEECCC
GASELRRNKYVGFNVQDETQNYKDMKDKVMGELKRAFRPEFINRIDEIIVFHSLEKKHLK
CHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
DIVSLMSDQLTKRLKEQDLSIELTEAAKEKIADEGVDLEYGARPLRRAIQKHVEDRLSEE
HHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
LLKGHIQKGQHIVLDVEDGEFVVKTEAKTN
HHHHHHCCCCEEEEEECCCCEEEEECCCCC
>Mature Secondary Structure
MMFGRFTERAQKVLALAQEEALRLGHNNIGTEHILLGLVREGEGIAAKALQALGLSPDKI
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCHHHH
QKEVESLIGRGQEMSQSIHYTPRAKKVTELAMDEARKLGHSYVGTEHILLGLIREGEGVA
HHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHH
ARVLNNLGVSLNKARQQVLQLLGSNESGGAASGANSSANTPTLDSLARDLTAIAKEDSLD
HHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
PVIGRSKEIQRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQQIINNEVPEILRDKRVM
CCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHCCCEE
TLDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNIILFIDELHTLIGAGGAEGAIDASNIL
EEECCHHEECCCCCCCHHHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCCCCCHHHHC
KPSLARGELQCIGATTLDEYRKYIEKDAALERRFQPIQVDQPSPEESIQILKGLRDRYEA
CCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
HHRVSITDEAIEAAVKLSDRYISDRFLPDKAIDLIDEAGSKVRLRSFTTPPNLKELEQKL
HCCEECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHH
DEVRKEKDAAVQSQEFEKAASLRDTEQRLREQVEETKKTWKEKQGQENSEVTVDDIAMVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
SSWTGVPVSKIAQTETDKLLNMESILHSRVIGQDEAVVAVAKAVRRARAGLKDPKRPIGS
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
FIFLGPTGVGKTELARALAESIFGDEEAMIRIDMSEYMEKHSTSRLVGSPPGYVGYDEGG
EEEECCCCCCHHHHHHHHHHHHCCCCHHEEEECHHHHHHHHCCCCCCCCCCCCCCCCCCC
QLTEKVRRKPYSVVLLDEIEKAHPDVFNILLQVLEDGRLTDSKGRTVDFRNTILIMTSNV
HHHHHHHCCCCEEEEHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEECCEEEEEECCC
GASELRRNKYVGFNVQDETQNYKDMKDKVMGELKRAFRPEFINRIDEIIVFHSLEKKHLK
CHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
DIVSLMSDQLTKRLKEQDLSIELTEAAKEKIADEGVDLEYGARPLRRAIQKHVEDRLSEE
HHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
LLKGHIQKGQHIVLDVEDGEFVVKTEAKTN
HHHHHHCCCCEEEEEECCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8016066; 7584024; 9384377; 8195092 [H]