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The map label for this gene is hslO

Identifier: 52783928

GI number: 52783928

Start: 84484

End: 85353

Strand: Direct

Name: hslO

Synonym: BLi00087

Alternate gene names: 52783928

Gene position: 84484-85353 (Clockwise)

Preceding gene: 52783927

Following gene: 52783929

Centisome position: 2.0

GC content: 48.39

Gene sequence:

>870_bases
ATGGATTATTTAGTGAAAGCCATTGCATATGACGGCAAAGTGAGGGCATATGCAGCGAATACAACAGAAACGATTCATGA
AGCCCAAAGAAGGCATAACACATGGCCTACCGCTTCCGCCGCTTTAGGAAGAACGATGACGGCGGCTGTCATGCTCGGCG
CCATGCTGAAAGGCGAAGACAAGCTCACCGTTAAGATTGAAGGAGGCGGACCGATCGGCGCGATTGTCGCTGACGGAAAT
GCAAAAGGAGACGTCAGGGGATACGTGTCCAATCCGCACGTTCATTTCGACTTAAATGAACACGGCAAACTTGACGTCAG
AAGAGCCGTCGGTACGTCAGGAACGCTAAGCGTAGTAAAAGATCTCGGTCTCCGCGATTTATTTACAGGCCAGGTTGAGA
TCGTTTCCGGAGAAATCGGCGAGGATTTTACTTATTATCTCGTGTCCTCTGAACAGGTTCCTTCTTCGGTGGGTGTAGGG
GTGCTCGTCAACCCCGACAATACGATTTTAGCTGCAGGCGGATTTATCCTGCAGCTGCTGCCGGGAACGGACGACGAAAC
CATCACGAAGCTTGAAACAAACCTTTCACAAGTGGAGCCAATTTCAAAGCTGATTCAGAAAGGTTTGACACCTGAGGAAG
TGCTGGCTGCGGTATTGGGAGAAGAACCGGAAGTACTGGAAACCGTTCCTGTCCGATTTACATGCAATTGTTCAAAAGAA
CGTTTCGCAAGAGGCATCATCGGTCTTGGCAAGGATGAAATTCAACAGATGATTGATGAAGATGGCCAAGCCGAGGCTCA
ATGCCATTTTTGCAATGAAACGTATCTGTTTACAAAGGAAGAGCTTGAAGCGCTTCGAGATGAAATATAA

Upstream 100 bases:

>100_bases
AATCGGACTGCATCGATATTGTTGACCCGTTCCTTACGTTGAAGGGGCTAGAGCTCATTTATGAACGGAATCGTGTTGAA
AGTGTATAGGAGGATGAGGT

Downstream 100 bases:

>100_bases
GCCCGCTATCCAGTAGCGGGTCTTTTACAATGGGGAAAGGGGAGACACCATATTGAAATCGAGAACACTTTGGCCGATTA
TTTTAGGTGCGATCTTCGTC

Product: Hsp33-like chaperonin

Products: NA

Alternate protein names: Heat shock protein 33 homolog; HSP33

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MDYLVKAIAYDGKVRAYAANTTETIHEAQRRHNTWPTASAALGRTMTAAVMLGAMLKGEDKLTVKIEGGGPIGAIVADGN
AKGDVRGYVSNPHVHFDLNEHGKLDVRRAVGTSGTLSVVKDLGLRDLFTGQVEIVSGEIGEDFTYYLVSSEQVPSSVGVG
VLVNPDNTILAAGGFILQLLPGTDDETITKLETNLSQVEPISKLIQKGLTPEEVLAAVLGEEPEVLETVPVRFTCNCSKE
RFARGIIGLGKDEIQQMIDEDGQAEAQCHFCNETYLFTKEELEALRDEI

Sequences:

>Translated_289_residues
MDYLVKAIAYDGKVRAYAANTTETIHEAQRRHNTWPTASAALGRTMTAAVMLGAMLKGEDKLTVKIEGGGPIGAIVADGN
AKGDVRGYVSNPHVHFDLNEHGKLDVRRAVGTSGTLSVVKDLGLRDLFTGQVEIVSGEIGEDFTYYLVSSEQVPSSVGVG
VLVNPDNTILAAGGFILQLLPGTDDETITKLETNLSQVEPISKLIQKGLTPEEVLAAVLGEEPEVLETVPVRFTCNCSKE
RFARGIIGLGKDEIQQMIDEDGQAEAQCHFCNETYLFTKEELEALRDEI
>Mature_289_residues
MDYLVKAIAYDGKVRAYAANTTETIHEAQRRHNTWPTASAALGRTMTAAVMLGAMLKGEDKLTVKIEGGGPIGAIVADGN
AKGDVRGYVSNPHVHFDLNEHGKLDVRRAVGTSGTLSVVKDLGLRDLFTGQVEIVSGEIGEDFTYYLVSSEQVPSSVGVG
VLVNPDNTILAAGGFILQLLPGTDDETITKLETNLSQVEPISKLIQKGLTPEEVLAAVLGEEPEVLETVPVRFTCNCSKE
RFARGIIGLGKDEIQQMIDEDGQAEAQCHFCNETYLFTKEELEALRDEI

Specific function: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress

COG id: COG1281

COG function: function code O; Disulfide bond chaperones of the HSP33 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HSP33 family

Homologues:

Organism=Escherichia coli, GI87082260, Length=295, Percent_Identity=24.7457627118644, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLO_BACLD (Q65PF0)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_077357.1
- RefSeq:   YP_089757.1
- ProteinModelPortal:   Q65PF0
- SMR:   Q65PF0
- STRING:   Q65PF0
- EnsemblBacteria:   EBBACT00000058350
- EnsemblBacteria:   EBBACT00000062133
- GeneID:   3028451
- GeneID:   3099618
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi00087
- KEGG:   bli:BL00854
- NMPDR:   fig|279010.5.peg.1467
- eggNOG:   COG1281
- GeneTree:   EBGT00050000001636
- HOGENOM:   HBG286231
- OMA:   GYIQNPG
- ProtClustDB:   PRK00114
- BioCyc:   BLIC279010-1:BLI00087-MONOMER
- BioCyc:   BLIC279010:BL00854-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00117
- InterPro:   IPR000397
- InterPro:   IPR016154
- InterPro:   IPR016153
- Gene3D:   G3DSA:3.90.1280.10
- Gene3D:   G3DSA:3.55.30.10
- PIRSF:   PIRSF005261

Pfam domain/function: PF01430 HSP33; SSF64397 Heat_shock_Hsp33_N

EC number: NA

Molecular weight: Translated: 31220; Mature: 31220

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYLVKAIAYDGKVRAYAANTTETIHEAQRRHNTWPTASAALGRTMTAAVMLGAMLKGED
CCHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
KLTVKIEGGGPIGAIVADGNAKGDVRGYVSNPHVHFDLNEHGKLDVRRAVGTSGTLSVVK
EEEEEEECCCCEEEEEECCCCCCCEEEEECCCEEEEECCCCCCEEEHHHCCCCCHHHHHH
DLGLRDLFTGQVEIVSGEIGEDFTYYLVSSEQVPSSVGVGVLVNPDNTILAAGGFILQLL
HCCCHHCCCCEEEEEECCCCCCEEEEEEECCCCCHHHCEEEEECCCCEEEEECCEEEEEE
PGTDDETITKLETNLSQVEPISKLIQKGLTPEEVLAAVLGEEPEVLETVPVRFTCNCSKE
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHEEECEEEEECCCHH
RFARGIIGLGKDEIQQMIDEDGQAEAQCHFCNETYLFTKEELEALRDEI
HHHHHHHCCCHHHHHHHHCCCCCCCEEEEECCCEEEEEHHHHHHHHHCC
>Mature Secondary Structure
MDYLVKAIAYDGKVRAYAANTTETIHEAQRRHNTWPTASAALGRTMTAAVMLGAMLKGED
CCHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
KLTVKIEGGGPIGAIVADGNAKGDVRGYVSNPHVHFDLNEHGKLDVRRAVGTSGTLSVVK
EEEEEEECCCCEEEEEECCCCCCCEEEEECCCEEEEECCCCCCEEEHHHCCCCCHHHHHH
DLGLRDLFTGQVEIVSGEIGEDFTYYLVSSEQVPSSVGVGVLVNPDNTILAAGGFILQLL
HCCCHHCCCCEEEEEECCCCCCEEEEEEECCCCCHHHCEEEEECCCCEEEEECCEEEEEE
PGTDDETITKLETNLSQVEPISKLIQKGLTPEEVLAAVLGEEPEVLETVPVRFTCNCSKE
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHEEECEEEEECCCHH
RFARGIIGLGKDEIQQMIDEDGQAEAQCHFCNETYLFTKEELEALRDEI
HHHHHHHCCCHHHHHHHHCCCCCCCEEEEECCCEEEEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA