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The map label for this gene is yacB

Identifier: 52783927

GI number: 52783927

Start: 83696

End: 84472

Strand: Direct

Name: yacB

Synonym: BLi00086

Alternate gene names: 52783927

Gene position: 83696-84472 (Clockwise)

Preceding gene: 52783926

Following gene: 52783928

Centisome position: 1.98

GC content: 45.43

Gene sequence:

>777_bases
ATGTTGCTTGTTATAGATGTAGGAAATACAAACACCGTCCTTGGCATCTACCACGAAGGAGAGCTTGAATATCATTGGCG
GATTGAGACAAGCCGCCATAAAACGGAAGACGAATTCGGCATGCTTCTTCGTTCTTTATTTGATTATGTCGGACTGATGT
TTGACCAGATCGAGGGGATTATTATTTCATCAGTTGTACCACCGATCATGTTCTCCCTCGAAAGAATGTGTATCAAATAT
TTTCAGATCGAGCCTCAGATTGTCGGTCCGGGAATGAAAACAGGATTAAACATAAAATACGATAATCCGAAAGAAGTCGG
AGCAGACCGCATTGTAAACGCAGTAGCCGCTATTCATCTCTATGGCAGCCCCTTGATTGTCGTTGATTTTGGAACCGCTA
CGACGTACTGTTACATTAATGAGCGCAAGGAATATATGGGTGGTGCGATCGCGCCGGGCATCACGATTTCAACTGAAGCG
CTTTATTCAAGAGCTGCCAAGCTTCCCAGAATTGAAATTGCACGGCCTGATCATATAGTCGGCAAAAGTACGGTCAGCGC
GATGCAGTCCGGAATTCTTTACGGCTATGTCGGACAGGTTGAAGGCATTGTCAAACGGATGAAATGGCAGTCCAAGAAAA
ATCCGAAAGTCATAGCGACGGGCGGCCTTGCTTCCTTGATTGCAGACGAATCGGACTGCATCGATATTGTTGACCCGTTC
CTTACGTTGAAGGGGCTAGAGCTCATTTATGAACGGAATCGTGTTGAAAGTGTATAG

Upstream 100 bases:

>100_bases
CGGTTTGATTCGTTTACAAACAGAATCGGCATCGTGTATTGTATGATGGTAGAATGTTTTATGTCCAAGTAAGAGAAACT
AGTCAAAAGTGGTGATCAGA

Downstream 100 bases:

>100_bases
GAGGATGAGGTATGGATTATTTAGTGAAAGCCATTGCATATGACGGCAAAGTGAGGGCATATGCAGCGAATACAACAGAA
ACGATTCATGAAGCCCAAAG

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MLLVIDVGNTNTVLGIYHEGELEYHWRIETSRHKTEDEFGMLLRSLFDYVGLMFDQIEGIIISSVVPPIMFSLERMCIKY
FQIEPQIVGPGMKTGLNIKYDNPKEVGADRIVNAVAAIHLYGSPLIVVDFGTATTYCYINERKEYMGGAIAPGITISTEA
LYSRAAKLPRIEIARPDHIVGKSTVSAMQSGILYGYVGQVEGIVKRMKWQSKKNPKVIATGGLASLIADESDCIDIVDPF
LTLKGLELIYERNRVESV

Sequences:

>Translated_258_residues
MLLVIDVGNTNTVLGIYHEGELEYHWRIETSRHKTEDEFGMLLRSLFDYVGLMFDQIEGIIISSVVPPIMFSLERMCIKY
FQIEPQIVGPGMKTGLNIKYDNPKEVGADRIVNAVAAIHLYGSPLIVVDFGTATTYCYINERKEYMGGAIAPGITISTEA
LYSRAAKLPRIEIARPDHIVGKSTVSAMQSGILYGYVGQVEGIVKRMKWQSKKNPKVIATGGLASLIADESDCIDIVDPF
LTLKGLELIYERNRVESV
>Mature_258_residues
MLLVIDVGNTNTVLGIYHEGELEYHWRIETSRHKTEDEFGMLLRSLFDYVGLMFDQIEGIIISSVVPPIMFSLERMCIKY
FQIEPQIVGPGMKTGLNIKYDNPKEVGADRIVNAVAAIHLYGSPLIVVDFGTATTYCYINERKEYMGGAIAPGITISTEA
LYSRAAKLPRIEIARPDHIVGKSTVSAMQSGILYGYVGQVEGIVKRMKWQSKKNPKVIATGGLASLIADESDCIDIVDPF
LTLKGLELIYERNRVESV

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_BACLD (Q65PF1)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_077356.2
- RefSeq:   YP_089756.1
- ProteinModelPortal:   Q65PF1
- SMR:   Q65PF1
- STRING:   Q65PF1
- EnsemblBacteria:   EBBACT00000054415
- EnsemblBacteria:   EBBACT00000059021
- GeneID:   3027839
- GeneID:   3097970
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi00086
- KEGG:   bli:BL00853
- NMPDR:   fig|279010.5.peg.1466
- eggNOG:   COG1521
- GeneTree:   EBGT00050000002208
- HOGENOM:   HBG634537
- ProtClustDB:   PRK13318
- BioCyc:   BLIC279010-1:BLI00086-MONOMER
- BioCyc:   BLIC279010:BL00853-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 28710; Mature: 28710

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: ACT_SITE 109-109 BINDING 100-100 BINDING 132-132 BINDING 184-184

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLVIDVGNTNTVLGIYHEGELEYHWRIETSRHKTEDEFGMLLRSLFDYVGLMFDQIEGI
CEEEEEECCCCEEEEEEECCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
IISSVVPPIMFSLERMCIKYFQIEPQIVGPGMKTGLNIKYDNPKEVGADRIVNAVAAIHL
HHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEEEECCHHHHHHHHHHHHHHHEEE
YGSPLIVVDFGTATTYCYINERKEYMGGAIAPGITISTEALYSRAAKLPRIEIARPDHIV
ECCCEEEEEECCCEEEEEEECCHHHCCCCCCCCCEEEHHHHHHHHHCCCEEEECCCCCCC
GKSTVSAMQSGILYGYVGQVEGIVKRMKWQSKKNPKVIATGGLASLIADESDCIDIVDPF
CHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHCCCCCCHHHHHHH
LTLKGLELIYERNRVESV
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLLVIDVGNTNTVLGIYHEGELEYHWRIETSRHKTEDEFGMLLRSLFDYVGLMFDQIEGI
CEEEEEECCCCEEEEEEECCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
IISSVVPPIMFSLERMCIKYFQIEPQIVGPGMKTGLNIKYDNPKEVGADRIVNAVAAIHL
HHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEEEECCHHHHHHHHHHHHHHHEEE
YGSPLIVVDFGTATTYCYINERKEYMGGAIAPGITISTEALYSRAAKLPRIEIARPDHIV
ECCCEEEEEECCCEEEEEEECCHHHCCCCCCCCCEEEHHHHHHHHHCCCEEEECCCCCCC
GKSTVSAMQSGILYGYVGQVEGIVKRMKWQSKKNPKVIATGGLASLIADESDCIDIVDPF
CHHHHHHHHCCCEEEEHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHCCCCCCHHHHHHH
LTLKGLELIYERNRVESV
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA