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The map label for this gene is iolE

Identifier: 52142983

GI number: 52142983

Start: 2387078

End: 2387974

Strand: Direct

Name: iolE

Synonym: BCZK2255

Alternate gene names: 52142983

Gene position: 2387078-2387974 (Clockwise)

Preceding gene: 52142985

Following gene: 52142984

Centisome position: 45.03

GC content: 37.57

Gene sequence:

>897_bases
ATGTTTAAAGAAAATACAGTTAAGCTTGGAATTGCACCAATTGCTTGGACAAATGATGATATGCCAGAGCTAGGGGCAGG
AAATACGTTTGAACAATGTATTAGTGAGATGGCACTAGCTGGATTTAATGGAAGTGAAGTAGGGAATAAATATCCGAGAA
ATACAGTTGTATTAAAAAAATCTTTGGCATTACGAAACTTGGAGATTGCTAGTGCATGGTTTAGTACGTTTTTAACAACG
AAGCCACTTGAAGAGACGGTAGAAGAATTTATTAAGCATAGGGATTTCTTGCATGACATGGGTGCGAAAGTCATCGTTGT
TTCAGAGCAAGGGCATAGTATTCAAGGGTTAATGGATGTACCACTATTTAAAAATAAGCCTGTTTTTACAGAAGAAGAGT
GGAATAAGCTTGCGGATGGATTACATCACCTCGGTAAATTAGCTCAGGAAAAGGGGCTACATATTGTATACCATCATCAT
ATGGGTACGGGTGTTCAAACAACGGCAGAAATTGAAAAGTTAATGGACATGACTAATCCAGCGCTTGTATCTCTGCTTTT
TGATACAGGTCATCTTGTTTTTTCAGGAGAAGAGCCACTTTATATTTTGAAAAAATATTTACCTCGTATTAAACACGTAC
ATTTAAAAGATATTCGTCAAGAAGTAGTAGATACTGTAAAGGAAAACGAATTAAGTTTCCTACAGGCAGTGAAGAATGGG
GCATTTACAGTTCCCGGGGATGGCGTAATTGGATTTGATGAAGTGTTTACTATCCTTGCAAACTCTGATTATCAAGGGTG
GTTTGTGGTAGAAGCAGAGCAAGACCCAGCTTTAGCGAATCCTTTTGAATACGCATTAAAAGCCCGAAAATTTATACAAG
AAAAAGCAGGTCTTTAG

Upstream 100 bases:

>100_bases
TTATATACATGCATATTAATTAGGAAGCTCTCTTTTCAATAACCAGTTAAGAGAATTTGGCGAAATTCTATCACATTTTG
CAAAGAGGAGAGACAAGGGG

Downstream 100 bases:

>100_bases
TTTCCGCATTTTGAGACTATCTCAAGTTAATGATTGGGCAATCAAAAGGTCTTCTTACAAAAGGAGTAAAAAGACAGAGA
CGGTTGATTCTATATTAAAT

Product: myo-inositol catabolism protein

Products: NA

Alternate protein names: 2-keto-myo-inositol dehydratase 1; 2KMI dehydratase 1

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MFKENTVKLGIAPIAWTNDDMPELGAGNTFEQCISEMALAGFNGSEVGNKYPRNTVVLKKSLALRNLEIASAWFSTFLTT
KPLEETVEEFIKHRDFLHDMGAKVIVVSEQGHSIQGLMDVPLFKNKPVFTEEEWNKLADGLHHLGKLAQEKGLHIVYHHH
MGTGVQTTAEIEKLMDMTNPALVSLLFDTGHLVFSGEEPLYILKKYLPRIKHVHLKDIRQEVVDTVKENELSFLQAVKNG
AFTVPGDGVIGFDEVFTILANSDYQGWFVVEAEQDPALANPFEYALKARKFIQEKAGL

Sequences:

>Translated_298_residues
MFKENTVKLGIAPIAWTNDDMPELGAGNTFEQCISEMALAGFNGSEVGNKYPRNTVVLKKSLALRNLEIASAWFSTFLTT
KPLEETVEEFIKHRDFLHDMGAKVIVVSEQGHSIQGLMDVPLFKNKPVFTEEEWNKLADGLHHLGKLAQEKGLHIVYHHH
MGTGVQTTAEIEKLMDMTNPALVSLLFDTGHLVFSGEEPLYILKKYLPRIKHVHLKDIRQEVVDTVKENELSFLQAVKNG
AFTVPGDGVIGFDEVFTILANSDYQGWFVVEAEQDPALANPFEYALKARKFIQEKAGL
>Mature_298_residues
MFKENTVKLGIAPIAWTNDDMPELGAGNTFEQCISEMALAGFNGSEVGNKYPRNTVVLKKSLALRNLEIASAWFSTFLTT
KPLEETVEEFIKHRDFLHDMGAKVIVVSEQGHSIQGLMDVPLFKNKPVFTEEEWNKLADGLHHLGKLAQEKGLHIVYHHH
MGTGVQTTAEIEKLMDMTNPALVSLLFDTGHLVFSGEEPLYILKKYLPRIKHVHLKDIRQEVVDTVKENELSFLQAVKNG
AFTVPGDGVIGFDEVFTILANSDYQGWFVVEAEQDPALANPFEYALKARKFIQEKAGL

Specific function: Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D- (3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)

COG id: COG1082

COG function: function code G; Sugar phosphate isomerases/epimerases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iolE/mocC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IOLE1_BACCZ (Q63B72)

Other databases:

- EMBL:   CP000001
- RefSeq:   YP_083845.1
- ProteinModelPortal:   Q63B72
- SMR:   Q63B72
- STRING:   Q63B72
- EnsemblBacteria:   EBBACT00000043033
- GeneID:   3025429
- GenomeReviews:   CP000001_GR
- KEGG:   bcz:BCZK2255
- eggNOG:   COG1082
- GeneTree:   EBGT00050000002447
- HOGENOM:   HBG654552
- OMA:   DLGKENT
- ProtClustDB:   CLSK810783
- BioCyc:   BCER288681:BCE33L2255-MONOMER
- HAMAP:   MF_01672
- InterPro:   IPR013022
- InterPro:   IPR012307
- Gene3D:   G3DSA:3.20.20.150

Pfam domain/function: PF01261 AP_endonuc_2; SSF51658 Xyl_isomerase-like_TIM-brl

EC number: =4.2.1.44

Molecular weight: Translated: 33410; Mature: 33410

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKENTVKLGIAPIAWTNDDMPELGAGNTFEQCISEMALAGFNGSEVGNKYPRNTVVLKK
CCCCCEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCHHCCCCCCCCEEEEEH
SLALRNLEIASAWFSTFLTTKPLEETVEEFIKHRDFLHDMGAKVIVVSEQGHSIQGLMDV
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEC
PLFKNKPVFTEEEWNKLADGLHHLGKLAQEKGLHIVYHHHMGTGVQTTAEIEKLMDMTNP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHCCCH
ALVSLLFDTGHLVFSGEEPLYILKKYLPRIKHVHLKDIRQEVVDTVKENELSFLQAVKNG
HHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AFTVPGDGVIGFDEVFTILANSDYQGWFVVEAEQDPALANPFEYALKARKFIQEKAGL
CEECCCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFKENTVKLGIAPIAWTNDDMPELGAGNTFEQCISEMALAGFNGSEVGNKYPRNTVVLKK
CCCCCEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCHHCCCCCCCCEEEEEH
SLALRNLEIASAWFSTFLTTKPLEETVEEFIKHRDFLHDMGAKVIVVSEQGHSIQGLMDV
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEC
PLFKNKPVFTEEEWNKLADGLHHLGKLAQEKGLHIVYHHHMGTGVQTTAEIEKLMDMTNP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHCCCH
ALVSLLFDTGHLVFSGEEPLYILKKYLPRIKHVHLKDIRQEVVDTVKENELSFLQAVKNG
HHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AFTVPGDGVIGFDEVFTILANSDYQGWFVVEAEQDPALANPFEYALKARKFIQEKAGL
CEECCCCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA