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The map label for this gene is gntR [H]

Identifier: 52142769

GI number: 52142769

Start: 2608169

End: 2609602

Strand: Direct

Name: gntR [H]

Synonym: BCZK2472

Alternate gene names: 52142769

Gene position: 2608169-2609602 (Clockwise)

Preceding gene: 52142771

Following gene: 52142767

Centisome position: 49.2

GC content: 34.24

Gene sequence:

>1434_bases
ATGAAGATTGTACTGCGTAAAGAATCCAACATACCGTACTACAAGCAAATATATATGCAAATCGTTGAAAGAGTACAAAG
TGGCATGCTTTCGCATGGTGACTCACTTCCATCTTTACGCTCTATGGCCGAAGATTTACAGATTAGCCTATTAACTGTTC
GTAAGGCGTATAAACAGCTAGAAAAGAAAGAATATATACGCATTGAACAAGGTAAAGGTGCTTATATACATAAACATGTA
AAGAAAGATTCCAAACCAATTCCGTATAAATGGCAACAAACGAAAACGATTAATGTTATGCGATCTCAATATGCAATGAA
TCAGCACCGGAAATATTACGATTTTTCACAAGCGATTTTATATCCACGTCTATTGCCAAATCCATTCTTGGCAGACGAAA
TGCATAAAATACTTAATAAAGACCAGATGATCCTAGCAACCTATGGGCCAGTTCAAGGTGATTATGAACTACGGGTTGAA
ATAACAAAATACTTACATGAACACCAGAAATTAGTGACAGACCCATCTCAATTATTAATTACAAGCGGAGCACAACAAGG
AATTGATTTAATTGCTCAAACACTATTAAAACCTGGTGATATTGTATTAGTGGAAAGTCCGTGTTACAGTGCTGCGCTTG
ATATTTTCATCAATAAAGGGGCTCAAATTATACCTGTTCCTCTTGATAATCATGGGGCTCGCTCCGATTTAATCGATGAT
ATTTGTCAAGGTAAAAACCCCGTTTTATTGTATACGAATCCAACTTTCCAGAACCCAACAGGTACAGTAATGAGTAAAGA
ACGGAGAATGGAACTTATAGAACTAGCAGAGTTATATAAGTTTTTTATAATTGAAGATGATTCTTTCGGAGAAATATATT
TTGAAGATGCTATTGTTCCCCCTCCTATCAAAAATTTTGATACAAACGGACACGTACTATATATAAAAGGATTTAGTAAA
ACGTTAGCACCAGGACTGCGTATCGCATCTCTTATTGCCGATGGTCCTATTTTCGCATGGTTATATGCCGTAAAAGGTTC
GATGGATATCGGTAGCCCTTTATTAACACAAAAAGCACTTCTACCGTTTTTACGTGCAGAACGTATGAAAAATCACTTAG
AAAAATTACGTACAGCTTTACAAATTAGACGTGATATAACGATTGATATGTTATCACCACTTAAAGAAATACAATTTGAA
ATACCTGATGGTGGCTTTAATTTATGGATTACTCTTCCTAATTCGATAGATCCTTTTACTTTATTACAAAAAGCAAATGA
AGTAGATGTTTCTTTTTTACCGGGAACAGCTTGTCTATTAAATAACGAAAGAAATAATAACCAATTAAGAATTAGCTATT
CTATGTTAAATGAAAAAGATATGTCGATTGGATTAGAGAAATTACATGATTCAATACGAAACTATAAACTTTAG

Upstream 100 bases:

>100_bases
GTATAACAGTGTATCTATGTATATAACAGTTGCCTAAAATTGTAGTTGATTCTCTTTATATTTTTCGCTTAAATTAAATA
AAAACGAAAAAGGTGAAACC

Downstream 100 bases:

>100_bases
AAACAAATGCACAATCCCTGTAAACTAAAAAGTAAATACCCCAAAATATTTTTGTTTTGGGGTATTATGAAATTTTGAAG
TATGCTAAGTCATTACTATT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MKIVLRKESNIPYYKQIYMQIVERVQSGMLSHGDSLPSLRSMAEDLQISLLTVRKAYKQLEKKEYIRIEQGKGAYIHKHV
KKDSKPIPYKWQQTKTINVMRSQYAMNQHRKYYDFSQAILYPRLLPNPFLADEMHKILNKDQMILATYGPVQGDYELRVE
ITKYLHEHQKLVTDPSQLLITSGAQQGIDLIAQTLLKPGDIVLVESPCYSAALDIFINKGAQIIPVPLDNHGARSDLIDD
ICQGKNPVLLYTNPTFQNPTGTVMSKERRMELIELAELYKFFIIEDDSFGEIYFEDAIVPPPIKNFDTNGHVLYIKGFSK
TLAPGLRIASLIADGPIFAWLYAVKGSMDIGSPLLTQKALLPFLRAERMKNHLEKLRTALQIRRDITIDMLSPLKEIQFE
IPDGGFNLWITLPNSIDPFTLLQKANEVDVSFLPGTACLLNNERNNNQLRISYSMLNEKDMSIGLEKLHDSIRNYKL

Sequences:

>Translated_477_residues
MKIVLRKESNIPYYKQIYMQIVERVQSGMLSHGDSLPSLRSMAEDLQISLLTVRKAYKQLEKKEYIRIEQGKGAYIHKHV
KKDSKPIPYKWQQTKTINVMRSQYAMNQHRKYYDFSQAILYPRLLPNPFLADEMHKILNKDQMILATYGPVQGDYELRVE
ITKYLHEHQKLVTDPSQLLITSGAQQGIDLIAQTLLKPGDIVLVESPCYSAALDIFINKGAQIIPVPLDNHGARSDLIDD
ICQGKNPVLLYTNPTFQNPTGTVMSKERRMELIELAELYKFFIIEDDSFGEIYFEDAIVPPPIKNFDTNGHVLYIKGFSK
TLAPGLRIASLIADGPIFAWLYAVKGSMDIGSPLLTQKALLPFLRAERMKNHLEKLRTALQIRRDITIDMLSPLKEIQFE
IPDGGFNLWITLPNSIDPFTLLQKANEVDVSFLPGTACLLNNERNNNQLRISYSMLNEKDMSIGLEKLHDSIRNYKL
>Mature_477_residues
MKIVLRKESNIPYYKQIYMQIVERVQSGMLSHGDSLPSLRSMAEDLQISLLTVRKAYKQLEKKEYIRIEQGKGAYIHKHV
KKDSKPIPYKWQQTKTINVMRSQYAMNQHRKYYDFSQAILYPRLLPNPFLADEMHKILNKDQMILATYGPVQGDYELRVE
ITKYLHEHQKLVTDPSQLLITSGAQQGIDLIAQTLLKPGDIVLVESPCYSAALDIFINKGAQIIPVPLDNHGARSDLIDD
ICQGKNPVLLYTNPTFQNPTGTVMSKERRMELIELAELYKFFIIEDDSFGEIYFEDAIVPPPIKNFDTNGHVLYIKGFSK
TLAPGLRIASLIADGPIFAWLYAVKGSMDIGSPLLTQKALLPFLRAERMKNHLEKLRTALQIRRDITIDMLSPLKEIQFE
IPDGGFNLWITLPNSIDPFTLLQKANEVDVSFLPGTACLLNNERNNNQLRISYSMLNEKDMSIGLEKLHDSIRNYKL

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=355, Percent_Identity=29.0140845070423, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI33469970, Length=355, Percent_Identity=29.0140845070423, Blast_Score=118, Evalue=1e-26,
Organism=Escherichia coli, GI1790797, Length=473, Percent_Identity=25.369978858351, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1787710, Length=441, Percent_Identity=29.0249433106576, Blast_Score=149, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6321236, Length=384, Percent_Identity=25, Blast_Score=87, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6321929, Length=195, Percent_Identity=24.6153846153846, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321000, Length=382, Percent_Identity=24.3455497382199, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21356535, Length=366, Percent_Identity=25.6830601092896, Blast_Score=114, Evalue=2e-25,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 54602; Mature: 54602

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVLRKESNIPYYKQIYMQIVERVQSGMLSHGDSLPSLRSMAEDLQISLLTVRKAYKQL
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EKKEYIRIEQGKGAYIHKHVKKDSKPIPYKWQQTKTINVMRSQYAMNQHRKYYDFSQAIL
HHHHCEEEECCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YPRLLPNPFLADEMHKILNKDQMILATYGPVQGDYELRVEITKYLHEHQKLVTDPSQLLI
HHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEEEEHHHHHHHHHHHHHHCCCHHHEE
TSGAQQGIDLIAQTLLKPGDIVLVESPCYSAALDIFINKGAQIIPVPLDNHGARSDLIDD
ECCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHH
ICQGKNPVLLYTNPTFQNPTGTVMSKERRMELIELAELYKFFIIEDDSFGEIYFEDAIVP
HHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCEEEECCCCC
PPIKNFDTNGHVLYIKGFSKTLAPGLRIASLIADGPIFAWLYAVKGSMDIGSPLLTQKAL
CCCCCCCCCCCEEEEECCCHHHCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHH
LPFLRAERMKNHLEKLRTALQIRRDITIDMLSPLKEIQFEIPDGGFNLWITLPNSIDPFT
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHCEEECCCCCEEEEEECCCCCCHHH
LLQKANEVDVSFLPGTACLLNNERNNNQLRISYSMLNEKDMSIGLEKLHDSIRNYKL
HHHCCCCCCEEECCCEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKIVLRKESNIPYYKQIYMQIVERVQSGMLSHGDSLPSLRSMAEDLQISLLTVRKAYKQL
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EKKEYIRIEQGKGAYIHKHVKKDSKPIPYKWQQTKTINVMRSQYAMNQHRKYYDFSQAIL
HHHHCEEEECCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YPRLLPNPFLADEMHKILNKDQMILATYGPVQGDYELRVEITKYLHEHQKLVTDPSQLLI
HHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEEEEHHHHHHHHHHHHHHCCCHHHEE
TSGAQQGIDLIAQTLLKPGDIVLVESPCYSAALDIFINKGAQIIPVPLDNHGARSDLIDD
ECCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHH
ICQGKNPVLLYTNPTFQNPTGTVMSKERRMELIELAELYKFFIIEDDSFGEIYFEDAIVP
HHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCEEEECCCCC
PPIKNFDTNGHVLYIKGFSKTLAPGLRIASLIADGPIFAWLYAVKGSMDIGSPLLTQKAL
CCCCCCCCCCCEEEEECCCHHHCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHH
LPFLRAERMKNHLEKLRTALQIRRDITIDMLSPLKEIQFEIPDGGFNLWITLPNSIDPFT
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHCEEECCCCCEEEEEECCCCCCHHH
LLQKANEVDVSFLPGTACLLNNERNNNQLRISYSMLNEKDMSIGLEKLHDSIRNYKL
HHHCCCCCCEEECCCEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]