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The map label for this gene is aspB [H]

Identifier: 52142615

GI number: 52142615

Start: 2741052

End: 2742254

Strand: Direct

Name: aspB [H]

Synonym: BCZK2627

Alternate gene names: 52142615

Gene position: 2741052-2742254 (Clockwise)

Preceding gene: 52142616

Following gene: 52142614

Centisome position: 51.71

GC content: 35.91

Gene sequence:

>1203_bases
TTGATGACTTACACGTTAGCAACTAGAATGAAAGCATTTCAATCTTCTATATTTAGTGAATTAGGGACCTATAAAAAAGA
AAAAATTGCAGCAGGTCACAAAATGATTGATTTAAGTATCGGGAATCCTGATATGCCACCTGCTGATTTCGTAAGAGAAG
AAATGGTACATACAGCAAATCAAAAAGAAAGCTATGGATACACATTAAGTGGCATTCAAGAATTTCACGAAGCTGTAACT
GAATATTACAACAACACTCATAATGTTATATTAAATGCCGATAAAGAAGTTTTATTATTAATGGGTTCACAAGATGGACT
CGTTCATTTACCTATGGTTTATGCGAATCCGGGAGATATTATATTAGTTCCTGACCCAGGATATACAGCTTATGAAACAG
GAATTCAAATGGCCGGTGCAACATCTTACTATATGCCTTTAAAAAAAGAAAATGATTTCTTACCTAACTTAGAGCTAATT
CCTGAAGAAATTGCGGATCAAGCGAAGATGATGATTTTAAACTTCCCAGGGAATCCGGTTCCAGCAATGGCTCATGAAGA
TTTTTTTAAAAAAGTAATCGCATTCGCGAAAAAGCATAACATTATTGTTGTCCATGATTTTGCTTATGCTGAATTTTATT
TTGATGGTAATAAACCAATTAGCTTCCTTTCTGTGCCTGGTGCTAAAGAAGTTGGCGTAGAAATTAACTCTTTGTCAAAA
AGTTATAGTTTAGCAGGTAGCCGTATTGGTTATATGATTGGTAATGAAGAAATTGTCGGGGCACTTACACAATTTAAATC
TAATACAGATTACGGAGTATTTTTACCAATTCAAAAAGCGGCATGTGCTGCACTAAGAAATGGTGCTGCTTTTTGTGAGA
AAAACCGTGGTATTTATCAAGAACGTAGAGATACTTTAGTCGATGGGTTCCGAACATTTGGCTGGCATGTTGAAAAACCA
GCTGGCAGTATGTTCGTCTGGGCCGAAATTCCAAAAGGCTGGACTTCTATAGACTTCGCTTATGCATTAATGGATCGTGC
GAATGTCGTTGTCACACCAGGTCATGCATTCGGACCTCACGGAGAAGGGTTTGTACGCATTGCACTCGTTCAAGATAAAG
TAGTGTTACAACAAGTTGTTGAAAACATTAGAAATAGTGGTATTTTTTCTCTTGAAAAATCAGAAGAATTAGTTAAAAAT
TAA

Upstream 100 bases:

>100_bases
TCAATCATTTTAATTTTCGCAAAAAAGTGATAAAATGTAACCATGTGTTTTCAGAATAATTAAAAATGCAGAAAGAAAAC
ACTGTTTTTTAGGAGGGGTT

Downstream 100 bases:

>100_bases
TTACAACTCCCCTGCTTAACTATAGCAGGGGTATTATTCATTGGAGGTACTTAAATGCATATTAAAGACACTCTTCCTCA
TCGTTATCCATTTTTAATGA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MMTYTLATRMKAFQSSIFSELGTYKKEKIAAGHKMIDLSIGNPDMPPADFVREEMVHTANQKESYGYTLSGIQEFHEAVT
EYYNNTHNVILNADKEVLLLMGSQDGLVHLPMVYANPGDIILVPDPGYTAYETGIQMAGATSYYMPLKKENDFLPNLELI
PEEIADQAKMMILNFPGNPVPAMAHEDFFKKVIAFAKKHNIIVVHDFAYAEFYFDGNKPISFLSVPGAKEVGVEINSLSK
SYSLAGSRIGYMIGNEEIVGALTQFKSNTDYGVFLPIQKAACAALRNGAAFCEKNRGIYQERRDTLVDGFRTFGWHVEKP
AGSMFVWAEIPKGWTSIDFAYALMDRANVVVTPGHAFGPHGEGFVRIALVQDKVVLQQVVENIRNSGIFSLEKSEELVKN

Sequences:

>Translated_400_residues
MMTYTLATRMKAFQSSIFSELGTYKKEKIAAGHKMIDLSIGNPDMPPADFVREEMVHTANQKESYGYTLSGIQEFHEAVT
EYYNNTHNVILNADKEVLLLMGSQDGLVHLPMVYANPGDIILVPDPGYTAYETGIQMAGATSYYMPLKKENDFLPNLELI
PEEIADQAKMMILNFPGNPVPAMAHEDFFKKVIAFAKKHNIIVVHDFAYAEFYFDGNKPISFLSVPGAKEVGVEINSLSK
SYSLAGSRIGYMIGNEEIVGALTQFKSNTDYGVFLPIQKAACAALRNGAAFCEKNRGIYQERRDTLVDGFRTFGWHVEKP
AGSMFVWAEIPKGWTSIDFAYALMDRANVVVTPGHAFGPHGEGFVRIALVQDKVVLQQVVENIRNSGIFSLEKSEELVKN
>Mature_400_residues
MMTYTLATRMKAFQSSIFSELGTYKKEKIAAGHKMIDLSIGNPDMPPADFVREEMVHTANQKESYGYTLSGIQEFHEAVT
EYYNNTHNVILNADKEVLLLMGSQDGLVHLPMVYANPGDIILVPDPGYTAYETGIQMAGATSYYMPLKKENDFLPNLELI
PEEIADQAKMMILNFPGNPVPAMAHEDFFKKVIAFAKKHNIIVVHDFAYAEFYFDGNKPISFLSVPGAKEVGVEINSLSK
SYSLAGSRIGYMIGNEEIVGALTQFKSNTDYGVFLPIQKAACAALRNGAAFCEKNRGIYQERRDTLVDGFRTFGWHVEKP
AGSMFVWAEIPKGWTSIDFAYALMDRANVVVTPGHAFGPHGEGFVRIALVQDKVVLQQVVENIRNSGIFSLEKSEELVKN

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=346, Percent_Identity=24.2774566473988, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI56713254, Length=346, Percent_Identity=24.2774566473988, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI95147551, Length=398, Percent_Identity=23.8693467336683, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI169881279, Length=398, Percent_Identity=23.8693467336683, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI169881281, Length=395, Percent_Identity=22.7848101265823, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI4507369, Length=382, Percent_Identity=23.5602094240838, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1788722, Length=385, Percent_Identity=38.4415584415584, Blast_Score=288, Evalue=6e-79,
Organism=Escherichia coli, GI1786816, Length=382, Percent_Identity=21.2041884816754, Blast_Score=111, Evalue=8e-26,
Organism=Escherichia coli, GI1788627, Length=229, Percent_Identity=25.3275109170306, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71994472, Length=290, Percent_Identity=26.2068965517241, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71994476, Length=290, Percent_Identity=26.2068965517241, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17567369, Length=348, Percent_Identity=26.1494252873563, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17567663, Length=371, Percent_Identity=25.8760107816712, Blast_Score=92, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6322401, Length=389, Percent_Identity=23.3933161953728, Blast_Score=90, Evalue=7e-19,
Organism=Drosophila melanogaster, GI28573069, Length=416, Percent_Identity=21.1538461538462, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24646114, Length=416, Percent_Identity=21.1538461538462, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28573067, Length=416, Percent_Identity=21.1538461538462, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28573065, Length=416, Percent_Identity=21.1538461538462, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI18859735, Length=225, Percent_Identity=26.2222222222222, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 44514; Mature: 44514

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTYTLATRMKAFQSSIFSELGTYKKEKIAAGHKMIDLSIGNPDMPPADFVREEMVHTAN
CCEEHHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCC
QKESYGYTLSGIQEFHEAVTEYYNNTHNVILNADKEVLLLMGSQDGLVHLPMVYANPGDI
CCCCCCEEHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCEEEEEEEEECCCCE
ILVPDPGYTAYETGIQMAGATSYYMPLKKENDFLPNLELIPEEIADQAKMMILNFPGNPV
EEECCCCCCHHHHCEEECCCCEEEEECCCCCCCCCCHHCCCHHHCCCEEEEEEECCCCCC
PAMAHEDFFKKVIAFAKKHNIIVVHDFAYAEFYFDGNKPISFLSVPGAKEVGVEINSLSK
CCCHHHHHHHHHHHHHHCCCEEEEEECEEEEEEECCCCCEEEEECCCCHHHCEEHHHCCH
SYSLAGSRIGYMIGNEEIVGALTQFKSNTDYGVFLPIQKAACAALRNGAAFCEKNRGIYQ
HHHCCCCEEEEEECCHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHCCHHHHHCCCCHHH
ERRDTLVDGFRTFGWHVEKPAGSMFVWAEIPKGWTSIDFAYALMDRANVVVTPGHAFGPH
HHHHHHHHHHHHCCEEEECCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCCC
GEGFVRIALVQDKVVLQQVVENIRNSGIFSLEKSEELVKN
CCCEEEEEEEHHHHHHHHHHHHHHCCCEEEECCHHHHHCC
>Mature Secondary Structure
MMTYTLATRMKAFQSSIFSELGTYKKEKIAAGHKMIDLSIGNPDMPPADFVREEMVHTAN
CCEEHHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCC
QKESYGYTLSGIQEFHEAVTEYYNNTHNVILNADKEVLLLMGSQDGLVHLPMVYANPGDI
CCCCCCEEHHHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCCCEEEEEEEEECCCCE
ILVPDPGYTAYETGIQMAGATSYYMPLKKENDFLPNLELIPEEIADQAKMMILNFPGNPV
EEECCCCCCHHHHCEEECCCCEEEEECCCCCCCCCCHHCCCHHHCCCEEEEEEECCCCCC
PAMAHEDFFKKVIAFAKKHNIIVVHDFAYAEFYFDGNKPISFLSVPGAKEVGVEINSLSK
CCCHHHHHHHHHHHHHHCCCEEEEEECEEEEEEECCCCCEEEEECCCCHHHCEEHHHCCH
SYSLAGSRIGYMIGNEEIVGALTQFKSNTDYGVFLPIQKAACAALRNGAAFCEKNRGIYQ
HHHCCCCEEEEEECCHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHCCHHHHHCCCCHHH
ERRDTLVDGFRTFGWHVEKPAGSMFVWAEIPKGWTSIDFAYALMDRANVVVTPGHAFGPH
HHHHHHHHHHHHCCEEEECCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCCC
GEGFVRIALVQDKVVLQQVVENIRNSGIFSLEKSEELVKN
CCCEEEEEEEHHHHHHHHHHHHHHCCCEEEECCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA