Click here to switch to the map view.

The map label for this gene is fabZ [H]

Identifier: 52142614

GI number: 52142614

Start: 2742309

End: 2742707

Strand: Direct

Name: fabZ [H]

Synonym: BCZK2628

Alternate gene names: 52142614

Gene position: 2742309-2742707 (Clockwise)

Preceding gene: 52142615

Following gene: 52142613

Centisome position: 51.73

GC content: 34.59

Gene sequence:

>399_bases
ATGCATATTAAAGACACTCTTCCTCATCGTTATCCATTTTTAATGATTGATAAAATAACAAATGTAAAACAAGGTGAATC
CGTTACAGGATATAAACTCATTACAAATAACGAATGGTTTATAAATGATAGTCAAAATCATATGCCTCATATATTAATTG
TAGAGGCACTTGCTCAGCTTAGTGCATTTGTACATACAAGTGACTCTGACGGACTAGGCTTCCTTTCCTCGTTAGATGGG
GTTACGTTCCATGAAAAAGTATATCCCGGTGATAAACTTGATTTACATTATGAGTTAACTCGCAATCGCCGAGGTTTTGT
TCTCGGTAAAGGTACCGCAACTGTTAATAATCAACCGATTGTAACGATAGAAAAGCTATTAATATATCAAGCAGAATAG

Upstream 100 bases:

>100_bases
TGGTATTTTTTCTCTTGAAAAATCAGAAGAATTAGTTAAAAATTAATTACAACTCCCCTGCTTAACTATAGCAGGGGTAT
TATTCATTGGAGGTACTTAA

Downstream 100 bases:

>100_bases
AGACCTTTTTATTCGCCAGGGTATCTATCTCCTACCAATTCGTTTCATCAACATGAACAGAGTAAATAAATTACTTAGTT
AGGAGCAGGCAAATGGAAAG

Product: 3-hydroxymyristoyl-(acyl carrier protein) dehydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 132; Mature: 132

Protein sequence:

>132_residues
MHIKDTLPHRYPFLMIDKITNVKQGESVTGYKLITNNEWFINDSQNHMPHILIVEALAQLSAFVHTSDSDGLGFLSSLDG
VTFHEKVYPGDKLDLHYELTRNRRGFVLGKGTATVNNQPIVTIEKLLIYQAE

Sequences:

>Translated_132_residues
MHIKDTLPHRYPFLMIDKITNVKQGESVTGYKLITNNEWFINDSQNHMPHILIVEALAQLSAFVHTSDSDGLGFLSSLDG
VTFHEKVYPGDKLDLHYELTRNRRGFVLGKGTATVNNQPIVTIEKLLIYQAE
>Mature_132_residues
MHIKDTLPHRYPFLMIDKITNVKQGESVTGYKLITNNEWFINDSQNHMPHILIVEALAQLSAFVHTSDSDGLGFLSSLDG
VTFHEKVYPGDKLDLHYELTRNRRGFVLGKGTATVNNQPIVTIEKLLIYQAE

Specific function: Involved In Saturated Fatty Acids Biosynthesis. [C]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=128, Percent_Identity=29.6875, Blast_Score=69, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 14981; Mature: 14981

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIKDTLPHRYPFLMIDKITNVKQGESVTGYKLITNNEWFINDSQNHMPHILIVEALAQL
CCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEECCEEEEECCCCCCCCHHHHHHHHHH
SAFVHTSDSDGLGFLSSLDGVTFHEKVYPGDKLDLHYELTRNRRGFVLGKGTATVNNQPI
HHEEECCCCCCCCCHHHCCCCEEEEEECCCCCEEEEEEECCCCCCEEEECCCEEECCCCE
VTIEKLLIYQAE
EEEEEEEEEECC
>Mature Secondary Structure
MHIKDTLPHRYPFLMIDKITNVKQGESVTGYKLITNNEWFINDSQNHMPHILIVEALAQL
CCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEEECCEEEEECCCCCCCCHHHHHHHHHH
SAFVHTSDSDGLGFLSSLDGVTFHEKVYPGDKLDLHYELTRNRRGFVLGKGTATVNNQPI
HHEEECCCCCCCCCHHHCCCCEEEEEECCCCCEEEEEEECCCCCCEEEECCCEEECCCCE
VTIEKLLIYQAE
EEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 10568751 [H]