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The map label for this gene is hfq

Identifier: 52141772

GI number: 52141772

Start: 3597656

End: 3597880

Strand: Reverse

Name: hfq

Synonym: BCZK3472

Alternate gene names: 52141772

Gene position: 3597880-3597656 (Counterclockwise)

Preceding gene: 52141773

Following gene: 52141780

Centisome position: 67.87

GC content: 30.67

Gene sequence:

>225_bases
ATGAAGCAATCAATCAATATTCAAGATCAGTTTTTAAATCAACTCCGTAAAGAGAATACGTTTGTTACGCTGTACTTATT
AAATGGTTTCCAGCTTCGTGGATTAATTAAAGGATTTGATAATTTTACAGTCCTACTGGAAACAGAAGGTAAGCAACAGC
TTATTTATAAACATGCAATTTCTACATTCGTACCACAAAAAAATGTTTCAATTGAATTAGAGTAG

Upstream 100 bases:

>100_bases
TACAGACGGTGAAAAAACGTCAGAAATTTTACGATACATAGAAGGAAAGCTACAACTAAAGTCGAATAATAGTAAGTAGA
GAAAAAGAGGAGGATTCGAC

Downstream 100 bases:

>100_bases
TAATGAATTATTGTACATAACAAAAAAAGAGCGAGTTTCTCGCTCTTTTTTTATTTGTTATAAAAAATAAATAGTGAAAT
TTAAGCGATTCTAAATACAG

Product: RNA-binding protein Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 74; Mature: 74

Protein sequence:

>74_residues
MKQSINIQDQFLNQLRKENTFVTLYLLNGFQLRGLIKGFDNFTVLLETEGKQQLIYKHAISTFVPQKNVSIELE

Sequences:

>Translated_74_residues
MKQSINIQDQFLNQLRKENTFVTLYLLNGFQLRGLIKGFDNFTVLLETEGKQQLIYKHAISTFVPQKNVSIELE
>Mature_74_residues
MKQSINIQDQFLNQLRKENTFVTLYLLNGFQLRGLIKGFDNFTVLLETEGKQQLIYKHAISTFVPQKNVSIELE

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family

Homologues:

Organism=Escherichia coli, GI1790614, Length=70, Percent_Identity=48.5714285714286, Blast_Score=72, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HFQ_BACAA (C3P4Y3)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002867952.1
- ProteinModelPortal:   C3P4Y3
- SMR:   C3P4Y3
- EnsemblBacteria:   EBBACT00000128900
- GeneID:   7850170
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_3865
- GeneTree:   EBGT00050000002825
- ProtClustDB:   PRK00395
- HAMAP:   MF_00436
- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163
- TIGRFAMs:   TIGR02383

Pfam domain/function: PF01423 LSM; SSF50182 Sm_like_riboprot

EC number: NA

Molecular weight: Translated: 8646; Mature: 8646

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQSINIQDQFLNQLRKENTFVTLYLLNGFQLRGLIKGFDNFTVLLETEGKQQLIYKHAI
CCCCCCCHHHHHHHHHCCCCEEEEEEECCEEEEHHCCCCCCEEEEEECCCCHHHHHHHHH
STFVPQKNVSIELE
HHHCCCCCEEEEEC
>Mature Secondary Structure
MKQSINIQDQFLNQLRKENTFVTLYLLNGFQLRGLIKGFDNFTVLLETEGKQQLIYKHAI
CCCCCCCHHHHHHHHHCCCCEEEEEEECCEEEEHHCCCCCCEEEEEECCCCHHHHHHHHH
STFVPQKNVSIELE
HHHCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA