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The map label for this gene is nuoN [H]

Identifier: 52140271

GI number: 52140271

Start: 5091798

End: 5093318

Strand: Reverse

Name: nuoN [H]

Synonym: BCZK4990

Alternate gene names: 52140271

Gene position: 5093318-5091798 (Counterclockwise)

Preceding gene: 52140270

Following gene: 52140272

Centisome position: 96.08

GC content: 39.71

Gene sequence:

>1521_bases
ATGGATATGAATACGTTACTTAGCTTATCGTGGCATCTCATGGTGCCAGAATTCATCATTCTCGGAGCTGCCATCCTTCT
TTCCATATGTGATTTGTTTTTTAAGCTGAACCATAGATACGTAGCGCTTGGTGCAATCGCGGCGGTCGTATTAGCAATCG
TGTCACTCATTACGCTATATGGCGAACCAGCGGGAGATATTTTAAATGGATCGTTTGTGTTAGATGGATTTTCAAAAGGA
TTTAAAACGTTGTTGTTAGGCGGGGCGGCCCTCATTTTGTGCACCGCAATGAGCGATGATAAGAAAAATCCAATTGAAGA
TAAGGGAGAGTATTATTACTTACTTTTAATGGCGCTTCTTGGGGCGATGTTTATGGCTTCTAGCGTTGATTTCGTTACAC
TTTTCGTCGGTTTAGAATTGCTTTCACTTTCTTCCTACATTTTAGTAGGAATACGAAAACAGAACCGTGCATCAAATGAG
GCAGCAATGAAATATGTCATTAATGGAGGAATTGGAACGGCAATTACACTCTTTGGAATGAGTTATTTATACGGCATTAC
AGGCTCAACTAATATCGTGGATATGCAAAAAGTATTTGCCGGGGAACTGGCTAGTGGCATTCAGTTATTGCTAGCTCTCG
CATTCCTACTCTTACTCGTTGGGCTCTCATTCAAAATTGCGACAGTGCCGTTTCATATGTGGGCACCTGATGTGTATGAG
GGAGCGGCTACACCTGTTACTGCTTTTCTTGGAACGATTTCTAAAATGGCAGGTTTCTTACTCATTATTCGTTTGTTCCT
CATGGTTTTTGCAAGTGTATCGGTGCAAGGAGACATGCAATCTTTATACGGACGTATGAGCATATATATCGCTGTGCTAG
CTAGTCTTACGATGATTATTGGAAATGTAGTCGCATTAAAGCAATATAACGTAAAACGCCTATTTGCTTATTCGGGAATC
GCGCATGCGGGATATTTACTCGTTCCGCTTGTCGCATTATCACCATTTACGATGGATAGTATGTGGTTTTACATGCTTGC
GTATATGCTTATGAATATAGGCGCGTTTGCAATTATTCACGGCTTAATCTTACAAAGCGATAAAGAAAATATCACCATTT
TCACTGGATTATATAAGAAGTCGCCATTTACAGCAATCATGATGACGATTTTTATTTTATCGCTAGCGGGGATACCAGGA
ACTGCTGGTTTCATCGGGAAAATTAACATCTTTTTAGGGGCTCTTCATGTAGAGCCGGCTCATTACGTACTAGCTTCTAT
TATGATGGGGACGACAGTCATTTCATTCGTATATTATTTCCGTATTTTACAACAAATGTTTTTCCGAACGGGAGAAGTAG
AAGAGAAAATTCGCTTGCCACTCAATATAAAGATTGTGATGAGCTTTTGTGCAATTTCGATTGTAATACTAGGGATTGTG
CCGATGATTGGGTACAATTTCTTTTATGAATATTTTCCATTAATGAAAGATTTCTTCTTCTTAGGGAACGTGGTACAATA
G

Upstream 100 bases:

>100_bases
ATATTGCTACTTATCTTCTGCATTATTGCAATTGGCGTAATGCCAGAAATACTAGGGGATCCGCTTCAAAATACATTGAA
AACATTGGGGGTGAAGTAGG

Downstream 100 bases:

>100_bases
TGAAAATAAAAGGTGTGGAGTCGTTACTCTGCGCTTTTTATTTTGTGTGAACTACAACTGAAAATACATATAGGTATACG
TTTTTAAAGAGAAAAATTTC

Product: NADH dehydrogenase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MDMNTLLSLSWHLMVPEFIILGAAILLSICDLFFKLNHRYVALGAIAAVVLAIVSLITLYGEPAGDILNGSFVLDGFSKG
FKTLLLGGAALILCTAMSDDKKNPIEDKGEYYYLLLMALLGAMFMASSVDFVTLFVGLELLSLSSYILVGIRKQNRASNE
AAMKYVINGGIGTAITLFGMSYLYGITGSTNIVDMQKVFAGELASGIQLLLALAFLLLLVGLSFKIATVPFHMWAPDVYE
GAATPVTAFLGTISKMAGFLLIIRLFLMVFASVSVQGDMQSLYGRMSIYIAVLASLTMIIGNVVALKQYNVKRLFAYSGI
AHAGYLLVPLVALSPFTMDSMWFYMLAYMLMNIGAFAIIHGLILQSDKENITIFTGLYKKSPFTAIMMTIFILSLAGIPG
TAGFIGKINIFLGALHVEPAHYVLASIMMGTTVISFVYYFRILQQMFFRTGEVEEKIRLPLNIKIVMSFCAISIVILGIV
PMIGYNFFYEYFPLMKDFFFLGNVVQ

Sequences:

>Translated_506_residues
MDMNTLLSLSWHLMVPEFIILGAAILLSICDLFFKLNHRYVALGAIAAVVLAIVSLITLYGEPAGDILNGSFVLDGFSKG
FKTLLLGGAALILCTAMSDDKKNPIEDKGEYYYLLLMALLGAMFMASSVDFVTLFVGLELLSLSSYILVGIRKQNRASNE
AAMKYVINGGIGTAITLFGMSYLYGITGSTNIVDMQKVFAGELASGIQLLLALAFLLLLVGLSFKIATVPFHMWAPDVYE
GAATPVTAFLGTISKMAGFLLIIRLFLMVFASVSVQGDMQSLYGRMSIYIAVLASLTMIIGNVVALKQYNVKRLFAYSGI
AHAGYLLVPLVALSPFTMDSMWFYMLAYMLMNIGAFAIIHGLILQSDKENITIFTGLYKKSPFTAIMMTIFILSLAGIPG
TAGFIGKINIFLGALHVEPAHYVLASIMMGTTVISFVYYFRILQQMFFRTGEVEEKIRLPLNIKIVMSFCAISIVILGIV
PMIGYNFFYEYFPLMKDFFFLGNVVQ
>Mature_506_residues
MDMNTLLSLSWHLMVPEFIILGAAILLSICDLFFKLNHRYVALGAIAAVVLAIVSLITLYGEPAGDILNGSFVLDGFSKG
FKTLLLGGAALILCTAMSDDKKNPIEDKGEYYYLLLMALLGAMFMASSVDFVTLFVGLELLSLSSYILVGIRKQNRASNE
AAMKYVINGGIGTAITLFGMSYLYGITGSTNIVDMQKVFAGELASGIQLLLALAFLLLLVGLSFKIATVPFHMWAPDVYE
GAATPVTAFLGTISKMAGFLLIIRLFLMVFASVSVQGDMQSLYGRMSIYIAVLASLTMIIGNVVALKQYNVKRLFAYSGI
AHAGYLLVPLVALSPFTMDSMWFYMLAYMLMNIGAFAIIHGLILQSDKENITIFTGLYKKSPFTAIMMTIFILSLAGIPG
TAGFIGKINIFLGALHVEPAHYVLASIMMGTTVISFVYYFRILQQMFFRTGEVEEKIRLPLNIKIVMSFCAISIVILGIV
PMIGYNFFYEYFPLMKDFFFLGNVVQ

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Escherichia coli, GI145693160, Length=479, Percent_Identity=32.9853862212944, Blast_Score=217, Evalue=1e-57,
Organism=Escherichia coli, GI1788831, Length=309, Percent_Identity=27.831715210356, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1788613, Length=381, Percent_Identity=23.0971128608924, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788614, Length=305, Percent_Identity=27.8688524590164, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788827, Length=417, Percent_Identity=23.2613908872902, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 55538; Mature: 55538

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMNTLLSLSWHLMVPEFIILGAAILLSICDLFFKLNHRYVALGAIAAVVLAIVSLITLY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
GEPAGDILNGSFVLDGFSKGFKTLLLGGAALILCTAMSDDKKNPIEDKGEYYYLLLMALL
CCCCCCCCCCCEEECCHHHHHHHHHHCCHHHHHEEECCCCCCCCCCCCCHHHHHHHHHHH
GAMFMASSVDFVTLFVGLELLSLSSYILVGIRKQNRASNEAAMKYVINGGIGTAITLFGM
HHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHEECCHHHHHHHHHH
SYLYGITGSTNIVDMQKVFAGELASGIQLLLALAFLLLLVGLSFKIATVPFHMWAPDVYE
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHC
GAATPVTAFLGTISKMAGFLLIIRLFLMVFASVSVQGDMQSLYGRMSIYIAVLASLTMII
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
GNVVALKQYNVKRLFAYSGIAHAGYLLVPLVALSPFTMDSMWFYMLAYMLMNIGAFAIIH
HHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLILQSDKENITIFTGLYKKSPFTAIMMTIFILSLAGIPGTAGFIGKINIFLGALHVEPA
HHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHEEHCCCHH
HYVLASIMMGTTVISFVYYFRILQQMFFRTGEVEEKIRLPLNIKIVMSFCAISIVILGIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHH
PMIGYNFFYEYFPLMKDFFFLGNVVQ
HHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDMNTLLSLSWHLMVPEFIILGAAILLSICDLFFKLNHRYVALGAIAAVVLAIVSLITLY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
GEPAGDILNGSFVLDGFSKGFKTLLLGGAALILCTAMSDDKKNPIEDKGEYYYLLLMALL
CCCCCCCCCCCEEECCHHHHHHHHHHCCHHHHHEEECCCCCCCCCCCCCHHHHHHHHHHH
GAMFMASSVDFVTLFVGLELLSLSSYILVGIRKQNRASNEAAMKYVINGGIGTAITLFGM
HHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHEECCHHHHHHHHHH
SYLYGITGSTNIVDMQKVFAGELASGIQLLLALAFLLLLVGLSFKIATVPFHMWAPDVYE
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHC
GAATPVTAFLGTISKMAGFLLIIRLFLMVFASVSVQGDMQSLYGRMSIYIAVLASLTMII
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
GNVVALKQYNVKRLFAYSGIAHAGYLLVPLVALSPFTMDSMWFYMLAYMLMNIGAFAIIH
HHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
GLILQSDKENITIFTGLYKKSPFTAIMMTIFILSLAGIPGTAGFIGKINIFLGALHVEPA
HHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHEEHCCCHH
HYVLASIMMGTTVISFVYYFRILQQMFFRTGEVEEKIRLPLNIKIVMSFCAISIVILGIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHH
PMIGYNFFYEYFPLMKDFFFLGNVVQ
HHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]