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The map label for this gene is mmgC [H]

Identifier: 52140220

GI number: 52140220

Start: 5140305

End: 5141435

Strand: Reverse

Name: mmgC [H]

Synonym: BCZK5042

Alternate gene names: 52140220

Gene position: 5141435-5140305 (Counterclockwise)

Preceding gene: 52140218

Following gene: 52140219

Centisome position: 96.99

GC content: 40.32

Gene sequence:

>1131_bases
ATGAACTTTCGTTTTAATGAAGAGCAACAGATGATGAGGAAAATGGTTCGAGATTTTGCGCAGAAGGAAATAGCTCCCTT
TGTTCCTAGTATGGAACAAGGGGTGTTCCCAAAAGAGATTTTGCAGAAGATGGGTGAGCTTGGATTAATGGGAATTCCAG
CGCCTGCAAAATATGGCGGTTCAGAAATGGATTTTATCTCTTACATTTTAGCGATTGAAGAAATTTCAAAGGTAAGCGCA
ACAGTTGGTGTAATTTTAGCGGTACATACGTCAGTTGGGATGAACCCAATTTTATATTTTGGAACAGAAGAACAGAAAGA
GAAATATGTTTCTAAACTTGCGACTGGTGAATATTTAGGCGCATTTGCATTAACAGAACCTAATGCAGGATCAGATGCAG
GGAGTTTGAAATCAAGAGCTGTAAAGAAAGGCGATTACTACATTATTAATGGTTCGAAAGTATTTATTACAAATGGCGGT
GAAGCAAGTACATACATTGTATTCGCTTCTACAAATCCAGAGGCAGGAAAAAGTGGGATTTCTGCATTTATAGTAGAGAA
AGATACACCAGGCTTAATTATTGGAAAAGATGAGCATAAAATGGGACTTTTCGGTTCTCGCACGGTACAACTTACGTTCG
AGGATATGAAAGTGCCGGCTGAGAATTTACTTGGTGAAGAAGGACAAGGATTTAAGGTTGCGATGGCGAATTTAGATGTT
GGACGAATTGGAATTGGAGCGCAAGCACTAGGAATTGCTGAAGCAGCGCTTGCATGTGCAATTGATTATGCGAAAGAACG
TGAGCAATTCGGAAAACCAATTGCGGCGCAGCAAGGGATTGGCTTCAAACTTGCCGATATGGCAACTAGTGTAGAAGCGG
CGCGATTACTTGTATATAGGGCGGCATCGCTAAGAGCGCAAGGATTACCATGTGGTAAGGAAGCATCTATTGCGAAATTA
TTTGCTTCTAAAACAGCTGTTGAAGTTGCGATTGAAGCTGTGCAAGTATTTGGTGGTTACGGTTATACGAAAGACTATCC
AGTAGAAAGATTTTTCCGTGATGCGAAAATCACGCAAATATATGAAGGAACGAGTGAAATACAGAAACTTGTTATTAGCC
GAGCTTTATAA

Upstream 100 bases:

>100_bases
AGGTCGTGGTTTCTACGTTTATGAATAAATTCCCCTTTGTTACAAAATAGTGGTCTTACCAAATTGTTAAAAGGATATAT
AGCAAATGGAGGCGGGGTAT

Downstream 100 bases:

>100_bases
AAGCACAAGGGGGAGACGGGCATGCATTTTAAACTATCAGAAGAACATGAAATGATAAGAAAAATGGTTCGAGACTTTGC
TAAGAACGAAGTAGCACCGA

Product: short-chain acyl-CoA dehydrogenase; butyryl-CoA dehydrogenase

Products: 2-butenoyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MNFRFNEEQQMMRKMVRDFAQKEIAPFVPSMEQGVFPKEILQKMGELGLMGIPAPAKYGGSEMDFISYILAIEEISKVSA
TVGVILAVHTSVGMNPILYFGTEEQKEKYVSKLATGEYLGAFALTEPNAGSDAGSLKSRAVKKGDYYIINGSKVFITNGG
EASTYIVFASTNPEAGKSGISAFIVEKDTPGLIIGKDEHKMGLFGSRTVQLTFEDMKVPAENLLGEEGQGFKVAMANLDV
GRIGIGAQALGIAEAALACAIDYAKEREQFGKPIAAQQGIGFKLADMATSVEAARLLVYRAASLRAQGLPCGKEASIAKL
FASKTAVEVAIEAVQVFGGYGYTKDYPVERFFRDAKITQIYEGTSEIQKLVISRAL

Sequences:

>Translated_376_residues
MNFRFNEEQQMMRKMVRDFAQKEIAPFVPSMEQGVFPKEILQKMGELGLMGIPAPAKYGGSEMDFISYILAIEEISKVSA
TVGVILAVHTSVGMNPILYFGTEEQKEKYVSKLATGEYLGAFALTEPNAGSDAGSLKSRAVKKGDYYIINGSKVFITNGG
EASTYIVFASTNPEAGKSGISAFIVEKDTPGLIIGKDEHKMGLFGSRTVQLTFEDMKVPAENLLGEEGQGFKVAMANLDV
GRIGIGAQALGIAEAALACAIDYAKEREQFGKPIAAQQGIGFKLADMATSVEAARLLVYRAASLRAQGLPCGKEASIAKL
FASKTAVEVAIEAVQVFGGYGYTKDYPVERFFRDAKITQIYEGTSEIQKLVISRAL
>Mature_376_residues
MNFRFNEEQQMMRKMVRDFAQKEIAPFVPSMEQGVFPKEILQKMGELGLMGIPAPAKYGGSEMDFISYILAIEEISKVSA
TVGVILAVHTSVGMNPILYFGTEEQKEKYVSKLATGEYLGAFALTEPNAGSDAGSLKSRAVKKGDYYIINGSKVFITNGG
EASTYIVFASTNPEAGKSGISAFIVEKDTPGLIIGKDEHKMGLFGSRTVQLTFEDMKVPAENLLGEEGQGFKVAMANLDV
GRIGIGAQALGIAEAALACAIDYAKEREQFGKPIAAQQGIGFKLADMATSVEAARLLVYRAASLRAQGLPCGKEASIAKL
FASKTAVEVAIEAVQVFGGYGYTKDYPVERFFRDAKITQIYEGTSEIQKLVISRAL

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=368, Percent_Identity=49.1847826086957, Blast_Score=379, Evalue=1e-105,
Organism=Homo sapiens, GI4501859, Length=373, Percent_Identity=46.9168900804289, Blast_Score=336, Evalue=2e-92,
Organism=Homo sapiens, GI226958412, Length=377, Percent_Identity=41.9098143236074, Blast_Score=307, Evalue=8e-84,
Organism=Homo sapiens, GI226958414, Length=341, Percent_Identity=43.9882697947214, Blast_Score=297, Evalue=1e-80,
Organism=Homo sapiens, GI187960098, Length=378, Percent_Identity=42.5925925925926, Blast_Score=285, Evalue=6e-77,
Organism=Homo sapiens, GI4557231, Length=378, Percent_Identity=42.5925925925926, Blast_Score=285, Evalue=6e-77,
Organism=Homo sapiens, GI7656849, Length=374, Percent_Identity=40.1069518716578, Blast_Score=280, Evalue=2e-75,
Organism=Homo sapiens, GI21361497, Length=350, Percent_Identity=43.1428571428571, Blast_Score=271, Evalue=6e-73,
Organism=Homo sapiens, GI76496475, Length=380, Percent_Identity=38.6842105263158, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI4557235, Length=380, Percent_Identity=38.6842105263158, Blast_Score=240, Evalue=1e-63,
Organism=Homo sapiens, GI4501857, Length=375, Percent_Identity=37.3333333333333, Blast_Score=237, Evalue=1e-62,
Organism=Homo sapiens, GI4503943, Length=377, Percent_Identity=32.6259946949602, Blast_Score=191, Evalue=8e-49,
Organism=Homo sapiens, GI7669494, Length=363, Percent_Identity=32.7823691460055, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI48976061, Length=293, Percent_Identity=32.7645051194539, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI211971008, Length=297, Percent_Identity=32.6599326599327, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI38505218, Length=369, Percent_Identity=28.1842818428184, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI218563752, Length=238, Percent_Identity=27.7310924369748, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI87081958, Length=383, Percent_Identity=32.8981723237598, Blast_Score=197, Evalue=7e-52,
Organism=Escherichia coli, GI1786223, Length=378, Percent_Identity=29.6296296296296, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI87081702, Length=340, Percent_Identity=27.6470588235294, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87082384, Length=302, Percent_Identity=27.1523178807947, Blast_Score=86, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17538396, Length=377, Percent_Identity=38.9920424403183, Blast_Score=303, Evalue=8e-83,
Organism=Caenorhabditis elegans, GI17508101, Length=372, Percent_Identity=42.4731182795699, Blast_Score=301, Evalue=4e-82,
Organism=Caenorhabditis elegans, GI17569725, Length=382, Percent_Identity=44.2408376963351, Blast_Score=301, Evalue=5e-82,
Organism=Caenorhabditis elegans, GI17506239, Length=373, Percent_Identity=39.9463806970509, Blast_Score=299, Evalue=1e-81,
Organism=Caenorhabditis elegans, GI17534899, Length=383, Percent_Identity=44.3864229765013, Blast_Score=298, Evalue=3e-81,
Organism=Caenorhabditis elegans, GI17570075, Length=382, Percent_Identity=41.0994764397906, Blast_Score=290, Evalue=1e-78,
Organism=Caenorhabditis elegans, GI71990804, Length=310, Percent_Identity=46.4516129032258, Blast_Score=259, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI17533517, Length=365, Percent_Identity=39.4520547945205, Blast_Score=258, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI71985184, Length=381, Percent_Identity=37.007874015748, Blast_Score=236, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI17534353, Length=376, Percent_Identity=31.9148936170213, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI71982178, Length=269, Percent_Identity=37.1747211895911, Blast_Score=195, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI71985192, Length=328, Percent_Identity=36.890243902439, Blast_Score=194, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI32563615, Length=225, Percent_Identity=40.4444444444444, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17551932, Length=375, Percent_Identity=31.2, Blast_Score=184, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI17505929, Length=375, Percent_Identity=31.2, Blast_Score=183, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17531909, Length=239, Percent_Identity=33.8912133891213, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17562446, Length=294, Percent_Identity=31.6326530612245, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17531913, Length=191, Percent_Identity=31.9371727748691, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI86563383, Length=315, Percent_Identity=28.2539682539683, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI86563381, Length=315, Percent_Identity=28.2539682539683, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21356377, Length=370, Percent_Identity=49.7297297297297, Blast_Score=379, Evalue=1e-105,
Organism=Drosophila melanogaster, GI24646207, Length=373, Percent_Identity=45.5764075067024, Blast_Score=343, Evalue=2e-94,
Organism=Drosophila melanogaster, GI24666513, Length=373, Percent_Identity=43.9678284182306, Blast_Score=324, Evalue=6e-89,
Organism=Drosophila melanogaster, GI24660351, Length=380, Percent_Identity=43.6842105263158, Blast_Score=306, Evalue=1e-83,
Organism=Drosophila melanogaster, GI21355753, Length=379, Percent_Identity=39.3139841688654, Blast_Score=282, Evalue=2e-76,
Organism=Drosophila melanogaster, GI281363737, Length=347, Percent_Identity=41.2103746397695, Blast_Score=244, Evalue=9e-65,
Organism=Drosophila melanogaster, GI19920834, Length=378, Percent_Identity=32.5396825396825, Blast_Score=184, Evalue=9e-47,
Organism=Drosophila melanogaster, GI221473076, Length=309, Percent_Identity=26.8608414239482, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI45550141, Length=309, Percent_Identity=26.8608414239482, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.2

Molecular weight: Translated: 40563; Mature: 40563

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFRFNEEQQMMRKMVRDFAQKEIAPFVPSMEQGVFPKEILQKMGELGLMGIPAPAKYGG
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHHHHCCCEECCCCCCCCCC
SEMDFISYILAIEEISKVSATVGVILAVHTSVGMNPILYFGTEEQKEKYVSKLATGEYLG
CHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEECCHHHHHHHHHHHHCCHHHC
AFALTEPNAGSDAGSLKSRAVKKGDYYIINGSKVFITNGGEASTYIVFASTNPEAGKSGI
EEEEECCCCCCCCHHHHHHHCCCCCEEEECCCEEEEECCCCCEEEEEEEECCCCCCCCCC
SAFIVEKDTPGLIIGKDEHKMGLFGSRTVQLTFEDMKVPAENLLGEEGQGFKVAMANLDV
EEEEEECCCCCEEEECCCCCCCCCCCEEEEEEEHHHCCCHHHHCCCCCCCEEEEEECCCC
GRIGIGAQALGIAEAALACAIDYAKEREQFGKPIAAQQGIGFKLADMATSVEAARLLVYR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHH
AASLRAQGLPCGKEASIAKLFASKTAVEVAIEAVQVFGGYGYTKDYPVERFFRDAKITQI
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCHHHHH
YEGTSEIQKLVISRAL
HCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNFRFNEEQQMMRKMVRDFAQKEIAPFVPSMEQGVFPKEILQKMGELGLMGIPAPAKYGG
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCHHHHHHHHHCCCEECCCCCCCCCC
SEMDFISYILAIEEISKVSATVGVILAVHTSVGMNPILYFGTEEQKEKYVSKLATGEYLG
CHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEECCHHHHHHHHHHHHCCHHHC
AFALTEPNAGSDAGSLKSRAVKKGDYYIINGSKVFITNGGEASTYIVFASTNPEAGKSGI
EEEEECCCCCCCCHHHHHHHCCCCCEEEECCCEEEEECCCCCEEEEEEEECCCCCCCCCC
SAFIVEKDTPGLIIGKDEHKMGLFGSRTVQLTFEDMKVPAENLLGEEGQGFKVAMANLDV
EEEEEECCCCCEEEECCCCCCCCCCCEEEEEEEHHHCCCHHHHCCCCCCCEEEEEECCCC
GRIGIGAQALGIAEAALACAIDYAKEREQFGKPIAAQQGIGFKLADMATSVEAARLLVYR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHH
AASLRAQGLPCGKEASIAKLFASKTAVEVAIEAVQVFGGYGYTKDYPVERFFRDAKITQI
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCHHHHH
YEGTSEIQKLVISRAL
HCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: butanoyl-CoA; acceptor

Specific reaction: butanoyl-CoA + acceptor = 2-butenoyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]