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The map label for this gene is hup [H]

Identifier: 51894365

GI number: 51894365

Start: 3443065

End: 3443334

Strand: Reverse

Name: hup [H]

Synonym: STH3230

Alternate gene names: 51894365

Gene position: 3443334-3443065 (Counterclockwise)

Preceding gene: 51894366

Following gene: 51894364

Centisome position: 96.56

GC content: 62.59

Gene sequence:

>270_bases
TTGAACAAGCAGGATCTGGTCGCGAGTGTTGCCGAGAAGTCCGGTCTGACCAAGAAGGACGCGGAGAAGGCCCTGAACGC
CGTTGTGGAGTCGATCAAGGAAGCCCTGAAGAAGGGCGACAAGGTCTCGCTCGTCGGCTTCGGCACGTTCGAGGTCCGGA
ACCGGGCTGCCCGTTCGGGGCGCAATCCGCAGACCGGCGAGCCGATCAAGATCCCTGCGGGCAAGGTGCCTGCCTTCCGT
CCGGGCAAGGAGCTGAAGGAGAGCGTATAA

Upstream 100 bases:

>100_bases
GCCGTAAAGGACATGGAAGGAGTTCTGGAAACCTGCGCCGAATACGGCTCAGCGGGAATCATACCCACCCAATTCTGACC
TCGAAAGGGGAGACCGATTC

Downstream 100 bases:

>100_bases
GTCAAGACGGTAAGGGCCGGACCCTGAAGGGGGTCCGGTCTTCGTGCAAGGAGCGGTTGCATGCGCATCGACAAGTTCCT
GAAGGTCTCGCGTATCATCA

Product: non-specific DNA-binding protein

Products: NA

Alternate protein names: DNA-binding protein II; HB [H]

Number of amino acids: Translated: 89; Mature: 89

Protein sequence:

>89_residues
MNKQDLVASVAEKSGLTKKDAEKALNAVVESIKEALKKGDKVSLVGFGTFEVRNRAARSGRNPQTGEPIKIPAGKVPAFR
PGKELKESV

Sequences:

>Translated_89_residues
MNKQDLVASVAEKSGLTKKDAEKALNAVVESIKEALKKGDKVSLVGFGTFEVRNRAARSGRNPQTGEPIKIPAGKVPAFR
PGKELKESV
>Mature_89_residues
MNKQDLVASVAEKSGLTKKDAEKALNAVVESIKEALKKGDKVSLVGFGTFEVRNRAARSGRNPQTGEPIKIPAGKVPAFR
PGKELKESV

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=89, Percent_Identity=55.0561797752809, Blast_Score=105, Evalue=8e-25,
Organism=Escherichia coli, GI1790433, Length=89, Percent_Identity=56.1797752808989, Blast_Score=102, Evalue=7e-24,
Organism=Escherichia coli, GI1788005, Length=89, Percent_Identity=42.6966292134831, Blast_Score=80, Evalue=3e-17,
Organism=Escherichia coli, GI1787141, Length=88, Percent_Identity=36.3636363636364, Blast_Score=73, Evalue=4e-15,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 9518; Mature: 9518

Theoretical pI: Translated: 10.72; Mature: 10.72

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKQDLVASVAEKSGLTKKDAEKALNAVVESIKEALKKGDKVSLVGFGTFEVRNRAARSG
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCC
RNPQTGEPIKIPAGKVPAFRPGKELKESV
CCCCCCCCEECCCCCCCCCCCCHHHHHCC
>Mature Secondary Structure
MNKQDLVASVAEKSGLTKKDAEKALNAVVESIKEALKKGDKVSLVGFGTFEVRNRAARSG
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCC
RNPQTGEPIKIPAGKVPAFRPGKELKESV
CCCCCCCCEECCCCCCCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1644313 [H]