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The map label for this gene is arcB [H]

Identifier: 51599095

GI number: 51599095

Start: 902782

End: 903765

Strand: Direct

Name: arcB [H]

Synonym: BG0869

Alternate gene names: 51599095

Gene position: 902782-903765 (Clockwise)

Preceding gene: 51599094

Following gene: NA

Centisome position: 99.84

GC content: 34.15

Gene sequence:

>984_bases
ATGTATAATTTACGAAATAGGAGCTTTTTAAATCTTTTAGATTTTACAAGCAAAGATATTAGATATTTACTTGATTTATC
GATTGATTTAAAAAAATCAAAATATGCAGGAATTGAAGTGCAGAAACTTAAAGGTAAAAATATGGCTATAATTTTTGAGA
AAGATTCAACAAGAACTCGGTGTGCTTTTGAGATTGCAGCGTATGATCAAGGGGCAAATATTACGTATTTAGGTTCTAGG
GGTAATCAAATAGGCGTAAAAGAGTCTATGATGGATACCGCTAGAGTTCTGGGGCGTATGTATGATGCCATCGGGTTTAG
AGGGTTTTCTCAACAGACTGTTGAATGTTTGGCGAATTATTCCAATGTTCCTGTTTACAATGGACTGACAGATACTGCTC
ATCCAACCCAAATACTAGCCGATTTAATGCCAATAGAAGAGCATAAAGGAAGTTTAAAAGGGGTTAAAATAGTATTTTGT
GGCGACGGTAGGGGGAATGTTGCCAATTCTTTATTGAAAGGCTGTGCTATTATGGGGCTTGATTTTAGAATTTTTGCTCC
TAAAGAGCTTTTTCCAGACTCGAATTTGACGCTTAAGGCTAAGTCTTTAGCCCTAGATAGTGGAGGTAAAATTACAATTA
CAGATTCTAAAGAAGAGGCTGTAAAATGCGCTGATGTTGTGTATACGGATGTGTGGGTATCTATGGGCGAAAATAATTGG
GAAGATAGAATAAATCTTCTAAGGTTTTATCAGGTCAATAAAGAGATTATGGATATGGCAAAAGATAGCGCAATATTTAT
GCATTGTTTACCTGCTTTTCACGATTTAAATACTGTAGTCGGTAAAGATATTTTTGATAAATATGGAATTAATGGAATCG
AAGTTACAGAAGAAATTTTTGAAAGTAAAAATTCAGTTGTTTTTGATATTGCTGAAAATAGAGTACATACCATTAAAGCT
ATTGTGGTAGCGACTTTAGGATAA

Upstream 100 bases:

>100_bases
CTATGCCTTTAGTAAGAGAGGATATTTAATATTTGAGCTAAATAAGCTAAATAAGCTAAATAAAGGCTTTATAAACCAAT
TGTAAATGTTAGGGGTTATT

Downstream 100 bases:

>100_bases
CAGCAATTTATTTTTATATGAAAAAATTATTTAGGAGGAGTGAATGGTATGATTAAAATGCCAAGTAGTTTTACAATAAT
ATTCTCTTTAATTATATTTG

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MYNLRNRSFLNLLDFTSKDIRYLLDLSIDLKKSKYAGIEVQKLKGKNMAIIFEKDSTRTRCAFEIAAYDQGANITYLGSR
GNQIGVKESMMDTARVLGRMYDAIGFRGFSQQTVECLANYSNVPVYNGLTDTAHPTQILADLMPIEEHKGSLKGVKIVFC
GDGRGNVANSLLKGCAIMGLDFRIFAPKELFPDSNLTLKAKSLALDSGGKITITDSKEEAVKCADVVYTDVWVSMGENNW
EDRINLLRFYQVNKEIMDMAKDSAIFMHCLPAFHDLNTVVGKDIFDKYGINGIEVTEEIFESKNSVVFDIAENRVHTIKA
IVVATLG

Sequences:

>Translated_327_residues
MYNLRNRSFLNLLDFTSKDIRYLLDLSIDLKKSKYAGIEVQKLKGKNMAIIFEKDSTRTRCAFEIAAYDQGANITYLGSR
GNQIGVKESMMDTARVLGRMYDAIGFRGFSQQTVECLANYSNVPVYNGLTDTAHPTQILADLMPIEEHKGSLKGVKIVFC
GDGRGNVANSLLKGCAIMGLDFRIFAPKELFPDSNLTLKAKSLALDSGGKITITDSKEEAVKCADVVYTDVWVSMGENNW
EDRINLLRFYQVNKEIMDMAKDSAIFMHCLPAFHDLNTVVGKDIFDKYGINGIEVTEEIFESKNSVVFDIAENRVHTIKA
IVVATLG
>Mature_327_residues
MYNLRNRSFLNLLDFTSKDIRYLLDLSIDLKKSKYAGIEVQKLKGKNMAIIFEKDSTRTRCAFEIAAYDQGANITYLGSR
GNQIGVKESMMDTARVLGRMYDAIGFRGFSQQTVECLANYSNVPVYNGLTDTAHPTQILADLMPIEEHKGSLKGVKIVFC
GDGRGNVANSLLKGCAIMGLDFRIFAPKELFPDSNLTLKAKSLALDSGGKITITDSKEEAVKCADVVYTDVWVSMGENNW
EDRINLLRFYQVNKEIMDMAKDSAIFMHCLPAFHDLNTVVGKDIFDKYGINGIEVTEEIFESKNSVVFDIAENRVHTIKA
IVVATLG

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=326, Percent_Identity=36.8098159509202, Blast_Score=207, Evalue=8e-54,
Organism=Homo sapiens, GI18105007, Length=291, Percent_Identity=25.4295532646048, Blast_Score=82, Evalue=8e-16,
Organism=Escherichia coli, GI1786469, Length=335, Percent_Identity=54.9253731343284, Blast_Score=372, Evalue=1e-104,
Organism=Escherichia coli, GI1790703, Length=332, Percent_Identity=53.0120481927711, Blast_Score=370, Evalue=1e-104,
Organism=Escherichia coli, GI48994908, Length=377, Percent_Identity=26.525198938992, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI2367364, Length=287, Percent_Identity=28.2229965156794, Blast_Score=75, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6322373, Length=285, Percent_Identity=31.9298245614035, Blast_Score=140, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6322331, Length=282, Percent_Identity=26.9503546099291, Blast_Score=93, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24642586, Length=249, Percent_Identity=26.5060240963855, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 36479; Mature: 36479

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNLRNRSFLNLLDFTSKDIRYLLDLSIDLKKSKYAGIEVQKLKGKNMAIIFEKDSTRTR
CCCCCCCCHHHHHHCCCHHHHEEEECCEEECCCCCCCCEEEEECCCCEEEEEECCCCCCE
CAFEIAAYDQGANITYLGSRGNQIGVKESMMDTARVLGRMYDAIGFRGFSQQTVECLANY
EEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCC
SNVPVYNGLTDTAHPTQILADLMPIEEHKGSLKGVKIVFCGDGRGNVANSLLKGCAIMGL
CCCCEECCCCCCCCHHHHHHHHCCHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCC
DFRIFAPKELFPDSNLTLKAKSLALDSGGKITITDSKEEAVKCADVVYTDVWVSMGENNW
CEEEECCHHHCCCCCCEEEEEEEEECCCCEEEEECCHHHHHHHHHHHHEEHHEECCCCCH
EDRINLLRFYQVNKEIMDMAKDSAIFMHCLPAFHDLNTVVGKDIFDKYGINGIEVTEEIF
HHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ESKNSVVFDIAENRVHTIKAIVVATLG
CCCCCEEEEECCCCHHEEEEEEEEECC
>Mature Secondary Structure
MYNLRNRSFLNLLDFTSKDIRYLLDLSIDLKKSKYAGIEVQKLKGKNMAIIFEKDSTRTR
CCCCCCCCHHHHHHCCCHHHHEEEECCEEECCCCCCCCEEEEECCCCEEEEEECCCCCCE
CAFEIAAYDQGANITYLGSRGNQIGVKESMMDTARVLGRMYDAIGFRGFSQQTVECLANY
EEEEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCC
SNVPVYNGLTDTAHPTQILADLMPIEEHKGSLKGVKIVFCGDGRGNVANSLLKGCAIMGL
CCCCEECCCCCCCCHHHHHHHHCCHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCC
DFRIFAPKELFPDSNLTLKAKSLALDSGGKITITDSKEEAVKCADVVYTDVWVSMGENNW
CEEEECCHHHCCCCCCEEEEEEEEECCCCEEEEECCHHHHHHHHHHHHEEHHEECCCCCH
EDRINLLRFYQVNKEIMDMAKDSAIFMHCLPAFHDLNTVVGKDIFDKYGINGIEVTEEIF
HHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
ESKNSVVFDIAENRVHTIKAIVVATLG
CCCCCEEEEECCCCHHEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9402027 [H]