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The map label for this gene is fus-2 [H]

Identifier: 51598946

GI number: 51598946

Start: 733712

End: 735721

Strand: Direct

Name: fus-2 [H]

Synonym: BG0715

Alternate gene names: 51598946

Gene position: 733712-735721 (Clockwise)

Preceding gene: 51598945

Following gene: 51598947

Centisome position: 81.14

GC content: 30.3

Gene sequence:

>2010_bases
ATGAGTATTAGAAATATTGGAATTATGGCTCATATTGATGCTGGCAAAACTACTACTACAGAAAGAATTATTTATTATAC
TGGCAAAAGTCATAAAATAGGAGATGTGGATTCTGGAAATACTATTACTGACTGGATGCCTCAAGAGCAAGAAAGAGGAA
TTACTATTAGTTCAGCTGCTATTACTTGCCATTGGAAAGATTGCCAAATAAATATTATTGATACTCCAGGACATGTTGAT
TTCACAGCAGAAGTTGAAAGATCCCTTCGAGTTCTTGATGGGGGTGTTGTTATTTTTAGCGCTGTTGATGGAATTCAAGC
TCAAACAGAAACTGTTTGGAAACAGTCGGAAAAATATGAAATTCCTAGACTTGCTTATATTAACAAGATGGATAGATTGG
GCGCTAATTTTTTTAAAGTTGTAGGAGATATTGAAAACAAGTTTAAAACTATTCCTTTAATTTTGCAAATTCCAATTGGA
AATGAGAGTAATTTTGAAGGAGTAGTTGATATTATTTTAAACAAAGAGCTTCATTTTGCAATGGAAAATGGAATTCCAAA
ATTAACTTATAGCCCTATTAGAGAAGAATTCGCTGAAAAAGTGGGGTTTTTTAAGAAAAAACTAATAGACATTCTTAGTC
AATTTAGTGAAGAGATTACTCAATTATTTCTTGAAGATAAAGAAATTAGTTTAGATATTATTAAAAGTGAGATCAGAAGA
GGTACTATTTCTAGATTCATTATTCCTGTTTTAATGGGAACTAGTTTAAAAAATATTGGAATAGAACCTTTAATTGATTC
GATTGTAGATTACTTGCCAAGTCCTTTTGAAAAAAACTTTAGTGCTTTTTCTTTAGATGCAAATAAAAAAATTTTAGTTA
ATCCCAATGAAAATAAAAAATTGTCAGCGCTTGTTTTTAAAGTTCAATATTCAAGCGTAATTGCTGCTCATCTTTATTTT
GTTAGAGTTTATTCTGGCGAGATTAATTCTAGTAAAAAAATTTTTAATGCTTCAAATGGCAAGCGTGAAAAGTTTACAAA
AATTTTTAGAGTTTTTTCAAATAAAAATGAACAAATAGATTGCGTAAAAACAGGGGATATTGGTGCTGTTTTAGGATTAA
AGTTTTCTTTTACAGGGGATACTCTTGTTGAAGAAAATAATAATGTTTTACTTGAATCTGTTACGTTTCCAGAACCAGTT
GTTTTAATGTCTGTTGAGCCCGAAAGATCATCAGATGAAGTTAGACTAAGGGAAATTTTTGGAATAATATCTAAAGAAGA
TCCTACTTTTAGTTATTATGAAAGCAAAGAAACAGGGCAATTAATTATATCTGGAATGGGCGAATTACATCTTGAGATTA
TTTTGACAAGAATTAAAGATGAATTCAATCTTAATGTTTATACAGGAAAACCTCAAGTAAGTTATAGAGAGAGTGCAGGT
AAAATTGTAAAAGAAGTTTTTGAGTTTAATAATATCTTTGCTGGCAAAAATATTGATTTTAAAATTGGAATGATCATTAA
ACCTTTGCCACGGGGGGAAGGAAATAAAATCGATTTTGAATGTGACATTAACCCCACAATTAAGTCTGCAATATTTAGGG
GAATTACAACCGCATTTGTAAGTGGAGTTTTTGGGTATCCTATTATTGATATTAATGTTGGTATTTTTTCTATTGTTTCT
GAGACTAGTAAGATTAGCGAGAGCGCTTTTGAATCAATTTCAGGATTTGCTTTTCATAGTATTTTTCAAAAATCGGATCC
TATTAAACTTGAACCAATAATGTTATTAGAAATTAGAACGCCTATTGAGCATACCGGAGAAATTATTTCTAAATTCAATG
TTATGGGGGGTGTTATTCATTCAGTTAGCAATATTGGGGAGTATGATTTAATAAAATCGGAGGCGGCTTTTGAGAAACTT
TTTGGGTATGCTTCTATTTTAAGAAGTTCTACTAAAGGGAGAGGTAGTTTTACTATGGAATTTTCTTATTTTAAGGAAAA
AGTAGGTTAA

Upstream 100 bases:

>100_bases
GCGAGTGCGATATAAAATAACAATTTTATTAAAAAAAGGCTTAACTTATACCAATGATTAGTTTATCTGAATTAAGGCTG
TAGTTATTGTTGGGAATTTT

Downstream 100 bases:

>100_bases
AGTTATTAGTTTTTAAGGTAAAATGGCTTTTCTTGTTTTTGTTATTTTTTAAATCTAATTAATTTTTATTGATGAGTTTT
ATGTAAAAATGATTTTATTC

Product: elongation factor G

Products: NA

Alternate protein names: EF-G 2 [H]

Number of amino acids: Translated: 669; Mature: 668

Protein sequence:

>669_residues
MSIRNIGIMAHIDAGKTTTTERIIYYTGKSHKIGDVDSGNTITDWMPQEQERGITISSAAITCHWKDCQINIIDTPGHVD
FTAEVERSLRVLDGGVVIFSAVDGIQAQTETVWKQSEKYEIPRLAYINKMDRLGANFFKVVGDIENKFKTIPLILQIPIG
NESNFEGVVDIILNKELHFAMENGIPKLTYSPIREEFAEKVGFFKKKLIDILSQFSEEITQLFLEDKEISLDIIKSEIRR
GTISRFIIPVLMGTSLKNIGIEPLIDSIVDYLPSPFEKNFSAFSLDANKKILVNPNENKKLSALVFKVQYSSVIAAHLYF
VRVYSGEINSSKKIFNASNGKREKFTKIFRVFSNKNEQIDCVKTGDIGAVLGLKFSFTGDTLVEENNNVLLESVTFPEPV
VLMSVEPERSSDEVRLREIFGIISKEDPTFSYYESKETGQLIISGMGELHLEIILTRIKDEFNLNVYTGKPQVSYRESAG
KIVKEVFEFNNIFAGKNIDFKIGMIIKPLPRGEGNKIDFECDINPTIKSAIFRGITTAFVSGVFGYPIIDINVGIFSIVS
ETSKISESAFESISGFAFHSIFQKSDPIKLEPIMLLEIRTPIEHTGEIISKFNVMGGVIHSVSNIGEYDLIKSEAAFEKL
FGYASILRSSTKGRGSFTMEFSYFKEKVG

Sequences:

>Translated_669_residues
MSIRNIGIMAHIDAGKTTTTERIIYYTGKSHKIGDVDSGNTITDWMPQEQERGITISSAAITCHWKDCQINIIDTPGHVD
FTAEVERSLRVLDGGVVIFSAVDGIQAQTETVWKQSEKYEIPRLAYINKMDRLGANFFKVVGDIENKFKTIPLILQIPIG
NESNFEGVVDIILNKELHFAMENGIPKLTYSPIREEFAEKVGFFKKKLIDILSQFSEEITQLFLEDKEISLDIIKSEIRR
GTISRFIIPVLMGTSLKNIGIEPLIDSIVDYLPSPFEKNFSAFSLDANKKILVNPNENKKLSALVFKVQYSSVIAAHLYF
VRVYSGEINSSKKIFNASNGKREKFTKIFRVFSNKNEQIDCVKTGDIGAVLGLKFSFTGDTLVEENNNVLLESVTFPEPV
VLMSVEPERSSDEVRLREIFGIISKEDPTFSYYESKETGQLIISGMGELHLEIILTRIKDEFNLNVYTGKPQVSYRESAG
KIVKEVFEFNNIFAGKNIDFKIGMIIKPLPRGEGNKIDFECDINPTIKSAIFRGITTAFVSGVFGYPIIDINVGIFSIVS
ETSKISESAFESISGFAFHSIFQKSDPIKLEPIMLLEIRTPIEHTGEIISKFNVMGGVIHSVSNIGEYDLIKSEAAFEKL
FGYASILRSSTKGRGSFTMEFSYFKEKVG
>Mature_668_residues
SIRNIGIMAHIDAGKTTTTERIIYYTGKSHKIGDVDSGNTITDWMPQEQERGITISSAAITCHWKDCQINIIDTPGHVDF
TAEVERSLRVLDGGVVIFSAVDGIQAQTETVWKQSEKYEIPRLAYINKMDRLGANFFKVVGDIENKFKTIPLILQIPIGN
ESNFEGVVDIILNKELHFAMENGIPKLTYSPIREEFAEKVGFFKKKLIDILSQFSEEITQLFLEDKEISLDIIKSEIRRG
TISRFIIPVLMGTSLKNIGIEPLIDSIVDYLPSPFEKNFSAFSLDANKKILVNPNENKKLSALVFKVQYSSVIAAHLYFV
RVYSGEINSSKKIFNASNGKREKFTKIFRVFSNKNEQIDCVKTGDIGAVLGLKFSFTGDTLVEENNNVLLESVTFPEPVV
LMSVEPERSSDEVRLREIFGIISKEDPTFSYYESKETGQLIISGMGELHLEIILTRIKDEFNLNVYTGKPQVSYRESAGK
IVKEVFEFNNIFAGKNIDFKIGMIIKPLPRGEGNKIDFECDINPTIKSAIFRGITTAFVSGVFGYPIIDINVGIFSIVSE
TSKISESAFESISGFAFHSIFQKSDPIKLEPIMLLEIRTPIEHTGEIISKFNVMGGVIHSVSNIGEYDLIKSEAAFEKLF
GYASILRSSTKGRGSFTMEFSYFKEKVG

Specific function: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=680, Percent_Identity=34.8529411764706, Blast_Score=414, Evalue=1e-115,
Organism=Homo sapiens, GI19923640, Length=705, Percent_Identity=35.0354609929078, Blast_Score=403, Evalue=1e-112,
Organism=Homo sapiens, GI25306283, Length=445, Percent_Identity=40.6741573033708, Blast_Score=310, Evalue=4e-84,
Organism=Homo sapiens, GI25306287, Length=288, Percent_Identity=48.9583333333333, Blast_Score=267, Evalue=2e-71,
Organism=Homo sapiens, GI94966754, Length=138, Percent_Identity=39.8550724637681, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI4503483, Length=148, Percent_Identity=39.1891891891892, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI157426893, Length=180, Percent_Identity=35, Blast_Score=95, Evalue=3e-19,
Organism=Homo sapiens, GI310132016, Length=119, Percent_Identity=37.8151260504202, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI310110807, Length=119, Percent_Identity=37.8151260504202, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI310123363, Length=119, Percent_Identity=37.8151260504202, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI217272894, Length=136, Percent_Identity=35.2941176470588, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI217272892, Length=136, Percent_Identity=35.2941176470588, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI94966752, Length=64, Percent_Identity=45.3125, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1789738, Length=680, Percent_Identity=40.8823529411765, Blast_Score=510, Evalue=1e-146,
Organism=Escherichia coli, GI1790835, Length=482, Percent_Identity=23.0290456431535, Blast_Score=144, Evalue=3e-35,
Organism=Escherichia coli, GI48994988, Length=170, Percent_Identity=35.2941176470588, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788922, Length=150, Percent_Identity=37.3333333333333, Blast_Score=98, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17533571, Length=685, Percent_Identity=34.5985401459854, Blast_Score=398, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI17556745, Length=631, Percent_Identity=29.0015847860539, Blast_Score=263, Evalue=3e-70,
Organism=Caenorhabditis elegans, GI17557151, Length=176, Percent_Identity=37.5, Blast_Score=102, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17506493, Length=160, Percent_Identity=37.5, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71988819, Length=133, Percent_Identity=34.5864661654135, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71988811, Length=133, Percent_Identity=34.5864661654135, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17552882, Length=137, Percent_Identity=32.8467153284672, Blast_Score=73, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6323098, Length=692, Percent_Identity=35.9826589595376, Blast_Score=425, Evalue=1e-119,
Organism=Saccharomyces cerevisiae, GI6322359, Length=775, Percent_Identity=32.7741935483871, Blast_Score=359, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6324707, Length=791, Percent_Identity=25.2844500632111, Blast_Score=151, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6320593, Length=791, Percent_Identity=25.2844500632111, Blast_Score=151, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6323320, Length=152, Percent_Identity=34.2105263157895, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324166, Length=148, Percent_Identity=34.4594594594595, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24582462, Length=687, Percent_Identity=36.8267831149927, Blast_Score=433, Evalue=1e-121,
Organism=Drosophila melanogaster, GI221458488, Length=709, Percent_Identity=31.0296191819464, Blast_Score=343, Evalue=2e-94,
Organism=Drosophila melanogaster, GI24585709, Length=176, Percent_Identity=36.3636363636364, Blast_Score=103, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24585711, Length=176, Percent_Identity=36.3636363636364, Blast_Score=103, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24585713, Length=176, Percent_Identity=36.3636363636364, Blast_Score=103, Evalue=5e-22,
Organism=Drosophila melanogaster, GI78706572, Length=154, Percent_Identity=36.3636363636364, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21357743, Length=606, Percent_Identity=21.1221122112211, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28574573, Length=209, Percent_Identity=28.2296650717703, Blast_Score=86, Evalue=7e-17,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR004540
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 75082; Mature: 74951

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIRNIGIMAHIDAGKTTTTERIIYYTGKSHKIGDVDSGNTITDWMPQEQERGITISSAA
CCCCEEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCEEECCCCCHHHCCEEEEEEE
ITCHWKDCQINIIDTPGHVDFTAEVERSLRVLDGGVVIFSAVDGIQAQTETVWKQSEKYE
EEEEECCCEEEEEECCCCCEEHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHCCCCCC
IPRLAYINKMDRLGANFFKVVGDIENKFKTIPLILQIPIGNESNFEGVVDIILNKELHFA
CCHHHHHHHHHHHCHHHHHHHHHHHHCCEEEEEEEEEECCCCCCCCHHEEEEECCCHHHH
MENGIPKLTYSPIREEFAEKVGFFKKKLIDILSQFSEEITQLFLEDKEISLDIIKSEIRR
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
GTISRFIIPVLMGTSLKNIGIEPLIDSIVDYLPSPFEKNFSAFSLDANKKILVNPNENKK
HHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEECCCCCCE
LSALVFKVQYSSVIAAHLYFVRVYSGEINSSKKIFNASNGKREKFTKIFRVFSNKNEQID
EEEEEEEEHHHHHHHHHEEEEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEE
CVKTGDIGAVLGLKFSFTGDTLVEENNNVLLESVTFPEPVVLMSVEPERSSDEVRLREIF
EEECCCCEEEEEEEEEECCCEEEECCCCEEEEEECCCCCEEEEEECCCCCCCHHHHHHHH
GIISKEDPTFSYYESKETGQLIISGMGELHLEIILTRIKDEFNLNVYTGKPQVSYRESAG
HHHCCCCCCEEEECCCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHH
KIVKEVFEFNNIFAGKNIDFKIGMIIKPLPRGEGNKIDFECDINPTIKSAIFRGITTAFV
HHHHHHHHHHCEECCCCCCEEEEEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHH
SGVFGYPIIDINVGIFSIVSETSKISESAFESISGFAFHSIFQKSDPIKLEPIMLLEIRT
HHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCEEEEEECC
PIEHTGEIISKFNVMGGVIHSVSNIGEYDLIKSEAAFEKLFGYASILRSSTKGRGSFTME
CHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
FSYFKEKVG
HHHHHHHCC
>Mature Secondary Structure 
SIRNIGIMAHIDAGKTTTTERIIYYTGKSHKIGDVDSGNTITDWMPQEQERGITISSAA
CCCEEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCEEECCCCCHHHCCEEEEEEE
ITCHWKDCQINIIDTPGHVDFTAEVERSLRVLDGGVVIFSAVDGIQAQTETVWKQSEKYE
EEEEECCCEEEEEECCCCCEEHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHCCCCCC
IPRLAYINKMDRLGANFFKVVGDIENKFKTIPLILQIPIGNESNFEGVVDIILNKELHFA
CCHHHHHHHHHHHCHHHHHHHHHHHHCCEEEEEEEEEECCCCCCCCHHEEEEECCCHHHH
MENGIPKLTYSPIREEFAEKVGFFKKKLIDILSQFSEEITQLFLEDKEISLDIIKSEIRR
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
GTISRFIIPVLMGTSLKNIGIEPLIDSIVDYLPSPFEKNFSAFSLDANKKILVNPNENKK
HHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHCCCCCCCCCCEEEECCCCEEEECCCCCCE
LSALVFKVQYSSVIAAHLYFVRVYSGEINSSKKIFNASNGKREKFTKIFRVFSNKNEQID
EEEEEEEEHHHHHHHHHEEEEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEE
CVKTGDIGAVLGLKFSFTGDTLVEENNNVLLESVTFPEPVVLMSVEPERSSDEVRLREIF
EEECCCCEEEEEEEEEECCCEEEECCCCEEEEEECCCCCEEEEEECCCCCCCHHHHHHHH
GIISKEDPTFSYYESKETGQLIISGMGELHLEIILTRIKDEFNLNVYTGKPQVSYRESAG
HHHCCCCCCEEEECCCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHH
KIVKEVFEFNNIFAGKNIDFKIGMIIKPLPRGEGNKIDFECDINPTIKSAIFRGITTAFV
HHHHHHHHHHCEECCCCCCEEEEEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHH
SGVFGYPIIDINVGIFSIVSETSKISESAFESISGFAFHSIFQKSDPIKLEPIMLLEIRT
HHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCEEEEEECC
PIEHTGEIISKFNVMGGVIHSVSNIGEYDLIKSEAAFEKLFGYASILRSSTKGRGSFTME
CHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
FSYFKEKVG
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA