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The map label for this gene is thiJ [H]

Identifier: 51598874

GI number: 51598874

Start: 650496

End: 651050

Strand: Direct

Name: thiJ [H]

Synonym: BG0640

Alternate gene names: 51598874

Gene position: 650496-651050 (Clockwise)

Preceding gene: 51598872

Following gene: 51598877

Centisome position: 71.94

GC content: 31.89

Gene sequence:

>555_bases
ATGGTAGTGGGAATTATTCTTGCAAATGGCTTTGAAGATATTGAGGCTATAATCCCGATTGATATTTTAAGACGGGGCAA
TGTTAATATTCAAGTTATCAGCTTAAATGATAACAATGTTGTTACAAGTTCAAAAGGTGTTTCTTTTTTAACAGACGATG
TAATATTAAACTGTAAGGAGAATTATTTTGATTTAATAATTCTTCCGGGAGGCATGCCTGGAGCCACTAATCTTTTTAAT
TCAAAAGAATTAGATTTGATTTTAAAAGATATGAACTCTAGAGGTAAATTTATTGCAGCTATTTGCGCTTCTCCAGCAGT
AGTGCTTGCTGCTAAAGGTCTTTTAGGATCTAATAAGTTTACATGTTATCCGGGTTTGGAGAAAAGTGTGCTTGATGGTG
AGTTTGTAGATAAAAATGTTGTTATTAGCAATAATTTTATTACTTCCAAAGGAGTTGGAACTTCATTTGAATTTGCTTTT
ACTCTTCTTGAAATGGTAAAGGGAAGACAAATAATGGAAAATGTTAAAAAAGCAACCTTGCTTTGTGATAGTTAA

Upstream 100 bases:

>100_bases
AATAAAAGTTTAAGCTGATGTAGCTCAGTTGGTTAGAGCACTCGGCTCATATCCGAGTTGTCGTGGGTTCAAGTCCCTCC
ATCAGCATTAGGGGTTTTAA

Downstream 100 bases:

>100_bases
ACATAAAATTATTTGAAATAATTATGCTAAATAAATCAAATTTAGGTTTTAAAATTATAAATTTTTTGGAATCAAATTAT
AAATGTCTTCAAGAATGGTT

Product: 4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MVVGIILANGFEDIEAIIPIDILRRGNVNIQVISLNDNNVVTSSKGVSFLTDDVILNCKENYFDLIILPGGMPGATNLFN
SKELDLILKDMNSRGKFIAAICASPAVVLAAKGLLGSNKFTCYPGLEKSVLDGEFVDKNVVISNNFITSKGVGTSFEFAF
TLLEMVKGRQIMENVKKATLLCDS

Sequences:

>Translated_184_residues
MVVGIILANGFEDIEAIIPIDILRRGNVNIQVISLNDNNVVTSSKGVSFLTDDVILNCKENYFDLIILPGGMPGATNLFN
SKELDLILKDMNSRGKFIAAICASPAVVLAAKGLLGSNKFTCYPGLEKSVLDGEFVDKNVVISNNFITSKGVGTSFEFAF
TLLEMVKGRQIMENVKKATLLCDS
>Mature_184_residues
MVVGIILANGFEDIEAIIPIDILRRGNVNIQVISLNDNNVVTSSKGVSFLTDDVILNCKENYFDLIILPGGMPGATNLFN
SKELDLILKDMNSRGKFIAAICASPAVVLAAKGLLGSNKFTCYPGLEKSVLDGEFVDKNVVISNNFITSKGVGTSFEFAF
TLLEMVKGRQIMENVKKATLLCDS

Specific function: Involved in biogenesis of ribosomal proteins, probably as a ribosomal protein-folding chaperone. Interacts with ribosomal subunits, ribosomes and polysomes. Confers resistance to oxidative stress [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=183, Percent_Identity=35.5191256830601, Blast_Score=115, Evalue=2e-26,
Organism=Homo sapiens, GI31543380, Length=183, Percent_Identity=35.5191256830601, Blast_Score=115, Evalue=2e-26,
Organism=Escherichia coli, GI87081736, Length=175, Percent_Identity=32.5714285714286, Blast_Score=104, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17531319, Length=167, Percent_Identity=32.3353293413174, Blast_Score=101, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17558714, Length=161, Percent_Identity=36.0248447204969, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28571932, Length=180, Percent_Identity=36.1111111111111, Blast_Score=119, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24653499, Length=180, Percent_Identity=36.1111111111111, Blast_Score=108, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006287
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 19882; Mature: 19882

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVGIILANGFEDIEAIIPIDILRRGNVNIQVISLNDNNVVTSSKGVSFLTDDVILNCKE
CEEEEEEECCCCHHHEECCHHHEECCCCEEEEEEECCCCEEECCCCCEEEECCEEEEECC
NYFDLIILPGGMPGATNLFNSKELDLILKDMNSRGKFIAAICASPAVVLAAKGLLGSNKF
CCEEEEEECCCCCCCCCCCCCCCHHHEEECCCCCCCEEEEECCCCEEEEEECCCCCCCCE
TCYPGLEKSVLDGEFVDKNVVISNNFITSKGVGTSFEFAFTLLEMVKGRQIMENVKKATL
EECCCCCCCCCCCCCCCCEEEEECCEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHEE
LCDS
EECC
>Mature Secondary Structure
MVVGIILANGFEDIEAIIPIDILRRGNVNIQVISLNDNNVVTSSKGVSFLTDDVILNCKE
CEEEEEEECCCCHHHEECCHHHEECCCCEEEEEEECCCCEEECCCCCEEEECCEEEEECC
NYFDLIILPGGMPGATNLFNSKELDLILKDMNSRGKFIAAICASPAVVLAAKGLLGSNKF
CCEEEEEECCCCCCCCCCCCCCCHHHEEECCCCCCCEEEEECCCCEEEEEECCCCCCCCE
TCYPGLEKSVLDGEFVDKNVVISNNFITSKGVGTSFEFAFTLLEMVKGRQIMENVKKATL
EECCCCCCCCCCCCCCCCEEEEECCEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHEE
LCDS
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 9592144 [H]