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The map label for this gene is trxB [H]

Identifier: 51598769

GI number: 51598769

Start: 528627

End: 529607

Strand: Direct

Name: trxB [H]

Synonym: BG0526

Alternate gene names: 51598769

Gene position: 528627-529607 (Clockwise)

Preceding gene: 51598768

Following gene: 51598774

Centisome position: 58.46

GC content: 30.07

Gene sequence:

>981_bases
ATGTTAGAATTTGAAACTATTAATGTAAATCTGACCAAAAAGGAAAATTTATCTCAAAAAGAGATAGAATTTATTGAAGA
TGTAATAATTTTAGGATCTGGTCCGGCTGGATTAACAGCTGGTATTTATTCTGTTATGAGTAATTATAAAGTTACTATTT
TAGAAGGCCCTGAACCTGGAGGACAGCTTACTACAACTACAGAAGTTTATAATTATCCTGGCTTTAAAAATGGAATAAGT
GGTAGAGATTTGATGTTAAATATGAGAGAGCAAGTAGTAAATCTTGGAGCCAAAACTTTTCCCGAAACTGTTTTTTCTAT
AAAAAGGGAGAATAGTATTTTTTACCTTTATACAGAAAATTATATTTATAAAAGTAAAGCTGTTATTATTGCTGTGGGAT
CAAAACCTAAAAAACTTGAAACTCTTAAAAATTCAGATTTATTTTGGAATAAGGGTATTTCGGTTTGTGCTATTTGTGAT
GGACATCTTTTTAAAGGTAAAAGGGTTGCCGTAATTGGTGGAGGCAATACTGCCCTTTCAGAATCAATTTATTTAAGCAA
ATTAGTGGATAAGGTTTATATTATTGTAAGAAAAGATTATCTTAGAGCTATTGCTATGCTAAGAGATAGTGTTGCGAAGT
TGCCTAATATTGAGATTTTTTATAATTCAGAAGCCATAGAAGTAGATGGCGAATCTTCTGTTTCTTCGATTAAGATTTTT
AATGAAAAAGATAATGTTGTAAATAAATTAAAAGTAAATGGTGTATTTATGGCTGTTGGTTATAAGCCGAATACAGAATT
TTTAAAGGGATTTTTAGATTTGGATGAAGAGGGATTTATTATAACTAAAGATATTGTTAAAACAAGTGTTGATGGTGTTT
TTTCGTGTGGAGATGTTAGCAATAAACTTTATGCTCAAGCCATTACTGCTGCTGCTGAAGGGTTTATTGCATCTGTTGAG
TTAGGAAATTTTTTAAAATAG

Upstream 100 bases:

>100_bases
AATATCAATAAACTTGTGAGTCAATCTTAAATATTTAATATTAATTTTAGCAATGCTAAGATTTGTATTGAAGTTTTTAA
GAGAGGCTTAAAATTTATAT

Downstream 100 bases:

>100_bases
TTTTTATTAAGATATTTTTTAGTTTTAGATAAAGCTTTAATTTAATGTTTTAGAGTAGATTTAATTGCCTTTTGATTTCA
AAAATTAAAATGCCTGTTGA

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MLEFETINVNLTKKENLSQKEIEFIEDVIILGSGPAGLTAGIYSVMSNYKVTILEGPEPGGQLTTTTEVYNYPGFKNGIS
GRDLMLNMREQVVNLGAKTFPETVFSIKRENSIFYLYTENYIYKSKAVIIAVGSKPKKLETLKNSDLFWNKGISVCAICD
GHLFKGKRVAVIGGGNTALSESIYLSKLVDKVYIIVRKDYLRAIAMLRDSVAKLPNIEIFYNSEAIEVDGESSVSSIKIF
NEKDNVVNKLKVNGVFMAVGYKPNTEFLKGFLDLDEEGFIITKDIVKTSVDGVFSCGDVSNKLYAQAITAAAEGFIASVE
LGNFLK

Sequences:

>Translated_326_residues
MLEFETINVNLTKKENLSQKEIEFIEDVIILGSGPAGLTAGIYSVMSNYKVTILEGPEPGGQLTTTTEVYNYPGFKNGIS
GRDLMLNMREQVVNLGAKTFPETVFSIKRENSIFYLYTENYIYKSKAVIIAVGSKPKKLETLKNSDLFWNKGISVCAICD
GHLFKGKRVAVIGGGNTALSESIYLSKLVDKVYIIVRKDYLRAIAMLRDSVAKLPNIEIFYNSEAIEVDGESSVSSIKIF
NEKDNVVNKLKVNGVFMAVGYKPNTEFLKGFLDLDEEGFIITKDIVKTSVDGVFSCGDVSNKLYAQAITAAAEGFIASVE
LGNFLK
>Mature_326_residues
MLEFETINVNLTKKENLSQKEIEFIEDVIILGSGPAGLTAGIYSVMSNYKVTILEGPEPGGQLTTTTEVYNYPGFKNGIS
GRDLMLNMREQVVNLGAKTFPETVFSIKRENSIFYLYTENYIYKSKAVIIAVGSKPKKLETLKNSDLFWNKGISVCAICD
GHLFKGKRVAVIGGGNTALSESIYLSKLVDKVYIIVRKDYLRAIAMLRDSVAKLPNIEIFYNSEAIEVDGESSVSSIKIF
NEKDNVVNKLKVNGVFMAVGYKPNTEFLKGFLDLDEEGFIITKDIVKTSVDGVFSCGDVSNKLYAQAITAAAEGFIASVE
LGNFLK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=309, Percent_Identity=37.8640776699029, Blast_Score=202, Evalue=2e-53,
Organism=Escherichia coli, GI87081763, Length=309, Percent_Identity=32.3624595469256, Blast_Score=134, Evalue=9e-33,
Organism=Saccharomyces cerevisiae, GI6321898, Length=311, Percent_Identity=40.5144694533762, Blast_Score=231, Evalue=2e-61,
Organism=Saccharomyces cerevisiae, GI6320560, Length=311, Percent_Identity=40.1929260450161, Blast_Score=224, Evalue=1e-59,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 35940; Mature: 35940

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEFETINVNLTKKENLSQKEIEFIEDVIILGSGPAGLTAGIYSVMSNYKVTILEGPEPG
CCEEEEEEEEEECCCCCCHHHHHHHHEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCC
GQLTTTTEVYNYPGFKNGISGRDLMLNMREQVVNLGAKTFPETVFSIKRENSIFYLYTEN
CCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHEECCCCEEEEEECC
YIYKSKAVIIAVGSKPKKLETLKNSDLFWNKGISVCAICDGHLFKGKRVAVIGGGNTALS
EEEECCEEEEEECCCCHHHHHHCCCCCEECCCCEEEEEECCCEECCCEEEEEECCCCHHH
ESIYLSKLVDKVYIIVRKDYLRAIAMLRDSVAKLPNIEIFYNSEAIEVDGESSVSSIKIF
HHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHCCCEEEEECCCEEEECCCCCCEEEEEE
NEKDNVVNKLKVNGVFMAVGYKPNTEFLKGFLDLDEEGFIITKDIVKTSVDGVFSCGDVS
CCCCCCEEEEEECEEEEEEECCCCHHHHHHHHCCCCCCEEEEHHHHHHHHCCEEECCCCC
NKLYAQAITAAAEGFIASVELGNFLK
HHHHHHHHHHHHCCEEEEECCCCCCC
>Mature Secondary Structure
MLEFETINVNLTKKENLSQKEIEFIEDVIILGSGPAGLTAGIYSVMSNYKVTILEGPEPG
CCEEEEEEEEEECCCCCCHHHHHHHHEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCC
GQLTTTTEVYNYPGFKNGISGRDLMLNMREQVVNLGAKTFPETVFSIKRENSIFYLYTEN
CCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHEECCCCEEEEEECC
YIYKSKAVIIAVGSKPKKLETLKNSDLFWNKGISVCAICDGHLFKGKRVAVIGGGNTALS
EEEECCEEEEEECCCCHHHHHHCCCCCEECCCCEEEEEECCCEECCCEEEEEECCCCHHH
ESIYLSKLVDKVYIIVRKDYLRAIAMLRDSVAKLPNIEIFYNSEAIEVDGESSVSSIKIF
HHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHCCCEEEEECCCEEEECCCCCCEEEEEE
NEKDNVVNKLKVNGVFMAVGYKPNTEFLKGFLDLDEEGFIITKDIVKTSVDGVFSCGDVS
CCCCCCEEEEEECEEEEEEECCCCHHHHHHHHCCCCCCEEEEHHHHHHHHCCEEECCCCC
NKLYAQAITAAAEGFIASVELGNFLK
HHHHHHHHHHHHCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]