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The map label for this gene is engA [H]

Identifier: 51598763

GI number: 51598763

Start: 515546

End: 516847

Strand: Direct

Name: engA [H]

Synonym: BG0520

Alternate gene names: 51598763

Gene position: 515546-516847 (Clockwise)

Preceding gene: 51598761

Following gene: 51598764

Centisome position: 57.01

GC content: 28.26

Gene sequence:

>1302_bases
TTGCTTAGTTACAAAAAGGTTCTTATTGTTGGTAGACCAAATGTTGGGAAATCTGCTTTATTTAATCGAATTTTAGATGC
AAAAAGAAGTATCACTGAGAGTACTTATGGTGTTACTAGAGATTTAGTTGAAGAGGTTTGTAAGGTTGGTTCTTTTAATT
TTAAATTAATTGATACTGGTGGGTTTACGATCTTAAAAGATGAAATTAGCAAAATTGTTGTTCAAAAAGTTTTAAGCTCT
TTAGAGAAAGTTGATTTAATTTTATTAGTTTTAGATGTTAATGAAATTTTACTTGAAGATTATGAGATTATTGAAAGACT
GAGAAAATACAGTAGTAAGGTAATTTTAGTTTTAAATAAAGTAGATACTAAAGATAAGGAATTTTTAGCCCATAAATTTC
ATAATTTAGGGTTTAAGCGGTATTTCCTGGTTAGTGCACTTCATCGTCGAGGCATTACTAAGCTTAGAGATTTTTTAAAA
GTAGAAGTCGGCAGAGTCAATATTGAGGAGGAAGTTAATATTAAGGTTGGGATTATAGGTAAGCCTAATTCAGGCAAATC
TACTCTTATTAATTATTTATCTGGAAATGAAATTTCAATTGTTTCAGACCAGCCCGGCACTACTAGAGATTTTATTAAAA
CCAAGCTAACTAGAAATGGGAAAGTTTTTGAGATTATTGATACAGCTGGAATAAGGCGAAGGGCTAGAGTAAATGAAGTT
GTTGAATATTATTCTGTTAATAGGGCATTGAAAGTAATTGACATAGTGGATATTGTTTTTTTGTTGATTGATGTTGAAGA
AGAATTGACCTCTCAGGATAAAAAGATTGCCCATTATGTTACTAAAAAGGGGAAAGGAATTATTATTGTGTTTAGTAAAT
GGGACCTTTTAGAGGAATCTAAAGGCTATTTTGAAACCTTAAAGGGTCGTGTGAAATTTTTTTTCCCTGTTTTAAATTTT
GCTCCTATATTTAGAATTTCTGTTTATAAAAAGATAGGTCTAGATTCTCTTTTTAAAGAAGCTTTGAAGGTAAAAGATCA
GCTTGAGCTTAAAACCAACACTCCAGATTTAAATAAAATGTTAAATTTATGGATCAAAGACTATCATTTAAACATTTCTC
ATAAAATAAAATATATTACACAAGTTAGCACTAATCCTGTAAAGTTTATTCTTTTTGCAAATAAAATAAAGAATTTTCCA
AATTCTTACTATAATTATTTAGTAAATAATTTACGTAAAATTGGATATAAAAATATTCCAATTTTAGTAGAATTGAGAGA
AAAAATAAGAGATTTAAAGTGA

Upstream 100 bases:

>100_bases
TTTTTTCTTTTCAATATAAACACTCATTTGTAATTGGCATAAATACTAATATTTGCTATTATAATGGAAATATCGGAATA
AATAAAGAGGTATATTTGCT

Downstream 100 bases:

>100_bases
AATATATATTTTTGTTCTTAATAATTAAGAGTCTAAATCTTTTTGCGCTTGAGAGCTTTTTTTATGATTTTGATATAAGG
AGTAAGTATTCAAAATATTT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MLSYKKVLIVGRPNVGKSALFNRILDAKRSITESTYGVTRDLVEEVCKVGSFNFKLIDTGGFTILKDEISKIVVQKVLSS
LEKVDLILLVLDVNEILLEDYEIIERLRKYSSKVILVLNKVDTKDKEFLAHKFHNLGFKRYFLVSALHRRGITKLRDFLK
VEVGRVNIEEEVNIKVGIIGKPNSGKSTLINYLSGNEISIVSDQPGTTRDFIKTKLTRNGKVFEIIDTAGIRRRARVNEV
VEYYSVNRALKVIDIVDIVFLLIDVEEELTSQDKKIAHYVTKKGKGIIIVFSKWDLLEESKGYFETLKGRVKFFFPVLNF
APIFRISVYKKIGLDSLFKEALKVKDQLELKTNTPDLNKMLNLWIKDYHLNISHKIKYITQVSTNPVKFILFANKIKNFP
NSYYNYLVNNLRKIGYKNIPILVELREKIRDLK

Sequences:

>Translated_433_residues
MLSYKKVLIVGRPNVGKSALFNRILDAKRSITESTYGVTRDLVEEVCKVGSFNFKLIDTGGFTILKDEISKIVVQKVLSS
LEKVDLILLVLDVNEILLEDYEIIERLRKYSSKVILVLNKVDTKDKEFLAHKFHNLGFKRYFLVSALHRRGITKLRDFLK
VEVGRVNIEEEVNIKVGIIGKPNSGKSTLINYLSGNEISIVSDQPGTTRDFIKTKLTRNGKVFEIIDTAGIRRRARVNEV
VEYYSVNRALKVIDIVDIVFLLIDVEEELTSQDKKIAHYVTKKGKGIIIVFSKWDLLEESKGYFETLKGRVKFFFPVLNF
APIFRISVYKKIGLDSLFKEALKVKDQLELKTNTPDLNKMLNLWIKDYHLNISHKIKYITQVSTNPVKFILFANKIKNFP
NSYYNYLVNNLRKIGYKNIPILVELREKIRDLK
>Mature_433_residues
MLSYKKVLIVGRPNVGKSALFNRILDAKRSITESTYGVTRDLVEEVCKVGSFNFKLIDTGGFTILKDEISKIVVQKVLSS
LEKVDLILLVLDVNEILLEDYEIIERLRKYSSKVILVLNKVDTKDKEFLAHKFHNLGFKRYFLVSALHRRGITKLRDFLK
VEVGRVNIEEEVNIKVGIIGKPNSGKSTLINYLSGNEISIVSDQPGTTRDFIKTKLTRNGKVFEIIDTAGIRRRARVNEV
VEYYSVNRALKVIDIVDIVFLLIDVEEELTSQDKKIAHYVTKKGKGIIIVFSKWDLLEESKGYFETLKGRVKFFFPVLNF
APIFRISVYKKIGLDSLFKEALKVKDQLELKTNTPDLNKMLNLWIKDYHLNISHKIKYITQVSTNPVKFILFANKIKNFP
NSYYNYLVNNLRKIGYKNIPILVELREKIRDLK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=457, Percent_Identity=29.9781181619256, Blast_Score=221, Evalue=6e-59,
Organism=Escherichia coli, GI2367268, Length=92, Percent_Identity=41.304347826087, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788919, Length=117, Percent_Identity=34.1880341880342, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17507259, Length=94, Percent_Identity=41.4893617021277, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323665, Length=334, Percent_Identity=29.0419161676647, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI45550813, Length=110, Percent_Identity=37.2727272727273, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 50004; Mature: 50004

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSYKKVLIVGRPNVGKSALFNRILDAKRSITESTYGVTRDLVEEVCKVGSFNFKLIDTG
CCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
GFTILKDEISKIVVQKVLSSLEKVDLILLVLDVNEILLEDYEIIERLRKYSSKVILVLNK
CCEEEHHHHHHHHHHHHHHHHHHHEEEEEEECHHHHHHHHHHHHHHHHHCCCEEEEEEEC
VDTKDKEFLAHKFHNLGFKRYFLVSALHRRGITKLRDFLKVEVGRVNIEEEVNIKVGIIG
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHCEEEECEECEEEEEEEE
KPNSGKSTLINYLSGNEISIVSDQPGTTRDFIKTKLTRNGKVFEIIDTAGIRRRARVNEV
CCCCCHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHH
VEYYSVNRALKVIDIVDIVFLLIDVEEELTSQDKKIAHYVTKKGKGIIIVFSKWDLLEES
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHCCCCEEEEEEECCCHHHHC
KGYFETLKGRVKFFFPVLNFAPIFRISVYKKIGLDSLFKEALKVKDQLELKTNTPDLNKM
CCHHHHHHCHHHEEHHHHCCCHHHHHHHHHHHCHHHHHHHHHCCHHHEEEECCCCCHHHH
LNLWIKDYHLNISHKIKYITQVSTNPVKFILFANKIKNFPNSYYNYLVNNLRKIGYKNIP
HHHHHHHEEECHHHHEEEEEEECCCCEEEEEEHHHHCCCCHHHHHHHHHHHHHCCCCCCC
ILVELREKIRDLK
CHHHHHHHHCCCC
>Mature Secondary Structure
MLSYKKVLIVGRPNVGKSALFNRILDAKRSITESTYGVTRDLVEEVCKVGSFNFKLIDTG
CCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECC
GFTILKDEISKIVVQKVLSSLEKVDLILLVLDVNEILLEDYEIIERLRKYSSKVILVLNK
CCEEEHHHHHHHHHHHHHHHHHHHEEEEEEECHHHHHHHHHHHHHHHHHCCCEEEEEEEC
VDTKDKEFLAHKFHNLGFKRYFLVSALHRRGITKLRDFLKVEVGRVNIEEEVNIKVGIIG
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHCEEEECEECEEEEEEEE
KPNSGKSTLINYLSGNEISIVSDQPGTTRDFIKTKLTRNGKVFEIIDTAGIRRRARVNEV
CCCCCHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHH
VEYYSVNRALKVIDIVDIVFLLIDVEEELTSQDKKIAHYVTKKGKGIIIVFSKWDLLEES
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHCCCCEEEEEEECCCHHHHC
KGYFETLKGRVKFFFPVLNFAPIFRISVYKKIGLDSLFKEALKVKDQLELKTNTPDLNKM
CCHHHHHHCHHHEEHHHHCCCHHHHHHHHHHHCHHHHHHHHHCCHHHEEEECCCCCHHHH
LNLWIKDYHLNISHKIKYITQVSTNPVKFILFANKIKNFPNSYYNYLVNNLRKIGYKNIP
HHHHHHHEEECHHHHEEEEEEECCCCEEEEEEHHHHCCCCHHHHHHHHHHHHHCCCCCCC
ILVELREKIRDLK
CHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA