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The map label for this gene is xylB

Identifier: 51598177

GI number: 51598177

Start: 4645197

End: 4646651

Strand: Direct

Name: xylB

Synonym: YPTB3892

Alternate gene names: 51598177

Gene position: 4645197-4646651 (Clockwise)

Preceding gene: 51598176

Following gene: 51598183

Centisome position: 97.9

GC content: 52.99

Gene sequence:

>1455_bases
ATGTATGTTGGTATCGACCTGGGCACCTCCGGCGTTAAAGCTATTTTACTGGCCGAAAACGGGCGAGTAATTGCCAGCCA
AAACGCAGCACTGGTGGTTTCTCGCCCACATCCTTTATGGTCTGAACAAAACCCCGCTGATTGGTGGCAAGCAACCGATC
AGGTCATGCAAGCACTGGCCGCAGAACACGATATGCAGCAAGTGAAAGCGCTCGGGCTGACCGGGCAAATGCACGGGGCA
ACCTTGCTAGATAAACAACATCAGGTGCTGCGCCCCGCCATTTTATGGAATGACGGCCGCAGTTTTTCCCAGTGCCAAAC
ATTGGAGCAAGCGGTACCGGCATCACGCCAGATAACCGGTAACTTGATGATGCCGGGCTTTACCGCCCCCAAATTGCAGT
GGCTGGCAGAACATGAACCAGACATGTTTCAATGTATCGATAAAGTATTATTACCAAAAGATTATCTGCGCTTCCTGATG
AGCGGTGATTTTGCCACTGATATGTCTGATGCTGCCGGTACGATGTGGTTGAATATCGCACAACGTGACTGGAGTGATGA
GATGTTGGCTGCTTGTGGTTTAGGCCGTCAGCACATGCCAACCTTGTTTGAAGGTAACCAAATAACCGGCCATGTCAGTG
CGGATATTGCCAAACGTTGGGGTATCAACAGGATACCGATTGTCGCCGGCGGTGGCGATAATGCAGCCGGGGCGGTGGGG
GTTGGGCTGTATCAGCCCGGACAGGCGATGTTGTCACTGGGGACATCCGGCGTCTATTTTGCAGTCAGCGAGGGTTTTCT
CAGTAATCCAGCCAGTGCGGTTCACAGTTTTTGCCACGCACTGCCTAATACTTGGCATTTGATGTCAGTCATGCTCAGTG
CCGCCTCGTGTTTGGATTGGGCCTGCCAACTCACTGGGGCCGAGAGCGTTCCCGCGTTGATTGCTGAGGTAGAAAAAACC
CCAATGGCTGCAACGCCAGTGTGGTTCCTACCCTATCTTTCCGGCGAACGCACCCCTCATAACAACCCTAAGGCTAAAGG
GGCGTTTTGGGGCTTCACCCATGAACATAGGCGGCCAGATTTAGCCCGCGCAGTATTGGAAGGTGTCGGGTTCGCACTTG
CAGATGGAATGGATGCTCTCCATGCCAGTGGGCTACAACCGAAATCAGTCACATTAATTGGCGGCGGCGCTCGCAGTGCC
TACTGGCGACAAATGCTGGCTGATATCAGTGGCCAAACGCTGGAATATCGCACCGGCGGTGATGTTGGCCCCGCGCTGGG
CGCTGCCCGGTTGGCTCAAATCGCCATGAACCCAGATGTATCACTGGCTGATTTATTGCCTGCACTGGCGTTGGAACAAA
CGCATTTACCGGATCCACAAAAGCATCACTATTACACCGATCGCCGGGTAACCTTTAAAAAACTTTATCAACAATTGCTG
CCATTGTGTGAGTAG

Upstream 100 bases:

>100_bases
CTGGGTTGACCGCTTACTGAGCTTATACACCCTACCGGGTCGTCCTTAGAGGCGGCCAAAATGGCGAGTAGAATAGCCGA
TTAAAATTTGAGGAAAGCAT

Downstream 100 bases:

>100_bases
TTGTCAAGAGTGCGAATAAACACCGTGCTGGGTAATTCATTATTACTCAGCACATTTTTATAGGGCCACGGCTCACACAC
TAATAATAATTAATCTTAAT

Product: xylulose kinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MYVGIDLGTSGVKAILLAENGRVIASQNAALVVSRPHPLWSEQNPADWWQATDQVMQALAAEHDMQQVKALGLTGQMHGA
TLLDKQHQVLRPAILWNDGRSFSQCQTLEQAVPASRQITGNLMMPGFTAPKLQWLAEHEPDMFQCIDKVLLPKDYLRFLM
SGDFATDMSDAAGTMWLNIAQRDWSDEMLAACGLGRQHMPTLFEGNQITGHVSADIAKRWGINRIPIVAGGGDNAAGAVG
VGLYQPGQAMLSLGTSGVYFAVSEGFLSNPASAVHSFCHALPNTWHLMSVMLSAASCLDWACQLTGAESVPALIAEVEKT
PMAATPVWFLPYLSGERTPHNNPKAKGAFWGFTHEHRRPDLARAVLEGVGFALADGMDALHASGLQPKSVTLIGGGARSA
YWRQMLADISGQTLEYRTGGDVGPALGAARLAQIAMNPDVSLADLLPALALEQTHLPDPQKHHYYTDRRVTFKKLYQQLL
PLCE

Sequences:

>Translated_484_residues
MYVGIDLGTSGVKAILLAENGRVIASQNAALVVSRPHPLWSEQNPADWWQATDQVMQALAAEHDMQQVKALGLTGQMHGA
TLLDKQHQVLRPAILWNDGRSFSQCQTLEQAVPASRQITGNLMMPGFTAPKLQWLAEHEPDMFQCIDKVLLPKDYLRFLM
SGDFATDMSDAAGTMWLNIAQRDWSDEMLAACGLGRQHMPTLFEGNQITGHVSADIAKRWGINRIPIVAGGGDNAAGAVG
VGLYQPGQAMLSLGTSGVYFAVSEGFLSNPASAVHSFCHALPNTWHLMSVMLSAASCLDWACQLTGAESVPALIAEVEKT
PMAATPVWFLPYLSGERTPHNNPKAKGAFWGFTHEHRRPDLARAVLEGVGFALADGMDALHASGLQPKSVTLIGGGARSA
YWRQMLADISGQTLEYRTGGDVGPALGAARLAQIAMNPDVSLADLLPALALEQTHLPDPQKHHYYTDRRVTFKKLYQQLL
PLCE
>Mature_484_residues
MYVGIDLGTSGVKAILLAENGRVIASQNAALVVSRPHPLWSEQNPADWWQATDQVMQALAAEHDMQQVKALGLTGQMHGA
TLLDKQHQVLRPAILWNDGRSFSQCQTLEQAVPASRQITGNLMMPGFTAPKLQWLAEHEPDMFQCIDKVLLPKDYLRFLM
SGDFATDMSDAAGTMWLNIAQRDWSDEMLAACGLGRQHMPTLFEGNQITGHVSADIAKRWGINRIPIVAGGGDNAAGAVG
VGLYQPGQAMLSLGTSGVYFAVSEGFLSNPASAVHSFCHALPNTWHLMSVMLSAASCLDWACQLTGAESVPALIAEVEKT
PMAATPVWFLPYLSGERTPHNNPKAKGAFWGFTHEHRRPDLARAVLEGVGFALADGMDALHASGLQPKSVTLIGGGARSA
YWRQMLADISGQTLEYRTGGDVGPALGAARLAQIAMNPDVSLADLLPALALEQTHLPDPQKHHYYTDRRVTFKKLYQQLL
PLCE

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=434, Percent_Identity=23.2718894009217, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI189409120, Length=433, Percent_Identity=23.3256351039261, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI4504007, Length=433, Percent_Identity=23.5565819861432, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI41393575, Length=432, Percent_Identity=23.1481481481481, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI164663828, Length=536, Percent_Identity=25.3731343283582, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI164663830, Length=560, Percent_Identity=24.2857142857143, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI18860918, Length=274, Percent_Identity=26.6423357664234, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI1789987, Length=482, Percent_Identity=71.7842323651452, Blast_Score=697, Evalue=0.0,
Organism=Escherichia coli, GI1790005, Length=492, Percent_Identity=25.4065040650407, Blast_Score=140, Evalue=3e-34,
Organism=Escherichia coli, GI1790361, Length=485, Percent_Identity=24.5360824742268, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787789, Length=372, Percent_Identity=27.4193548387097, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1789168, Length=414, Percent_Identity=24.3961352657005, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17535599, Length=453, Percent_Identity=22.9580573951435, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17554530, Length=449, Percent_Identity=21.380846325167, Blast_Score=89, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6321633, Length=330, Percent_Identity=23.030303030303, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17864214, Length=473, Percent_Identity=23.8900634249471, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24654573, Length=416, Percent_Identity=24.5192307692308, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21356607, Length=507, Percent_Identity=23.2741617357002, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19920476, Length=492, Percent_Identity=23.5772357723577, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 52464; Mature: 52464

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00933 FGGY_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVGIDLGTSGVKAILLAENGRVIASQNAALVVSRPHPLWSEQNPADWWQATDQVMQALA
CEEEEEECCCCCEEEEEECCCEEEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
AEHDMQQVKALGLTGQMHGATLLDKQHQVLRPAILWNDGRSFSQCQTLEQAVPASRQITG
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHCCCCCCCCC
NLMMPGFTAPKLQWLAEHEPDMFQCIDKVLLPKDYLRFLMSGDFATDMSDAAGTMWLNIA
CEECCCCCCHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCEEEEEEH
QRDWSDEMLAACGLGRQHMPTLFEGNQITGHVSADIAKRWGINRIPIVAGGGDNAAGAVG
HCCCHHHHHHHHCCCCCCCCCEECCCEEEEEHHHHHHHHCCCCCCEEEECCCCCCCCEEE
VGLYQPGQAMLSLGTSGVYFAVSEGFLSNPASAVHSFCHALPNTWHLMSVMLSAASCLDW
ECCCCCCHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ACQLTGAESVPALIAEVEKTPMAATPVWFLPYLSGERTPHNNPKAKGAFWGFTHEHRRPD
HHHCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHCCCH
LARAVLEGVGFALADGMDALHASGLQPKSVTLIGGGARSAYWRQMLADISGQTLEYRTGG
HHHHHHHHCCHHHHCCHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEECCCC
DVGPALGAARLAQIAMNPDVSLADLLPALALEQTHLPDPQKHHYYTDRRVTFKKLYQQLL
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHCCEECCCCHHHHHHHHHHC
PLCE
CCCC
>Mature Secondary Structure
MYVGIDLGTSGVKAILLAENGRVIASQNAALVVSRPHPLWSEQNPADWWQATDQVMQALA
CEEEEEECCCCCEEEEEECCCEEEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
AEHDMQQVKALGLTGQMHGATLLDKQHQVLRPAILWNDGRSFSQCQTLEQAVPASRQITG
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHCCCCCCCCC
NLMMPGFTAPKLQWLAEHEPDMFQCIDKVLLPKDYLRFLMSGDFATDMSDAAGTMWLNIA
CEECCCCCCHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCEEEEEEH
QRDWSDEMLAACGLGRQHMPTLFEGNQITGHVSADIAKRWGINRIPIVAGGGDNAAGAVG
HCCCHHHHHHHHCCCCCCCCCEECCCEEEEEHHHHHHHHCCCCCCEEEECCCCCCCCEEE
VGLYQPGQAMLSLGTSGVYFAVSEGFLSNPASAVHSFCHALPNTWHLMSVMLSAASCLDW
ECCCCCCHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ACQLTGAESVPALIAEVEKTPMAATPVWFLPYLSGERTPHNNPKAKGAFWGFTHEHRRPD
HHHCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHCCCH
LARAVLEGVGFALADGMDALHASGLQPKSVTLIGGGARSAYWRQMLADISGQTLEYRTGG
HHHHHHHHCCHHHHCCHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEECCCC
DVGPALGAARLAQIAMNPDVSLADLLPALALEQTHLPDPQKHHYYTDRRVTFKKLYQQLL
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCHHCCEECCCCHHHHHHHHHHC
PLCE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6320721; 8041620; 9278503 [H]