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The map label for this gene is dsbC

Identifier: 51597477

GI number: 51597477

Start: 3724229

End: 3724945

Strand: Reverse

Name: dsbC

Synonym: YPTB3166

Alternate gene names: 51597477

Gene position: 3724945-3724229 (Counterclockwise)

Preceding gene: 51597478

Following gene: 51597476

Centisome position: 78.51

GC content: 45.61

Gene sequence:

>717_bases
ATGAAAAAAAGTTTATTGCTGCTGCCAATGTTAATGGCTGCATTATCGGGGGTTGCTAATGCAGATGATTCTGCTATTCA
GCAAACCTTAAAAAAATTAGATATCCAACAAGCTGATATCCAGCCGTCACCTATCCCAGGCATTAGTACGGTGATGACCG
AAAGCGGCGTGCTCTATATCTCAGCAGATGGTAAACATCTGCTGCAAGGGCCGCTGTATGACGTGAGTGGCGATCAGCCC
ATCAATGTGACCAATCAGGCGTTGCTGAAAAAACTGGAAGCATTGAGCAGTGAAATGATTGTGTATAAAGCACCCGAGGA
AAAACACGTCATTACGGTGTTCACAGACATTACCTGCGGCTACTGCCGTAAATTGCACGAACAAATGAAAGATTATAATG
CGCTTGGCATCACTGTTCGCTATCTGGCCTTCCCGCGTCAGGGGTTAAGCTCTCAGGCGGAAAAAGACATGCGTTCTATC
TGGTGTATGGCTGATCGTAATAAAGCCTTTGATGATGCCATGAAAAATAATGATATCTCCCCAGCAACCTGCAAAACCGA
TATCAGCAAGCATTATCAGCTAGGTGTGCAATTTGGTATCCAGGGTACGCCAGCTATTGTGCTGCAAAATGGCACTATTG
TCCCAGGCTATCAGGGACCGAAAGAAATGCTACAGATGCTTAATGCGCATCAGGCTTCACTAAAAGCGGGTGGTTGA

Upstream 100 bases:

>100_bases
TCAGATTTATACGCATGTAGCGACTGAACGTTTGAGACAGCTACATCAACAGCATCATCCACGCGCTTAATCGCTGTATG
GAAAAAGATAGGATTTATAA

Downstream 100 bases:

>100_bases
TTACCTGTGACGTTGAAAACCCAACTTCGCCGCCGTGAGGCGGCAGATGACAGCCATTTACCTGCGCAATTGCCCCCGTT
ACTGCGTCGTCTCTATGCTA

Product: thiol:disulfide interchange protein DsbC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MKKSLLLLPMLMAALSGVANADDSAIQQTLKKLDIQQADIQPSPIPGISTVMTESGVLYISADGKHLLQGPLYDVSGDQP
INVTNQALLKKLEALSSEMIVYKAPEEKHVITVFTDITCGYCRKLHEQMKDYNALGITVRYLAFPRQGLSSQAEKDMRSI
WCMADRNKAFDDAMKNNDISPATCKTDISKHYQLGVQFGIQGTPAIVLQNGTIVPGYQGPKEMLQMLNAHQASLKAGG

Sequences:

>Translated_238_residues
MKKSLLLLPMLMAALSGVANADDSAIQQTLKKLDIQQADIQPSPIPGISTVMTESGVLYISADGKHLLQGPLYDVSGDQP
INVTNQALLKKLEALSSEMIVYKAPEEKHVITVFTDITCGYCRKLHEQMKDYNALGITVRYLAFPRQGLSSQAEKDMRSI
WCMADRNKAFDDAMKNNDISPATCKTDISKHYQLGVQFGIQGTPAIVLQNGTIVPGYQGPKEMLQMLNAHQASLKAGG
>Mature_238_residues
MKKSLLLLPMLMAALSGVANADDSAIQQTLKKLDIQQADIQPSPIPGISTVMTESGVLYISADGKHLLQGPLYDVSGDQP
INVTNQALLKKLEALSSEMIVYKAPEEKHVITVFTDITCGYCRKLHEQMKDYNALGITVRYLAFPRQGLSSQAEKDMRSI
WCMADRNKAFDDAMKNNDISPATCKTDISKHYQLGVQFGIQGTPAIVLQNGTIVPGYQGPKEMLQMLNAHQASLKAGG

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbC is reoxidized by a yet uncharacterized protein. Also acts as a disulfide isomerase [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1789260, Length=231, Percent_Identity=67.965367965368, Blast_Score=347, Evalue=3e-97,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10411 DsbC_N [H]

EC number: 5.3.4.1

Molecular weight: Translated: 25997; Mature: 25997

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSLLLLPMLMAALSGVANADDSAIQQTLKKLDIQQADIQPSPIPGISTVMTESGVLYI
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCHHHHHHCCCEEEE
SADGKHLLQGPLYDVSGDQPINVTNQALLKKLEALSSEMIVYKAPEEKHVITVFTDITCG
ECCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEEECCCHH
YCRKLHEQMKDYNALGITVRYLAFPRQGLSSQAEKDMRSIWCMADRNKAFDDAMKNNDIS
HHHHHHHHHHCCCCHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCC
PATCKTDISKHYQLGVQFGIQGTPAIVLQNGTIVPGYQGPKEMLQMLNAHQASLKAGG
CCHHHHHHHHHHHHHEEECCCCCCEEEEECCEEECCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKSLLLLPMLMAALSGVANADDSAIQQTLKKLDIQQADIQPSPIPGISTVMTESGVLYI
CCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCHHHHHHCCCEEEE
SADGKHLLQGPLYDVSGDQPINVTNQALLKKLEALSSEMIVYKAPEEKHVITVFTDITCG
ECCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEEECCCHH
YCRKLHEQMKDYNALGITVRYLAFPRQGLSSQAEKDMRSIWCMADRNKAFDDAMKNNDIS
HHHHHHHHHHCCCCHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCC
PATCKTDISKHYQLGVQFGIQGTPAIVLQNGTIVPGYQGPKEMLQMLNAHQASLKAGG
CCHHHHHHHHHHHHHEEECCCCCCEEEEECCEEECCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8168497 [H]