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The map label for this gene is cysH

Identifier: 51595111

GI number: 51595111

Start: 917855

End: 918589

Strand: Direct

Name: cysH

Synonym: YPTB0761

Alternate gene names: 51595111

Gene position: 917855-918589 (Clockwise)

Preceding gene: 51595110

Following gene: 51595114

Centisome position: 19.34

GC content: 50.34

Gene sequence:

>735_bases
GTGAGTCAATTTAATCTGAGCGAACTGAATGCGTTGCCGAAAGCCAAGCAAGCGGCAGCGCTGGTGCTGGTGAATGGTCA
ACTCGAGCATTTGACCGCGCAGGAGCGTGTCAGTTGGGCATTGGATAATTTGCCTGGCGAATTTGTCCTTTCCTCCAGTT
TTGGGATTCAGGCTGCGGTTTGTTTGCATCTGGTGACCCGTCAGCGTCCTGATATTCCGGTGATCTTGACCGATACCGGT
TACCTGTTCCCAGAAACATATCGTTTTATTGATGATTTGACCGAGAAGCTTCAACTTAATTTACAGGTGTTTCGTGCCGC
ACACAGCCCTGCCTGGCAGGAAGCCCGTTATGGCAAGTTATGGGAGCAGGGGGTGGAGGGTATTGAGCGTTATAACACCC
TCAATAAAGTTGAACCAATGAATCGGGCGTTGGAGGCTTTAGGTGCGCAAACCTGGTTTGCGGGTTTGCGCCGTGAGCAA
TCTGGCGGCCGCTCACAATTGCCGGTATTGGCGCTTCAGCGTGGCATATTTAAGCTGTTGCCTATTATTGATTGGGATAA
TCGCCAAGTTTATCAATACCTCACACAACATGGCCTGAGTTATCACCCACTGTGGGAGCAAGGTTACTTATCTGTCGGCG
ATACCCATACAACCCGCAAATGGGAACCGGGCATGAGTGAGGAAGAAACCCGTTTCTTTGGTCTGAAACGCGAGTGTGGT
TTGCACGAAGGTTAA

Upstream 100 bases:

>100_bases
GTCATGTCGATGAAGGTTTTGGCGATTTTGTTATTCGTGCAGGGGTCATTGCACCAGTGATTGACTCTGCCCGTGACTTT
TACGACGTACAGGAGGCGAT

Downstream 100 bases:

>100_bases
GTGTAATGTCTATGGCTCATTAAGAGGGCGCTAAGAGCGCCCCCAGACTGCTGACAAACCCCGATGACGCGATCTTGAAC
GGTGAGGATAGGCAGAGGAG

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MSQFNLSELNALPKAKQAAALVLVNGQLEHLTAQERVSWALDNLPGEFVLSSSFGIQAAVCLHLVTRQRPDIPVILTDTG
YLFPETYRFIDDLTEKLQLNLQVFRAAHSPAWQEARYGKLWEQGVEGIERYNTLNKVEPMNRALEALGAQTWFAGLRREQ
SGGRSQLPVLALQRGIFKLLPIIDWDNRQVYQYLTQHGLSYHPLWEQGYLSVGDTHTTRKWEPGMSEEETRFFGLKRECG
LHEG

Sequences:

>Translated_244_residues
MSQFNLSELNALPKAKQAAALVLVNGQLEHLTAQERVSWALDNLPGEFVLSSSFGIQAAVCLHLVTRQRPDIPVILTDTG
YLFPETYRFIDDLTEKLQLNLQVFRAAHSPAWQEARYGKLWEQGVEGIERYNTLNKVEPMNRALEALGAQTWFAGLRREQ
SGGRSQLPVLALQRGIFKLLPIIDWDNRQVYQYLTQHGLSYHPLWEQGYLSVGDTHTTRKWEPGMSEEETRFFGLKRECG
LHEG
>Mature_243_residues
SQFNLSELNALPKAKQAAALVLVNGQLEHLTAQERVSWALDNLPGEFVLSSSFGIQAAVCLHLVTRQRPDIPVILTDTGY
LFPETYRFIDDLTEKLQLNLQVFRAAHSPAWQEARYGKLWEQGVEGIERYNTLNKVEPMNRALEALGAQTWFAGLRREQS
GGRSQLPVLALQRGIFKLLPIIDWDNRQVYQYLTQHGLSYHPLWEQGYLSVGDTHTTRKWEPGMSEEETRFFGLKRECGL
HEG

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=244, Percent_Identity=77.8688524590164, Blast_Score=411, Evalue=1e-116,
Organism=Saccharomyces cerevisiae, GI6325425, Length=245, Percent_Identity=29.7959183673469, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR011800
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 27852; Mature: 27721

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQFNLSELNALPKAKQAAALVLVNGQLEHLTAQERVSWALDNLPGEFVLSSSFGIQAAV
CCCCCHHHHHCCCCHHHCEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHH
CLHLVTRQRPDIPVILTDTGYLFPETYRFIDDLTEKLQLNLQVFRAAHSPAWQEARYGKL
HHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
WEQGVEGIERYNTLNKVEPMNRALEALGAQTWFAGLRREQSGGRSQLPVLALQRGIFKLL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
PIIDWDNRQVYQYLTQHGLSYHPLWEQGYLSVGDTHTTRKWEPGMSEEETRFFGLKRECG
CCCCCCCHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCHHHHHCCHHHCC
LHEG
CCCC
>Mature Secondary Structure 
SQFNLSELNALPKAKQAAALVLVNGQLEHLTAQERVSWALDNLPGEFVLSSSFGIQAAV
CCCCHHHHHCCCCHHHCEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHH
CLHLVTRQRPDIPVILTDTGYLFPETYRFIDDLTEKLQLNLQVFRAAHSPAWQEARYGKL
HHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
WEQGVEGIERYNTLNKVEPMNRALEALGAQTWFAGLRREQSGGRSQLPVLALQRGIFKLL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
PIIDWDNRQVYQYLTQHGLSYHPLWEQGYLSVGDTHTTRKWEPGMSEEETRFFGLKRECG
CCCCCCCHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCHHHHHCCHHHCC
LHEG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA