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The map label for this gene is orn

Identifier: 51594770

GI number: 51594770

Start: 499320

End: 499865

Strand: Direct

Name: orn

Synonym: YPTB0418

Alternate gene names: 51594770

Gene position: 499320-499865 (Clockwise)

Preceding gene: 51594766

Following gene: 51594772

Centisome position: 10.52

GC content: 46.7

Gene sequence:

>546_bases
ATGGCAGAAAATCAAAATAATCTGATCTGGATCGATCTGGAAATGACCGGTCTCGATCCAGAGCGGGATCGCATCATCGA
AATCGCTACCTTGGTCACTGATGCGAATCTTAATATTCTGGCAGAAGGACCTGTTCTGGCAGTCCATCAATCTGCTGAAC
AGCTTGGGCTAATGGATGAGTGGAATGTTCGTACCCATACTGGTAGTGGCTTGGTTGAGCGGGTGAAAACCAGCCCCTTT
AATGACCGTGATGCTGAATTACAAACTATCGAATTCCTAAAACAGTGGGTCCCCGCGGGGGTTTCACCCATTTGCGGTAA
CAGTGTAGGTCAGGACCGCCGTTTCCTGTTCCGCTACATGCCAGAGCTTGAAGCGTATTTCCATTACCGCTATGTAGATG
TCAGTACATTGAAAGAGTTAGCGCGTCGCTGGAAACCTGAAATTCTGGCTGGTTTTAAAAAGCAAAATACCCATCAGGCA
TTGGATGACATTCGTGAGTCAGTCGCCGAGCTTGCTTACTATCGTGAGCATTTTATTCAATCTTAA

Upstream 100 bases:

>100_bases
GGATATATCGCTCGTTGCGACCAAAAGGACTATGATACACATTATTTTATTAATTAACCGTTTGTTCGGTTGCTCCCCCG
GCTTACAGATAGGAAATATC

Downstream 100 bases:

>100_bases
TTCCCTTCGGCCTTGAAACAGCAGGGGCGTTAGCTGCGCGCACTTACCCGAATCACTTACTGATGTAAGCTCATCGGGAC
GCGTTTGCTTGCTGCCTGCC

Product: oligoribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MAENQNNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGPVLAVHQSAEQLGLMDEWNVRTHTGSGLVERVKTSPF
NDRDAELQTIEFLKQWVPAGVSPICGNSVGQDRRFLFRYMPELEAYFHYRYVDVSTLKELARRWKPEILAGFKKQNTHQA
LDDIRESVAELAYYREHFIQS

Sequences:

>Translated_181_residues
MAENQNNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGPVLAVHQSAEQLGLMDEWNVRTHTGSGLVERVKTSPF
NDRDAELQTIEFLKQWVPAGVSPICGNSVGQDRRFLFRYMPELEAYFHYRYVDVSTLKELARRWKPEILAGFKKQNTHQA
LDDIRESVAELAYYREHFIQS
>Mature_180_residues
AENQNNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGPVLAVHQSAEQLGLMDEWNVRTHTGSGLVERVKTSPFN
DRDAELQTIEFLKQWVPAGVSPICGNSVGQDRRFLFRYMPELEAYFHYRYVDVSTLKELARRWKPEILAGFKKQNTHQAL
DDIRESVAELAYYREHFIQS

Specific function: 3'-to-5' exoribonuclease specific for small oligoribonucleotides

COG id: COG1949

COG function: function code A; Oligoribonuclease (3'->5' exoribonuclease)

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain

Homologues:

Organism=Homo sapiens, GI224496106, Length=169, Percent_Identity=50.2958579881657, Blast_Score=177, Evalue=3e-45,
Organism=Escherichia coli, GI87082382, Length=180, Percent_Identity=86.1111111111111, Blast_Score=333, Evalue=6e-93,
Organism=Caenorhabditis elegans, GI17557752, Length=178, Percent_Identity=48.314606741573, Blast_Score=169, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6323088, Length=187, Percent_Identity=36.8983957219251, Blast_Score=121, Evalue=6e-29,
Organism=Drosophila melanogaster, GI21355135, Length=175, Percent_Identity=46.8571428571429, Blast_Score=183, Evalue=4e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ORN_YERP3 (A7FMY7)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001402615.1
- ProteinModelPortal:   A7FMY7
- SMR:   A7FMY7
- STRING:   A7FMY7
- GeneID:   5385844
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_3661
- eggNOG:   COG1949
- HOGENOM:   HBG448545
- OMA:   WNKGTHG
- ProtClustDB:   PRK05359
- BioCyc:   YPSE349747:YPSIP31758_3661-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00045
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR022894
- InterPro:   IPR012337
- SMART:   SM00479

Pfam domain/function: PF00929 Exonuc_X-T; SSF53098 RNaseH_fold

EC number: 3.1.-.- [C]

Molecular weight: Translated: 20906; Mature: 20775

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: ACT_SITE 129-129

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAENQNNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGPVLAVHQSAEQLGLMDE
CCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCEEEEECCHHHCCCCCC
WNVRTHTGSGLVERVKTSPFNDRDAELQTIEFLKQWVPAGVSPICGNSVGQDRRFLFRYM
CCCEEECCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
PELEAYFHYRYVDVSTLKELARRWKPEILAGFKKQNTHQALDDIRESVAELAYYREHFIQ
HHHHHHHHHEEECHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
S
C
>Mature Secondary Structure 
AENQNNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGPVLAVHQSAEQLGLMDE
CCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCEEEEECCHHHCCCCCC
WNVRTHTGSGLVERVKTSPFNDRDAELQTIEFLKQWVPAGVSPICGNSVGQDRRFLFRYM
CCCEEECCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
PELEAYFHYRYVDVSTLKELARRWKPEILAGFKKQNTHQALDDIRESVAELAYYREHFIQ
HHHHHHHHHEEECHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA