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The map label for this gene is hmuS

Identifier: 51594694

GI number: 51594694

Start: 404072

End: 405109

Strand: Reverse

Name: hmuS

Synonym: YPTB0339

Alternate gene names: 51594694

Gene position: 405109-404072 (Counterclockwise)

Preceding gene: 51594695

Following gene: 51594693

Centisome position: 8.54

GC content: 50.58

Gene sequence:

>1038_bases
ATGAACGCATCATTATACCAACAATATGTACAGGCTAAAGCAGAGCACCCTGGCAAATATGCCCGTGATTTAGCCACCCT
GATGGGGATTTCAGAAGCAGAGCTGACCCACAGCCGCGTCGGGCATGATGCAAAACGTTTACAAAGTGATGCTCGTGCAT
TATTGGCCGCATTGGAATCCGTCGGCGAAGTCAAAGCCATTACCCGCAACACCTATGCAGTTCATGAGCAAGTGGGCCGC
TATGAGAACCAACACTTAAATGGTCATGCAGGGTTAATCCTCAATCCACGCGCCTTGGACCTCCGGTTATTCCTGAATCA
GTGGGCAAGCGCCTTTACACTGACCGAAGAGACCCGCCACGGCGTGCGCCATAGCATCCAATTTTTCGACCATCAGGGCG
ATGCATTACACAAAGTGTATGTGACAGAACAGACAGATATGTCTGCCTGGGAAGCCTTGCTGGCACAATTTATCATCCCG
GAAAACCCGGCATTGCAGTTAGAACCTTTGAGCACCCCAGAAGCGGTAGAACCTACAGCCGATGATGCAACCGTGGATAG
CGAATGGCGTGCCATGACCGATGTACACCAGTTCTTCCAACTGCTTAAACGCAATAATCTGACCCGTCAGCAGGCGTTCC
GCGCTGTTGGTGATGATCTGGCTTACCAGGTCGATAACAACTCACTGACTCAGCTGTTGCACATCGCCCAGCAAGATCAG
AACGAGATCATGATTTTTGTCGGCAACCGCGGCTGTGTACAAATTTTCACCGGCCTGATTGAAAAAGTCACACCACACAA
CGAATGGATTAATGTCTTCAATCAGCGCTTTACACTGCATCTGATCGAAACGGCCATTGCCGAAAGCTGGATCACCCGCA
AACCAACAAAAGACGGTTTTGTCACCAGCCTAGAACTGTTTGCTGCTGATGGTACTCAACTTGCCCAACTCTACGGCCAG
CGCACCGAAGGGCAGCCAGAACAAAACCAATGGCGTGAACAGATTGCCCGCCTAATCAACAAGGATATCGCCGCATGA

Upstream 100 bases:

>100_bases
TCTGAAATCATTCATCCGGTAATCCATTTTGTGGCTTGCCGGATTATCATTTGACAATGATTACCTGCATACAAAAAAAC
CAATTAATTAGGAAGCCATT

Downstream 100 bases:

>100_bases
GACTCCGGTTGCTGTCGCTCCCCTTAATTCTGTCGCTCTGTGCCCCTCTGCTGCCACTAAATACCTTGGCGGCAGAACGT
ATTGTGACTATTGGTGGAGA

Product: hemin degradation/transport protein hmuS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MNASLYQQYVQAKAEHPGKYARDLATLMGISEAELTHSRVGHDAKRLQSDARALLAALESVGEVKAITRNTYAVHEQVGR
YENQHLNGHAGLILNPRALDLRLFLNQWASAFTLTEETRHGVRHSIQFFDHQGDALHKVYVTEQTDMSAWEALLAQFIIP
ENPALQLEPLSTPEAVEPTADDATVDSEWRAMTDVHQFFQLLKRNNLTRQQAFRAVGDDLAYQVDNNSLTQLLHIAQQDQ
NEIMIFVGNRGCVQIFTGLIEKVTPHNEWINVFNQRFTLHLIETAIAESWITRKPTKDGFVTSLELFAADGTQLAQLYGQ
RTEGQPEQNQWREQIARLINKDIAA

Sequences:

>Translated_345_residues
MNASLYQQYVQAKAEHPGKYARDLATLMGISEAELTHSRVGHDAKRLQSDARALLAALESVGEVKAITRNTYAVHEQVGR
YENQHLNGHAGLILNPRALDLRLFLNQWASAFTLTEETRHGVRHSIQFFDHQGDALHKVYVTEQTDMSAWEALLAQFIIP
ENPALQLEPLSTPEAVEPTADDATVDSEWRAMTDVHQFFQLLKRNNLTRQQAFRAVGDDLAYQVDNNSLTQLLHIAQQDQ
NEIMIFVGNRGCVQIFTGLIEKVTPHNEWINVFNQRFTLHLIETAIAESWITRKPTKDGFVTSLELFAADGTQLAQLYGQ
RTEGQPEQNQWREQIARLINKDIAA
>Mature_345_residues
MNASLYQQYVQAKAEHPGKYARDLATLMGISEAELTHSRVGHDAKRLQSDARALLAALESVGEVKAITRNTYAVHEQVGR
YENQHLNGHAGLILNPRALDLRLFLNQWASAFTLTEETRHGVRHSIQFFDHQGDALHKVYVTEQTDMSAWEALLAQFIIP
ENPALQLEPLSTPEAVEPTADDATVDSEWRAMTDVHQFFQLLKRNNLTRQQAFRAVGDDLAYQVDNNSLTQLLHIAQQDQ
NEIMIFVGNRGCVQIFTGLIEKVTPHNEWINVFNQRFTLHLIETAIAESWITRKPTKDGFVTSLELFAADGTQLAQLYGQ
RTEGQPEQNQWREQIARLINKDIAA

Specific function: Part of the binding-protein-dependent transport system for hemin

COG id: COG3720

COG function: function code P; Putative heme degradation protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To Y.enterocolitica hemS

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HMUS_YERPE (Q56990)

Other databases:

- EMBL:   U60647
- EMBL:   AL590842
- EMBL:   AE009952
- EMBL:   AE017042
- PIR:   AF0035
- PIR:   T12070
- RefSeq:   NP_667879.1
- RefSeq:   NP_991831.1
- RefSeq:   YP_002345364.1
- ProteinModelPortal:   Q56990
- SMR:   Q56990
- IntAct:   Q56990
- GeneID:   1145489
- GeneID:   1173128
- GeneID:   2764262
- GenomeReviews:   AE009952_GR
- GenomeReviews:   AE017042_GR
- GenomeReviews:   AL590842_GR
- KEGG:   ype:YPO0282
- KEGG:   ypk:y0542
- KEGG:   ypm:YP_0437
- HOGENOM:   HBG391237
- OMA:   LPIMCFV
- ProtClustDB:   CLSK863184
- BioCyc:   YPES187410:Y0542-MONOMER
- BioCyc:   YPES214092:YPO0282-MONOMER
- InterPro:   IPR007845

Pfam domain/function: PF05171 HemS

EC number: NA

Molecular weight: Translated: 39091; Mature: 39091

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNASLYQQYVQAKAEHPGKYARDLATLMGISEAELTHSRVGHDAKRLQSDARALLAALES
CCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
VGEVKAITRNTYAVHEQVGRYENQHLNGHAGLILNPRALDLRLFLNQWASAFTLTEETRH
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHH
GVRHSIQFFDHQGDALHKVYVTEQTDMSAWEALLAQFIIPENPALQLEPLSTPEAVEPTA
HHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCC
DDATVDSEWRAMTDVHQFFQLLKRNNLTRQQAFRAVGDDLAYQVDNNSLTQLLHIAQQDQ
CCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHEEEECCHHHHHHHHHHHCCC
NEIMIFVGNRGCVQIFTGLIEKVTPHNEWINVFNQRFTLHLIETAIAESWITRKPTKDGF
CCEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
VTSLELFAADGTQLAQLYGQRTEGQPEQNQWREQIARLINKDIAA
HHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNASLYQQYVQAKAEHPGKYARDLATLMGISEAELTHSRVGHDAKRLQSDARALLAALES
CCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHH
VGEVKAITRNTYAVHEQVGRYENQHLNGHAGLILNPRALDLRLFLNQWASAFTLTEETRH
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHH
GVRHSIQFFDHQGDALHKVYVTEQTDMSAWEALLAQFIIPENPALQLEPLSTPEAVEPTA
HHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCC
DDATVDSEWRAMTDVHQFFQLLKRNNLTRQQAFRAVGDDLAYQVDNNSLTQLLHIAQQDQ
CCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHEEEECCHHHHHHHHHHHCCC
NEIMIFVGNRGCVQIFTGLIEKVTPHNEWINVFNQRFTLHLIETAIAESWITRKPTKDGF
CCEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
VTSLELFAADGTQLAQLYGQRTEGQPEQNQWREQIARLINKDIAA
HHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9026634; 11586360; 12142430