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The map label for this gene is xseA

Identifier: 50842055

GI number: 50842055

Start: 628653

End: 629900

Strand: Reverse

Name: xseA

Synonym: PPA0569

Alternate gene names: 50842055

Gene position: 629900-628653 (Counterclockwise)

Preceding gene: 50842056

Following gene: 50842054

Centisome position: 24.6

GC content: 63.14

Gene sequence:

>1248_bases
ATGGTCGAGCCGAACGCCGCCGACAATCCGCGCTCCCTGGCGTGGGTCGTCAACGCCGTCAAGGGGTGGGTAGAGCGCTG
CGGAGCCATCTGGGTGCAAGCCCAGGTAATCGAGATCACCAGGCGCTCCAGTCCGACACAGTTCCTCACCCTGCGCGACC
CCATCGAGGAGATTTCGGCCAGCGCCACCTGCCATCGCAGGGTCCTCGACGCCGCCGGACCAATCGAGACGGGCATGACG
GTTACCGCCCTCATCCGACCGACAGTGTGGTCGCGCACTGGGAGGCTCTCCTTCGAAATCTCCGAGATCACCCCCACCGG
TGAGGGCCAGCTCCTCGCCCAACTAGAGAGACGCAAACGACTTCTCGAGGCTGAAGGGCTCTTCGATGTCACCCTCCATA
GGCCGATTCCCGTTTTGCCCCGCGGCATCGGTCTCATCACCGGAGCTGGCTCCGATGCTGAACGTGACGTCCAGCGTCAT
GCCACGTTGCGCTGGCCTGCCGCCCGATTCGTCGTCCACAACACCCGGGTACAGGGCCCCATGGCGGCCCAACAGATCAT
CGCCGCCCTCGCTGACCTTGACGCCGACCCCACCGTCGATGTCATCGTCATTGCCCGCGGTGGTGGCCCCTTGGAAGACC
TCCTCCCCTTCAGCGACGAAGCTCTGGTGAGAGCGGTTTACGCCACCCGGACTCCCGTCGTTTCGGCCATCGGTCATGAC
CGTGACAATCCGATTCTCGATCTCGTCGCTGACCTACGCGCGTCGACGCCCACTGACGCGGGCAAGCTCATCGTCCCGGA
TGCTGCTGAGCAGTCCCAAGCTATCGAGACAGCCAGAGCTCAACTTCGCCAGGCCGTTACGAGGTTCATCGACGTCGAAA
GCGGACACCTCTCTCAGATCCGCTCCCGCCCAGTAATGGTCAATCCAGCAGCCACTCTCGATATCGCGGTAGAAAGGCTC
GACTCCACACTGCAACGTCTACGTCTTGCTACTCACCGCGTCCTGGACGCCGAGAGCCGCGACGTCAACCACATGCTTGA
GCGCGTGCGAGCAATGTCGCCCAAGGCCACCTTGGATCGCGGCTACGCCATCCTCGCCGACACGGAGGGCGACTCCATCA
CCTCAGTCAATGACACCAACGCACGCGCGAACCTATTGGTCTACCTGTCTGACGGTACCCTCAGCGTCACCGTCGATTCT
CTCGACCGCCGCACCCCAAACCGTCCCACCTTCCAGGAGGACTCATGA

Upstream 100 bases:

>100_bases
TTCCGCGCACTGGAGTGTGATCGTTTGAGGAGTTCGGGCCGCTGCCTGTTATGGTGACGGCCCGACGCTTCTGTCGTCAT
TGTTGGCTAGCGTAGTGCCC

Downstream 100 bases:

>100_bases
CCGACACTACCCCGAACTCAGCTCCCGAGGAACCGGAAATCACCTACGAGGCTGCACGCGACGAACTAGTCGAAATCGTC
ACCCGGCTCGAATCCGGTGG

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MVEPNAADNPRSLAWVVNAVKGWVERCGAIWVQAQVIEITRRSSPTQFLTLRDPIEEISASATCHRRVLDAAGPIETGMT
VTALIRPTVWSRTGRLSFEISEITPTGEGQLLAQLERRKRLLEAEGLFDVTLHRPIPVLPRGIGLITGAGSDAERDVQRH
ATLRWPAARFVVHNTRVQGPMAAQQIIAALADLDADPTVDVIVIARGGGPLEDLLPFSDEALVRAVYATRTPVVSAIGHD
RDNPILDLVADLRASTPTDAGKLIVPDAAEQSQAIETARAQLRQAVTRFIDVESGHLSQIRSRPVMVNPAATLDIAVERL
DSTLQRLRLATHRVLDAESRDVNHMLERVRAMSPKATLDRGYAILADTEGDSITSVNDTNARANLLVYLSDGTLSVTVDS
LDRRTPNRPTFQEDS

Sequences:

>Translated_415_residues
MVEPNAADNPRSLAWVVNAVKGWVERCGAIWVQAQVIEITRRSSPTQFLTLRDPIEEISASATCHRRVLDAAGPIETGMT
VTALIRPTVWSRTGRLSFEISEITPTGEGQLLAQLERRKRLLEAEGLFDVTLHRPIPVLPRGIGLITGAGSDAERDVQRH
ATLRWPAARFVVHNTRVQGPMAAQQIIAALADLDADPTVDVIVIARGGGPLEDLLPFSDEALVRAVYATRTPVVSAIGHD
RDNPILDLVADLRASTPTDAGKLIVPDAAEQSQAIETARAQLRQAVTRFIDVESGHLSQIRSRPVMVNPAATLDIAVERL
DSTLQRLRLATHRVLDAESRDVNHMLERVRAMSPKATLDRGYAILADTEGDSITSVNDTNARANLLVYLSDGTLSVTVDS
LDRRTPNRPTFQEDS
>Mature_415_residues
MVEPNAADNPRSLAWVVNAVKGWVERCGAIWVQAQVIEITRRSSPTQFLTLRDPIEEISASATCHRRVLDAAGPIETGMT
VTALIRPTVWSRTGRLSFEISEITPTGEGQLLAQLERRKRLLEAEGLFDVTLHRPIPVLPRGIGLITGAGSDAERDVQRH
ATLRWPAARFVVHNTRVQGPMAAQQIIAALADLDADPTVDVIVIARGGGPLEDLLPFSDEALVRAVYATRTPVVSAIGHD
RDNPILDLVADLRASTPTDAGKLIVPDAAEQSQAIETARAQLRQAVTRFIDVESGHLSQIRSRPVMVNPAATLDIAVERL
DSTLQRLRLATHRVLDAESRDVNHMLERVRAMSPKATLDRGYAILADTEGDSITSVNDTNARANLLVYLSDGTLSVTVDS
LDRRTPNRPTFQEDS

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=422, Percent_Identity=26.5402843601896, Blast_Score=154, Evalue=9e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 45307; Mature: 45307

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEPNAADNPRSLAWVVNAVKGWVERCGAIWVQAQVIEITRRSSPTQFLTLRDPIEEISA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEHEEEEEHHCCCCCEEEEECCCHHHHHH
SATCHRRVLDAAGPIETGMTVTALIRPTVWSRTGRLSFEISEITPTGEGQLLAQLERRKR
HHHHHHHHHHCCCCCCCCCEEEEEECCHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHH
LLEAEGLFDVTLHRPIPVLPRGIGLITGAGSDAERDVQRHATLRWPAARFVVHNTRVQGP
HHHHCCCEEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHCCCCCHHEEEEECCCCCCH
MAAQQIIAALADLDADPTVDVIVIARGGGPLEDLLPFSDEALVRAVYATRTPVVSAIGHD
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHCCCCHHHHHHHHHHHCCCHHHHHCCC
RDNPILDLVADLRASTPTDAGKLIVPDAAEQSQAIETARAQLRQAVTRFIDVESGHLSQI
CCCHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
RSRPVMVNPAATLDIAVERLDSTLQRLRLATHRVLDAESRDVNHMLERVRAMSPKATLDR
HCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHCC
GYAILADTEGDSITSVNDTNARANLLVYLSDGTLSVTVDSLDRRTPNRPTFQEDS
CEEEEEECCCCCEEECCCCCCCEEEEEEEECCEEEEEECCHHCCCCCCCCCCCCC
>Mature Secondary Structure
MVEPNAADNPRSLAWVVNAVKGWVERCGAIWVQAQVIEITRRSSPTQFLTLRDPIEEISA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEHEEEEEHHCCCCCEEEEECCCHHHHHH
SATCHRRVLDAAGPIETGMTVTALIRPTVWSRTGRLSFEISEITPTGEGQLLAQLERRKR
HHHHHHHHHHCCCCCCCCCEEEEEECCHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHH
LLEAEGLFDVTLHRPIPVLPRGIGLITGAGSDAERDVQRHATLRWPAARFVVHNTRVQGP
HHHHCCCEEEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHCCCCCHHEEEEECCCCCCH
MAAQQIIAALADLDADPTVDVIVIARGGGPLEDLLPFSDEALVRAVYATRTPVVSAIGHD
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHCCCCHHHHHHHHHHHCCCHHHHHCCC
RDNPILDLVADLRASTPTDAGKLIVPDAAEQSQAIETARAQLRQAVTRFIDVESGHLSQI
CCCHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
RSRPVMVNPAATLDIAVERLDSTLQRLRLATHRVLDAESRDVNHMLERVRAMSPKATLDR
HCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHCC
GYAILADTEGDSITSVNDTNARANLLVYLSDGTLSVTVDSLDRRTPNRPTFQEDS
CEEEEEECCCCCEEECCCCCCCEEEEEEEECCEEEEEECCHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA