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The map label for this gene is cobI [H]

Identifier: 50841903

GI number: 50841903

Start: 463846

End: 464601

Strand: Direct

Name: cobI [H]

Synonym: PPA0420

Alternate gene names: 50841903

Gene position: 463846-464601 (Clockwise)

Preceding gene: 50841902

Following gene: 50841904

Centisome position: 18.12

GC content: 62.57

Gene sequence:

>756_bases
ATGAACGATGCCACGTCACGCACGCTTTTCGGAGTGGGAGTCGGCCCGGGCGACCCGGAACTGGTCACCGTGAAAACCGT
ACGCATCTTGCGCGAGGCAGACGTGATCCTCGTTCCCTACACCGAGGCCACCACTGATGGTCCGGGGCGTGCCGAGAGCA
TCGTCACAGCTGTCGCCCCCGAGATCGCCGGGCGTATCAGACGCATCCCCTTCTCAATGCGGGAGAGGTCCGGTGTCGGT
GAAAAGCGCAAGGCCTCCTGGCAGGTCTCCTCCGACGCCGTGGTTACAGCTTTTGATGAGGGAGCCCGTACCGTCGCCCT
TGCCACCGTCGGTGATCCGACTGTTTTCTCTACCTTCACCTATCTGCGTGCCAACGTTGAGGAGAGGCTGCCCGACGTCA
CCGTCGAGTTGAGCCCTGGCATTACCGCCATGCAGGCCCTGTCGGCTGCATCCGGGCGTCCACTCGTCGAGGGCAAGGAG
ATCCTGGCCCTCGTCCCGGCTACCGTCGGCATCAGCAAACTTGGGCAGGTCCTCGACCTCGTTGACTCGGTTGCGATCTA
CAAGGGCGGACGTAAACTCCCCGACGTCGTCGAGCAGTTGCGCAGCCGGGACCGTCAGGCTGTCATCGGCACCGACGTCA
CCTTGGAATCCGAGCAGATCATCACCCTTGACGAAGTGGCTGACGCGCAGACTCTGCCGTATTTCTCGACCGTCTTGACC
ACTCCGGAGCGCACCACCACAGGAGGGAAACTGTGA

Upstream 100 bases:

>100_bases
GCGGTCCCGCCACTGTGAGACACCCCATGCGGTGCAGCCAGACGCTCTGCCCGGTTCCTGCCGAACAAACCGTCAGGCGA
GGGTACCTGAGGAGAACCAC

Downstream 100 bases:

>100_bases
GCGAACCTCAGGCCGCACGGCCCACCCAGCATGTGTCTGAGAAGGCTCTGGAGGATTTAGACCACAACGTCATCGAGCCG
CCGCCGGTGCCCCGTCGTGA

Product: tetrapyrrole methylase, putative precorrin-2 C20-methyltransferase, CbiL

Products: NA

Alternate protein names: S-adenosyl-L-methionine--precorrin-2 methyltransferase; SP2MT [H]

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MNDATSRTLFGVGVGPGDPELVTVKTVRILREADVILVPYTEATTDGPGRAESIVTAVAPEIAGRIRRIPFSMRERSGVG
EKRKASWQVSSDAVVTAFDEGARTVALATVGDPTVFSTFTYLRANVEERLPDVTVELSPGITAMQALSAASGRPLVEGKE
ILALVPATVGISKLGQVLDLVDSVAIYKGGRKLPDVVEQLRSRDRQAVIGTDVTLESEQIITLDEVADAQTLPYFSTVLT
TPERTTTGGKL

Sequences:

>Translated_251_residues
MNDATSRTLFGVGVGPGDPELVTVKTVRILREADVILVPYTEATTDGPGRAESIVTAVAPEIAGRIRRIPFSMRERSGVG
EKRKASWQVSSDAVVTAFDEGARTVALATVGDPTVFSTFTYLRANVEERLPDVTVELSPGITAMQALSAASGRPLVEGKE
ILALVPATVGISKLGQVLDLVDSVAIYKGGRKLPDVVEQLRSRDRQAVIGTDVTLESEQIITLDEVADAQTLPYFSTVLT
TPERTTTGGKL
>Mature_251_residues
MNDATSRTLFGVGVGPGDPELVTVKTVRILREADVILVPYTEATTDGPGRAESIVTAVAPEIAGRIRRIPFSMRERSGVG
EKRKASWQVSSDAVVTAFDEGARTVALATVGDPTVFSTFTYLRANVEERLPDVTVELSPGITAMQALSAASGRPLVEGKE
ILALVPATVGISKLGQVLDLVDSVAIYKGGRKLPDVVEQLRSRDRQAVIGTDVTLESEQIITLDEVADAQTLPYFSTVLT
TPERTTTGGKL

Specific function: Methylates precorrin-2 at the C-20 position to produce precorrin-3A [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.130 [H]

Molecular weight: Translated: 26723; Mature: 26723

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDATSRTLFGVGVGPGDPELVTVKTVRILREADVILVPYTEATTDGPGRAESIVTAVAP
CCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHHH
EIAGRIRRIPFSMRERSGVGEKRKASWQVSSDAVVTAFDEGARTVALATVGDPTVFSTFT
HHHHHHHCCCCHHHHHCCCCCCCCCCEEECCCEEEEEECCCCEEEEEEECCCCHHHHHHH
YLRANVEERLPDVTVELSPGITAMQALSAASGRPLVEGKEILALVPATVGISKLGQVLDL
HHHHCHHHHCCCEEEEECCCHHHHHHHHHCCCCCCCCCCEEEEEECCHHCHHHHHHHHHH
VDSVAIYKGGRKLPDVVEQLRSRDRQAVIGTDVTLESEQIITLDEVADAQTLPYFSTVLT
HHHHHHHCCCCCCHHHHHHHHCCCCEEEECCCEEECCCCEEEHHHHCCCCCCCHHHHHCC
TPERTTTGGKL
CCCCCCCCCCC
>Mature Secondary Structure
MNDATSRTLFGVGVGPGDPELVTVKTVRILREADVILVPYTEATTDGPGRAESIVTAVAP
CCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHHH
EIAGRIRRIPFSMRERSGVGEKRKASWQVSSDAVVTAFDEGARTVALATVGDPTVFSTFT
HHHHHHHCCCCHHHHHCCCCCCCCCCEEECCCEEEEEECCCCEEEEEEECCCCHHHHHHH
YLRANVEERLPDVTVELSPGITAMQALSAASGRPLVEGKEILALVPATVGISKLGQVLDL
HHHHCHHHHCCCEEEEECCCHHHHHHHHHCCCCCCCCCCEEEEEECCHHCHHHHHHHHHH
VDSVAIYKGGRKLPDVVEQLRSRDRQAVIGTDVTLESEQIITLDEVADAQTLPYFSTVLT
HHHHHHHCCCCCCHHHHHHHHCCCCEEEECCCEEECCCCEEEHHHHCCCCCCCHHHHHCC
TPERTTTGGKL
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521 [H]