BacMap

Definition	Propionibacterium acnes KPA171202, complete genome.
Accession	NC_006085
Length	2,560,265

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The map label for this gene is yqjQ [H]

Identifier: 50841816

GI number: 50841816

Start: 380112

End: 380906

Strand: Reverse

Name: yqjQ [H]

Synonym: PPA0330

Alternate gene names: 50841816

Gene position: 380906-380112 (Counterclockwise)

Preceding gene: 50841817

Following gene: 50841801

Centisome position: 14.88

GC content: 62.89

Gene sequence:

>795_bases
ATGAATGACATGGAGGCGACTCGCGACGAACGCCCGTGGGCACTGGTGAGCGGGGCCAGTGGTGGTCTAGGGCAGGCATT
TAGCCGCCATCTGGCCAGCTGCGGCGTCAACCTCGTTGTGACCGGACGGCGGCATGACGTCCTCGACGACCTCGCCGACC
AGCTCACCACCAGGTACGGAATCCAAACTATCGTTCATCCCTGCGACATCTCCTCGGCATCAGAGCGGTTAGCCCTTGTC
AACGAGATTGCGGGACGCGGGATCATCATCGACACCCTCGTCAACAATGCTGGATTCGGTGCTGCTGGCCGCATCGCTGA
GACCGACCCGGAGCGTCAAACCTCCCAGGTAGAGGTCAACTGCGAGGCTGTCGTGCACCTGTGTGGGTTACTGCTGCCTG
GCATGATCACAGCCAAACGTGGGTCGATTATCAATGTCGCCTCTACTGCGGCTTTCCAGCCCATTCCACAGTTCGCCACC
TACGCGGCATCGAAGTCCTTCGTGCTGTCCTTCACCCGTGCCCTATGGGCTGAGACCAATGGCACCGGGGTGCGCGCCAC
CGCGATCTGCCCTGGTCCCACCGAAACCGGGTTCTTCGACGTCGCCGGGGTACCGCGTATGGCGGCCGGTGCTCGGCGCG
ACCCAGACGACGTGGTCCGTACCGCCTTCGACGCTCTAGCCCGTCATCGCCCCTACGCCGTTGACGGTTTCGTTAACCGC
ACCGTCGCGCGGCTGGCGCCACATCTACCGGCGCGGCTGGTGATGACTCAAGCCGAGAAATACCTCCAGGTCTGA

Upstream 100 bases:

>100_bases
CAGACAGCCCTACCAAGACCCACGCGCACTACAGACGATTGGGCACCCCGAACTCACCTGCGCAGCATGCACTCCGGTGA
CAGCGTGGAAGACTTGAAAC

Downstream 100 bases:

>100_bases
AGCCAACGCACCTACTTGGCCGTGATGACCTTCTCGTCGGCGATGTGGGTTCCCTCGCGGATGATTAAGTCGTATTCCCC
TTTCGGCATGGTGAAGGTGG

Product: putative short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MNDMEATRDERPWALVSGASGGLGQAFSRHLASCGVNLVVTGRRHDVLDDLADQLTTRYGIQTIVHPCDISSASERLALV
NEIAGRGIIIDTLVNNAGFGAAGRIAETDPERQTSQVEVNCEAVVHLCGLLLPGMITAKRGSIINVASTAAFQPIPQFAT
YAASKSFVLSFTRALWAETNGTGVRATAICPGPTETGFFDVAGVPRMAAGARRDPDDVVRTAFDALARHRPYAVDGFVNR
TVARLAPHLPARLVMTQAEKYLQV

Sequences:

>Translated_264_residues
MNDMEATRDERPWALVSGASGGLGQAFSRHLASCGVNLVVTGRRHDVLDDLADQLTTRYGIQTIVHPCDISSASERLALV
NEIAGRGIIIDTLVNNAGFGAAGRIAETDPERQTSQVEVNCEAVVHLCGLLLPGMITAKRGSIINVASTAAFQPIPQFAT
YAASKSFVLSFTRALWAETNGTGVRATAICPGPTETGFFDVAGVPRMAAGARRDPDDVVRTAFDALARHRPYAVDGFVNR
TVARLAPHLPARLVMTQAEKYLQV
>Mature_264_residues
MNDMEATRDERPWALVSGASGGLGQAFSRHLASCGVNLVVTGRRHDVLDDLADQLTTRYGIQTIVHPCDISSASERLALV
NEIAGRGIIIDTLVNNAGFGAAGRIAETDPERQTSQVEVNCEAVVHLCGLLLPGMITAKRGSIINVASTAAFQPIPQFAT
YAASKSFVLSFTRALWAETNGTGVRATAICPGPTETGFFDVAGVPRMAAGARRDPDDVVRTAFDALARHRPYAVDGFVNR
TVARLAPHLPARLVMTQAEKYLQV

Specific function: Unknown

COG id: COG0300

COG function: function code R; Short-chain dehydrogenases of various substrate specificities

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI226371731, Length=181, Percent_Identity=30.3867403314917, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI7705855, Length=250, Percent_Identity=24.8, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4557649, Length=192, Percent_Identity=28.6458333333333, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI20149619, Length=189, Percent_Identity=30.1587301587302, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI32483357, Length=186, Percent_Identity=30.1075268817204, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI7706318, Length=189, Percent_Identity=28.042328042328, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI210032110, Length=243, Percent_Identity=26.3374485596708, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI5031737, Length=189, Percent_Identity=29.6296296296296, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=29.6296296296296, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI40807363, Length=243, Percent_Identity=21.8106995884774, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI109715829, Length=203, Percent_Identity=30.0492610837438, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI40254992, Length=181, Percent_Identity=27.6243093922652, Blast_Score=65, Evalue=9e-11,
Organism=Homo sapiens, GI31542939, Length=193, Percent_Identity=28.4974093264249, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1787820, Length=179, Percent_Identity=31.8435754189944, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI87082100, Length=189, Percent_Identity=31.2169312169312, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787335, Length=190, Percent_Identity=27.3684210526316, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87082160, Length=183, Percent_Identity=25.6830601092896, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786701, Length=261, Percent_Identity=26.0536398467433, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=194, Percent_Identity=34.5360824742268, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=195, Percent_Identity=30.7692307692308, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=212, Percent_Identity=28.3018867924528, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17508895, Length=239, Percent_Identity=26.7782426778243, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562906, Length=207, Percent_Identity=30.4347826086957, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=202, Percent_Identity=29.2079207920792, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=205, Percent_Identity=30.7317073170732, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI25152911, Length=189, Percent_Identity=28.042328042328, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=204, Percent_Identity=30.8823529411765, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=253, Percent_Identity=26.0869565217391, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=246, Percent_Identity=26.8292682926829, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=209, Percent_Identity=24.8803827751196, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI212646214, Length=205, Percent_Identity=27.3170731707317, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=202, Percent_Identity=31.1881188118812, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=252, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=224, Percent_Identity=27.6785714285714, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17559552, Length=226, Percent_Identity=24.7787610619469, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=190, Percent_Identity=27.8947368421053, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=189, Percent_Identity=22.7513227513227, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=202, Percent_Identity=28.7128712871287, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=251, Percent_Identity=25.0996015936255, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=200, Percent_Identity=29, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=198, Percent_Identity=29.2929292929293, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319635, Length=178, Percent_Identity=25.8426966292135, Blast_Score=65, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24640442, Length=252, Percent_Identity=30.5555555555556, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24584744, Length=249, Percent_Identity=28.9156626506024, Blast_Score=97, Evalue=8e-21,
Organism=Drosophila melanogaster, GI28574402, Length=249, Percent_Identity=28.9156626506024, Blast_Score=97, Evalue=8e-21,
Organism=Drosophila melanogaster, GI161076933, Length=187, Percent_Identity=31.0160427807487, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24584748, Length=187, Percent_Identity=31.0160427807487, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24584752, Length=182, Percent_Identity=30.7692307692308, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI21357041, Length=178, Percent_Identity=33.7078651685393, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI28571526, Length=178, Percent_Identity=32.0224719101124, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24644339, Length=190, Percent_Identity=30.5263157894737, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI116007236, Length=208, Percent_Identity=27.8846153846154, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24580925, Length=206, Percent_Identity=29.126213592233, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI23397609, Length=178, Percent_Identity=30.3370786516854, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24649181, Length=187, Percent_Identity=26.2032085561497, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24648944, Length=209, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21358495, Length=246, Percent_Identity=23.9837398373984, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355319, Length=188, Percent_Identity=26.063829787234, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28185; Mature: 28185

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDMEATRDERPWALVSGASGGLGQAFSRHLASCGVNLVVTGRRHDVLDDLADQLTTRYG
CCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHH
IQTIVHPCDISSASERLALVNEIAGRGIIIDTLVNNAGFGAAGRIAETDPERQTSQVEVN
HHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEHHCCCCCCCCCCCCCCCCCCCCCEEEEH
CEAVVHLCGLLLPGMITAKRGSIINVASTAAFQPIPQFATYAASKSFVLSFTRALWAETN
HHHHHHHHHHHHCCHHEECCCCEEEEHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHCCC
GTGVRATAICPGPTETGFFDVAGVPRMAAGARRDPDDVVRTAFDALARHRPYAVDGFVNR
CCCEEEEEECCCCCCCCCEECCCCCHHHCCCCCCHHHHHHHHHHHHHHCCCCEEHHHHHH
TVARLAPHLPARLVMTQAEKYLQV
HHHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNDMEATRDERPWALVSGASGGLGQAFSRHLASCGVNLVVTGRRHDVLDDLADQLTTRYG
CCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHH
IQTIVHPCDISSASERLALVNEIAGRGIIIDTLVNNAGFGAAGRIAETDPERQTSQVEVN
HHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEHHCCCCCCCCCCCCCCCCCCCCCEEEEH
CEAVVHLCGLLLPGMITAKRGSIINVASTAAFQPIPQFATYAASKSFVLSFTRALWAETN
HHHHHHHHHHHHCCHHEECCCCEEEEHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHCCC
GTGVRATAICPGPTETGFFDVAGVPRMAAGARRDPDDVVRTAFDALARHRPYAVDGFVNR
CCCEEEEEECCCCCCCCCEECCCCCHHHCCCCCCHHHHHHHHHHHHHHCCCCEEHHHHHH
TVARLAPHLPARLVMTQAEKYLQV
HHHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]