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The map label for this gene is asd [H]

Identifier: 50841805

GI number: 50841805

Start: 369582

End: 370895

Strand: Direct

Name: asd [H]

Synonym: PPA0318

Alternate gene names: 50841805

Gene position: 369582-370895 (Clockwise)

Preceding gene: 50841804

Following gene: 50841806

Centisome position: 14.44

GC content: 60.96

Gene sequence:

>1314_bases
ATGGTCGACGACGATGGTTATCGTCACCTCGGCCATCATCCGCGGCACCTACCACCTCTACCAGGGCTGGGGCGACTTCA
TCGGCAACATCGTCATGGGCCTATTCCTGGGCTGGGTTTTCTCTCGTCGCTGTCGGCTCTTACCCCTCATCGTGGCGCAC
GCCTTCCTCGACATTGTCTCCTTCCTGGGATACGCCTATCTGGCTGGTCGCGTCAGCTGGTTATAAGGCAATTCGGACAC
TCACCGAACCTGTCGTCCCCTGCCCGTACCATGGGGATCATGAAGCTTGGAGTCTTCGGAGCCACTGGACAGGTTGGCCG
GGTGATGCGCACCCTGCTAGCCGAGCGTCATTTTCCCGCCGATGAAGTGCGGTTCTTCGCTTCCGCCCGTTCGGCTGGTC
AGAAGTTGTCGTGGAATAACGGTTCGGGTGACAGCGAAGTCGTCGTTGAGGACACCGCGACGGCTGACTTTGCTGGACTT
GATATTGCGATCTTTTCTGCGGGTGGCGGAACCTCCCGCGAGTTTGCCCCTCGCGTGGCGGCTGCCGGGGCTGTCGTTAT
CGACAACTCCTCCGCCTGGCGACGCGATCCTGACGTCCCGCTGGTTGTCAGCGAGGTCAATCCCGAAGATGTCGCTAAGC
GTCCCAAAGGGATCATTGCTAACCCCAACTGCACGACGATGGCCGCAATGCCGGTGCTCAAACCGCTACATGACGCTGCC
GGTCTGACTCGCCTTGTCGTCGCTACGTACCAGGCTGTTTCGGGGTCTGGGGTGGCCGGAGTACGAGCCCTCACCGACCA
AACCACGGCTATTGACGATCCGGCAGGCCTGGCGCTGGACGGCCGTGGTGTGCCGGTGGCGGACCTTGGGCCTTACGTCG
CACCGATCGCGTTCAACGCTCTTCCGGTGGCGGGAAACTTTGTTGACGATGGCAGCGGCGAGACTGACGAGGAACAGAAA
CTTCGCAATGAGTCTCGCAAGATCCTTCATATTCCTGATTTGCTGGTTGCGGGGACCTGCGTGCGGATTCCGGTGTATAG
CGGTCATGGGCTTGTCGTCCATGCTGAGTTCCGTGAGAGCCTCAGCCCTGAGAAGGCCACTGAGCTATTGACGCAGGCAC
CTGGAGTCAGGGTCGTCGACGTCCCGGATCCCCGGTCGGCAGCCGGAATTGACCCCTCGTTGGTTGGTCGTATTCGTGCT
GACCAGTCCGCACCGGCTGGCAAAGGTCTGGTGTTCTTCTGCGCTGCGGACAATTTGCGCAAGGGCGCGGCCCTCAACGC
GGTGCAGCTCGCTGAGCTGGTGGCTGCCGAATGA

Upstream 100 bases:

>100_bases
GGTGGACGGCCCCGGTTCTCATCGGGCTGGCAGGGATGAACGCAGTCCTTGAGGAAACTGTCATGATCGGCTACCTCTTT
ACGAGGTGGGGTCAGATCGG

Downstream 100 bases:

>100_bases
GCGGGAAGATTGCCGTCCTGGGCTGTGGAACGATGGCTGGGGCGCTTGTTGGTGGACTCATTGACGCTGGACAAATGAAG
GCCGAGGACGTCGTGGCAAC

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MVDDDGYRHLGHHPRHLPPLPGLGRLHRQHRHGPIPGLGFLSSLSALTPHRGARLPRHCLLPGIRLSGWSRQLVIRQFGH
SPNLSSPARTMGIMKLGVFGATGQVGRVMRTLLAERHFPADEVRFFASARSAGQKLSWNNGSGDSEVVVEDTATADFAGL
DIAIFSAGGGTSREFAPRVAAAGAVVIDNSSAWRRDPDVPLVVSEVNPEDVAKRPKGIIANPNCTTMAAMPVLKPLHDAA
GLTRLVVATYQAVSGSGVAGVRALTDQTTAIDDPAGLALDGRGVPVADLGPYVAPIAFNALPVAGNFVDDGSGETDEEQK
LRNESRKILHIPDLLVAGTCVRIPVYSGHGLVVHAEFRESLSPEKATELLTQAPGVRVVDVPDPRSAAGIDPSLVGRIRA
DQSAPAGKGLVFFCAADNLRKGAALNAVQLAELVAAE

Sequences:

>Translated_437_residues
MVDDDGYRHLGHHPRHLPPLPGLGRLHRQHRHGPIPGLGFLSSLSALTPHRGARLPRHCLLPGIRLSGWSRQLVIRQFGH
SPNLSSPARTMGIMKLGVFGATGQVGRVMRTLLAERHFPADEVRFFASARSAGQKLSWNNGSGDSEVVVEDTATADFAGL
DIAIFSAGGGTSREFAPRVAAAGAVVIDNSSAWRRDPDVPLVVSEVNPEDVAKRPKGIIANPNCTTMAAMPVLKPLHDAA
GLTRLVVATYQAVSGSGVAGVRALTDQTTAIDDPAGLALDGRGVPVADLGPYVAPIAFNALPVAGNFVDDGSGETDEEQK
LRNESRKILHIPDLLVAGTCVRIPVYSGHGLVVHAEFRESLSPEKATELLTQAPGVRVVDVPDPRSAAGIDPSLVGRIRA
DQSAPAGKGLVFFCAADNLRKGAALNAVQLAELVAAE
>Mature_437_residues
MVDDDGYRHLGHHPRHLPPLPGLGRLHRQHRHGPIPGLGFLSSLSALTPHRGARLPRHCLLPGIRLSGWSRQLVIRQFGH
SPNLSSPARTMGIMKLGVFGATGQVGRVMRTLLAERHFPADEVRFFASARSAGQKLSWNNGSGDSEVVVEDTATADFAGL
DIAIFSAGGGTSREFAPRVAAAGAVVIDNSSAWRRDPDVPLVVSEVNPEDVAKRPKGIIANPNCTTMAAMPVLKPLHDAA
GLTRLVVATYQAVSGSGVAGVRALTDQTTAIDDPAGLALDGRGVPVADLGPYVAPIAFNALPVAGNFVDDGSGETDEEQK
LRNESRKILHIPDLLVAGTCVRIPVYSGHGLVVHAEFRESLSPEKATELLTQAPGVRVVDVPDPRSAAGIDPSLVGRIRA
DQSAPAGKGLVFFCAADNLRKGAALNAVQLAELVAAE

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=348, Percent_Identity=32.7586206896552, Blast_Score=161, Evalue=7e-41,
Organism=Escherichia coli, GI1789841, Length=368, Percent_Identity=26.0869565217391, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320362, Length=310, Percent_Identity=29.3548387096774, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 46014; Mature: 46014

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDDDGYRHLGHHPRHLPPLPGLGRLHRQHRHGPIPGLGFLSSLSALTPHRGARLPRHCL
CCCCCCCHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHHHC
LPGIRLSGWSRQLVIRQFGHSPNLSSPARTMGIMKLGVFGATGQVGRVMRTLLAERHFPA
CCCCEECCCCHHHHHHHCCCCCCCCCHHHHHHHHEEEEECCCCHHHHHHHHHHHHCCCCH
DEVRFFASARSAGQKLSWNNGSGDSEVVVEDTATADFAGLDIAIFSAGGGTSREFAPRVA
HHHHHHHHHHHCCCEECCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCHHHCCHHH
AAGAVVIDNSSAWRRDPDVPLVVSEVNPEDVAKRPKGIIANPNCTTMAAMPVLKPLHDAA
HCCEEEEECCCCCCCCCCCCEEEECCCHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHH
GLTRLVVATYQAVSGSGVAGVRALTDQTTAIDDPAGLALDGRGVPVADLGPYVAPIAFNA
HHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCEEECCCCCCHHHCCCHHHHHHHCC
LPVAGNFVDDGSGETDEEQKLRNESRKILHIPDLLVAGTCVRIPVYSGHGLVVHAEFRES
EECCCCCCCCCCCCCCHHHHHHHHCCEEEECCCHHHCCCEEEEEEECCCCEEEEHHHHHC
LSPEKATELLTQAPGVRVVDVPDPRSAAGIDPSLVGRIRADQSAPAGKGLVFFCAADNLR
CCHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHEECCCCCCCCCCEEEEEECCCCC
KGAALNAVQLAELVAAE
CCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MVDDDGYRHLGHHPRHLPPLPGLGRLHRQHRHGPIPGLGFLSSLSALTPHRGARLPRHCL
CCCCCCCHHHCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHHHC
LPGIRLSGWSRQLVIRQFGHSPNLSSPARTMGIMKLGVFGATGQVGRVMRTLLAERHFPA
CCCCEECCCCHHHHHHHCCCCCCCCCHHHHHHHHEEEEECCCCHHHHHHHHHHHHCCCCH
DEVRFFASARSAGQKLSWNNGSGDSEVVVEDTATADFAGLDIAIFSAGGGTSREFAPRVA
HHHHHHHHHHHCCCEECCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCHHHCCHHH
AAGAVVIDNSSAWRRDPDVPLVVSEVNPEDVAKRPKGIIANPNCTTMAAMPVLKPLHDAA
HCCEEEEECCCCCCCCCCCCEEEECCCHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHH
GLTRLVVATYQAVSGSGVAGVRALTDQTTAIDDPAGLALDGRGVPVADLGPYVAPIAFNA
HHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCEEECCCCCCHHHCCCHHHHHHHCC
LPVAGNFVDDGSGETDEEQKLRNESRKILHIPDLLVAGTCVRIPVYSGHGLVVHAEFRES
EECCCCCCCCCCCCCCHHHHHHHHCCEEEECCCHHHCCCEEEEEEECCCCEEEEHHHHHC
LSPEKATELLTQAPGVRVVDVPDPRSAAGIDPSLVGRIRADQSAPAGKGLVFFCAADNLR
CCHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHEECCCCCCCCCCEEEEEECCCCC
KGAALNAVQLAELVAAE
CCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7910936; 12788972 [H]