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The map label for this gene is ftsW [H]

Identifier: 50841675

GI number: 50841675

Start: 227224

End: 228615

Strand: Reverse

Name: ftsW [H]

Synonym: PPA0186

Alternate gene names: 50841675

Gene position: 228615-227224 (Counterclockwise)

Preceding gene: 50841676

Following gene: 50841674

Centisome position: 8.93

GC content: 59.34

Gene sequence:

>1392_bases
ATGAGTATCGGACAGGAATTTGATGACGGCACCGTCGTCATCCAGGCCAAGAGGCGCTGGACGGAACTCTTCATGCTCCT
CATCGCCTGGGCTATCGGCTTCGGCGGATGGGTTCTCACCGAGCTCAACATCAACCACGTGCTGCCAGATACGTGGACAA
CCGTCGGCGGCGTGTGGCTGGCGGTGGCTATCGTCGCGCATATTTTCGTGAGGATCGTCATTCCCTACGCTGACCCGGTA
ATCCTGCCTATCGTCTTCACTCTCAATGGGCTCGGGCTAGCGATGATCCATCGCATCGACTACATTCCTGATCCGCACTA
TCACCGCATGGATGCCCAGGCTTTGTGGACGGCTTTGGGTATTGTCCTCTTCGTCGCGACGCTGCTCATCCTGCGCGACC
ACCGCAACTTGCAGCGCTACCCGTATGTACTGTTCATTGTGGGCCTGGTTTTCCTCATGCTGCCCTTGGTGCCGGGCCTG
GGCATGGCGACGTTGGGGTCGCGGGTGTGGATCCACGTTGGCTCCTACACCTTCCAGCCAGCCGAAGTATCAAAGGTCGT
GCTCGCTATCGCTTTTGCTGGCTACCTCGTCGACAATCGTGACGTCCTTTCCCGCGCCGGGCACAAGATCCTTGGAATCA
CTCTGCCGCGCGCGCGCGACCTCGGGCCAATTGCCGTTATGTGGGTAGCAACGATGCTCGTCATCGTCTACCAGAACGAC
CTGGGCACCGGAATGCTGTTCTACGGCATGTTCGTCGTGATGCTGTACATCACCACCGAACGAGTCGGATGGGCCATACT
AGGGGCGGTGAGCTTCCTCGGCGGCGCTGTGCTGGCGTATACCTGCTTCGGCCACGTACGAGTTCGCTTCGACTCATGGC
TGCACCCATTCAGCAACTACACCCAGAACTACCAAATCATCCAGGCACAATTCGGGCTCGCCTGGGGAGGATTAGCCGGA
CGCGGCTGGGGGTTAGGACGCCCCGGCATGGTTCCGCTAGCGTGGAGTGACTTCATCGCTACATCCATAGGTGAGGAACT
CGGCGTCACCGGCCTCATGGCCGTCATCGTGCTCTTCTTCATCCTTACCGCCCGCGGAATGCGCACCAGCCTCGGTTGCC
GTGATGACTTCGGCAAGCTTATGGTCGCTGGCTTGTCCTTCACCCTCGCCCTGCAGGTCTTCGCCATCATCGGTGGCGTC
ACCCGCCTTCTACCATTGACCGGTCTGACAACGCCATTTATGAGTCAAGGTGGTTCTTCGTTGATCGCAAACTGGGTCAT
CGTTGCGATCATCATGATCGTCTCACACCGGAACCGAAAGCCTGCCGACGACTTCGCCGCCACCGTCCCGGCACCTGATC
CGCAACAGGCCATCACCGGAGGCACGCGATGA

Upstream 100 bases:

>100_bases
TACCAACCCCGGCCATGCCGACGCCAACTTCCGCTATGCCCTCACCGAGCGCCGCAGGCCATGAAGTCGACCTCCCGGCC
GTCACTTCGGGGGATTGCCA

Downstream 100 bases:

>100_bases
ATAGACAAATTCGCGCAGTCTCTTTGCTCGCCGGGCTGATGTTCCTGGCCCTCATGGTCAACCTCACAGGTTCGGCTATG
TTCCGGCAGGCCAGTCTCAA

Product: putative cell division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MSIGQEFDDGTVVIQAKRRWTELFMLLIAWAIGFGGWVLTELNINHVLPDTWTTVGGVWLAVAIVAHIFVRIVIPYADPV
ILPIVFTLNGLGLAMIHRIDYIPDPHYHRMDAQALWTALGIVLFVATLLILRDHRNLQRYPYVLFIVGLVFLMLPLVPGL
GMATLGSRVWIHVGSYTFQPAEVSKVVLAIAFAGYLVDNRDVLSRAGHKILGITLPRARDLGPIAVMWVATMLVIVYQND
LGTGMLFYGMFVVMLYITTERVGWAILGAVSFLGGAVLAYTCFGHVRVRFDSWLHPFSNYTQNYQIIQAQFGLAWGGLAG
RGWGLGRPGMVPLAWSDFIATSIGEELGVTGLMAVIVLFFILTARGMRTSLGCRDDFGKLMVAGLSFTLALQVFAIIGGV
TRLLPLTGLTTPFMSQGGSSLIANWVIVAIIMIVSHRNRKPADDFAATVPAPDPQQAITGGTR

Sequences:

>Translated_463_residues
MSIGQEFDDGTVVIQAKRRWTELFMLLIAWAIGFGGWVLTELNINHVLPDTWTTVGGVWLAVAIVAHIFVRIVIPYADPV
ILPIVFTLNGLGLAMIHRIDYIPDPHYHRMDAQALWTALGIVLFVATLLILRDHRNLQRYPYVLFIVGLVFLMLPLVPGL
GMATLGSRVWIHVGSYTFQPAEVSKVVLAIAFAGYLVDNRDVLSRAGHKILGITLPRARDLGPIAVMWVATMLVIVYQND
LGTGMLFYGMFVVMLYITTERVGWAILGAVSFLGGAVLAYTCFGHVRVRFDSWLHPFSNYTQNYQIIQAQFGLAWGGLAG
RGWGLGRPGMVPLAWSDFIATSIGEELGVTGLMAVIVLFFILTARGMRTSLGCRDDFGKLMVAGLSFTLALQVFAIIGGV
TRLLPLTGLTTPFMSQGGSSLIANWVIVAIIMIVSHRNRKPADDFAATVPAPDPQQAITGGTR
>Mature_462_residues
SIGQEFDDGTVVIQAKRRWTELFMLLIAWAIGFGGWVLTELNINHVLPDTWTTVGGVWLAVAIVAHIFVRIVIPYADPVI
LPIVFTLNGLGLAMIHRIDYIPDPHYHRMDAQALWTALGIVLFVATLLILRDHRNLQRYPYVLFIVGLVFLMLPLVPGLG
MATLGSRVWIHVGSYTFQPAEVSKVVLAIAFAGYLVDNRDVLSRAGHKILGITLPRARDLGPIAVMWVATMLVIVYQNDL
GTGMLFYGMFVVMLYITTERVGWAILGAVSFLGGAVLAYTCFGHVRVRFDSWLHPFSNYTQNYQIIQAQFGLAWGGLAGR
GWGLGRPGMVPLAWSDFIATSIGEELGVTGLMAVIVLFFILTARGMRTSLGCRDDFGKLMVAGLSFTLALQVFAIIGGVT
RLLPLTGLTTPFMSQGGSSLIANWVIVAIIMIVSHRNRKPADDFAATVPAPDPQQAITGGTR

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=342, Percent_Identity=29.5321637426901, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1786277, Length=330, Percent_Identity=26.3636363636364, Blast_Score=96, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 50712; Mature: 50581

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIGQEFDDGTVVIQAKRRWTELFMLLIAWAIGFGGWVLTELNINHVLPDTWTTVGGVWL
CCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHH
AVAIVAHIFVRIVIPYADPVILPIVFTLNGLGLAMIHRIDYIPDPHYHRMDAQALWTALG
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
IVLFVATLLILRDHRNLQRYPYVLFIVGLVFLMLPLVPGLGMATLGSRVWIHVGSYTFQP
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCEEEEEECCEECCH
AEVSKVVLAIAFAGYLVDNRDVLSRAGHKILGITLPRARDLGPIAVMWVATMLVIVYQND
HHHHHHHHHHHHHHHHCCCHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCC
LGTGMLFYGMFVVMLYITTERVGWAILGAVSFLGGAVLAYTCFGHVRVRFDSWLHPFSNY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHCCHHHHC
TQNYQIIQAQFGLAWGGLAGRGWGLGRPGMVPLAWSDFIATSIGEELGVTGLMAVIVLFF
CCCCEEEEEECCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHH
ILTARGMRTSLGCRDDFGKLMVAGLSFTLALQVFAIIGGVTRLLPLTGLTTPFMSQGGSS
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHH
LIANWVIVAIIMIVSHRNRKPADDFAATVPAPDPQQAITGGTR
HHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCHHHCCCCCC
>Mature Secondary Structure 
SIGQEFDDGTVVIQAKRRWTELFMLLIAWAIGFGGWVLTELNINHVLPDTWTTVGGVWL
CCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHH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HHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]