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The map label for this gene is yuxJ

Identifier: 50812285

GI number: 50812285

Start: 3232640

End: 3233818

Strand: Direct

Name: yuxJ

Synonym: BSU31480

Alternate gene names: 50812285

Gene position: 3232640-3233818 (Clockwise)

Preceding gene: 16080198

Following gene: 255767716

Centisome position: 76.68

GC content: 49.36

Gene sequence:

>1179_bases
GTGTGGCTGGCGAACTTTTTTGTCTCCGCTAGCACAACGATGATCGTTCCTTTTCTCTCCTTATACATTGAGACGCTCAG
CTCTTTTTCAAACGGCTTTGTGCAAAGGTGGAGCGGCTATGTGTTCGGCATTACATTTCTCATGGCGTTTTTGGTATCCC
CGTTTTGGGGACGGTTCGGAGACAAACGCGGATACAAGAAAATCCTTATGGCAACCGGAACAGGCATTGCCCTCAGCATT
TTCTTCATGGGCTTTGTTACATCGGTGTACCAATTGTTTTTTCTGCGTATGGCAATGGGTCTTGTAACCGGATTCATCCC
GACATCTCTTGCGATGATTTCGGCACAGACTCCGAAGAGCTCAGCTGGCAAAACACTCGGCACGCTGCAAATGGGGCAAG
TGTCCGGAAGCTTGTTCGGCCCGCTTTTGGGAGGCATGCTTGCTGATCGTTTCGGCTTTACGTATACCTTTTTTATCACA
TCCTTTGTGATTTTCTCGTCTGTTCTTCTCGTGTTATTTGGTGTCAAAGAAAAGCATCTTGCAGAGAAAACAGCCAAACG
TACGTCTTACTCGAGAAAAGAAGTGCTCTCCTATATTTTTCACCATCCGGCGCTGTGGGTCATGATGCTGTTAACCATGC
TGATTCAAACAGGCAATTTCAGTATCCAGCCCCTGCTCGCTTTATATGTAAATGAGCTGCACGGACCTGTCAATCTTGCC
TTTTTCTCCGGCATGGCATTTTCAGCAACGGGGCTCGGAAGTTTGCTGCTGGCTAGAAAATGGGGTGATCTGGGCGACCG
CTACGGCCACCGCCGCATTTTAATCGGACTTTTGCTCGCCGCCTCTTTCTTTTTTATTCCGCAGGCGCTCGCGTCCTCAC
TCAGCGTGCTCCTTGTTTTCAGATTTTTATTCGGAATGGCGATGGGCGGTTTGCTGCCATGCATTACGGCAGCGATCCGC
GTTCAGGCTCCCGGCAGCATTCAAGGTGAAGTTCTCGGCTACAATGTCAGCTTTCGCTTTTTAGGAAACGTGCTCGGGCC
TCTGCTCGGCGGAATCATATCGAGCCATTTTACCATTTCGGCCACCTTTTACGTCACGGCGTTTCTCTTTTTCGCCGGCG
CCTGCATGCTTTGGATCATGCAGAAACTTCGGAAAGATTCTTATGCCAAAGCAAGCTGA

Upstream 100 bases:

>100_bases
CGTTTCTTTTAAATTGTGAATCGTTTCTTTATAATTAGTAAGGAACCCGAAATAATAAGAAGGTGATGTTATTTCTATCC
GTAAGAAAAACTTTGTCATT

Downstream 100 bases:

>100_bases
TTCCGAGAAAAAACTAAGGAATCTTCTAAATTTAACCTTCTCGTAATCTCAAAAGAATGGTACGATATGGCTAGAATTTA
GGAGAAAAGAGAGTGACCAT

Product: exporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: ORF1

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MWLANFFVSASTTMIVPFLSLYIETLSSFSNGFVQRWSGYVFGITFLMAFLVSPFWGRFGDKRGYKKILMATGTGIALSI
FFMGFVTSVYQLFFLRMAMGLVTGFIPTSLAMISAQTPKSSAGKTLGTLQMGQVSGSLFGPLLGGMLADRFGFTYTFFIT
SFVIFSSVLLVLFGVKEKHLAEKTAKRTSYSRKEVLSYIFHHPALWVMMLLTMLIQTGNFSIQPLLALYVNELHGPVNLA
FFSGMAFSATGLGSLLLARKWGDLGDRYGHRRILIGLLLAASFFFIPQALASSLSVLLVFRFLFGMAMGGLLPCITAAIR
VQAPGSIQGEVLGYNVSFRFLGNVLGPLLGGIISSHFTISATFYVTAFLFFAGACMLWIMQKLRKDSYAKAS

Sequences:

>Translated_392_residues
MWLANFFVSASTTMIVPFLSLYIETLSSFSNGFVQRWSGYVFGITFLMAFLVSPFWGRFGDKRGYKKILMATGTGIALSI
FFMGFVTSVYQLFFLRMAMGLVTGFIPTSLAMISAQTPKSSAGKTLGTLQMGQVSGSLFGPLLGGMLADRFGFTYTFFIT
SFVIFSSVLLVLFGVKEKHLAEKTAKRTSYSRKEVLSYIFHHPALWVMMLLTMLIQTGNFSIQPLLALYVNELHGPVNLA
FFSGMAFSATGLGSLLLARKWGDLGDRYGHRRILIGLLLAASFFFIPQALASSLSVLLVFRFLFGMAMGGLLPCITAAIR
VQAPGSIQGEVLGYNVSFRFLGNVLGPLLGGIISSHFTISATFYVTAFLFFAGACMLWIMQKLRKDSYAKAS
>Mature_392_residues
MWLANFFVSASTTMIVPFLSLYIETLSSFSNGFVQRWSGYVFGITFLMAFLVSPFWGRFGDKRGYKKILMATGTGIALSI
FFMGFVTSVYQLFFLRMAMGLVTGFIPTSLAMISAQTPKSSAGKTLGTLQMGQVSGSLFGPLLGGMLADRFGFTYTFFIT
SFVIFSSVLLVLFGVKEKHLAEKTAKRTSYSRKEVLSYIFHHPALWVMMLLTMLIQTGNFSIQPLLALYVNELHGPVNLA
FFSGMAFSATGLGSLLLARKWGDLGDRYGHRRILIGLLLAASFFFIPQALASSLSVLLVFRFLFGMAMGGLLPCITAAIR
VQAPGSIQGEVLGYNVSFRFLGNVLGPLLGGIISSHFTISATFYVTAFLFFAGACMLWIMQKLRKDSYAKAS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily

Homologues:

Organism=Escherichia coli, GI1787291, Length=392, Percent_Identity=37.5, Blast_Score=251, Evalue=6e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YUXJ_BACSU (P40760)

Other databases:

- EMBL:   Z93933
- EMBL:   AL009126
- EMBL:   U11882
- PIR:   C70025
- RefSeq:   NP_391026.2
- ProteinModelPortal:   P40760
- SMR:   P40760
- EnsemblBacteria:   EBBACT00000003319
- GeneID:   938852
- GenomeReviews:   AL009126_GR
- KEGG:   bsu:BSU31480
- GenoList:   BSU31480
- GeneTree:   EBGT00070000031981
- HOGENOM:   HBG404070
- OMA:   NVSFRFL
- PhylomeDB:   P40760
- ProtClustDB:   CLSK895050
- BioCyc:   BSUB:BSU31480-MONOMER
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001958
- PRINTS:   PR01035

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 43051; Mature: 43051

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x11613eb4)-; HASH(0x120bcfc0)-; HASH(0x11fd20a0)-; HASH(0xff6eb68)-; HASH(0x11f61368)-; HASH(0xf9eed90)-; HASH(0x12151f38)-; HASH(0x1174e6f4)-; HASH(0x120dad8c)-; HASH(0x11e75e20)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377; 10568751; 7961491