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The map label for this gene is treR [H]

Identifier: 50365318

GI number: 50365318

Start: 588125

End: 589072

Strand: Reverse

Name: treR [H]

Synonym: Mfl501

Alternate gene names: 50365318

Gene position: 589072-588125 (Counterclockwise)

Preceding gene: 50365319

Following gene: 50365317

Centisome position: 74.26

GC content: 23.1

Gene sequence:

>948_bases
ATGAAAAAAACAAAAATGACTTATCATGATATTGCTAAAAAAGCTGGTGTTGGAATAGGAACTGTTTCTAGATATTTTAA
TGATTACAATATTTCTGAAGAAGCTAAATCAAAAATCAATAAAGTTTTAAACGAAACTGACTATGTCCCTAATTTTGCAG
CATCTAATATTAAAAAGCCTAGTAAAGATGTTTATTTAATATTGCCTTACAATAACGATGAGACAGCTAATATGGAAATT
GTTAATGGTGTCAAGAGTTCATTAACAGCTGATAATATTAATTTCTTTATTTTTCTTTCATCATCTGAAAGTGAAATTTA
TCAAAAAGATTTAAAATATTTAACAATGAGAAACCCGTTTGGAATTGTTTTATTATTACCCAAACATACTTCTAAAGATT
TAATACTACAAATTCAAGATATAAAATCAACTAACTTAATTGTTTATAACAGAAATATTGAAGGAGTTAAATCTGTTAAC
ATTGATGATAAAGAAATGTTTAAAGAACTAGCTTTAAAAATTGAAACTGACTATAAAAATGAAAAAGTTGCATTTATTGG
TCTAAACAAAGAAGACATTACAACAGGAAAATATAGATCTGAATCTTTTACAGAAAATATTAAAAACAATAAAGTTCAAA
ATTACTTATTAAAACAAAATTCTTTTGAAGATGTTGAAGAAATTATTCACAAAATAATAAAAGACTATAATCCTAAAATT
ATAGTAAGCGCAACACATACTATATCAATGTATGTGTATGGTCATTTAATGGAAAATAAAATAAGAAACAATTTTATTAC
AACTGATATTGGAAGAATGGGAAAAAGTCAATATTTAACTAATTCAGACATAAATATCTTTATTGATTACTTTTTAATAG
GATATCAAATTGGGAATAAATTATTAAATAAAGAAAAGAAAATGGAAAATTTCTTCAAAATTATTTAA

Upstream 100 bases:

>100_bases
ATCAAAAAATAATTTATAAAATTTAGAGTGCCATTAAGCACTCTTTTTGTTTGTTAAAAGTAATATAATTAATTTATAGA
AAACAAATAAAAGGGATTAT

Downstream 100 bases:

>100_bases
TAGTTTATTTTTTTATATATAATAATAGTGTTGGAAATGTTTCCAATAGAAAGGCAAAGATTATGGGTAAAAAAGAAAAA
TTACCACAAGTAAAGATTGA

Product: trehalose operon repressor, repressor of treA,B,C

Products: NA

Alternate protein names: Trehalose operon repressor [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MKKTKMTYHDIAKKAGVGIGTVSRYFNDYNISEEAKSKINKVLNETDYVPNFAASNIKKPSKDVYLILPYNNDETANMEI
VNGVKSSLTADNINFFIFLSSSESEIYQKDLKYLTMRNPFGIVLLLPKHTSKDLILQIQDIKSTNLIVYNRNIEGVKSVN
IDDKEMFKELALKIETDYKNEKVAFIGLNKEDITTGKYRSESFTENIKNNKVQNYLLKQNSFEDVEEIIHKIIKDYNPKI
IVSATHTISMYVYGHLMENKIRNNFITTDIGRMGKSQYLTNSDINIFIDYFLIGYQIGNKLLNKEKKMENFFKII

Sequences:

>Translated_315_residues
MKKTKMTYHDIAKKAGVGIGTVSRYFNDYNISEEAKSKINKVLNETDYVPNFAASNIKKPSKDVYLILPYNNDETANMEI
VNGVKSSLTADNINFFIFLSSSESEIYQKDLKYLTMRNPFGIVLLLPKHTSKDLILQIQDIKSTNLIVYNRNIEGVKSVN
IDDKEMFKELALKIETDYKNEKVAFIGLNKEDITTGKYRSESFTENIKNNKVQNYLLKQNSFEDVEEIIHKIIKDYNPKI
IVSATHTISMYVYGHLMENKIRNNFITTDIGRMGKSQYLTNSDINIFIDYFLIGYQIGNKLLNKEKKMENFFKII
>Mature_315_residues
MKKTKMTYHDIAKKAGVGIGTVSRYFNDYNISEEAKSKINKVLNETDYVPNFAASNIKKPSKDVYLILPYNNDETANMEI
VNGVKSSLTADNINFFIFLSSSESEIYQKDLKYLTMRNPFGIVLLLPKHTSKDLILQIQDIKSTNLIVYNRNIEGVKSVN
IDDKEMFKELALKIETDYKNEKVAFIGLNKEDITTGKYRSESFTENIKNNKVQNYLLKQNSFEDVEEIIHKIIKDYNPKI
IVSATHTISMYVYGHLMENKIRNNFITTDIGRMGKSQYLTNSDINIFIDYFLIGYQIGNKLLNKEKKMENFFKII

Specific function: Repressor of the treBC operon. Binds trehalose 6- phosphate as an inducer [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790689, Length=308, Percent_Identity=22.0779220779221, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761
- InterPro:   IPR012771 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36455; Mature: 36455

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTKMTYHDIAKKAGVGIGTVSRYFNDYNISEEAKSKINKVLNETDYVPNFAASNIKKP
CCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHHCCCCC
SKDVYLILPYNNDETANMEIVNGVKSSLTADNINFFIFLSSSESEIYQKDLKYLTMRNPF
CCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHEEECCCC
GIVLLLPKHTSKDLILQIQDIKSTNLIVYNRNIEGVKSVNIDDKEMFKELALKIETDYKN
EEEEEECCCCCCCEEEEEEECCCCEEEEEECCCCCCEECCCCHHHHHHHHHEEEECCCCC
EKVAFIGLNKEDITTGKYRSESFTENIKNNKVQNYLLKQNSFEDVEEIIHKIIKDYNPKI
CEEEEEECCHHHCCCCCCCCHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCEE
IVSATHTISMYVYGHLMENKIRNNFITTDIGRMGKSQYLTNSDINIFIDYFLIGYQIGNK
EEEECCEEEEEHHHHHHHHHHHCCCEECCHHHCCCCCEECCCCCEEEEHHHHHHHHHHHH
LLNKEKKMENFFKII
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKTKMTYHDIAKKAGVGIGTVSRYFNDYNISEEAKSKINKVLNETDYVPNFAASNIKKP
CCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHHCCCCC
SKDVYLILPYNNDETANMEIVNGVKSSLTADNINFFIFLSSSESEIYQKDLKYLTMRNPF
CCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHEEECCCC
GIVLLLPKHTSKDLILQIQDIKSTNLIVYNRNIEGVKSVNIDDKEMFKELALKIETDYKN
EEEEEECCCCCCCEEEEEEECCCCEEEEEECCCCCCEECCCCHHHHHHHHHEEEECCCCC
EKVAFIGLNKEDITTGKYRSESFTENIKNNKVQNYLLKQNSFEDVEEIIHKIIKDYNPKI
CEEEEEECCHHHCCCCCCCCHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCEE
IVSATHTISMYVYGHLMENKIRNNFITTDIGRMGKSQYLTNSDINIFIDYFLIGYQIGNK
EEEECCEEEEEHHHHHHHHHHHCCCEECCHHHCCCCCEECCCCCEEEEHHHHHHHHHHHH
LLNKEKKMENFFKII
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9148912; 7610040; 9278503; 7608078; 9865945 [H]