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The map label for this gene is bglH [H]

Identifier: 50365248

GI number: 50365248

Start: 507621

End: 509063

Strand: Reverse

Name: bglH [H]

Synonym: Mfl430

Alternate gene names: 50365248

Gene position: 509063-507621 (Counterclockwise)

Preceding gene: 50365249

Following gene: 50365247

Centisome position: 64.18

GC content: 26.2

Gene sequence:

>1443_bases
ATGGAAAAATTAAGTAAAGATATAATGTTGGGAACTTCAATATCAGCTAATCAAGCAGAAGGTTCATGAAATATTAATGG
TAAAGGTTTATCAATAGCTGAAATGCGTAGATATAATCCATCTTTGGATCAAAAAGATATTAATACTGAAAGAAAAATGA
CTGAAGATAAAATAAAAGAAGCTTTAGACCCTAATTCAAAATTTTATTATCCTAAAAAAAATGGAATAGATTTTTTCAAA
CATTTTAAAGAAGATATTAAACTATTAGCTGAAATGAATAACGATTGTTTTAGAACATCAATTGCATGAACAAGGATTTT
TCCTAATGGAGATGAAACAGACCCAAATGAAGAGGGATTAAAATTTTATGATCAACTGATTGATGAATTAATAAAAAATA
ATATAGAGCCTATAATAACAATTTCTCATTATGAAATGCCTTATTATTTGGTTGAAAAATTTGGTGGATGAAAAAATAGA
GCATTAATAGATTTTTATACAAAGTATGCAAAAACTTTACTAATTAGATTTAAAGATAAAGTTAAATACTGAATTCCTTT
TAATGAAATGAATGCTGCAAATTATAGTGTTTGAGCTGGAGCTGGTTTAAGAGATGATGAACACGAAAATATTTTGGGTC
TATCAATTTATGCTTTACACAATATTTTTGTTGCTAATGCTTCAATTATTAAAGAAGGTAGAAAAATAAACTCAGAGTTT
AAGTTTGGATCAATGATTGCAACTTTATTATCTTATGCAGATGATTCAAACCCTTTAACTGTTTTGAAAGCTGATAAAGA
TCAACAAATGAAAATTTATGCTTATTTTGATGTACTACATCGTGGTGAATATCCTAAATATGCATTAAATCTTTATAAAT
CTTTTGGTATGAATTTAAAAATTAGTGAAGAAGATAGAATTGTGCTAAAAGAAAATACATGTGACTTTGTTGGATTTAGT
TATTACATGTCAGGTGTTGTTAGTTTAAATGAAGATTCATTAACTGAAGGAAATTTAGTTAAAGTTGGAAAAAATAAACA
CTTGAAAGAAAATGACTGGGGTTGACAAATTGACCCTGTAGGATTAAGAATATTAATGAATAGATTATATGATAGATATC
AAAAGCCTTTATTCATTTTAGAAAATGGTGTTGGATTTAAAGAAGAAAATCCAAATTTAGAAATGATTAATGATGATTAT
AGAATTGAATATTTAAAATCACATTTACAACAAGTTCAAAAAGCTGTTGATGATGGTGTTGAATGTATTGGTTATACAAT
GTGAAGTCCTTTTGATATTGTTTCTCATGGAACTAGTGAAATGGCAAAAAGATATGGTCTTATATATGTGGATCAAGATG
ATATGGGTAATGGAACTAAAAAAAGAATACCTAAAAAATCATATTACTGATTTAAAGAAGTTTGTGAAAAAAGAGAAATT
TAA

Upstream 100 bases:

>100_bases
AAATATTTTAAAGAAAGAACAAATAAAATACTTTTTGATGAATACGGATTTACTCCTGAATTAAAACAAAAAAGTATATT
TAAATTTAAAGGTAATAAAA

Downstream 100 bases:

>100_bases
AACCCTTACGGGTTTTTTGTTTTGTTACAAATATATATATTTGACTTTATTAATTTTAATTGTTAAAATATTTTAAATTA
AATTAAACATACTATAAGGG

Product: 6-phospho-beta-glucosidase

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MEKLSKDIMLGTSISANQAEGSWNINGKGLSIAEMRRYNPSLDQKDINTERKMTEDKIKEALDPNSKFYYPKKNGIDFFK
HFKEDIKLLAEMNNDCFRTSIAWTRIFPNGDETDPNEEGLKFYDQLIDELIKNNIEPIITISHYEMPYYLVEKFGGWKNR
ALIDFYTKYAKTLLIRFKDKVKYWIPFNEMNAANYSVWAGAGLRDDEHENILGLSIYALHNIFVANASIIKEGRKINSEF
KFGSMIATLLSYADDSNPLTVLKADKDQQMKIYAYFDVLHRGEYPKYALNLYKSFGMNLKISEEDRIVLKENTCDFVGFS
YYMSGVVSLNEDSLTEGNLVKVGKNKHLKENDWGWQIDPVGLRILMNRLYDRYQKPLFILENGVGFKEENPNLEMINDDY
RIEYLKSHLQQVQKAVDDGVECIGYTMWSPFDIVSHGTSEMAKRYGLIYVDQDDMGNGTKKRIPKKSYYWFKEVCEKREI

Sequences:

>Translated_480_residues
MEKLSKDIMLGTSISANQAEGS*NINGKGLSIAEMRRYNPSLDQKDINTERKMTEDKIKEALDPNSKFYYPKKNGIDFFK
HFKEDIKLLAEMNNDCFRTSIA*TRIFPNGDETDPNEEGLKFYDQLIDELIKNNIEPIITISHYEMPYYLVEKFGG*KNR
ALIDFYTKYAKTLLIRFKDKVKY*IPFNEMNAANYSV*AGAGLRDDEHENILGLSIYALHNIFVANASIIKEGRKINSEF
KFGSMIATLLSYADDSNPLTVLKADKDQQMKIYAYFDVLHRGEYPKYALNLYKSFGMNLKISEEDRIVLKENTCDFVGFS
YYMSGVVSLNEDSLTEGNLVKVGKNKHLKENDWG*QIDPVGLRILMNRLYDRYQKPLFILENGVGFKEENPNLEMINDDY
RIEYLKSHLQQVQKAVDDGVECIGYTM*SPFDIVSHGTSEMAKRYGLIYVDQDDMGNGTKKRIPKKSYY*FKEVCEKREI
>Mature_480_residues
MEKLSKDIMLGTSISANQAEGS*NINGKGLSIAEMRRYNPSLDQKDINTERKMTEDKIKEALDPNSKFYYPKKNGIDFFK
HFKEDIKLLAEMNNDCFRTSIA*TRIFPNGDETDPNEEGLKFYDQLIDELIKNNIEPIITISHYEMPYYLVEKFGG*KNR
ALIDFYTKYAKTLLIRFKDKVKY*IPFNEMNAANYSV*AGAGLRDDEHENILGLSIYALHNIFVANASIIKEGRKINSEF
KFGSMIATLLSYADDSNPLTVLKADKDQQMKIYAYFDVLHRGEYPKYALNLYKSFGMNLKISEEDRIVLKENTCDFVGFS
YYMSGVVSLNEDSLTEGNLVKVGKNKHLKENDWG*QIDPVGLRILMNRLYDRYQKPLFILENGVGFKEENPNLEMINDDY
RIEYLKSHLQQVQKAVDDGVECIGYTM*SPFDIVSHGTSEMAKRYGLIYVDQDDMGNGTKKRIPKKSYY*FKEVCEKREI

Specific function: Catalyzes the hydrolysis of aryl-phospho-beta-D- glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Plays a major role in the utilization of arbutin or salicin as the sole carbon source. Bgl

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI32481206, Length=478, Percent_Identity=28.4518828451883, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI110681710, Length=490, Percent_Identity=26.9387755102041, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI13273313, Length=407, Percent_Identity=24.0786240786241, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI28376633, Length=481, Percent_Identity=26.4033264033264, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI24497614, Length=480, Percent_Identity=24.5833333333333, Blast_Score=76, Evalue=6e-14,
Organism=Escherichia coli, GI2367174, Length=482, Percent_Identity=44.8132780082988, Blast_Score=369, Evalue=1e-103,
Organism=Escherichia coli, GI2367270, Length=481, Percent_Identity=40.7484407484407, Blast_Score=344, Evalue=7e-96,
Organism=Escherichia coli, GI1789070, Length=474, Percent_Identity=38.8185654008439, Blast_Score=325, Evalue=3e-90,
Organism=Caenorhabditis elegans, GI17552856, Length=490, Percent_Identity=27.7551020408163, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17539390, Length=476, Percent_Identity=27.5210084033613, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI21356577, Length=508, Percent_Identity=25.3937007874016, Blast_Score=112, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 54307; Mature: 54307

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLSKDIMLGTSISANQAEGSNINGKGLSIAEMRRYNPSLDQKDINTERKMTEDKIKEA
CCCHHCHHEECCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
LDPNSKFYYPKKNGIDFFKHFKEDIKLLAEMNNDCFRTSIATRIFPNGDETDPNEEGLKF
HCCCCCEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHEECCCCCCCCCCHHHHHH
YDQLIDELIKNNIEPIITISHYEMPYYLVEKFGGKNRALIDFYTKYAKTLLIRFKDKVKY
HHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCEEE
IPFNEMNAANYSVAGAGLRDDEHENILGLSIYALHNIFVANASIIKEGRKINSEFKFGSM
CCCCCCCCCCCEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCHHCCCCCHHHHH
IATLLSYADDSNPLTVLKADKDQQMKIYAYFDVLHRGEYPKYALNLYKSFGMNLKISEED
HHHHHHHCCCCCCEEEEECCCCCCEEEEEEEHHHHCCCCCHHHHHHHHHHCCCEEECCCC
RIVLKENTCDFVGFSYYMSGVVSLNEDSLTEGNLVKVGKNKHLKENDWGQIDPVGLRILM
CEEEECCCCCCEEHHHHHHCEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHH
NRLYDRYQKPLFILENGVGFKEENPNLEMINDDYRIEYLKSHLQQVQKAVDDGVECIGYT
HHHHHHHCCCEEEEECCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCHHEEECC
MSPFDIVSHGTSEMAKRYGLIYVDQDDMGNGTKKRIPKKSYYFKEVCEKREI
CCHHHHHHCCHHHHHHHCCEEEEECCCCCCCHHHCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MEKLSKDIMLGTSISANQAEGSNINGKGLSIAEMRRYNPSLDQKDINTERKMTEDKIKEA
CCCHHCHHEECCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
LDPNSKFYYPKKNGIDFFKHFKEDIKLLAEMNNDCFRTSIATRIFPNGDETDPNEEGLKF
HCCCCCEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHEECCCCCCCCCCHHHHHH
YDQLIDELIKNNIEPIITISHYEMPYYLVEKFGGKNRALIDFYTKYAKTLLIRFKDKVKY
HHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCEEE
IPFNEMNAANYSVAGAGLRDDEHENILGLSIYALHNIFVANASIIKEGRKINSEFKFGSM
CCCCCCCCCCCEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCHHCCCCCHHHHH
IATLLSYADDSNPLTVLKADKDQQMKIYAYFDVLHRGEYPKYALNLYKSFGMNLKISEED
HHHHHHHCCCCCCEEEEECCCCCCEEEEEEEHHHHCCCCCHHHHHHHHHHCCCEEECCCC
RIVLKENTCDFVGFSYYMSGVVSLNEDSLTEGNLVKVGKNKHLKENDWGQIDPVGLRILM
CEEEECCCCCCEEHHHHHHCEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHH
NRLYDRYQKPLFILENGVGFKEENPNLEMINDDYRIEYLKSHLQQVQKAVDDGVECIGYT
HHHHHHHCCCEEEEECCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHCCHHEEECC
MSPFDIVSHGTSEMAKRYGLIYVDQDDMGNGTKKRIPKKSYYFKEVCEKREI
CCHHHHHHCCHHHHHHHCCEEEEECCCCCCCHHHCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7883710; 7704263; 9384377 [H]