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The map label for this gene is ylbH [H]

Identifier: 50365010

GI number: 50365010

Start: 221258

End: 221827

Strand: Direct

Name: ylbH [H]

Synonym: Mfl194

Alternate gene names: 50365010

Gene position: 221258-221827 (Clockwise)

Preceding gene: 50365009

Following gene: 50365011

Centisome position: 27.89

GC content: 25.09

Gene sequence:

>570_bases
ATGAACGTAATATCAGGTAAGTATAAAGGGTTAAAATTAAATACATTAGAAGGTATGAATACAAGACCTACTCTAACAAG
AATTAAAGAAGATGCATTCAACATTATTGATAACTATTTTATCTTTGAAGGTAAAAAAAGTTTAGATATTTTTGGTGGAA
GTGGTGCTTTAACTATAGAGGGTTTAAGTAGAGGTATATCTTTTGGAATTGTTAATGATTATTCAAGAGATGCGATAAAA
GTTATTAAATCTAATTTAGCTAAAACTAAATCAACAAACTGAGAAATACATAATAAAGATTATTTAGAACTTCTTGATTT
TTTATGTTTTAAACACGAAAAATTTGACTTGGTATATATGGATCCTCCATTTGCCAAAATTGAATCATATGCACAAGTGT
TTACAAAATTACTTGAATTAAATTTATTAAATAACTGAGCAGTTATTATGATAGAGTCAGAAATGCCTTTAAATGAAGAA
GTTATTTCGCAATTTAAACTATTAAAATACAAAGATTACAATAAAAAACATCTATACATTATAAGATTGGAGAACAAAGA
TGAAGAATAA

Upstream 100 bases:

>100_bases
AATATTGAATTCTATTTTCACTACAAACAAGTCTTATAACTAGTTCTTTAATGTTTTTACAATATTATTACTATATAATA
TTAAATTAACAAGGAGTTAA

Downstream 100 bases:

>100_bases
AGGAAAAGTAATTATTATATCAGGACCAAGTGGTGTAGGAAAAGGGAGTGTTAATGGTGAACTACTTACTAACAAAGATT
TAAAATTAGAATATTCAGTT

Product: N6-adenine-specific methylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MNVISGKYKGLKLNTLEGMNTRPTLTRIKEDAFNIIDNYFIFEGKKSLDIFGGSGALTIEGLSRGISFGIVNDYSRDAIK
VIKSNLAKTKSTNWEIHNKDYLELLDFLCFKHEKFDLVYMDPPFAKIESYAQVFTKLLELNLLNNWAVIMIESEMPLNEE
VISQFKLLKYKDYNKKHLYIIRLENKDEE

Sequences:

>Translated_189_residues
MNVISGKYKGLKLNTLEGMNTRPTLTRIKEDAFNIIDNYFIFEGKKSLDIFGGSGALTIEGLSRGISFGIVNDYSRDAIK
VIKSNLAKTKSTN*EIHNKDYLELLDFLCFKHEKFDLVYMDPPFAKIESYAQVFTKLLELNLLNN*AVIMIESEMPLNEE
VISQFKLLKYKDYNKKHLYIIRLENKDEE
>Mature_189_residues
MNVISGKYKGLKLNTLEGMNTRPTLTRIKEDAFNIIDNYFIFEGKKSLDIFGGSGALTIEGLSRGISFGIVNDYSRDAIK
VIKSNLAKTKSTN*EIHNKDYLELLDFLCFKHEKFDLVYMDPPFAKIESYAQVFTKLLELNLLNN*AVIMIESEMPLNEE
VISQFKLLKYKDYNKKHLYIIRLENKDEE

Specific function: May catalyze the S-adenosyl-L-methionine-dependent methylation of a specific base in rRNA (Potential) [H]

COG id: COG0742

COG function: function code L; N6-adenine-specific methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmD family [H]

Homologues:

Organism=Escherichia coli, GI1789875, Length=156, Percent_Identity=31.4102564102564, Blast_Score=71, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004398 [H]

Pfam domain/function: PF03602 Cons_hypoth95 [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 21569; Mature: 21569

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVISGKYKGLKLNTLEGMNTRPTLTRIKEDAFNIIDNYFIFEGKKSLDIFGGSGALTIE
CCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCEEEEECCCCEEEECCCCEEEEE
GLSRGISFGIVNDYSRDAIKVIKSNLAKTKSTNEIHNKDYLELLDFLCFKHEKFDLVYMD
ECCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEC
PPFAKIESYAQVFTKLLELNLLNNAVIMIESEMPLNEEVISQFKLLKYKDYNKKHLYIIR
CCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEEE
LENKDEE
ECCCCCC
>Mature Secondary Structure
MNVISGKYKGLKLNTLEGMNTRPTLTRIKEDAFNIIDNYFIFEGKKSLDIFGGSGALTIE
CCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCEEEEECCCCEEEECCCCEEEEE
GLSRGISFGIVNDYSRDAIKVIKSNLAKTKSTNEIHNKDYLELLDFLCFKHEKFDLVYMD
ECCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEC
PPFAKIESYAQVFTKLLELNLLNNAVIMIESEMPLNEEVISQFKLLKYKDYNKKHLYIIR
CCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEEE
LENKDEE
ECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Methyltransferases Protein + DNA = Protein-DNA [C]

General reaction: Transferring one-carbon groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]