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The map label for this gene is infA

Identifier: 50364961

GI number: 50364961

Start: 159627

End: 159863

Strand: Direct

Name: infA

Synonym: Mfl146

Alternate gene names: 50364961

Gene position: 159627-159863 (Clockwise)

Preceding gene: 50364960

Following gene: 50364962

Centisome position: 20.12

GC content: 35.44

Gene sequence:

>237_bases
ATGGCAAAAGAAGCAGAAATGGAATTTGAAGGTACGGTTGTAGAAGTATTGCCTAATGCAAAATTCAAAGTACAACTGGA
AAACGACATTGTTATTGATGCACACGTGTCAGGTAAAATCCGAATGCATTACATTCGCATCTTACCTGGAGATAAAGTAA
CAGTCGTGATATCACCTTATGATATGACACGTGGAAGAATTACATATAGAAAAATTGCTAAAAAAGCAGAAGTGTAA

Upstream 100 bases:

>100_bases
AGCTGACAAGAGTATGACTGCTCACTTTGAACACACTATCTTAATTACTGATAGTGGTTATGAAGTATTAACTAAATCAA
AAAGATAGGAGTTGTAGTTT

Downstream 100 bases:

>100_bases
TTATAGAAAAAATCGACTTAAGTCGATTTAAATTGTTTAAATACAAAAGAACAAATACGGAGGTTACAGATGAAAGTAAG
ATCATCAGTCAAAAAAATTT

Product: translation initiation factor IF-1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 78; Mature: 77

Protein sequence:

>78_residues
MAKEAEMEFEGTVVEVLPNAKFKVQLENDIVIDAHVSGKIRMHYIRILPGDKVTVVISPYDMTRGRITYRKIAKKAEV

Sequences:

>Translated_78_residues
MAKEAEMEFEGTVVEVLPNAKFKVQLENDIVIDAHVSGKIRMHYIRILPGDKVTVVISPYDMTRGRITYRKIAKKAEV
>Mature_77_residues
AKEAEMEFEGTVVEVLPNAKFKVQLENDIVIDAHVSGKIRMHYIRILPGDKVTVVISPYDMTRGRITYRKIAKKAEV

Specific function: No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3

COG id: COG0361

COG function: function code J; Translation initiation factor 1 (IF-1)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1-like domain

Homologues:

Organism=Escherichia coli, GI1787110, Length=70, Percent_Identity=60, Blast_Score=96, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF1_MESFL (Q6F1X1)

Other databases:

- EMBL:   AE017263
- RefSeq:   YP_053386.1
- ProteinModelPortal:   Q6F1X1
- SMR:   Q6F1X1
- GeneID:   2897933
- GenomeReviews:   AE017263_GR
- KEGG:   mfl:Mfl146
- HOGENOM:   HBG286099
- OMA:   KMRMHFI
- ProtClustDB:   PRK00276
- BioCyc:   MFLO265311:MFL146-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00075
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR022967
- InterPro:   IPR006196
- InterPro:   IPR004368
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00316
- TIGRFAMs:   TIGR00008

Pfam domain/function: PF01176 eIF-1a; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 8889; Mature: 8757

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS50832 S1_IF1_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKEAEMEFEGTVVEVLPNAKFKVQLENDIVIDAHVSGKIRMHYIRILPGDKVTVVISPY
CCCCCCEEECCEEEEEECCCEEEEEECCCEEEEEECCCEEEEEEEEEECCCEEEEEECCC
DMTRGRITYRKIAKKAEV
CCCCCEEHHHHHHHHCCC
>Mature Secondary Structure 
AKEAEMEFEGTVVEVLPNAKFKVQLENDIVIDAHVSGKIRMHYIRILPGDKVTVVISPY
CCCCCEEECCEEEEEECCCEEEEEECCCEEEEEECCCEEEEEEEEEECCCEEEEEECCC
DMTRGRITYRKIAKKAEV
CCCCCEEHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA