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The map label for this gene is fabH [H]

Identifier: 50085221

GI number: 50085221

Start: 2087813

End: 2088934

Strand: Reverse

Name: fabH [H]

Synonym: ACIAD2101

Alternate gene names: 50085221

Gene position: 2088934-2087813 (Counterclockwise)

Preceding gene: 50085222

Following gene: 50085219

Centisome position: 58.05

GC content: 41.09

Gene sequence:

>1122_bases
ATGAAGGAGTTTTACATGGGCATTCGTATCACAGGTACAGGTTTGTACCATCCTGCAGAATCGATCAGTAATGAAGAGCT
GGTTGAAAGCCTTAATGCTTATGTAGAATATTATAATGCTGAAAATGCAGAAAAAATTGCAGCGGGCGAATTACCTGAGC
GCCTGGGTTCAAGTGCAGAATTTATCGAAAAAGCATCGGGTATAAAAAGTCGATATGTAATTGAAAAATCAGGTGTTCTT
GATCCTCAAAGATTACGTCCTCGTTTACAGGAGCGAACAGACGATGAGCTTTCTATTCAAGCCGAATGGGGAGTATTGGC
TGCGAAGCAGGCGATGGAAAATGCTAAAGTCACTGCTGAAGATATCGATGTCGTCATTTTAGCTTGCTCGAATATGCAGC
GTCCTTATCCAGCGGTTGCGGTTGAAATTCAGTCTGCGCTTGGTATTCAGGGCTACGCCTACGATATGAATGTTGCATGC
TCAGCCGCTACTTTTGGTTTAAAGCAAGCTTACGATGCCATTCAATCTGGTGCGCGCCGTGTTCTTTTGGTGAATGTCGA
GATTACTTCGGGACATACCGATTATCGTTCCAGAGACTGCCATTTTATTTTTGGTGATGTGGCTACAGCTTCCATTATTG
AGCAAACAGATACAAAAACTGGTTTTGAAATTTTGAATATACATTTGTTTACTCAGTTTTCCAACAACATCCGCAATAAC
TTTGGTTTCTTAAACCGTAGTGAGGATGCAACACGTGATGATAAACAGTTCAGGCAGGACGGACGAAAAGTATTTAAAGA
TGTGTGTCCACTGGTTGCAAAAATCATTACCGCCCAACTTGAAAAAAATCAGGTAAATCCACAAGACATAAAACGTTTCT
GGTTACATCAGGCCAATTTAAATATGAATCAGCTCATTGCTAAATTAGTATTGGGTAAAGAAGCAGAAGCTGAACGTACT
CCAATTATTCTGGATGAATTTGCCAATACCTCATCAGCAGGAGTCATTATTGCTTTACACAGAACAGGTGAAGAGGTGAG
TGAAGGCGAATTTGGTGTGATTTGTTCGTTTGGTGCGGGTTATTCGGTCGGTTCTTTGTTAGTACAAAAAAGAGTCGCTT
AG

Upstream 100 bases:

>100_bases
GTTATTTTCTCAACCCATGAAAACCAAGATGCCCGTTTCTGCTGCTCGACTGCAAAAGCTTTGGCAAGGTTTAGGCATAC
ATTAATTTACCCGCATTCTC

Downstream 100 bases:

>100_bases
ATTTTAAATATCGCTTGAACTAAAAAATACCTCCTTATTACAGGAGGTATTTTTTAATCTAATTTATTGGATAAAAGCTT
TTACACTGATGAGTGTACGA

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MKEFYMGIRITGTGLYHPAESISNEELVESLNAYVEYYNAENAEKIAAGELPERLGSSAEFIEKASGIKSRYVIEKSGVL
DPQRLRPRLQERTDDELSIQAEWGVLAAKQAMENAKVTAEDIDVVILACSNMQRPYPAVAVEIQSALGIQGYAYDMNVAC
SAATFGLKQAYDAIQSGARRVLLVNVEITSGHTDYRSRDCHFIFGDVATASIIEQTDTKTGFEILNIHLFTQFSNNIRNN
FGFLNRSEDATRDDKQFRQDGRKVFKDVCPLVAKIITAQLEKNQVNPQDIKRFWLHQANLNMNQLIAKLVLGKEAEAERT
PIILDEFANTSSAGVIIALHRTGEEVSEGEFGVICSFGAGYSVGSLLVQKRVA

Sequences:

>Translated_373_residues
MKEFYMGIRITGTGLYHPAESISNEELVESLNAYVEYYNAENAEKIAAGELPERLGSSAEFIEKASGIKSRYVIEKSGVL
DPQRLRPRLQERTDDELSIQAEWGVLAAKQAMENAKVTAEDIDVVILACSNMQRPYPAVAVEIQSALGIQGYAYDMNVAC
SAATFGLKQAYDAIQSGARRVLLVNVEITSGHTDYRSRDCHFIFGDVATASIIEQTDTKTGFEILNIHLFTQFSNNIRNN
FGFLNRSEDATRDDKQFRQDGRKVFKDVCPLVAKIITAQLEKNQVNPQDIKRFWLHQANLNMNQLIAKLVLGKEAEAERT
PIILDEFANTSSAGVIIALHRTGEEVSEGEFGVICSFGAGYSVGSLLVQKRVA
>Mature_373_residues
MKEFYMGIRITGTGLYHPAESISNEELVESLNAYVEYYNAENAEKIAAGELPERLGSSAEFIEKASGIKSRYVIEKSGVL
DPQRLRPRLQERTDDELSIQAEWGVLAAKQAMENAKVTAEDIDVVILACSNMQRPYPAVAVEIQSALGIQGYAYDMNVAC
SAATFGLKQAYDAIQSGARRVLLVNVEITSGHTDYRSRDCHFIFGDVATASIIEQTDTKTGFEILNIHLFTQFSNNIRNN
FGFLNRSEDATRDDKQFRQDGRKVFKDVCPLVAKIITAQLEKNQVNPQDIKRFWLHQANLNMNQLIAKLVLGKEAEAERT
PIILDEFANTSSAGVIIALHRTGEEVSEGEFGVICSFGAGYSVGSLLVQKRVA

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=328, Percent_Identity=27.7439024390244, Blast_Score=99, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 41358; Mature: 41358

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEFYMGIRITGTGLYHPAESISNEELVESLNAYVEYYNAENAEKIAAGELPERLGSSAE
CCCEEEEEEEEECCCCCCHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHCCHHH
FIEKASGIKSRYVIEKSGVLDPQRLRPRLQERTDDELSIQAEWGVLAAKQAMENAKVTAE
HHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCCCCC
DIDVVILACSNMQRPYPAVAVEIQSALGIQGYAYDMNVACSAATFGLKQAYDAIQSGARR
CCCEEEEEECCCCCCCCHHEEEEHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCE
VLLVNVEITSGHTDYRSRDCHFIFGDVATASIIEQTDTKTGFEILNIHLFTQFSNNIRNN
EEEEEEEEECCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCEEEEEEEEEEHHHHHHHHH
FGFLNRSEDATRDDKQFRQDGRKVFKDVCPLVAKIITAQLEKNQVNPQDIKRFWLHQANL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
NMNQLIAKLVLGKEAEAERTPIILDEFANTSSAGVIIALHRTGEEVSEGEFGVICSFGAG
CHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCC
YSVGSLLVQKRVA
CHHHHHHHHHCCC
>Mature Secondary Structure
MKEFYMGIRITGTGLYHPAESISNEELVESLNAYVEYYNAENAEKIAAGELPERLGSSAE
CCCEEEEEEEEECCCCCCHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHCCHHH
FIEKASGIKSRYVIEKSGVLDPQRLRPRLQERTDDELSIQAEWGVLAAKQAMENAKVTAE
HHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHCCCCCCC
DIDVVILACSNMQRPYPAVAVEIQSALGIQGYAYDMNVACSAATFGLKQAYDAIQSGARR
CCCEEEEEECCCCCCCCHHEEEEHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCE
VLLVNVEITSGHTDYRSRDCHFIFGDVATASIIEQTDTKTGFEILNIHLFTQFSNNIRNN
EEEEEEEEECCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCEEEEEEEEEEHHHHHHHHH
FGFLNRSEDATRDDKQFRQDGRKVFKDVCPLVAKIITAQLEKNQVNPQDIKRFWLHQANL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
NMNQLIAKLVLGKEAEAERTPIILDEFANTSSAGVIIALHRTGEEVSEGEFGVICSFGAG
CHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCEEEEEECCCC
YSVGSLLVQKRVA
CHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA