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The map label for this gene is yyxA [H]

Identifier: 49188298

GI number: 49188298

Start: 5200937

End: 5202112

Strand: Reverse

Name: yyxA [H]

Synonym: BAS5314

Alternate gene names: 49188298

Gene position: 5202112-5200937 (Counterclockwise)

Preceding gene: 49188299

Following gene: 49188297

Centisome position: 99.49

GC content: 38.78

Gene sequence:

>1176_bases
ATGTCCTTTATTGATGGAGAAAATTATCGTATGAAACGTGCAAGGAAAAAGAAGCATAAAGGTATTGTTATTTCTAGCAT
AGCAGGAACAATTGTAGGAGCTTCGTTATTTGCATTTGGAGCTCCTATATTTTCAAATGATACGGGCGCACTTCCGCAAG
CTGAAGCAAGTGGAAGTAATATGGCCGAAGCTCAAGGAATTAAACAGATTAGCTTTGTGGATGCTGTTGATCGTGCATCT
GAAGCTGTTGTTGGTATTATTAATATTCAACGAGATAATTTGTCAGAGGCAGATTCAGAAGCTGGCACAGGCTCAGGTGT
AATTTATAAGAAGACAAATGATCAAGCTTATATTGTAACGAATAATCATGTTGTTGCTGGGGCAAATCGTATTGAAGTAA
GTTTAAGTGACGGTAAGAAGGTTCCAGGAAAGGTATTAGGAACCGATGTAGTCACAGATTTGGCTGTACTAGAGATAGAT
GCAAAGCATGTGAAAAAGGTCATTGAGATTGGCGATTCTAATGCTGTTCGTAGAGGAGAACCAGTCATTGCGATTGGGAA
CCCGCTCGGGCTACAATTTTCTGGAACCGTCACACAAGGTATTATTTCGGCTAATGAGCGTATTGTTCCTGTAGATTTAG
ATCAAGATGGACATTATGATTGGCAAGTAGAAGTATTGCAAACAGACGCAGCAATTAATCCGGGTAATAGTGGTGGGGCG
CTTGTAAATGCAGCAGGTCAATTAATTGGTATTAACTCAATGAAAATTGCCGCAAAAGAAGTAGAAGGAATTGGTCTAGC
TATTCCAGTGACTAGAGCTGTTCCAATTATGAATGAATTAGAGAAGTACGGAAAAGTAAGAAGACCGTATGTTGGAATTG
AACTGAGATCATTAAATGAGATTCCAAACTATTATTGGTCAAAAACATTGCATTTACCAGGCAATGTAACAGAGGGAGTT
TGCATTTTAGATGTGAAAAGTCCTTCGCCAGGCACAGATGCTGGTTTACGAGAACACGATGTAATTGTAGCAGTAGATGG
AAAACCGGTTCGTGATATTATCGGATTCCGTACGGCCTTATATGATAAAAAAATTAATGATAAAATGACTCTTACGTTTT
ATCGTGGTACGAAACGAGCAACAACAACGGTTAAACTAGGCATTCAAAAGTATTAA

Upstream 100 bases:

>100_bases
AGATCCAAAAATGCCTACAAAAATTCAATACGTATAATTCTCCATTTTAGTAAACAATAAAGGTGAATATAGTTGTTTTC
AGGAAGATAGGTGAACAAAT

Downstream 100 bases:

>100_bases
AAACAGGAGGGCCTACCTCCTGTTTTCTATTGTAGAAAAGTGAGGTGAAGAATATGAATTTACCTTGTTGTTTAGAACAT
GTTGAATTAGCGTTAGATAT

Product: serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MSFIDGENYRMKRARKKKHKGIVISSIAGTIVGASLFAFGAPIFSNDTGALPQAEASGSNMAEAQGIKQISFVDAVDRAS
EAVVGIINIQRDNLSEADSEAGTGSGVIYKKTNDQAYIVTNNHVVAGANRIEVSLSDGKKVPGKVLGTDVVTDLAVLEID
AKHVKKVIEIGDSNAVRRGEPVIAIGNPLGLQFSGTVTQGIISANERIVPVDLDQDGHYDWQVEVLQTDAAINPGNSGGA
LVNAAGQLIGINSMKIAAKEVEGIGLAIPVTRAVPIMNELEKYGKVRRPYVGIELRSLNEIPNYYWSKTLHLPGNVTEGV
CILDVKSPSPGTDAGLREHDVIVAVDGKPVRDIIGFRTALYDKKINDKMTLTFYRGTKRATTTVKLGIQKY

Sequences:

>Translated_391_residues
MSFIDGENYRMKRARKKKHKGIVISSIAGTIVGASLFAFGAPIFSNDTGALPQAEASGSNMAEAQGIKQISFVDAVDRAS
EAVVGIINIQRDNLSEADSEAGTGSGVIYKKTNDQAYIVTNNHVVAGANRIEVSLSDGKKVPGKVLGTDVVTDLAVLEID
AKHVKKVIEIGDSNAVRRGEPVIAIGNPLGLQFSGTVTQGIISANERIVPVDLDQDGHYDWQVEVLQTDAAINPGNSGGA
LVNAAGQLIGINSMKIAAKEVEGIGLAIPVTRAVPIMNELEKYGKVRRPYVGIELRSLNEIPNYYWSKTLHLPGNVTEGV
CILDVKSPSPGTDAGLREHDVIVAVDGKPVRDIIGFRTALYDKKINDKMTLTFYRGTKRATTTVKLGIQKY
>Mature_390_residues
SFIDGENYRMKRARKKKHKGIVISSIAGTIVGASLFAFGAPIFSNDTGALPQAEASGSNMAEAQGIKQISFVDAVDRASE
AVVGIINIQRDNLSEADSEAGTGSGVIYKKTNDQAYIVTNNHVVAGANRIEVSLSDGKKVPGKVLGTDVVTDLAVLEIDA
KHVKKVIEIGDSNAVRRGEPVIAIGNPLGLQFSGTVTQGIISANERIVPVDLDQDGHYDWQVEVLQTDAAINPGNSGGAL
VNAAGQLIGINSMKIAAKEVEGIGLAIPVTRAVPIMNELEKYGKVRRPYVGIELRSLNEIPNYYWSKTLHLPGNVTEGVC
ILDVKSPSPGTDAGLREHDVIVAVDGKPVRDIIGFRTALYDKKINDKMTLTFYRGTKRATTTVKLGIQKY

Specific function: Unknown

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=284, Percent_Identity=33.8028169014084, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI24308541, Length=289, Percent_Identity=34.2560553633218, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI22129776, Length=319, Percent_Identity=30.7210031347962, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI7019477, Length=322, Percent_Identity=35.4037267080745, Blast_Score=120, Evalue=2e-27,
Organism=Escherichia coli, GI1789630, Length=378, Percent_Identity=35.1851851851852, Blast_Score=158, Evalue=6e-40,
Organism=Escherichia coli, GI1786356, Length=284, Percent_Identity=37.3239436619718, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1789629, Length=286, Percent_Identity=34.2657342657343, Blast_Score=141, Evalue=9e-35,
Organism=Drosophila melanogaster, GI24646839, Length=306, Percent_Identity=34.3137254901961, Blast_Score=132, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 41819; Mature: 41688

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFIDGENYRMKRARKKKHKGIVISSIAGTIVGASLFAFGAPIFSNDTGALPQAEASGSN
CCCCCCCCHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCC
MAEAQGIKQISFVDAVDRASEAVVGIINIQRDNLSEADSEAGTGSGVIYKKTNDQAYIVT
CHHHHCCCEEHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEEECCCCEEEEE
NNHVVAGANRIEVSLSDGKKVPGKVLGTDVVTDLAVLEIDAKHVKKVIEIGDSNAVRRGE
CCEEEECCCEEEEEECCCCCCCCHHCCHHHHHEEEEEEECHHHHHHHHHCCCCCCCCCCC
PVIAIGNPLGLQFSGTVTQGIISANERIVPVDLDQDGHYDWQVEVLQTDAAINPGNSGGA
CEEEECCCCCEEECCCHHHHHCCCCCEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCE
LVNAAGQLIGINSMKIAAKEVEGIGLAIPVTRAVPIMNELEKYGKVRRPYVGIELRSLNE
EEECCCCEEECCCCEEEHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCCEEEEEECCHHC
IPNYYWSKTLHLPGNVTEGVCILDVKSPSPGTDAGLREHDVIVAVDGKPVRDIIGFRTAL
CCCCHHCEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHH
YDKKINDKMTLTFYRGTKRATTTVKLGIQKY
HCCCCCCCEEEEEEECCCCEEEEEEEEEECC
>Mature Secondary Structure 
SFIDGENYRMKRARKKKHKGIVISSIAGTIVGASLFAFGAPIFSNDTGALPQAEASGSN
CCCCCCCHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCC
MAEAQGIKQISFVDAVDRASEAVVGIINIQRDNLSEADSEAGTGSGVIYKKTNDQAYIVT
CHHHHCCCEEHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEEECCCCEEEEE
NNHVVAGANRIEVSLSDGKKVPGKVLGTDVVTDLAVLEIDAKHVKKVIEIGDSNAVRRGE
CCEEEECCCEEEEEECCCCCCCCHHCCHHHHHEEEEEEECHHHHHHHHHCCCCCCCCCCC
PVIAIGNPLGLQFSGTVTQGIISANERIVPVDLDQDGHYDWQVEVLQTDAAINPGNSGGA
CEEEECCCCCEEECCCHHHHHCCCCCEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCE
LVNAAGQLIGINSMKIAAKEVEGIGLAIPVTRAVPIMNELEKYGKVRRPYVGIELRSLNE
EEECCCCEEECCCCEEEHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCCEEEEEECCHHC
IPNYYWSKTLHLPGNVTEGVCILDVKSPSPGTDAGLREHDVIVAVDGKPVRDIIGFRTAL
CCCCHHCEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHH
YDKKINDKMTLTFYRGTKRATTTVKLGIQKY
HCCCCCCCEEEEEEECCCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 8113162 [H]