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The map label for this gene is ykvZ [H]

Identifier: 49188239

GI number: 49188239

Start: 5136189

End: 5137166

Strand: Reverse

Name: ykvZ [H]

Synonym: BAS5254

Alternate gene names: 49188239

Gene position: 5137166-5136189 (Counterclockwise)

Preceding gene: 49188241

Following gene: 49188238

Centisome position: 98.25

GC content: 33.95

Gene sequence:

>978_bases
ATGACAAATATAAGAAAGATTGCTGAACTTGCTGGGGTATCTGTTTCAACTGTTTCACGTGTACTAAATAATCATCCTTA
TGTGAATGAACAGAAACGAAAAGAGATTTTAGCAATTATAGAAGAATTAAATTATACGCAAAATGTGAATGCAATTCATT
TAGTGAAAGGAAAAACGAATGTAATTGGCGTTTTATTACCGCACGTAAATGATCAATATTATAGCGCTATTATTGAAGGC
ATATCGAAGGAAACAGCAAAGAACAGTTATAATATGATGCTTTGTCAGACGAATTATAGTGAGGAAAAAGAATTAGAAAT
TTTGAATATGTTAAAAATGAAAAAGCTTGATGGGGTTATTATATGTTCCCGGACAAATAGTAAGGAAAAGCTTGAAGAAT
ATACGAAATTTGGTCCAATCGTTATGTGTGAGGAAATAGATTCAAAATACATTTCAAGTGTACATGTTGATTACTATAAA
GTGTTTTCACAAGGGGTGAAAAACTTAATAGATGCTGGTCATACACGTATTGGGTATTGCATTGGAAGAAGTAATAGCAT
TAATAGCCAAAGAAGAAAACAAGCATATGAAGATTCACTTCAACAGATTGCTGTAACACCGTTAGAGACCTGGAAGTTTA
AAGGCTGTTTTACGGTGGAAGACGGGCGTAATGTAATTAGGGAATGGGCCTGTATGTCAGTAAAGCCAACTGCGTTTCTT
GTATCTTGTAACCATATTGCAGCGGGAATGGTAACGGAGGCGAAAAAACAAGGAATTCGTATTCCAGAAGATATTACGAT
TATTGGTTGTGATGATCAAGATGTAGCAGACATTTTAGGTATTACGACGATTTCATATTCTAGTAAAAATGTTGGCGTGA
AGGCATTTGAATTATTATATGAAAAGATTAATGATGAGCAAATAGATGTAAAGCACGTGGAGTTATTGCCAGAATTCGTA
AAAAGGGAAACGACATAA

Upstream 100 bases:

>100_bases
ATAGTTGTATATCCTTTCAAAATGTATTTGCTAGGAAAGGATATATTGTGGAAAGCTTACCAGGTCAAGGGAGAATTTTT
GCAGGGAAGGGGAAAATGAG

Downstream 100 bases:

>100_bases
TAGATAAGGTGTGAAAATCGCTTTTCAAAATTGCGTTTGGTATAATTATGGACAATCTATGAGGGCTAAAAGGGGTTTTG
ATATGAGATCAAAAGTGGTA

Product: LacI family sugar-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MTNIRKIAELAGVSVSTVSRVLNNHPYVNEQKRKEILAIIEELNYTQNVNAIHLVKGKTNVIGVLLPHVNDQYYSAIIEG
ISKETAKNSYNMMLCQTNYSEEKELEILNMLKMKKLDGVIICSRTNSKEKLEEYTKFGPIVMCEEIDSKYISSVHVDYYK
VFSQGVKNLIDAGHTRIGYCIGRSNSINSQRRKQAYEDSLQQIAVTPLETWKFKGCFTVEDGRNVIREWACMSVKPTAFL
VSCNHIAAGMVTEAKKQGIRIPEDITIIGCDDQDVADILGITTISYSSKNVGVKAFELLYEKINDEQIDVKHVELLPEFV
KRETT

Sequences:

>Translated_325_residues
MTNIRKIAELAGVSVSTVSRVLNNHPYVNEQKRKEILAIIEELNYTQNVNAIHLVKGKTNVIGVLLPHVNDQYYSAIIEG
ISKETAKNSYNMMLCQTNYSEEKELEILNMLKMKKLDGVIICSRTNSKEKLEEYTKFGPIVMCEEIDSKYISSVHVDYYK
VFSQGVKNLIDAGHTRIGYCIGRSNSINSQRRKQAYEDSLQQIAVTPLETWKFKGCFTVEDGRNVIREWACMSVKPTAFL
VSCNHIAAGMVTEAKKQGIRIPEDITIIGCDDQDVADILGITTISYSSKNVGVKAFELLYEKINDEQIDVKHVELLPEFV
KRETT
>Mature_324_residues
TNIRKIAELAGVSVSTVSRVLNNHPYVNEQKRKEILAIIEELNYTQNVNAIHLVKGKTNVIGVLLPHVNDQYYSAIIEGI
SKETAKNSYNMMLCQTNYSEEKELEILNMLKMKKLDGVIICSRTNSKEKLEEYTKFGPIVMCEEIDSKYISSVHVDYYKV
FSQGVKNLIDAGHTRIGYCIGRSNSINSQRRKQAYEDSLQQIAVTPLETWKFKGCFTVEDGRNVIREWACMSVKPTAFLV
SCNHIAAGMVTEAKKQGIRIPEDITIIGCDDQDVADILGITTISYSSKNVGVKAFELLYEKINDEQIDVKHVELLPEFVK
RETT

Specific function: Transcriptional Repressor For The Ribose Rbsdacbk Operon. Rbsr Binds To A Region Of Perfect Dyad Symmetry Spanning The Rbs Operon Transcriptional Start Site. The Affinity For The Rbs Operator Is Reduced By Addition Of Ribose, Consistent With Ribose Being

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=331, Percent_Identity=26.8882175226586, Blast_Score=138, Evalue=4e-34,
Organism=Escherichia coli, GI1787948, Length=330, Percent_Identity=26.6666666666667, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1790369, Length=311, Percent_Identity=26.0450160771704, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1788474, Length=329, Percent_Identity=27.0516717325228, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1789202, Length=285, Percent_Identity=26.3157894736842, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI48994940, Length=317, Percent_Identity=24.9211356466877, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1789068, Length=281, Percent_Identity=25.6227758007117, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789456, Length=320, Percent_Identity=26.5625, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1786540, Length=326, Percent_Identity=25.4601226993865, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1787580, Length=313, Percent_Identity=24.6006389776358, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1790715, Length=321, Percent_Identity=22.4299065420561, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1787906, Length=212, Percent_Identity=25, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1786268, Length=316, Percent_Identity=18.3544303797468, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790689, Length=195, Percent_Identity=24.1025641025641, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36787; Mature: 36656

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNIRKIAELAGVSVSTVSRVLNNHPYVNEQKRKEILAIIEELNYTQNVNAIHLVKGKTN
CCHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCC
VIGVLLPHVNDQYYSAIIEGISKETAKNSYNMMLCQTNYSEEKELEILNMLKMKKLDGVI
EEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCEE
ICSRTNSKEKLEEYTKFGPIVMCEEIDSKYISSVHVDYYKVFSQGVKNLIDAGHTRIGYC
EEECCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
IGRSNSINSQRRKQAYEDSLQQIAVTPLETWKFKGCFTVEDGRNVIREWACMSVKPTAFL
ECCCCCCCHHHHHHHHHHHHHHHCCCCHHHEEECCEEEECCHHHHHHHHHHCCCCCCEEE
VSCNHIAAGMVTEAKKQGIRIPEDITIIGCDDQDVADILGITTISYSSKNVGVKAFELLY
EECCHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHEEEECCCCCCHHHHHHHH
EKINDEQIDVKHVELLPEFVKRETT
HHHCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TNIRKIAELAGVSVSTVSRVLNNHPYVNEQKRKEILAIIEELNYTQNVNAIHLVKGKTN
CHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCC
VIGVLLPHVNDQYYSAIIEGISKETAKNSYNMMLCQTNYSEEKELEILNMLKMKKLDGVI
EEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCEE
ICSRTNSKEKLEEYTKFGPIVMCEEIDSKYISSVHVDYYKVFSQGVKNLIDAGHTRIGYC
EEECCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
IGRSNSINSQRRKQAYEDSLQQIAVTPLETWKFKGCFTVEDGRNVIREWACMSVKPTAFL
ECCCCCCCHHHHHHHHHHHHHHHCCCCHHHEEECCEEEECCHHHHHHHHHHCCCCCCEEE
VSCNHIAAGMVTEAKKQGIRIPEDITIIGCDDQDVADILGITTISYSSKNVGVKAFELLY
EECCHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHEEEECCCCCCHHHHHHHH
EKINDEQIDVKHVELLPEFVKRETT
HHHCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]