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The map label for this gene is uvsE [H]

Identifier: 49188182

GI number: 49188182

Start: 5078382

End: 5079359

Strand: Direct

Name: uvsE [H]

Synonym: BAS5196

Alternate gene names: 49188182

Gene position: 5078382-5079359 (Clockwise)

Preceding gene: 49188181

Following gene: 49188183

Centisome position: 97.13

GC content: 34.05

Gene sequence:

>978_bases
ATGCATAAAGGATGTGTATTCATTATGATTATGCGGTTCGGATATGTCTCACATGCAATGGCACTCTGGGACTGCTCTCC
GGCTAAAACGATAACATTTACAAGCTTTCAAAAGCTCAGTAAACAAGAGCGAGAAGATAAATTATACGATGTTACAAAAC
AAAATCTTGAGCATACAATACGTATTCTCCATTACAATATAGCTCATGAAATTCCGTTATATCGCTTGTCTTCTTCCATC
GTCCCACTTGCAACACATCCCGAAGTCGAGTTTGATTATATCGGGGCATTTACACCGCTTTGGCGTAAAATTGGGGCATT
AATTAAAGAACATAATTTAAGAATAAGTTTTCATCCAAATCAATTTACACTATTTACAAGCGACAAACCACATATTACGA
CTAACGCTATTACAGATATGACCTATCATTATAAAGTATTAGATGCAATAGGCATTGCAGATTCTTCTTATATTAACATC
CATGTAGGTGGGGCCTACGGAAATAAAGAAAAAGCAATCGAGCGTTTCCATGAAAACATAAAAAAACTTCCTGCACATAT
AAAAAAGCAAATGACACTTGAAAATGATGATAAAACATATACAACAGCTGAAACGTTATCTATTTGCCAAAAAGAAAAGA
TCCCATTCGTATTTGATTATCACCATCACATGGCAAATCTTTGCGAGGAACCGTTAGAAGAGTTGCTTCCTGCAATTTTT
GAAACTTGGTCACATACAAATATCGTTCCTAAAGTTCACATTTCCTCTCCTAAATCAAAAAAAGAATTTAGGGCTCACGC
GGAATATATTGATTTAGAATTTATTAAACCTTTCTTACACGTTGCAAAAAAAATCAATCATAATTTCGATATTATGATTG
AAAGTAAACAGAAAGATTTAGCGATGCTGCAATTCATACAGGAATTATCCTCTATAAGAGGGATAAAAAGAATAAGTAGC
TCAACATTACAATGGTAA

Upstream 100 bases:

>100_bases
CATCATTACTTTCCTTTAAAGATGTTAGCCCGCATTCTCTTATTGATAGAGGAAAAGAATGGATAGGAACAATACTCGCT
TTCTTCCTATAGGAAAGATA

Downstream 100 bases:

>100_bases
ATTGTAATGTTGAGCTATTTTTTTCAAAAAAAGTAATTTTTTAGTAAAAAACACCCTATTTTATATGCTATGATTGGAAT
TAGCATTTTCCACCTGTGAT

Product: putative UV damage endonuclease

Products: NA

Alternate protein names: UV-endonuclease; UVED [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MHKGCVFIMIMRFGYVSHAMALWDCSPAKTITFTSFQKLSKQEREDKLYDVTKQNLEHTIRILHYNIAHEIPLYRLSSSI
VPLATHPEVEFDYIGAFTPLWRKIGALIKEHNLRISFHPNQFTLFTSDKPHITTNAITDMTYHYKVLDAIGIADSSYINI
HVGGAYGNKEKAIERFHENIKKLPAHIKKQMTLENDDKTYTTAETLSICQKEKIPFVFDYHHHMANLCEEPLEELLPAIF
ETWSHTNIVPKVHISSPKSKKEFRAHAEYIDLEFIKPFLHVAKKINHNFDIMIESKQKDLAMLQFIQELSSIRGIKRISS
STLQW

Sequences:

>Translated_325_residues
MHKGCVFIMIMRFGYVSHAMALWDCSPAKTITFTSFQKLSKQEREDKLYDVTKQNLEHTIRILHYNIAHEIPLYRLSSSI
VPLATHPEVEFDYIGAFTPLWRKIGALIKEHNLRISFHPNQFTLFTSDKPHITTNAITDMTYHYKVLDAIGIADSSYINI
HVGGAYGNKEKAIERFHENIKKLPAHIKKQMTLENDDKTYTTAETLSICQKEKIPFVFDYHHHMANLCEEPLEELLPAIF
ETWSHTNIVPKVHISSPKSKKEFRAHAEYIDLEFIKPFLHVAKKINHNFDIMIESKQKDLAMLQFIQELSSIRGIKRISS
STLQW
>Mature_325_residues
MHKGCVFIMIMRFGYVSHAMALWDCSPAKTITFTSFQKLSKQEREDKLYDVTKQNLEHTIRILHYNIAHEIPLYRLSSSI
VPLATHPEVEFDYIGAFTPLWRKIGALIKEHNLRISFHPNQFTLFTSDKPHITTNAITDMTYHYKVLDAIGIADSSYINI
HVGGAYGNKEKAIERFHENIKKLPAHIKKQMTLENDDKTYTTAETLSICQKEKIPFVFDYHHHMANLCEEPLEELLPAIF
ETWSHTNIVPKVHISSPKSKKEFRAHAEYIDLEFIKPFLHVAKKINHNFDIMIESKQKDLAMLQFIQELSSIRGIKRISS
STLQW

Specific function: Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion [H]

COG id: COG4294

COG function: function code L; UV damage repair endonuclease

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uve1/uvsE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004601
- InterPro:   IPR013022 [H]

Pfam domain/function: PF03851 UvdE [H]

EC number: NA

Molecular weight: Translated: 37795; Mature: 37795

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKGCVFIMIMRFGYVSHAMALWDCSPAKTITFTSFQKLSKQEREDKLYDVTKQNLEHTI
CCCCCEEHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RILHYNIAHEIPLYRLSSSIVPLATHPEVEFDYIGAFTPLWRKIGALIKEHNLRISFHPN
HHHEEHHHHCCCHHHHCCCCEEEECCCCCCCHHHCCHHHHHHHHHHHHHHCCEEEEECCC
QFTLFTSDKPHITTNAITDMTYHYKVLDAIGIADSSYINIHVGGAYGNKEKAIERFHENI
EEEEEECCCCCEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHH
KKLPAHIKKQMTLENDDKTYTTAETLSICQKEKIPFVFDYHHHMANLCEEPLEELLPAIF
HHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
ETWSHTNIVPKVHISSPKSKKEFRAHAEYIDLEFIKPFLHVAKKINHNFDIMIESKQKDL
HHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHH
AMLQFIQELSSIRGIKRISSSTLQW
HHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MHKGCVFIMIMRFGYVSHAMALWDCSPAKTITFTSFQKLSKQEREDKLYDVTKQNLEHTI
CCCCCEEHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RILHYNIAHEIPLYRLSSSIVPLATHPEVEFDYIGAFTPLWRKIGALIKEHNLRISFHPN
HHHEEHHHHCCCHHHHCCCCEEEECCCCCCCHHHCCHHHHHHHHHHHHHHCCEEEEECCC
QFTLFTSDKPHITTNAITDMTYHYKVLDAIGIADSSYINIHVGGAYGNKEKAIERFHENI
EEEEEECCCCCEEHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHH
KKLPAHIKKQMTLENDDKTYTTAETLSICQKEKIPFVFDYHHHMANLCEEPLEELLPAIF
HHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
ETWSHTNIVPKVHISSPKSKKEFRAHAEYIDLEFIKPFLHVAKKINHNFDIMIESKQKDL
HHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHH
AMLQFIQELSSIRGIKRISSSTLQW
HHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA