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The map label for this gene is nuoC [H]

Identifier: 49188134

GI number: 49188134

Start: 5032186

End: 5033139

Strand: Reverse

Name: nuoC [H]

Synonym: BAS5148

Alternate gene names: 49188134

Gene position: 5033139-5032186 (Counterclockwise)

Preceding gene: 49188135

Following gene: 49188133

Centisome position: 96.26

GC content: 44.76

Gene sequence:

>954_bases
ATGAGTGATCCTAACAAAGACTTAGAGGATTTAAAAAGAGAAGCGGCTAGGCGTGCGAAAGAAGAGGCGAGAAAGCGTCT
CGTTGCGAAACATGGTGTGGAAATAAGTAAACTTGAGGAAGAAAATCGCGAAAAAGAGAAAGCGCTACCAAAAAATGACG
ATATGACTATAGAAGAAGCAAAACGACGTGCAGCCGCGGCCGCAAAAGCAAAAGCAGCGGCGTTAGCGAAGCAGAAAAGA
GAAGGAATAGAAGAAGTAACGGAAGAGGAAAAGGTCAAAGCGAAGGCAGCGGCAGCCGCGAAAGCAAAAGCAGCAGCGTT
AGCGAAGCAGAAAGCATCGCAAGGTAATGGAGATTCGGGAGATGAAAAGGCGAAGGCAATTGCAGCAGCAAAGGCAAAAG
CGGCAGCGGCTGCAAGAGCGAAGACAAAGGGTGCTGAAGGTAAGAAGGAAGAGGAGCTGAAGCAGGAAGAGCCATCCGTG
AATGAACCGTATTTAAATCAGTATGTTGAAGTTATTAAGGGAAAGATAGGAGAGGATATATTAGTAGATTTCTACATTAA
TAAACTGTCAAAAGATGTACCAACTCTTGTGGTGGAACCTGCAAAATATTATGAAGTAATGGAGTTACTGCGATTCCATG
AGGGACTTGCATTTGATTATATGTCAGAGCTACATGCGACGGATTTTGTGACACATATGGAAGTGTATGTTCATTTATTT
TCATATGGAAAGAAACAGTCAGTAGCGGTGAAGGTGAAGCTGGATAGGGAAGCGCCGCAAGTGGAATCGGTGACAGCGCT
TTGGAAAGGAGCGGACTGGCCAGAGCGGGAAGCGTATGATTTGCTTGGTATTGTATTTAAGGGGCATCCAAATTTATCAC
GTATTTTAATGCCTGATGATTGGGTAGGGCACCCGCTTAGGAAAGATTATGAACCGTATGATGTGGAGGTGTAG

Upstream 100 bases:

>100_bases
CTGGTTGCCCACCAAATCCTGCAGCTTTAATTTATGGAATTAATAAATTAAAAGAAAAAATTCGTTACGAAGCAAAGACT
GGAAAGCAGGTGACGAATAA

Downstream 100 bases:

>100_bases
CTAAATGATCCGTACGGAAGAAATGCTTTTGAATGTAGGTCCTCAGCATCCGAGTACCCACGGTGTGTTCAGGCTTGTTA
TTAAGATTGACGGGGAAATT

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MSDPNKDLEDLKREAARRAKEEARKRLVAKHGVEISKLEEENREKEKALPKNDDMTIEEAKRRAAAAAKAKAAALAKQKR
EGIEEVTEEEKVKAKAAAAAKAKAAALAKQKASQGNGDSGDEKAKAIAAAKAKAAAAARAKTKGAEGKKEEELKQEEPSV
NEPYLNQYVEVIKGKIGEDILVDFYINKLSKDVPTLVVEPAKYYEVMELLRFHEGLAFDYMSELHATDFVTHMEVYVHLF
SYGKKQSVAVKVKLDREAPQVESVTALWKGADWPEREAYDLLGIVFKGHPNLSRILMPDDWVGHPLRKDYEPYDVEV

Sequences:

>Translated_317_residues
MSDPNKDLEDLKREAARRAKEEARKRLVAKHGVEISKLEEENREKEKALPKNDDMTIEEAKRRAAAAAKAKAAALAKQKR
EGIEEVTEEEKVKAKAAAAAKAKAAALAKQKASQGNGDSGDEKAKAIAAAKAKAAAAARAKTKGAEGKKEEELKQEEPSV
NEPYLNQYVEVIKGKIGEDILVDFYINKLSKDVPTLVVEPAKYYEVMELLRFHEGLAFDYMSELHATDFVTHMEVYVHLF
SYGKKQSVAVKVKLDREAPQVESVTALWKGADWPEREAYDLLGIVFKGHPNLSRILMPDDWVGHPLRKDYEPYDVEV
>Mature_316_residues
SDPNKDLEDLKREAARRAKEEARKRLVAKHGVEISKLEEENREKEKALPKNDDMTIEEAKRRAAAAAKAKAAALAKQKRE
GIEEVTEEEKVKAKAAAAAKAKAAALAKQKASQGNGDSGDEKAKAIAAAKAKAAAAARAKTKGAEGKKEEELKQEEPSVN
EPYLNQYVEVIKGKIGEDILVDFYINKLSKDVPTLVVEPAKYYEVMELLRFHEGLAFDYMSELHATDFVTHMEVYVHLFS
YGKKQSVAVKVKLDREAPQVESVTALWKGADWPEREAYDLLGIVFKGHPNLSRILMPDDWVGHPLRKDYEPYDVEV

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=217, Percent_Identity=27.1889400921659, Blast_Score=75, Evalue=7e-14,
Organism=Escherichia coli, GI145693162, Length=87, Percent_Identity=48.2758620689655, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789076, Length=130, Percent_Identity=34.6153846153846, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71990788, Length=118, Percent_Identity=36.4406779661017, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI32563621, Length=118, Percent_Identity=36.4406779661017, Blast_Score=81, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 35356; Mature: 35225

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDPNKDLEDLKREAARRAKEEARKRLVAKHGVEISKLEEENREKEKALPKNDDMTIEEA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHH
KRRAAAAAKAKAAALAKQKREGIEEVTEEEKVKAKAAAAAKAKAAALAKQKASQGNGDSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DEKAKAIAAAKAKAAAAARAKTKGAEGKKEEELKQEEPSVNEPYLNQYVEVIKGKIGEDI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHH
LVDFYINKLSKDVPTLVVEPAKYYEVMELLRFHEGLAFDYMSELHATDFVTHMEVYVHLF
HHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
SYGKKQSVAVKVKLDREAPQVESVTALWKGADWPEREAYDLLGIVFKGHPNLSRILMPDD
HCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHEECCCCCCEEECCCC
WVGHPLRKDYEPYDVEV
CCCCCHHCCCCCCCCCC
>Mature Secondary Structure 
SDPNKDLEDLKREAARRAKEEARKRLVAKHGVEISKLEEENREKEKALPKNDDMTIEEA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHH
KRRAAAAAKAKAAALAKQKREGIEEVTEEEKVKAKAAAAAKAKAAALAKQKASQGNGDSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DEKAKAIAAAKAKAAAAARAKTKGAEGKKEEELKQEEPSVNEPYLNQYVEVIKGKIGEDI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCHH
LVDFYINKLSKDVPTLVVEPAKYYEVMELLRFHEGLAFDYMSELHATDFVTHMEVYVHLF
HHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
SYGKKQSVAVKVKLDREAPQVESVTALWKGADWPEREAYDLLGIVFKGHPNLSRILMPDD
HCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHEECCCCCCEEECCCC
WVGHPLRKDYEPYDVEV
CCCCCHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA