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The map label for this gene is galE [H]

Identifier: 49188100

GI number: 49188100

Start: 4993412

End: 4994404

Strand: Reverse

Name: galE [H]

Synonym: BAS5114

Alternate gene names: 49188100

Gene position: 4994404-4993412 (Counterclockwise)

Preceding gene: 49188101

Following gene: 49188099

Centisome position: 95.52

GC content: 39.17

Gene sequence:

>993_bases
ATGAATTCAATTCTAATCTGCGGCGGAGCTGGTTATATCGGTTCTCACGCTGTGAAAAAATTAGTAGACGAAGGTTTATC
TGTAGTAGTAGTAGATAACTTACAAACTGGTCATGAGGATGCAATTACGGAAGGTGCGAAGTTTTATAATGGCGACCTTC
GTGATAAAGCATTTTTAAGAGATGTTTTTACACAAGAAAATATTGAGGCTGTTATGCATTTCGCAGCTGATTCTTTAGTT
GGAGTTAGTATGGAGAAGCCTCTTCAATATTATAATAACAATGTGTATGGTGCACTTTGCTTATTAGAGGTAATGGATGA
GTTTAAGGTAGATAAGTTTATTTTCTCTTCTACTGCGGCGACGTATGGTGAGGTAGATGTAGACCTTATTACTGAGGAAA
CGATGACAAATCCAACGAATACGTATGGAGAAACGAAGTTAGCAATCGAGAAGATGCTTCATTGGTATAGCCAAGCTTCT
AATTTACGTTATAAGATTTTCAGATACTTTAACGTGGCTGGTGCAACTCCAAATGGTATTATCGGGGAAGATCACCGTCC
GGAGACGCATTTAATTCCTCTTGTATTGCAAGTGGCGTTAGGTCAACGTGAGAAGATTATGATGTTTGGTGATGACTATA
ATACACCAGATGGTACTTGTATTCGTGATTATATTCATGTTGAAGATTTAGTGGCAGCTCACTTCTTAGGACTTAAGGAC
CTACAGAACGGTGGAGAGAGTGATTTCTATAACTTAGGAAATGGTAATGGTTTCAGTGTAAAAGAAATCGTTGATGCAGT
TCGTGAAGTTACAAATCATGAAATTCCTGCTGAAGTAGCACCACGTCGTGCGGGAGATCCAGCACGTTTAGTTGCTTCTT
CTCAGAAAGCGAAAGAGAAGTTAGGCTGGGATCCTCGGTATGTAAATGTGAAGACAATCATTGAGCATGCTTGGAATTGG
CATCAGAAGCAACCTAATGGGTATGAGAAATAA

Upstream 100 bases:

>100_bases
TTGCGAAGTAATAAAGGTACACAAAAGGTATACGAGCAATCGTATACCTTTTATAATAAGAGAGTGAATAAGAAATCCTA
ATATATGTAGGAGGAAGACT

Downstream 100 bases:

>100_bases
AGTGAAACTTTAATAAGTGAAAGAGGGGTATTGTCGTTCAATATATGTTCGACAATACCCTCTCTTTTTTTGTATGATTT
TTGCTATACTAAACTGTACT

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MNSILICGGAGYIGSHAVKKLVDEGLSVVVVDNLQTGHEDAITEGAKFYNGDLRDKAFLRDVFTQENIEAVMHFAADSLV
GVSMEKPLQYYNNNVYGALCLLEVMDEFKVDKFIFSSTAATYGEVDVDLITEETMTNPTNTYGETKLAIEKMLHWYSQAS
NLRYKIFRYFNVAGATPNGIIGEDHRPETHLIPLVLQVALGQREKIMMFGDDYNTPDGTCIRDYIHVEDLVAAHFLGLKD
LQNGGESDFYNLGNGNGFSVKEIVDAVREVTNHEIPAEVAPRRAGDPARLVASSQKAKEKLGWDPRYVNVKTIIEHAWNW
HQKQPNGYEK

Sequences:

>Translated_330_residues
MNSILICGGAGYIGSHAVKKLVDEGLSVVVVDNLQTGHEDAITEGAKFYNGDLRDKAFLRDVFTQENIEAVMHFAADSLV
GVSMEKPLQYYNNNVYGALCLLEVMDEFKVDKFIFSSTAATYGEVDVDLITEETMTNPTNTYGETKLAIEKMLHWYSQAS
NLRYKIFRYFNVAGATPNGIIGEDHRPETHLIPLVLQVALGQREKIMMFGDDYNTPDGTCIRDYIHVEDLVAAHFLGLKD
LQNGGESDFYNLGNGNGFSVKEIVDAVREVTNHEIPAEVAPRRAGDPARLVASSQKAKEKLGWDPRYVNVKTIIEHAWNW
HQKQPNGYEK
>Mature_330_residues
MNSILICGGAGYIGSHAVKKLVDEGLSVVVVDNLQTGHEDAITEGAKFYNGDLRDKAFLRDVFTQENIEAVMHFAADSLV
GVSMEKPLQYYNNNVYGALCLLEVMDEFKVDKFIFSSTAATYGEVDVDLITEETMTNPTNTYGETKLAIEKMLHWYSQAS
NLRYKIFRYFNVAGATPNGIIGEDHRPETHLIPLVLQVALGQREKIMMFGDDYNTPDGTCIRDYIHVEDLVAAHFLGLKD
LQNGGESDFYNLGNGNGFSVKEIVDAVREVTNHEIPAEVAPRRAGDPARLVASSQKAKEKLGWDPRYVNVKTIIEHAWNW
HQKQPNGYEK

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=341, Percent_Identity=37.5366568914956, Blast_Score=225, Evalue=4e-59,
Organism=Homo sapiens, GI56118217, Length=341, Percent_Identity=37.5366568914956, Blast_Score=225, Evalue=4e-59,
Organism=Homo sapiens, GI189083684, Length=341, Percent_Identity=37.5366568914956, Blast_Score=225, Evalue=4e-59,
Organism=Homo sapiens, GI7657641, Length=336, Percent_Identity=27.9761904761905, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI42516563, Length=307, Percent_Identity=26.0586319218241, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1786974, Length=335, Percent_Identity=35.8208955223881, Blast_Score=220, Evalue=8e-59,
Organism=Escherichia coli, GI48994969, Length=337, Percent_Identity=29.080118694362, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788353, Length=337, Percent_Identity=27.299703264095, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790049, Length=276, Percent_Identity=30.0724637681159, Blast_Score=86, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71982035, Length=345, Percent_Identity=36.8115942028986, Blast_Score=227, Evalue=6e-60,
Organism=Caenorhabditis elegans, GI71982038, Length=347, Percent_Identity=36.5994236311239, Blast_Score=226, Evalue=9e-60,
Organism=Caenorhabditis elegans, GI115532424, Length=325, Percent_Identity=26.7692307692308, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17539532, Length=313, Percent_Identity=24.6006389776358, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17568069, Length=324, Percent_Identity=26.5432098765432, Blast_Score=71, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=344, Percent_Identity=40.9883720930233, Blast_Score=251, Evalue=2e-67,
Organism=Drosophila melanogaster, GI19923002, Length=349, Percent_Identity=39.541547277937, Blast_Score=229, Evalue=2e-60,
Organism=Drosophila melanogaster, GI21356223, Length=310, Percent_Identity=24.5161290322581, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36914; Mature: 36914

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSILICGGAGYIGSHAVKKLVDEGLSVVVVDNLQTGHEDAITEGAKFYNGDLRDKAFLR
CCCEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHCCCHHCCCCCCHHHHHH
DVFTQENIEAVMHFAADSLVGVSMEKPLQYYNNNVYGALCLLEVMDEFKVDKFIFSSTAA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
TYGEVDVDLITEETMTNPTNTYGETKLAIEKMLHWYSQASNLRYKIFRYFNVAGATPNGI
CCCCCEEEEECHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCC
IGEDHRPETHLIPLVLQVALGQREKIMMFGDDYNTPDGTCIRDYIHVEDLVAAHFLGLKD
CCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LQNGGESDFYNLGNGNGFSVKEIVDAVREVTNHEIPAEVAPRRAGDPARLVASSQKAKEK
HCCCCCCCCEECCCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHH
LGWDPRYVNVKTIIEHAWNWHQKQPNGYEK
CCCCCCEEHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNSILICGGAGYIGSHAVKKLVDEGLSVVVVDNLQTGHEDAITEGAKFYNGDLRDKAFLR
CCCEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHCCCHHCCCCCCHHHHHH
DVFTQENIEAVMHFAADSLVGVSMEKPLQYYNNNVYGALCLLEVMDEFKVDKFIFSSTAA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
TYGEVDVDLITEETMTNPTNTYGETKLAIEKMLHWYSQASNLRYKIFRYFNVAGATPNGI
CCCCCEEEEECHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCC
IGEDHRPETHLIPLVLQVALGQREKIMMFGDDYNTPDGTCIRDYIHVEDLVAAHFLGLKD
CCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LQNGGESDFYNLGNGNGFSVKEIVDAVREVTNHEIPAEVAPRRAGDPARLVASSQKAKEK
HCCCCCCCCEECCCCCCCCHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHH
LGWDPRYVNVKTIIEHAWNWHQKQPNGYEK
CCCCCCEEHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]