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The map label for this gene is mnaA [H]

Identifier: 49188034

GI number: 49188034

Start: 4920849

End: 4921964

Strand: Reverse

Name: mnaA [H]

Synonym: BAS5048

Alternate gene names: 49188034

Gene position: 4921964-4920849 (Counterclockwise)

Preceding gene: 49188035

Following gene: 49188031

Centisome position: 94.13

GC content: 39.34

Gene sequence:

>1116_bases
ATGACTGAACGTTTAAAAGTAATGACAATTTTCGGGACACGTCCAGAAGCAATTAAAATGGCACCTCTTGTATTAGAGTT
GCAAAAGCATCCAGAGAAAATTGAGTCGATTGTGACTGTAACAGCGCAACATCGTCAAATGTTAGACCAAGTATTAAGTA
TCTTTGGAATTACACCAGATTTCGATTTGAATATTATGAAGGATCGCCAAACTTTAATTGATATTACAACACGAGGTTTA
GAAGGTTTGGATAAAGTAATGAAAGAAGCAAAGCCGGATATCGTACTTGTACATGGTGATACAACGACAACGTTTATCGC
AAGCTTAGCTGCTTTCTATAATCAAATTCCAGTAGGTCATGTCGAGGCGGGACTTCGTACATGGGATAAATATTCTCCAT
ACCCAGAAGAGATGAATCGTCAATTAACAGGCGTAATGGCGGACCTTCATTTCTCACCTACAGCAAAATCGGCAACGAAC
TTACAGAAAGAAAATAAAGATGAGTCACGCATTTTCATAACAGGAAATACAGCGATTGACGCACTAAAAACGACTGTAAA
AGAAACATATAGTCATCCTGTACTAGAGAAACTTGGAAATGATCGTCTTGTACTTATGACAGCTCACCGTCGTGAAAACT
TAGGAGAGCCAATGCGTAATATGTTCCGTGCAATTAAGCGTCTTGTTGATAAGCATGAAGACGTACAAGTTGTATATCCT
GTTCATATGAATCCTGTTGTTCGTGAAACTGCAAATGATATTTTAGGCGATCATGGCCGCATTCATTTAATTGAGCCGTT
AGATGTAATTGATTTCCACAATGTTGCAGCTCGTTCATACTTAATGTTAACTGATTCTGGTGGGGTACAAGAGGAAGCTC
CGTCACTTGGTGTACCGGCTCTTGTTCTTCGTGATACAACAGAGCGCCCTGAAGGTATTGAAGCAGGTACGTTGAAATTA
GCGGGAACAGACGAAGAGACAATCTTTAGTCTTGCTGATGAGTTGTTATCAGACAAAGAAGCTCATGATAAAATGTCAAA
AGCATCTAACCCGTACGGTGATGGCCGTGCATCAGAGCGTATTGTAGAAGCAATTTTAAAACACTTTAATAAGTAA

Upstream 100 bases:

>100_bases
AGAGGGATTTTTCCGTTATTCGTTAAAAAGGTATGTATTCATGTATATTCTTATATGTCATAATAGGATTTGTAACTAGT
GAAAGAAAAGAGGCAATGAA

Downstream 100 bases:

>100_bases
AAAAAGCCAAATCGCATGCGATTTGGCCTTTTTTTATTGCTGATTTCTCATAATCCACTCTGCATGAGCATTCGTAGAAG
GAGGGGGATCAGTTGGTGTT

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MTERLKVMTIFGTRPEAIKMAPLVLELQKHPEKIESIVTVTAQHRQMLDQVLSIFGITPDFDLNIMKDRQTLIDITTRGL
EGLDKVMKEAKPDIVLVHGDTTTTFIASLAAFYNQIPVGHVEAGLRTWDKYSPYPEEMNRQLTGVMADLHFSPTAKSATN
LQKENKDESRIFITGNTAIDALKTTVKETYSHPVLEKLGNDRLVLMTAHRRENLGEPMRNMFRAIKRLVDKHEDVQVVYP
VHMNPVVRETANDILGDHGRIHLIEPLDVIDFHNVAARSYLMLTDSGGVQEEAPSLGVPALVLRDTTERPEGIEAGTLKL
AGTDEETIFSLADELLSDKEAHDKMSKASNPYGDGRASERIVEAILKHFNK

Sequences:

>Translated_371_residues
MTERLKVMTIFGTRPEAIKMAPLVLELQKHPEKIESIVTVTAQHRQMLDQVLSIFGITPDFDLNIMKDRQTLIDITTRGL
EGLDKVMKEAKPDIVLVHGDTTTTFIASLAAFYNQIPVGHVEAGLRTWDKYSPYPEEMNRQLTGVMADLHFSPTAKSATN
LQKENKDESRIFITGNTAIDALKTTVKETYSHPVLEKLGNDRLVLMTAHRRENLGEPMRNMFRAIKRLVDKHEDVQVVYP
VHMNPVVRETANDILGDHGRIHLIEPLDVIDFHNVAARSYLMLTDSGGVQEEAPSLGVPALVLRDTTERPEGIEAGTLKL
AGTDEETIFSLADELLSDKEAHDKMSKASNPYGDGRASERIVEAILKHFNK
>Mature_370_residues
TERLKVMTIFGTRPEAIKMAPLVLELQKHPEKIESIVTVTAQHRQMLDQVLSIFGITPDFDLNIMKDRQTLIDITTRGLE
GLDKVMKEAKPDIVLVHGDTTTTFIASLAAFYNQIPVGHVEAGLRTWDKYSPYPEEMNRQLTGVMADLHFSPTAKSATNL
QKENKDESRIFITGNTAIDALKTTVKETYSHPVLEKLGNDRLVLMTAHRRENLGEPMRNMFRAIKRLVDKHEDVQVVYPV
HMNPVVRETANDILGDHGRIHLIEPLDVIDFHNVAARSYLMLTDSGGVQEEAPSLGVPALVLRDTTERPEGIEAGTLKLA
GTDEETIFSLADELLSDKEAHDKMSKASNPYGDGRASERIVEAILKHFNK

Specific function: Catalyzes the conversion of UDP-N-acetylglucosamine into UDP-N-acetylmannosamine, a precursor of the teichoic acid linkage unit [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=372, Percent_Identity=54.3010752688172, Blast_Score=380, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 41566; Mature: 41435

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTERLKVMTIFGTRPEAIKMAPLVLELQKHPEKIESIVTVTAQHRQMLDQVLSIFGITPD
CCCCEEEEEEECCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FDLNIMKDRQTLIDITTRGLEGLDKVMKEAKPDIVLVHGDTTTTFIASLAAFYNQIPVGH
CCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCH
VEAGLRTWDKYSPYPEEMNRQLTGVMADLHFSPTAKSATNLQKENKDESRIFITGNTAID
HHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCEEEEECCHHHH
ALKTTVKETYSHPVLEKLGNDRLVLMTAHRRENLGEPMRNMFRAIKRLVDKHEDVQVVYP
HHHHHHHHHHCCHHHHHCCCCCEEEEECHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEE
VHMNPVVRETANDILGDHGRIHLIEPLDVIDFHNVAARSYLMLTDSGGVQEEAPSLGVPA
CCCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCE
LVLRDTTERPEGIEAGTLKLAGTDEETIFSLADELLSDKEAHDKMSKASNPYGDGRASER
EEEECCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHH
IVEAILKHFNK
HHHHHHHHHCC
>Mature Secondary Structure 
TERLKVMTIFGTRPEAIKMAPLVLELQKHPEKIESIVTVTAQHRQMLDQVLSIFGITPD
CCCEEEEEEECCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FDLNIMKDRQTLIDITTRGLEGLDKVMKEAKPDIVLVHGDTTTTFIASLAAFYNQIPVGH
CCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCH
VEAGLRTWDKYSPYPEEMNRQLTGVMADLHFSPTAKSATNLQKENKDESRIFITGNTAID
HHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCEEEEECCHHHH
ALKTTVKETYSHPVLEKLGNDRLVLMTAHRRENLGEPMRNMFRAIKRLVDKHEDVQVVYP
HHHHHHHHHHCCHHHHHCCCCCEEEEECHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEE
VHMNPVVRETANDILGDHGRIHLIEPLDVIDFHNVAARSYLMLTDSGGVQEEAPSLGVPA
CCCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCE
LVLRDTTERPEGIEAGTLKLAGTDEETIFSLADELLSDKEAHDKMSKASNPYGDGRASER
EEEECCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHH
IVEAILKHFNK
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8126437; 12107153; 9384377 [H]